N-[5-[2-(6-amino-3-pyridinyl)-5-methyl-1,3-thiazol-4-yl]pyrazin-2-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[4-[5-methyl-2-(1,3-oxazol-5-yl)-1,3-thiazol-4-yl]phenyl]benzamide;2,6-difluoro-N-[4-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)phenyl]benzamide;2-fluoro-6-methyl-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide

C102H74F9N23O6S5 — CID 158671260

IUPACN-[5-[2-(6-amino-3-pyridinyl)-5-methyl-1,3-thiazol-4-yl]pyrazin-2-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[4-[5-methyl-2-(1,3-oxazol-5-yl)-1,3-thiazol-4-yl]phenyl]benzamide;2,6-difluoro-N-[4-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)phenyl]benzamide;2-fluoro-6-methyl-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide
SMILESCc1cccc(F)c1C(=O)Nc1ccc(-c2nc(-c3cnn(C)c3)sc2C)cn1.Cc1sc(-c2ccc(N)nc2)nc1-c1cnc(NC(=O)c2c(F)cccc2F)cn1.Cc1sc(-c2cccnc2)nc1-c1ccc(NC(=O)c2c(F)cccc2F)cc1.Cc1sc(-c2cnco2)nc1-c1ccc(NC(=O)c2c(F)cccc2F)cc1.Cc1sc(-c2cnn(C)c2)nc1-c1cnc(NC(=O)c2c(F)cccc2F)cn1
InChIInChI=1S/C22H15F2N3OS.C21H18FN5OS.C20H14F2N6OS.C20H13F2N3O2S.C19H14F2N6OS/c1-13-20(27-22(29-13)15-4-3-11-25-12-15)14-7-9-16(10-8-14)26-21(28)19-17(23)5-2-6-18(19)24;1-12-5-4-6-16(22)18(12)20(28)25-17-8-7-14(9-23-17)19-13(2)29-21(26-19)15-10-24-27(3)11-15;1-10-18(28-20(30-10)11-5-6-15(23)25-7-11)14-8-26-16(9-24-14)27-19(29)17-12(21)3-2-4-13(17)22;1-11-18(25-20(28-11)16-9-23-10-27-16)12-5-7-13(8-6-12)24-19(26)17-14(21)3-2-4-15(17)22;1-10-17(26-19(29-10)11-6-24-27(2)9-11)14-7-23-15(8-22-14)25-18(28)16-12(20)4-3-5-13(16)21/h2-12H,1H3,(H,26,28);4-11H,1-3H3,(H,23,25,28);2-9H,1H3,(H2,23,25)(H,26,27,29);2-10H,1H3,(H,24,26);3-9H,1-2H3,(H,23,25,28)
InChIKeyIDZBPYUNFJAFHZ-UHFFFAOYSA-N
MW2049.19 g/mol
LogP23.55
Rot. Bonds20

About N-[5-[2-(6-amino-3-pyridinyl)-5-methyl-1,3-thiazol-4-yl]pyrazin-2-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[4-[5-methyl-2-(1,3-oxazol-5-yl)-1,3-thiazol-4-yl]phenyl]benzamide;2,6-difluoro-N-[4-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)phenyl]benzamide;2-fluoro-6-methyl-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide

N-[5-[2-(6-amino-3-pyridinyl)-5-methyl-1,3-thiazol-4-yl]pyrazin-2-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[4-[5-methyl-2-(1,3-oxazol-5-yl)-1,3-thiazol-4-yl]phenyl]benzamide;2,6-difluoro-N-[4-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)phenyl]benzamide;2-fluoro-6-methyl-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide (PubChem CID 158671260) has the molecular formula C102H74F9N23O6S5 and a molecular weight of 2049.19 g/mol. Its IUPAC name is N-[5-[2-(6-amino-3-pyridinyl)-5-methyl-1,3-thiazol-4-yl]pyrazin-2-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[4-[5-methyl-2-(1,3-oxazol-5-yl)-1,3-thiazol-4-yl]phenyl]benzamide;2,6-difluoro-N-[4-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)phenyl]benzamide;2-fluoro-6-methyl-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide.

Molecular Properties

Compound NameN-[5-[2-(6-amino-3-pyridinyl)-5-methyl-1,3-thiazol-4-yl]pyrazin-2-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[4-[5-methyl-2-(1,3-oxazol-5-yl)-1,3-thiazol-4-yl]phenyl]benzamide;2,6-difluoro-N-[4-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)phenyl]benzamide;2-fluoro-6-methyl-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide
PubChem CID158671260
Molecular FormulaC102H74F9N23O6S5
Molecular Weight2049.19 g/mol
Exact Mass2047.47
IUPAC NameN-[5-[2-(6-amino-3-pyridinyl)-5-methyl-1,3-thiazol-4-yl]pyrazin-2-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[4-[5-methyl-2-(1,3-oxazol-5-yl)-1,3-thiazol-4-yl]phenyl]benzamide;2,6-difluoro-N-[4-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)phenyl]benzamide;2-fluoro-6-methyl-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide
SMILESCc1cccc(F)c1C(=O)Nc1ccc(-c2nc(-c3cnn(C)c3)sc2C)cn1.Cc1sc(-c2ccc(N)nc2)nc1-c1cnc(NC(=O)c2c(F)cccc2F)cn1.Cc1sc(-c2cccnc2)nc1-c1ccc(NC(=O)c2c(F)cccc2F)cc1.Cc1sc(-c2cnco2)nc1-c1ccc(NC(=O)c2c(F)cccc2F)cc1.Cc1sc(-c2cnn(C)c2)nc1-c1cnc(NC(=O)c2c(F)cccc2F)cn1
InChIInChI=1S/C22H15F2N3OS.C21H18FN5OS.C20H14F2N6OS.C20H13F2N3O2S.C19H14F2N6OS/c1-13-20(27-22(29-13)15-4-3-11-25-12-15)14-7-9-16(10-8-14)26-21(28)19-17(23)5-2-6-18(19)24;1-12-5-4-6-16(22)18(12)20(28)25-17-8-7-14(9-23-17)19-13(2)29-21(26-19)15-10-24-27(3)11-15;1-10-18(28-20(30-10)11-5-6-15(23)25-7-11)14-8-26-16(9-24-14)27-19(29)17-12(21)3-2-4-13(17)22;1-11-18(25-20(28-11)16-9-23-10-27-16)12-5-7-13(8-6-12)24-19(26)17-14(21)3-2-4-15(17)22;1-10-17(26-19(29-10)11-6-24-27(2)9-11)14-7-23-15(8-22-14)25-18(28)16-12(20)4-3-5-13(16)21/h2-12H,1H3,(H,26,28);4-11H,1-3H3,(H,23,25,28);2-9H,1H3,(H2,23,25)(H,26,27,29);2-10H,1H3,(H,24,26);3-9H,1-2H3,(H,23,25,28)
InChIKeyIDZBPYUNFJAFHZ-UHFFFAOYSA-N
XLogP23.55
TPSA387.87 Ų
H-Bond Donors6
H-Bond Acceptors29
Rotatable Bonds20
Heavy Atoms145
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002049.19
LogP ≤ 523.55
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1029

Analyze N-[5-[2-(6-amino-3-pyridinyl)-5-methyl-1,3-thiazol-4-yl]pyrazin-2-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[4-[5-methyl-2-(1,3-oxazol-5-yl)-1,3-thiazol-4-yl]phenyl]benzamide;2,6-difluoro-N-[4-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)phenyl]benzamide;2-fluoro-6-methyl-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of N-[5-[2-(6-amino-3-pyridinyl)-5-methyl-1,3-thiazol-4-yl]pyrazin-2-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[4-[5-methyl-2-(1,3-oxazol-5-yl)-1,3-thiazol-4-yl]phenyl]benzamide;2,6-difluoro-N-[4-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)phenyl]benzamide;2-fluoro-6-methyl-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide?
The IUPAC name of N-[5-[2-(6-amino-3-pyridinyl)-5-methyl-1,3-thiazol-4-yl]pyrazin-2-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[4-[5-methyl-2-(1,3-oxazol-5-yl)-1,3-thiazol-4-yl]phenyl]benzamide;2,6-difluoro-N-[4-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)phenyl]benzamide;2-fluoro-6-methyl-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide (CID 158671260) is N-[5-[2-(6-amino-3-pyridinyl)-5-methyl-1,3-thiazol-4-yl]pyrazin-2-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[4-[5-methyl-2-(1,3-oxazol-5-yl)-1,3-thiazol-4-yl]phenyl]benzamide;2,6-difluoro-N-[4-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)phenyl]benzamide;2-fluoro-6-methyl-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide.
What is the SMILES notation for N-[5-[2-(6-amino-3-pyridinyl)-5-methyl-1,3-thiazol-4-yl]pyrazin-2-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[4-[5-methyl-2-(1,3-oxazol-5-yl)-1,3-thiazol-4-yl]phenyl]benzamide;2,6-difluoro-N-[4-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)phenyl]benzamide;2-fluoro-6-methyl-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide?
The canonical SMILES for N-[5-[2-(6-amino-3-pyridinyl)-5-methyl-1,3-thiazol-4-yl]pyrazin-2-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[4-[5-methyl-2-(1,3-oxazol-5-yl)-1,3-thiazol-4-yl]phenyl]benzamide;2,6-difluoro-N-[4-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)phenyl]benzamide;2-fluoro-6-methyl-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide is Cc1cccc(F)c1C(=O)Nc1ccc(-c2nc(-c3cnn(C)c3)sc2C)cn1.Cc1sc(-c2ccc(N)nc2)nc1-c1cnc(NC(=O)c2c(F)cccc2F)cn1.Cc1sc(-c2cccnc2)nc1-c1ccc(NC(=O)c2c(F)cccc2F)cc1.Cc1sc(-c2cnco2)nc1-c1ccc(NC(=O)c2c(F)cccc2F)cc1.Cc1sc(-c2cnn(C)c2)nc1-c1cnc(NC(=O)c2c(F)cccc2F)cn1.
What is the InChIKey of N-[5-[2-(6-amino-3-pyridinyl)-5-methyl-1,3-thiazol-4-yl]pyrazin-2-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[4-[5-methyl-2-(1,3-oxazol-5-yl)-1,3-thiazol-4-yl]phenyl]benzamide;2,6-difluoro-N-[4-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)phenyl]benzamide;2-fluoro-6-methyl-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide?
The InChIKey is IDZBPYUNFJAFHZ-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H15F2N3OS.C21H18FN5OS.C20H14F2N6OS.C20H13F2N3O2S.C19H14F2N6OS/c1-13-20(27-22(29-13)15-4-3-11-25-12-15)14-7-9-16(10-8-14)26-21(28)19-17(23)5-2-6-18(19)24;1-12-5-4-6-16(22)18(12)20(28)25-17-8-7-14(9-23-17)19-13(2)29-21(26-19)15-10-24-27(3)11-15;1-10-18(28-20(30-10)11-5-6-15(23)25-7-11)14-8-26-16(9-24-14)27-19(29)17-12(21)3-2-4-13(17)22;1-11-18(25-20(28-11)16-9-23-10-27-16)12-5-7-13(8-6-12)24-19(26)17-14(21)3-2-4-15(17)22;1-10-17(26-19(29-10)11-6-24-27(2)9-11)14-7-23-15(8-22-14)25-18(28)16-12(20)4-3-5-13(16)21/h2-12H,1H3,(H,26,28);4-11H,1-3H3,(H,23,25,28);2-9H,1H3,(H2,23,25)(H,26,27,29);2-10H,1H3,(H,24,26);3-9H,1-2H3,(H,23,25,28).
What are the key properties of N-[5-[2-(6-amino-3-pyridinyl)-5-methyl-1,3-thiazol-4-yl]pyrazin-2-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[4-[5-methyl-2-(1,3-oxazol-5-yl)-1,3-thiazol-4-yl]phenyl]benzamide;2,6-difluoro-N-[4-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)phenyl]benzamide;2-fluoro-6-methyl-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide?
N-[5-[2-(6-amino-3-pyridinyl)-5-methyl-1,3-thiazol-4-yl]pyrazin-2-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[4-[5-methyl-2-(1,3-oxazol-5-yl)-1,3-thiazol-4-yl]phenyl]benzamide;2,6-difluoro-N-[4-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)phenyl]benzamide;2-fluoro-6-methyl-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide has a molecular weight of 2049.19 g/mol, XLogP of 23.55, 20 rotatable bonds, 6 hydrogen bond donors, and 29 hydrogen bond acceptors.
Where does this data come from?
All data for N-[5-[2-(6-amino-3-pyridinyl)-5-methyl-1,3-thiazol-4-yl]pyrazin-2-yl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[4-[5-methyl-2-(1,3-oxazol-5-yl)-1,3-thiazol-4-yl]phenyl]benzamide;2,6-difluoro-N-[4-(5-methyl-2-pyridin-3-yl-1,3-thiazol-4-yl)phenyl]benzamide;2-fluoro-6-methyl-N-[5-[5-methyl-2-(1-methylpyrazol-4-yl)-1,3-thiazol-4-yl]-2-pyridinyl]benzamide is sourced from PubChem (CID 158671260), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).