N-(4-piperazin-1-yl-3-pyridinyl)-6-(6-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-3-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-4-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyrimidin-5-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-thiophen-3-ylpyridine-2-carboxamide

C102H106N32O5S — CID 158685262

IUPACN-(4-piperazin-1-yl-3-pyridinyl)-6-(6-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-3-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-4-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyrimidin-5-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-thiophen-3-ylpyridine-2-carboxamide
SMILESO=C(Nc1cnccc1N1CCNCC1)c1cccc(-c2cccc(N3CCNCC3)n2)n1.O=C(Nc1cnccc1N1CCNCC1)c1cccc(-c2cccnc2)n1.O=C(Nc1cnccc1N1CCNCC1)c1cccc(-c2ccncc2)n1.O=C(Nc1cnccc1N1CCNCC1)c1cccc(-c2ccsc2)n1.O=C(Nc1cnccc1N1CCNCC1)c1cccc(-c2cncnc2)n1
InChIInChI=1S/C24H28N8O.2C20H20N6O.C19H19N7O.C19H19N5OS/c33-24(30-21-17-27-8-7-22(21)31-13-9-25-10-14-31)20-5-1-3-18(28-20)19-4-2-6-23(29-19)32-15-11-26-12-16-32;27-20(17-5-1-4-16(24-17)15-3-2-7-22-13-15)25-18-14-23-8-6-19(18)26-11-9-21-10-12-26;27-20(17-3-1-2-16(24-17)15-4-7-21-8-5-15)25-18-14-23-9-6-19(18)26-12-10-22-11-13-26;27-19(16-3-1-2-15(24-16)14-10-22-13-23-11-14)25-17-12-21-5-4-18(17)26-8-6-20-7-9-26;25-19(16-3-1-2-15(22-16)14-5-11-26-13-14)23-17-12-21-6-4-18(17)24-9-7-20-8-10-24/h1-8,17,25-26H,9-16H2,(H,30,33);1-8,13-14,21H,9-12H2,(H,25,27);1-9,14,22H,10-13H2,(H,25,27);1-5,10-13,20H,6-9H2,(H,25,27);1-6,11-13,20H,7-10H2,(H,23,25)
InChIKeyIFQRXNYBAUWRTQ-UHFFFAOYSA-N
MW1892.26 g/mol
LogP10.47
Rot. Bonds21

About N-(4-piperazin-1-yl-3-pyridinyl)-6-(6-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-3-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-4-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyrimidin-5-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-thiophen-3-ylpyridine-2-carboxamide

N-(4-piperazin-1-yl-3-pyridinyl)-6-(6-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-3-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-4-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyrimidin-5-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-thiophen-3-ylpyridine-2-carboxamide (PubChem CID 158685262) has the molecular formula C102H106N32O5S and a molecular weight of 1892.26 g/mol. Its IUPAC name is N-(4-piperazin-1-yl-3-pyridinyl)-6-(6-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-3-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-4-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyrimidin-5-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-thiophen-3-ylpyridine-2-carboxamide.

Molecular Properties

Compound NameN-(4-piperazin-1-yl-3-pyridinyl)-6-(6-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-3-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-4-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyrimidin-5-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-thiophen-3-ylpyridine-2-carboxamide
PubChem CID158685262
Molecular FormulaC102H106N32O5S
Molecular Weight1892.26 g/mol
Exact Mass1890.87
IUPAC NameN-(4-piperazin-1-yl-3-pyridinyl)-6-(6-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-3-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-4-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyrimidin-5-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-thiophen-3-ylpyridine-2-carboxamide
SMILESO=C(Nc1cnccc1N1CCNCC1)c1cccc(-c2cccc(N3CCNCC3)n2)n1.O=C(Nc1cnccc1N1CCNCC1)c1cccc(-c2cccnc2)n1.O=C(Nc1cnccc1N1CCNCC1)c1cccc(-c2ccncc2)n1.O=C(Nc1cnccc1N1CCNCC1)c1cccc(-c2ccsc2)n1.O=C(Nc1cnccc1N1CCNCC1)c1cccc(-c2cncnc2)n1
InChIInChI=1S/C24H28N8O.2C20H20N6O.C19H19N7O.C19H19N5OS/c33-24(30-21-17-27-8-7-22(21)31-13-9-25-10-14-31)20-5-1-3-18(28-20)19-4-2-6-23(29-19)32-15-11-26-12-16-32;27-20(17-5-1-4-16(24-17)15-3-2-7-22-13-15)25-18-14-23-8-6-19(18)26-11-9-21-10-12-26;27-20(17-3-1-2-16(24-17)15-4-7-21-8-5-15)25-18-14-23-9-6-19(18)26-12-10-22-11-13-26;27-19(16-3-1-2-15(24-16)14-10-22-13-23-11-14)25-17-12-21-5-4-18(17)26-8-6-20-7-9-26;25-19(16-3-1-2-15(22-16)14-5-11-26-13-14)23-17-12-21-6-4-18(17)24-9-7-20-8-10-24/h1-8,17,25-26H,9-16H2,(H,30,33);1-8,13-14,21H,9-12H2,(H,25,27);1-9,14,22H,10-13H2,(H,25,27);1-5,10-13,20H,6-9H2,(H,25,27);1-6,11-13,20H,7-10H2,(H,23,25)
InChIKeyIFQRXNYBAUWRTQ-UHFFFAOYSA-N
XLogP10.47
TPSA430.47 Ų
H-Bond Donors11
H-Bond Acceptors33
Rotatable Bonds21
Heavy Atoms140
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001892.26
LogP ≤ 510.47
H-Bond Donors ≤ 511
H-Bond Acceptors ≤ 1033

Analyze N-(4-piperazin-1-yl-3-pyridinyl)-6-(6-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-3-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-4-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyrimidin-5-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-thiophen-3-ylpyridine-2-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

6-cyclopropyl-N-(5-pyridin-2-ylthiophen-2-yl)-3-(pyrimidin-5-ylamino)pyridine-2-carboxamide
CID 53329709
6-cyclopropyl-N-[3-(morpholine-4-carbonyl)thiophen-2-yl]-3-(pyrimidin-5-ylamino)pyridine-2-carboxamide
CID 54761301
6-cyclopropyl-N-[3-(cyclopropylcarbamoyl)thiophen-2-yl]-3-(pyrimidin-5-ylamino)pyridine-2-carboxamide
CID 58548356
3-amino-N-[3-(4-aminopiperidin-1-yl)-2-pyridinyl]-6-thieno[2,3-d]pyrimidin-4-ylpyrazine-2-carboxamide
CID 118875852
3-amino-N-[4-(2-amino-6-methylpyrimidin-4-yl)-3-pyridinyl]-6-(1,3-thiazol-2-yl)pyridine-2-carboxamide
CID 127032072
Fovinaciclib
CID 132136461
6-cyclopropyl-N-[5-[[(1R)-1-phenylethyl]carbamoyl]thiophen-2-yl]-3-(pyrimidin-5-ylamino)pyridine-2-carboxamide
CID 165415097
N-[[(2R,4S,5R)-5-(6-pentan-3-yl-2-pyridin-4-ylpyrimidin-4-yl)-1-azabicyclo[2.2.2]octan-2-yl]methyl]-2-thiophen-2-ylacetamide
CID 26742366
N-[2-(dimethylamino)ethyl]-N-[[4-[[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]carbamoyl]phenyl]methyl]thiophene-2-carboxamide
CID 145984751
N-Cyclopropyl-3-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-ylamino)thieno[3,2-d]pyrimidin-7-yl)benzamide
CID 52931892
N-cyclopropyl-3-[2-[(6-morpholin-4-yl-3-pyridinyl)amino]thieno[3,2-d]pyrimidin-7-yl]benzamide
CID 52931894
(4-Methylpiperazin-1-yl)-[5-[(4-pyridin-2-ylpyrimidin-2-yl)amino]-1-benzothiophen-2-yl]methanone
CID 60141510

Frequently Asked Questions

What is the IUPAC name of N-(4-piperazin-1-yl-3-pyridinyl)-6-(6-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-3-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-4-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyrimidin-5-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-thiophen-3-ylpyridine-2-carboxamide?
The IUPAC name of N-(4-piperazin-1-yl-3-pyridinyl)-6-(6-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-3-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-4-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyrimidin-5-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-thiophen-3-ylpyridine-2-carboxamide (CID 158685262) is N-(4-piperazin-1-yl-3-pyridinyl)-6-(6-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-3-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-4-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyrimidin-5-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-thiophen-3-ylpyridine-2-carboxamide.
What is the SMILES notation for N-(4-piperazin-1-yl-3-pyridinyl)-6-(6-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-3-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-4-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyrimidin-5-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-thiophen-3-ylpyridine-2-carboxamide?
The canonical SMILES for N-(4-piperazin-1-yl-3-pyridinyl)-6-(6-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-3-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-4-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyrimidin-5-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-thiophen-3-ylpyridine-2-carboxamide is O=C(Nc1cnccc1N1CCNCC1)c1cccc(-c2cccc(N3CCNCC3)n2)n1.O=C(Nc1cnccc1N1CCNCC1)c1cccc(-c2cccnc2)n1.O=C(Nc1cnccc1N1CCNCC1)c1cccc(-c2ccncc2)n1.O=C(Nc1cnccc1N1CCNCC1)c1cccc(-c2ccsc2)n1.O=C(Nc1cnccc1N1CCNCC1)c1cccc(-c2cncnc2)n1.
What is the InChIKey of N-(4-piperazin-1-yl-3-pyridinyl)-6-(6-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-3-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-4-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyrimidin-5-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-thiophen-3-ylpyridine-2-carboxamide?
The InChIKey is IFQRXNYBAUWRTQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H28N8O.2C20H20N6O.C19H19N7O.C19H19N5OS/c33-24(30-21-17-27-8-7-22(21)31-13-9-25-10-14-31)20-5-1-3-18(28-20)19-4-2-6-23(29-19)32-15-11-26-12-16-32;27-20(17-5-1-4-16(24-17)15-3-2-7-22-13-15)25-18-14-23-8-6-19(18)26-11-9-21-10-12-26;27-20(17-3-1-2-16(24-17)15-4-7-21-8-5-15)25-18-14-23-9-6-19(18)26-12-10-22-11-13-26;27-19(16-3-1-2-15(24-16)14-10-22-13-23-11-14)25-17-12-21-5-4-18(17)26-8-6-20-7-9-26;25-19(16-3-1-2-15(22-16)14-5-11-26-13-14)23-17-12-21-6-4-18(17)24-9-7-20-8-10-24/h1-8,17,25-26H,9-16H2,(H,30,33);1-8,13-14,21H,9-12H2,(H,25,27);1-9,14,22H,10-13H2,(H,25,27);1-5,10-13,20H,6-9H2,(H,25,27);1-6,11-13,20H,7-10H2,(H,23,25).
What are the key properties of N-(4-piperazin-1-yl-3-pyridinyl)-6-(6-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-3-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-4-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyrimidin-5-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-thiophen-3-ylpyridine-2-carboxamide?
N-(4-piperazin-1-yl-3-pyridinyl)-6-(6-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-3-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-4-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyrimidin-5-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-thiophen-3-ylpyridine-2-carboxamide has a molecular weight of 1892.26 g/mol, XLogP of 10.47, 21 rotatable bonds, 11 hydrogen bond donors, and 33 hydrogen bond acceptors.
Where does this data come from?
All data for N-(4-piperazin-1-yl-3-pyridinyl)-6-(6-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-3-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyridin-4-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-pyrimidin-5-ylpyridine-2-carboxamide;N-(4-piperazin-1-yl-3-pyridinyl)-6-thiophen-3-ylpyridine-2-carboxamide is sourced from PubChem (CID 158685262), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).