1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-[(1S,2S)-2-hydroxycyclopentyl]urea;(2S,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2S,3S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2R,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-methylurea;cis-(1S,2S)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;[(3R)-2-oxopyrrolidin-3-yl] N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]carbamate;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide

C259H252F6N62O20 — CID 158709114

IUPAC1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-[(1S,2S)-2-hydroxycyclopentyl]urea;(2S,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2S,3S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2R,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-methylurea;cis-(1S,2S)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;[(3R)-2-oxopyrrolidin-3-yl] N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]carbamate;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide
SMILESCCOc1ccccc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3C#N)ncc2c(N)n1.CCOc1ccccc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)n1.CNC(=O)Nc1cc2cc(-c3ccccc3C)nc(N)c2cn1.COCCN1CC[C@@]2(C[C@@H]2C(=O)Nc2cc3cc(-c4ccccc4C)nc(N)c3cn2)C1.COCCN1CC[C@@]2(C[C@H]2C(=O)Nc2cc3cc(-c4ccccc4C)nc(N)c3cn2)C1.COCCN1CC[C@]2(C[C@@H]2C(=O)Nc2cc3cc(-c4ccccc4C)nc(N)c3cn2)C1.Cc1ccccc1-c1cc2cc(NC(=O)N[C@H]3CCC[C@@H]3O)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(NC(=O)O[C@@H]3CCNC3=O)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cccnc3)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cccnc3)ncc2c(N)n1.N#C[C@@H]1C[C@H]1C(=O)Nc1cc2cc(-c3cc[nH]c3C(F)(F)F)nc(N)c2cn1.N#C[C@H]1C[C@@H]1C(=O)Nc1cc2cc(-c3cc[nH]c3C(F)(F)F)nc(N)c2cn1
InChIInChI=1S/3C25H29N5O2.2C24H21N5O.C21H23N5O2.2C21H19N5O2.C20H19N5O3.2C18H13F3N6O.C17H17N5O/c3*1-16-5-3-4-6-18(16)21-11-17-12-22(27-14-19(17)23(26)28-21)29-24(31)20-13-25(20)7-8-30(15-25)9-10-32-2;2*1-14-5-2-3-7-17(14)21-9-16-10-22(27-13-20(16)23(25)28-21)29-24(30)19-11-18(19)15-6-4-8-26-12-15;1-12-5-2-3-6-14(12)17-9-13-10-19(23-11-15(13)20(22)24-17)26-21(28)25-16-7-4-8-18(16)27;2*1-2-28-18-6-4-3-5-14(18)17-8-12-9-19(24-11-16(12)20(23)25-17)26-21(27)15-7-13(15)10-22;1-11-4-2-3-5-13(11)15-8-12-9-17(23-10-14(12)18(21)24-15)25-20(27)28-16-6-7-22-19(16)26;2*19-18(20,21)15-10(1-2-24-15)13-4-8-5-14(25-7-12(8)16(23)26-13)27-17(28)11-3-9(11)6-22;1-10-5-3-4-6-12(10)14-7-11-8-15(22-17(23)19-2)20-9-13(11)16(18)21-14/h3*3-6,11-12,14,20H,7-10,13,15H2,1-2H3,(H2,26,28)(H,27,29,31);2*2-10,12-13,18-19H,11H2,1H3,(H2,25,28)(H,27,29,30);2-3,5-6,9-11,16,18,27H,4,7-8H2,1H3,(H2,22,24)(H2,23,25,26,28);2*3-6,8-9,11,13,15H,2,7H2,1H3,(H2,23,25)(H,24,26,27);2-5,8-10,16H,6-7H2,1H3,(H2,21,24)(H,22,26)(H,23,25,27);2*1-2,4-5,7,9,11,24H,3H2,(H2,23,26)(H,25,27,28);3-9H,1-2H3,(H2,18,21)(H2,19,20,22,23)/t2*20-,25+;20-,25-;2*18-,19+;16-,18-;2*13-,15+;16-;2*9-,11+;/m10110010110./s1
InChIKeyIIMNHDPUXIQXRF-KZLBJZNVSA-N
MW4667.27 g/mol
LogP41.29
Rot. Bonds50

About 1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-[(1S,2S)-2-hydroxycyclopentyl]urea;(2S,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2S,3S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2R,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-methylurea;cis-(1S,2S)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;[(3R)-2-oxopyrrolidin-3-yl] N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]carbamate;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide

1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-[(1S,2S)-2-hydroxycyclopentyl]urea;(2S,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2S,3S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2R,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-methylurea;cis-(1S,2S)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;[(3R)-2-oxopyrrolidin-3-yl] N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]carbamate;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide (PubChem CID 158709114) has the molecular formula C259H252F6N62O20 and a molecular weight of 4667.27 g/mol. Its IUPAC name is 1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-[(1S,2S)-2-hydroxycyclopentyl]urea;(2S,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2S,3S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2R,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-methylurea;cis-(1S,2S)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;[(3R)-2-oxopyrrolidin-3-yl] N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]carbamate;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide.

Molecular Properties

Compound Name1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-[(1S,2S)-2-hydroxycyclopentyl]urea;(2S,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2S,3S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2R,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-methylurea;cis-(1S,2S)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;[(3R)-2-oxopyrrolidin-3-yl] N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]carbamate;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide
PubChem CID158709114
Molecular FormulaC259H252F6N62O20
Molecular Weight4667.27 g/mol
Exact Mass4664.05
IUPAC Name1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-[(1S,2S)-2-hydroxycyclopentyl]urea;(2S,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2S,3S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2R,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-methylurea;cis-(1S,2S)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;[(3R)-2-oxopyrrolidin-3-yl] N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]carbamate;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide
SMILESCCOc1ccccc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3C#N)ncc2c(N)n1.CCOc1ccccc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)n1.CNC(=O)Nc1cc2cc(-c3ccccc3C)nc(N)c2cn1.COCCN1CC[C@@]2(C[C@@H]2C(=O)Nc2cc3cc(-c4ccccc4C)nc(N)c3cn2)C1.COCCN1CC[C@@]2(C[C@H]2C(=O)Nc2cc3cc(-c4ccccc4C)nc(N)c3cn2)C1.COCCN1CC[C@]2(C[C@@H]2C(=O)Nc2cc3cc(-c4ccccc4C)nc(N)c3cn2)C1.Cc1ccccc1-c1cc2cc(NC(=O)N[C@H]3CCC[C@@H]3O)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(NC(=O)O[C@@H]3CCNC3=O)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cccnc3)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cccnc3)ncc2c(N)n1.N#C[C@@H]1C[C@H]1C(=O)Nc1cc2cc(-c3cc[nH]c3C(F)(F)F)nc(N)c2cn1.N#C[C@H]1C[C@@H]1C(=O)Nc1cc2cc(-c3cc[nH]c3C(F)(F)F)nc(N)c2cn1
InChIInChI=1S/3C25H29N5O2.2C24H21N5O.C21H23N5O2.2C21H19N5O2.C20H19N5O3.2C18H13F3N6O.C17H17N5O/c3*1-16-5-3-4-6-18(16)21-11-17-12-22(27-14-19(17)23(26)28-21)29-24(31)20-13-25(20)7-8-30(15-25)9-10-32-2;2*1-14-5-2-3-7-17(14)21-9-16-10-22(27-13-20(16)23(25)28-21)29-24(30)19-11-18(19)15-6-4-8-26-12-15;1-12-5-2-3-6-14(12)17-9-13-10-19(23-11-15(13)20(22)24-17)26-21(28)25-16-7-4-8-18(16)27;2*1-2-28-18-6-4-3-5-14(18)17-8-12-9-19(24-11-16(12)20(23)25-17)26-21(27)15-7-13(15)10-22;1-11-4-2-3-5-13(11)15-8-12-9-17(23-10-14(12)18(21)24-15)25-20(27)28-16-6-7-22-19(16)26;2*19-18(20,21)15-10(1-2-24-15)13-4-8-5-14(25-7-12(8)16(23)26-13)27-17(28)11-3-9(11)6-22;1-10-5-3-4-6-12(10)14-7-11-8-15(22-17(23)19-2)20-9-13(11)16(18)21-14/h3*3-6,11-12,14,20H,7-10,13,15H2,1-2H3,(H2,26,28)(H,27,29,31);2*2-10,12-13,18-19H,11H2,1H3,(H2,25,28)(H,27,29,30);2-3,5-6,9-11,16,18,27H,4,7-8H2,1H3,(H2,22,24)(H2,23,25,26,28);2*3-6,8-9,11,13,15H,2,7H2,1H3,(H2,23,25)(H,24,26,27);2-5,8-10,16H,6-7H2,1H3,(H2,21,24)(H,22,26)(H,23,25,27);2*1-2,4-5,7,9,11,24H,3H2,(H2,23,26)(H,25,27,28);3-9H,1-2H3,(H2,18,21)(H2,19,20,22,23)/t2*20-,25+;20-,25-;2*18-,19+;16-,18-;2*13-,15+;16-;2*9-,11+;/m10110010110./s1
InChIKeyIIMNHDPUXIQXRF-KZLBJZNVSA-N
XLogP41.29
TPSA1261.81 Ų
H-Bond Donors30
H-Bond Acceptors65
Rotatable Bonds50
Heavy Atoms347
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004667.27
LogP ≤ 541.29
H-Bond Donors ≤ 530
H-Bond Acceptors ≤ 1065

Analyze 1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-[(1S,2S)-2-hydroxycyclopentyl]urea;(2S,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2S,3S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2R,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-methylurea;cis-(1S,2S)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;[(3R)-2-oxopyrrolidin-3-yl] N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]carbamate;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of 1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-[(1S,2S)-2-hydroxycyclopentyl]urea;(2S,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2S,3S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2R,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-methylurea;cis-(1S,2S)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;[(3R)-2-oxopyrrolidin-3-yl] N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]carbamate;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide?
The IUPAC name of 1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-[(1S,2S)-2-hydroxycyclopentyl]urea;(2S,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2S,3S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2R,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-methylurea;cis-(1S,2S)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;[(3R)-2-oxopyrrolidin-3-yl] N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]carbamate;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide (CID 158709114) is 1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-[(1S,2S)-2-hydroxycyclopentyl]urea;(2S,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2S,3S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2R,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-methylurea;cis-(1S,2S)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;[(3R)-2-oxopyrrolidin-3-yl] N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]carbamate;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide.
What is the SMILES notation for 1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-[(1S,2S)-2-hydroxycyclopentyl]urea;(2S,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2S,3S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2R,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-methylurea;cis-(1S,2S)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;[(3R)-2-oxopyrrolidin-3-yl] N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]carbamate;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide?
The canonical SMILES for 1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-[(1S,2S)-2-hydroxycyclopentyl]urea;(2S,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2S,3S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2R,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-methylurea;cis-(1S,2S)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;[(3R)-2-oxopyrrolidin-3-yl] N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]carbamate;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide is CCOc1ccccc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3C#N)ncc2c(N)n1.CCOc1ccccc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)n1.CNC(=O)Nc1cc2cc(-c3ccccc3C)nc(N)c2cn1.COCCN1CC[C@@]2(C[C@@H]2C(=O)Nc2cc3cc(-c4ccccc4C)nc(N)c3cn2)C1.COCCN1CC[C@@]2(C[C@H]2C(=O)Nc2cc3cc(-c4ccccc4C)nc(N)c3cn2)C1.COCCN1CC[C@]2(C[C@@H]2C(=O)Nc2cc3cc(-c4ccccc4C)nc(N)c3cn2)C1.Cc1ccccc1-c1cc2cc(NC(=O)N[C@H]3CCC[C@@H]3O)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(NC(=O)O[C@@H]3CCNC3=O)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cccnc3)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3cccnc3)ncc2c(N)n1.N#C[C@@H]1C[C@H]1C(=O)Nc1cc2cc(-c3cc[nH]c3C(F)(F)F)nc(N)c2cn1.N#C[C@H]1C[C@@H]1C(=O)Nc1cc2cc(-c3cc[nH]c3C(F)(F)F)nc(N)c2cn1.
What is the InChIKey of 1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-[(1S,2S)-2-hydroxycyclopentyl]urea;(2S,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2S,3S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2R,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-methylurea;cis-(1S,2S)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;[(3R)-2-oxopyrrolidin-3-yl] N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]carbamate;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide?
The InChIKey is IIMNHDPUXIQXRF-KZLBJZNVSA-N. The full InChI is InChI=1S/3C25H29N5O2.2C24H21N5O.C21H23N5O2.2C21H19N5O2.C20H19N5O3.2C18H13F3N6O.C17H17N5O/c3*1-16-5-3-4-6-18(16)21-11-17-12-22(27-14-19(17)23(26)28-21)29-24(31)20-13-25(20)7-8-30(15-25)9-10-32-2;2*1-14-5-2-3-7-17(14)21-9-16-10-22(27-13-20(16)23(25)28-21)29-24(30)19-11-18(19)15-6-4-8-26-12-15;1-12-5-2-3-6-14(12)17-9-13-10-19(23-11-15(13)20(22)24-17)26-21(28)25-16-7-4-8-18(16)27;2*1-2-28-18-6-4-3-5-14(18)17-8-12-9-19(24-11-16(12)20(23)25-17)26-21(27)15-7-13(15)10-22;1-11-4-2-3-5-13(11)15-8-12-9-17(23-10-14(12)18(21)24-15)25-20(27)28-16-6-7-22-19(16)26;2*19-18(20,21)15-10(1-2-24-15)13-4-8-5-14(25-7-12(8)16(23)26-13)27-17(28)11-3-9(11)6-22;1-10-5-3-4-6-12(10)14-7-11-8-15(22-17(23)19-2)20-9-13(11)16(18)21-14/h3*3-6,11-12,14,20H,7-10,13,15H2,1-2H3,(H2,26,28)(H,27,29,31);2*2-10,12-13,18-19H,11H2,1H3,(H2,25,28)(H,27,29,30);2-3,5-6,9-11,16,18,27H,4,7-8H2,1H3,(H2,22,24)(H2,23,25,26,28);2*3-6,8-9,11,13,15H,2,7H2,1H3,(H2,23,25)(H,24,26,27);2-5,8-10,16H,6-7H2,1H3,(H2,21,24)(H,22,26)(H,23,25,27);2*1-2,4-5,7,9,11,24H,3H2,(H2,23,26)(H,25,27,28);3-9H,1-2H3,(H2,18,21)(H2,19,20,22,23)/t2*20-,25+;20-,25-;2*18-,19+;16-,18-;2*13-,15+;16-;2*9-,11+;/m10110010110./s1.
What are the key properties of 1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-[(1S,2S)-2-hydroxycyclopentyl]urea;(2S,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2S,3S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2R,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-methylurea;cis-(1S,2S)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;[(3R)-2-oxopyrrolidin-3-yl] N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]carbamate;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide?
1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-[(1S,2S)-2-hydroxycyclopentyl]urea;(2S,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2S,3S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2R,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-methylurea;cis-(1S,2S)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;[(3R)-2-oxopyrrolidin-3-yl] N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]carbamate;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide has a molecular weight of 4667.27 g/mol, XLogP of 41.29, 50 rotatable bonds, 30 hydrogen bond donors, and 65 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-[(1S,2S)-2-hydroxycyclopentyl]urea;(2S,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2S,3S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;(2R,3R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-5-(2-methoxyethyl)-5-azaspiro[2.4]heptane-2-carboxamide;1-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-3-methylurea;cis-(1S,2S)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2-ethoxyphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-(trifluoromethyl)-1H-pyrrol-3-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;[(3R)-2-oxopyrrolidin-3-yl] N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]carbamate;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyridin-3-ylcyclopropane-1-carboxamide is sourced from PubChem (CID 158709114), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).