8-(6-chloro-1H-indazol-4-yl)-3-(cyclohexylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(cyclopropylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(2-methylpropyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;6-(difluoromethyl)-4-(4-methylsulfonylpiperazin-1-yl)-1H-indole

C71H85Cl3F2N18O8S — CID 158711894

About 8-(6-chloro-1H-indazol-4-yl)-3-(cyclohexylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(cyclopropylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(2-methylpropyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;6-(difluoromethyl)-4-(4-methylsulfonylpiperazin-1-yl)-1H-indole

8-(6-chloro-1H-indazol-4-yl)-3-(cyclohexylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(cyclopropylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(2-methylpropyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;6-(difluoromethyl)-4-(4-methylsulfonylpiperazin-1-yl)-1H-indole (PubChem CID 158711894) has the molecular formula C71H85Cl3F2N18O8S and a molecular weight of 1495.00 g/mol. Its IUPAC name is 8-(6-chloro-1H-indazol-4-yl)-3-(cyclohexylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(cyclopropylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(2-methylpropyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;6-(difluoromethyl)-4-(4-methylsulfonylpiperazin-1-yl)-1H-indole.

Molecular Properties

• Compound Name: 8-(6-chloro-1H-indazol-4-yl)-3-(cyclohexylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(cyclopropylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(2-methylpropyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;6-(difluoromethyl)-4-(4-methylsulfonylpiperazin-1-yl)-1H-indole
• PubChem CID: 158711894
• Molecular Formula: C71H85Cl3F2N18O8S
• Molecular Weight: 1495.00 g/mol
• Exact Mass: 1492.56
• IUPAC Name: 8-(6-chloro-1H-indazol-4-yl)-3-(cyclohexylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(cyclopropylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(2-methylpropyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;6-(difluoromethyl)-4-(4-methylsulfonylpiperazin-1-yl)-1H-indole
• SMILES: CC(C)CN1C(=O)NC2(CCN(c3cc(Cl)cc4[nH]ncc34)CC2)C1=O.CS(=O)(=O)N1CCN(c2cc(C(F)F)cc3[nH]ccc23)CC1.O=C1NC2(CCN(c3cc(Cl)cc4[nH]ncc34)CC2)C(=O)N1CC1CC1.O=C1NC2(CCN(c3cc(Cl)cc4[nH]ncc34)CC2)C(=O)N1CC1CCCCC1
• InChI: InChI=1S/C21H26ClN5O2.C18H20ClN5O2.C18H22ClN5O2.C14H17F2N3O2S/c22-15-10-17-16(12-23-25-17)18(11-15)26-8-6-21(7-9-26)19(28)27(20(29)24-21)13-14-4-2-1-3-5-14;19-12-7-14-13(9-20-22-14)15(8-12)23-5-3-18(4-6-23)16(25)24(17(26)21-18)10-11-1-2-11;1-11(2)10-24-16(25)18(21-17(24)26)3-5-23(6-4-18)15-8-12(19)7-14-13(15)9-20-22-14;1-22(20,21)19-6-4-18(5-7-19)13-9-10(14(15)16)8-12-11(13)2-3-17-12/h10-12,14H,1-9,13H2,(H,23,25)(H,24,29);7-9,11H,1-6,10H2,(H,20,22)(H,21,26);7-9,11H,3-6,10H2,1-2H3,(H,20,22)(H,21,26);2-3,8-9,14,17H,4-7H2,1H3
• InChIKey: IIVDFTGFOAKYBO-UHFFFAOYSA-N
• XLogP: 11.15
• TPSA: 300.40 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 15
• Rotatable Bonds: 12
• Heavy Atoms: 103
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1495.00
LogP ≤ 5	11.15
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	15

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydantoin', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 8-(6-chloro-1H-indazol-4-yl)-3-(cyclohexylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(cyclopropylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(2-methylpropyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;6-(difluoromethyl)-4-(4-methylsulfonylpiperazin-1-yl)-1H-indole?

The IUPAC name of 8-(6-chloro-1H-indazol-4-yl)-3-(cyclohexylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(cyclopropylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(2-methylpropyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;6-(difluoromethyl)-4-(4-methylsulfonylpiperazin-1-yl)-1H-indole (CID 158711894) is 8-(6-chloro-1H-indazol-4-yl)-3-(cyclohexylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(cyclopropylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(2-methylpropyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;6-(difluoromethyl)-4-(4-methylsulfonylpiperazin-1-yl)-1H-indole.

What is the SMILES notation for 8-(6-chloro-1H-indazol-4-yl)-3-(cyclohexylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(cyclopropylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(2-methylpropyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;6-(difluoromethyl)-4-(4-methylsulfonylpiperazin-1-yl)-1H-indole?

The canonical SMILES for 8-(6-chloro-1H-indazol-4-yl)-3-(cyclohexylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(cyclopropylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(2-methylpropyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;6-(difluoromethyl)-4-(4-methylsulfonylpiperazin-1-yl)-1H-indole is CC(C)CN1C(=O)NC2(CCN(c3cc(Cl)cc4[nH]ncc34)CC2)C1=O.CS(=O)(=O)N1CCN(c2cc(C(F)F)cc3[nH]ccc23)CC1.O=C1NC2(CCN(c3cc(Cl)cc4[nH]ncc34)CC2)C(=O)N1CC1CC1.O=C1NC2(CCN(c3cc(Cl)cc4[nH]ncc34)CC2)C(=O)N1CC1CCCCC1.

What is the InChIKey of 8-(6-chloro-1H-indazol-4-yl)-3-(cyclohexylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(cyclopropylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(2-methylpropyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;6-(difluoromethyl)-4-(4-methylsulfonylpiperazin-1-yl)-1H-indole?

The InChIKey is IIVDFTGFOAKYBO-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H26ClN5O2.C18H20ClN5O2.C18H22ClN5O2.C14H17F2N3O2S/c22-15-10-17-16(12-23-25-17)18(11-15)26-8-6-21(7-9-26)19(28)27(20(29)24-21)13-14-4-2-1-3-5-14;19-12-7-14-13(9-20-22-14)15(8-12)23-5-3-18(4-6-23)16(25)24(17(26)21-18)10-11-1-2-11;1-11(2)10-24-16(25)18(21-17(24)26)3-5-23(6-4-18)15-8-12(19)7-14-13(15)9-20-22-14;1-22(20,21)19-6-4-18(5-7-19)13-9-10(14(15)16)8-12-11(13)2-3-17-12/h10-12,14H,1-9,13H2,(H,23,25)(H,24,29);7-9,11H,1-6,10H2,(H,20,22)(H,21,26);7-9,11H,3-6,10H2,1-2H3,(H,20,22)(H,21,26);2-3,8-9,14,17H,4-7H2,1H3.

What are the key properties of 8-(6-chloro-1H-indazol-4-yl)-3-(cyclohexylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(cyclopropylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(2-methylpropyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;6-(difluoromethyl)-4-(4-methylsulfonylpiperazin-1-yl)-1H-indole?

8-(6-chloro-1H-indazol-4-yl)-3-(cyclohexylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(cyclopropylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(2-methylpropyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;6-(difluoromethyl)-4-(4-methylsulfonylpiperazin-1-yl)-1H-indole has a molecular weight of 1495.00 g/mol, XLogP of 11.15, 12 rotatable bonds, 7 hydrogen bond donors, and 15 hydrogen bond acceptors.

Where does this data come from?

All data for 8-(6-chloro-1H-indazol-4-yl)-3-(cyclohexylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(cyclopropylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-(6-chloro-1H-indazol-4-yl)-3-(2-methylpropyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione;6-(difluoromethyl)-4-(4-methylsulfonylpiperazin-1-yl)-1H-indole is sourced from PubChem (CID 158711894), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).