2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1-methylpyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aR,6aR)-1-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;5-[2-fluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(2-methoxy-4-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(6-methoxy-3-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-(2-methoxy-4-pyridin-3-ylphenyl)-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine

C150H183Cl3FN39O5S7 — CID 158687008

About 2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1-methylpyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aR,6aR)-1-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;5-[2-fluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(2-methoxy-4-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(6-methoxy-3-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-(2-methoxy-4-pyridin-3-ylphenyl)-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine

2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1-methylpyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aR,6aR)-1-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;5-[2-fluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(2-methoxy-4-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(6-methoxy-3-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-(2-methoxy-4-pyridin-3-ylphenyl)-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine (PubChem CID 158687008) has the molecular formula C150H183Cl3FN39O5S7 and a molecular weight of 2962.21 g/mol. Its IUPAC name is 2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1-methylpyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aR,6aR)-1-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;5-[2-fluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(2-methoxy-4-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(6-methoxy-3-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-(2-methoxy-4-pyridin-3-ylphenyl)-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine.

Molecular Properties

• Compound Name: 2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1-methylpyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aR,6aR)-1-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;5-[2-fluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(2-methoxy-4-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(6-methoxy-3-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-(2-methoxy-4-pyridin-3-ylphenyl)-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine
• PubChem CID: 158687008
• Molecular Formula: C150H183Cl3FN39O5S7
• Molecular Weight: 2962.21 g/mol
• Exact Mass: 2958.24
• IUPAC Name: 2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1-methylpyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aR,6aR)-1-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;5-[2-fluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(2-methoxy-4-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(6-methoxy-3-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-(2-methoxy-4-pyridin-3-ylphenyl)-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine
• SMILES: CN(c1nnc(-c2ccc(-c3cn[nH]c3)cc2F)s1)C1CC(C)(C)NC(C)(C)C1.CN1CC[C@@H]2CN(c3nnc(-c4ccc(-c5cn[nH]c5)cc4Cl)s3)C[C@@H]21.CN1C[C@@H]2CN(c3nnc(-c4ccc(-c5cn[nH]c5)cc4Cl)s3)C[C@@H]2C1.CN1C[C@@H]2CN(c3nnc(-c4ccc(-c5cnn(C)c5)cc4Cl)s3)C[C@@H]2C1.COc1cc(-c2ccc(-c3nnc(N(C)C4CC(C)(C)NC(C)(C)C4)s3)c(OC)c2)ccn1.COc1cc(-c2cccnc2)ccc1-c1nnc(N(C)C2CC(C)(C)NC(C)(C)C2)s1.COc1ccc(-c2ccc(-c3nnc(N(C)C4CC(C)(C)NC(C)(C)C4)s3)c(OC)c2)cn1
• InChI: InChI=1S/2C25H33N5O2S.C24H31N5OS.C21H27FN6S.C19H21ClN6S.2C18H19ClN6S/c1-24(2)13-18(14-25(3,4)29-24)30(5)23-28-27-22(33-23)19-10-8-16(12-20(19)31-6)17-9-11-21(32-7)26-15-17;1-24(2)14-18(15-25(3,4)29-24)30(5)23-28-27-22(33-23)19-9-8-16(12-20(19)31-6)17-10-11-26-21(13-17)32-7;1-23(2)13-18(14-24(3,4)28-23)29(5)22-27-26-21(31-22)19-10-9-16(12-20(19)30-6)17-8-7-11-25-15-17;1-20(2)9-15(10-21(3,4)27-20)28(5)19-26-25-18(29-19)16-7-6-13(8-17(16)22)14-11-23-24-12-14;1-24-7-14-10-26(11-15(14)8-24)19-23-22-18(27-19)16-4-3-12(5-17(16)20)13-6-21-25(2)9-13;1-24-7-13-9-25(10-14(13)8-24)18-23-22-17(26-18)15-3-2-11(4-16(15)19)12-5-20-21-6-12;1-24-5-4-12-9-25(10-16(12)24)18-23-22-17(26-18)14-3-2-11(6-15(14)19)13-7-20-21-8-13/h8-12,15,18,29H,13-14H2,1-7H3;8-13,18,29H,14-15H2,1-7H3;7-12,15,18,28H,13-14H2,1-6H3;6-8,11-12,15,27H,9-10H2,1-5H3,(H,23,24);3-6,9,14-15H,7-8,10-11H2,1-2H3;2-6,13-14H,7-10H2,1H3,(H,20,21);2-3,6-8,12,16H,4-5,9-10H2,1H3,(H,20,21)/t;;;;14-,15+;13-,14+;12-,16+/m......1/s1
• InChIKey: IFWGRFWLEVZHCB-OQVXXWCASA-N
• XLogP: 29.45
• TPSA: 449.66 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 48
• Rotatable Bonds: 30
• Heavy Atoms: 205
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2962.21
LogP ≤ 5	29.45
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	48

Frequently Asked Questions

What is the IUPAC name of 2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1-methylpyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aR,6aR)-1-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;5-[2-fluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(2-methoxy-4-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(6-methoxy-3-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-(2-methoxy-4-pyridin-3-ylphenyl)-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine?

The IUPAC name of 2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1-methylpyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aR,6aR)-1-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;5-[2-fluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(2-methoxy-4-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(6-methoxy-3-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-(2-methoxy-4-pyridin-3-ylphenyl)-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine (CID 158687008) is 2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1-methylpyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aR,6aR)-1-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;5-[2-fluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(2-methoxy-4-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(6-methoxy-3-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-(2-methoxy-4-pyridin-3-ylphenyl)-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine.

What is the SMILES notation for 2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1-methylpyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aR,6aR)-1-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;5-[2-fluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(2-methoxy-4-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(6-methoxy-3-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-(2-methoxy-4-pyridin-3-ylphenyl)-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine?

The canonical SMILES for 2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1-methylpyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aR,6aR)-1-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;5-[2-fluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(2-methoxy-4-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(6-methoxy-3-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-(2-methoxy-4-pyridin-3-ylphenyl)-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine is CN(c1nnc(-c2ccc(-c3cn[nH]c3)cc2F)s1)C1CC(C)(C)NC(C)(C)C1.CN1CC[C@@H]2CN(c3nnc(-c4ccc(-c5cn[nH]c5)cc4Cl)s3)C[C@@H]21.CN1C[C@@H]2CN(c3nnc(-c4ccc(-c5cn[nH]c5)cc4Cl)s3)C[C@@H]2C1.CN1C[C@@H]2CN(c3nnc(-c4ccc(-c5cnn(C)c5)cc4Cl)s3)C[C@@H]2C1.COc1cc(-c2ccc(-c3nnc(N(C)C4CC(C)(C)NC(C)(C)C4)s3)c(OC)c2)ccn1.COc1cc(-c2cccnc2)ccc1-c1nnc(N(C)C2CC(C)(C)NC(C)(C)C2)s1.COc1ccc(-c2ccc(-c3nnc(N(C)C4CC(C)(C)NC(C)(C)C4)s3)c(OC)c2)cn1.

What is the InChIKey of 2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1-methylpyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aR,6aR)-1-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;5-[2-fluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(2-methoxy-4-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(6-methoxy-3-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-(2-methoxy-4-pyridin-3-ylphenyl)-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine?

The InChIKey is IFWGRFWLEVZHCB-OQVXXWCASA-N. The full InChI is InChI=1S/2C25H33N5O2S.C24H31N5OS.C21H27FN6S.C19H21ClN6S.2C18H19ClN6S/c1-24(2)13-18(14-25(3,4)29-24)30(5)23-28-27-22(33-23)19-10-8-16(12-20(19)31-6)17-9-11-21(32-7)26-15-17;1-24(2)14-18(15-25(3,4)29-24)30(5)23-28-27-22(33-23)19-9-8-16(12-20(19)31-6)17-10-11-26-21(13-17)32-7;1-23(2)13-18(14-24(3,4)28-23)29(5)22-27-26-21(31-22)19-10-9-16(12-20(19)30-6)17-8-7-11-25-15-17;1-20(2)9-15(10-21(3,4)27-20)28(5)19-26-25-18(29-19)16-7-6-13(8-17(16)22)14-11-23-24-12-14;1-24-7-14-10-26(11-15(14)8-24)19-23-22-18(27-19)16-4-3-12(5-17(16)20)13-6-21-25(2)9-13;1-24-7-13-9-25(10-14(13)8-24)18-23-22-17(26-18)15-3-2-11(4-16(15)19)12-5-20-21-6-12;1-24-5-4-12-9-25(10-16(12)24)18-23-22-17(26-18)14-3-2-11(6-15(14)19)13-7-20-21-8-13/h8-12,15,18,29H,13-14H2,1-7H3;8-13,18,29H,14-15H2,1-7H3;7-12,15,18,28H,13-14H2,1-6H3;6-8,11-12,15,27H,9-10H2,1-5H3,(H,23,24);3-6,9,14-15H,7-8,10-11H2,1-2H3;2-6,13-14H,7-10H2,1H3,(H,20,21);2-3,6-8,12,16H,4-5,9-10H2,1H3,(H,20,21)/t;;;;14-,15+;13-,14+;12-,16+/m......1/s1.

What are the key properties of 2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1-methylpyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aR,6aR)-1-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;5-[2-fluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(2-methoxy-4-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(6-methoxy-3-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-(2-methoxy-4-pyridin-3-ylphenyl)-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine?

2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1-methylpyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aR,6aR)-1-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;5-[2-fluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(2-methoxy-4-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(6-methoxy-3-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-(2-methoxy-4-pyridin-3-ylphenyl)-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine has a molecular weight of 2962.21 g/mol, XLogP of 29.45, 30 rotatable bonds, 7 hydrogen bond donors, and 48 hydrogen bond acceptors.

Where does this data come from?

All data for 2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1-methylpyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aR,6aR)-1-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;2-[(3aS,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-5-[2-chloro-4-(1H-pyrazol-4-yl)phenyl]-1,3,4-thiadiazole;5-[2-fluoro-4-(1H-pyrazol-4-yl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(2-methoxy-4-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-[2-methoxy-4-(6-methoxy-3-pyridinyl)phenyl]-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine;5-(2-methoxy-4-pyridin-3-ylphenyl)-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine is sourced from PubChem (CID 158687008), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).