N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-imidazo[1,2-a]pyridin-3-yl-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(trifluoromethyl)anilino]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;N-[4-(trifluoromethyl)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine

C96H73F26N25O2 — CID 158698219

About N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-imidazo[1,2-a]pyridin-3-yl-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(trifluoromethyl)anilino]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;N-[4-(trifluoromethyl)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine

N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-imidazo[1,2-a]pyridin-3-yl-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(trifluoromethyl)anilino]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;N-[4-(trifluoromethyl)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine (PubChem CID 158698219) has the molecular formula C96H73F26N25O2 and a molecular weight of 2102.76 g/mol. Its IUPAC name is N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-imidazo[1,2-a]pyridin-3-yl-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(trifluoromethyl)anilino]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;N-[4-(trifluoromethyl)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine.

Molecular Properties

• Compound Name: N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-imidazo[1,2-a]pyridin-3-yl-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(trifluoromethyl)anilino]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;N-[4-(trifluoromethyl)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine
• PubChem CID: 158698219
• Molecular Formula: C96H73F26N25O2
• Molecular Weight: 2102.76 g/mol
• Exact Mass: 2101.60
• IUPAC Name: N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-imidazo[1,2-a]pyridin-3-yl-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(trifluoromethyl)anilino]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;N-[4-(trifluoromethyl)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine
• SMILES: FC(F)(F)Oc1ccc(Nc2cncc(-c3c(C(F)(F)F)nc4n3CCCC4)n2)cc1.FC(F)(F)c1ccc(Nc2cncc(-c3c(C(F)(F)F)nc4n3CCCC4)n2)cc1.FC(F)(F)c1ccc(Nc2cncc(-c3cnc4ccccn34)n2)cc1.FC(F)Oc1ccc(Nc2cncc(-c3c(C(F)(F)F)nc4n3CCCC4)n2)cc1.N#Cc1cc(Nc2ccc(C(F)(F)F)cc2)nc(-c2c(C(F)(F)F)nc3n2CCCC3)c1
• InChI: InChI=1S/C21H15F6N5.C19H15F6N5O.C19H15F6N5.C19H16F5N5O.C18H12F3N5/c22-20(23,24)13-4-6-14(7-5-13)29-16-10-12(11-28)9-15(30-16)18-19(21(25,26)27)31-17-3-1-2-8-32(17)18;20-18(21,22)17-16(30-8-2-1-3-15(30)29-17)13-9-26-10-14(28-13)27-11-4-6-12(7-5-11)31-19(23,24)25;20-18(21,22)11-4-6-12(7-5-11)27-14-10-26-9-13(28-14)16-17(19(23,24)25)29-15-3-1-2-8-30(15)16;20-18(21)30-12-6-4-11(5-7-12)26-14-10-25-9-13(27-14)16-17(19(22,23)24)28-15-3-1-2-8-29(15)16;19-18(20,21)12-4-6-13(7-5-12)24-16-11-22-9-14(25-16)15-10-23-17-3-1-2-8-26(15)17/h4-7,9-10H,1-3,8H2,(H,29,30);4-7,9-10H,1-3,8H2,(H,27,28);4-7,9-10H,1-3,8H2,(H,27,28);4-7,9-10,18H,1-3,8H2,(H,26,27);1-11H,(H,24,25)
• InChIKey: IHFCEMFKEKBGFD-UHFFFAOYSA-N
• XLogP: 26.32
• TPSA: 306.99 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 27
• Rotatable Bonds: 18
• Heavy Atoms: 149
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2102.76
LogP ≤ 5	26.32
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	27

Frequently Asked Questions

What is the IUPAC name of N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-imidazo[1,2-a]pyridin-3-yl-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(trifluoromethyl)anilino]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;N-[4-(trifluoromethyl)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine?

The IUPAC name of N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-imidazo[1,2-a]pyridin-3-yl-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(trifluoromethyl)anilino]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;N-[4-(trifluoromethyl)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine (CID 158698219) is N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-imidazo[1,2-a]pyridin-3-yl-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(trifluoromethyl)anilino]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;N-[4-(trifluoromethyl)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine.

What is the SMILES notation for N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-imidazo[1,2-a]pyridin-3-yl-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(trifluoromethyl)anilino]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;N-[4-(trifluoromethyl)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine?

The canonical SMILES for N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-imidazo[1,2-a]pyridin-3-yl-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(trifluoromethyl)anilino]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;N-[4-(trifluoromethyl)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine is FC(F)(F)Oc1ccc(Nc2cncc(-c3c(C(F)(F)F)nc4n3CCCC4)n2)cc1.FC(F)(F)c1ccc(Nc2cncc(-c3c(C(F)(F)F)nc4n3CCCC4)n2)cc1.FC(F)(F)c1ccc(Nc2cncc(-c3cnc4ccccn34)n2)cc1.FC(F)Oc1ccc(Nc2cncc(-c3c(C(F)(F)F)nc4n3CCCC4)n2)cc1.N#Cc1cc(Nc2ccc(C(F)(F)F)cc2)nc(-c2c(C(F)(F)F)nc3n2CCCC3)c1.

What is the InChIKey of N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-imidazo[1,2-a]pyridin-3-yl-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(trifluoromethyl)anilino]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;N-[4-(trifluoromethyl)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine?

The InChIKey is IHFCEMFKEKBGFD-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H15F6N5.C19H15F6N5O.C19H15F6N5.C19H16F5N5O.C18H12F3N5/c22-20(23,24)13-4-6-14(7-5-13)29-16-10-12(11-28)9-15(30-16)18-19(21(25,26)27)31-17-3-1-2-8-32(17)18;20-18(21,22)17-16(30-8-2-1-3-15(30)29-17)13-9-26-10-14(28-13)27-11-4-6-12(7-5-11)31-19(23,24)25;20-18(21,22)11-4-6-12(7-5-11)27-14-10-26-9-13(28-14)16-17(19(23,24)25)29-15-3-1-2-8-30(15)16;20-18(21)30-12-6-4-11(5-7-12)26-14-10-25-9-13(27-14)16-17(19(22,23)24)28-15-3-1-2-8-29(15)16;19-18(20,21)12-4-6-13(7-5-12)24-16-11-22-9-14(25-16)15-10-23-17-3-1-2-8-26(15)17/h4-7,9-10H,1-3,8H2,(H,29,30);4-7,9-10H,1-3,8H2,(H,27,28);4-7,9-10H,1-3,8H2,(H,27,28);4-7,9-10,18H,1-3,8H2,(H,26,27);1-11H,(H,24,25).

What are the key properties of N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-imidazo[1,2-a]pyridin-3-yl-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(trifluoromethyl)anilino]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;N-[4-(trifluoromethyl)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine?

N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-imidazo[1,2-a]pyridin-3-yl-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(trifluoromethyl)anilino]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;N-[4-(trifluoromethyl)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine has a molecular weight of 2102.76 g/mol, XLogP of 26.32, 18 rotatable bonds, 5 hydrogen bond donors, and 27 hydrogen bond acceptors.

Where does this data come from?

All data for N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-imidazo[1,2-a]pyridin-3-yl-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethoxy)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;2-[4-(trifluoromethyl)anilino]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyridine-4-carbonitrile;N-[4-(trifluoromethyl)phenyl]-6-[2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine is sourced from PubChem (CID 158698219), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).