(5R)-5-[4-[2,8-bis(trifluoromethyl)quinolin-4-yl]phenyl]-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;5-[[5-(3-cyclopropylprop-2-ynoxy)-3-oxo-1H-isoindol-2-yl]methyl]-5-(4-fluorophenyl)imidazolidine-2,4-dione;(5R)-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(2-oxo-1H-quinolin-4-yl)phenyl]imidazolidine-2,4-dione;5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-pyridin-3-ylimidazolidine-2,4-dione;(5R)-5-(4-fluorophenyl)-5-[[3-oxo-5-(3-quinolin-3-ylprop-2-ynoxy)-1H-isoindol-2-yl]methyl]imidazolidine-2,4-dione

C127H90F11N19O18 — CID 158711967

About (5R)-5-[4-[2,8-bis(trifluoromethyl)quinolin-4-yl]phenyl]-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;5-[[5-(3-cyclopropylprop-2-ynoxy)-3-oxo-1H-isoindol-2-yl]methyl]-5-(4-fluorophenyl)imidazolidine-2,4-dione;(5R)-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(2-oxo-1H-quinolin-4-yl)phenyl]imidazolidine-2,4-dione;5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-pyridin-3-ylimidazolidine-2,4-dione;(5R)-5-(4-fluorophenyl)-5-[[3-oxo-5-(3-quinolin-3-ylprop-2-ynoxy)-1H-isoindol-2-yl]methyl]imidazolidine-2,4-dione

(5R)-5-[4-[2,8-bis(trifluoromethyl)quinolin-4-yl]phenyl]-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;5-[[5-(3-cyclopropylprop-2-ynoxy)-3-oxo-1H-isoindol-2-yl]methyl]-5-(4-fluorophenyl)imidazolidine-2,4-dione;(5R)-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(2-oxo-1H-quinolin-4-yl)phenyl]imidazolidine-2,4-dione;5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-pyridin-3-ylimidazolidine-2,4-dione;(5R)-5-(4-fluorophenyl)-5-[[3-oxo-5-(3-quinolin-3-ylprop-2-ynoxy)-1H-isoindol-2-yl]methyl]imidazolidine-2,4-dione (PubChem CID 158711967) has the molecular formula C127H90F11N19O18 and a molecular weight of 2379.21 g/mol. Its IUPAC name is (5R)-5-[4-[2,8-bis(trifluoromethyl)quinolin-4-yl]phenyl]-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;5-[[5-(3-cyclopropylprop-2-ynoxy)-3-oxo-1H-isoindol-2-yl]methyl]-5-(4-fluorophenyl)imidazolidine-2,4-dione;(5R)-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(2-oxo-1H-quinolin-4-yl)phenyl]imidazolidine-2,4-dione;5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-pyridin-3-ylimidazolidine-2,4-dione;(5R)-5-(4-fluorophenyl)-5-[[3-oxo-5-(3-quinolin-3-ylprop-2-ynoxy)-1H-isoindol-2-yl]methyl]imidazolidine-2,4-dione.

Molecular Properties

• Compound Name: (5R)-5-[4-[2,8-bis(trifluoromethyl)quinolin-4-yl]phenyl]-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;5-[[5-(3-cyclopropylprop-2-ynoxy)-3-oxo-1H-isoindol-2-yl]methyl]-5-(4-fluorophenyl)imidazolidine-2,4-dione;(5R)-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(2-oxo-1H-quinolin-4-yl)phenyl]imidazolidine-2,4-dione;5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-pyridin-3-ylimidazolidine-2,4-dione;(5R)-5-(4-fluorophenyl)-5-[[3-oxo-5-(3-quinolin-3-ylprop-2-ynoxy)-1H-isoindol-2-yl]methyl]imidazolidine-2,4-dione
• PubChem CID: 158711967
• Molecular Formula: C127H90F11N19O18
• Molecular Weight: 2379.21 g/mol
• Exact Mass: 2377.65
• IUPAC Name: (5R)-5-[4-[2,8-bis(trifluoromethyl)quinolin-4-yl]phenyl]-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;5-[[5-(3-cyclopropylprop-2-ynoxy)-3-oxo-1H-isoindol-2-yl]methyl]-5-(4-fluorophenyl)imidazolidine-2,4-dione;(5R)-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(2-oxo-1H-quinolin-4-yl)phenyl]imidazolidine-2,4-dione;5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-pyridin-3-ylimidazolidine-2,4-dione;(5R)-5-(4-fluorophenyl)-5-[[3-oxo-5-(3-quinolin-3-ylprop-2-ynoxy)-1H-isoindol-2-yl]methyl]imidazolidine-2,4-dione
• SMILES: O=C1NC(=O)C(CN2Cc3ccc(F)cc3C2=O)(c2cccnc2)N1.O=C1NC(=O)C(CN2Cc3ccc(OCC#CC4CC4)cc3C2=O)(c2ccc(F)cc2)N1.O=C1NC(=O)[C@](CN2Cc3ccc(F)cc3C2=O)(c2ccc(-c3cc(=O)[nH]c4ccccc34)cc2)N1.O=C1NC(=O)[C@](CN2Cc3ccc(F)cc3C2=O)(c2ccc(-c3cc(C(F)(F)F)nc4c(C(F)(F)F)cccc34)cc2)N1.O=C1NC(=O)[C@](CN2Cc3ccc(OCC#Cc4cnc5ccccc5c4)cc3C2=O)(c2ccc(F)cc2)N1
• InChI: InChI=1S/C30H21FN4O4.C29H17F7N4O3.C27H19FN4O4.C24H20FN3O4.C17H13FN4O3/c31-23-10-8-22(9-11-23)30(28(37)33-29(38)34-30)18-35-17-21-7-12-24(15-25(21)27(35)36)39-13-3-4-19-14-20-5-1-2-6-26(20)32-16-19;30-17-9-6-15-12-40(24(41)20(15)10-17)13-27(25(42)38-26(43)39-27)16-7-4-14(5-8-16)19-11-22(29(34,35)36)37-23-18(19)2-1-3-21(23)28(31,32)33;28-18-10-7-16-13-32(24(34)21(16)11-18)14-27(25(35)30-26(36)31-27)17-8-5-15(6-9-17)20-12-23(33)29-22-4-2-1-3-19(20)22;25-18-8-6-17(7-9-18)24(22(30)26-23(31)27-24)14-28-13-16-5-10-19(12-20(16)21(28)29)32-11-1-2-15-3-4-15;18-12-4-3-10-8-22(14(23)13(10)6-12)9-17(11-2-1-5-19-7-11)15(24)20-16(25)21-17/h1-2,5-12,14-16H,13,17-18H2,(H2,33,34,37,38);1-11H,12-13H2,(H2,38,39,42,43);1-12H,13-14H2,(H,29,33)(H2,30,31,35,36);5-10,12,15H,3-4,11,13-14H2,(H2,26,27,30,31);1-7H,8-9H2,(H2,20,21,24,25)/t30-;2*27-;;/m000../s1
• InChIKey: IIVLVZFNQWXRQZ-ATXQWBSASA-N
• XLogP: 15.51
• TPSA: 482.54 Ų
• H-Bond Donors: 11
• H-Bond Acceptors: 21
• Rotatable Bonds: 21
• Heavy Atoms: 175
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2379.21
LogP ≤ 5	15.51
H-Bond Donors ≤ 5	11
H-Bond Acceptors ≤ 10	21

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydantoin', 'substructure': 'N/A'}, {'alert_name': 'triple_bond', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of (5R)-5-[4-[2,8-bis(trifluoromethyl)quinolin-4-yl]phenyl]-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;5-[[5-(3-cyclopropylprop-2-ynoxy)-3-oxo-1H-isoindol-2-yl]methyl]-5-(4-fluorophenyl)imidazolidine-2,4-dione;(5R)-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(2-oxo-1H-quinolin-4-yl)phenyl]imidazolidine-2,4-dione;5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-pyridin-3-ylimidazolidine-2,4-dione;(5R)-5-(4-fluorophenyl)-5-[[3-oxo-5-(3-quinolin-3-ylprop-2-ynoxy)-1H-isoindol-2-yl]methyl]imidazolidine-2,4-dione?

The IUPAC name of (5R)-5-[4-[2,8-bis(trifluoromethyl)quinolin-4-yl]phenyl]-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;5-[[5-(3-cyclopropylprop-2-ynoxy)-3-oxo-1H-isoindol-2-yl]methyl]-5-(4-fluorophenyl)imidazolidine-2,4-dione;(5R)-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(2-oxo-1H-quinolin-4-yl)phenyl]imidazolidine-2,4-dione;5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-pyridin-3-ylimidazolidine-2,4-dione;(5R)-5-(4-fluorophenyl)-5-[[3-oxo-5-(3-quinolin-3-ylprop-2-ynoxy)-1H-isoindol-2-yl]methyl]imidazolidine-2,4-dione (CID 158711967) is (5R)-5-[4-[2,8-bis(trifluoromethyl)quinolin-4-yl]phenyl]-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;5-[[5-(3-cyclopropylprop-2-ynoxy)-3-oxo-1H-isoindol-2-yl]methyl]-5-(4-fluorophenyl)imidazolidine-2,4-dione;(5R)-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(2-oxo-1H-quinolin-4-yl)phenyl]imidazolidine-2,4-dione;5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-pyridin-3-ylimidazolidine-2,4-dione;(5R)-5-(4-fluorophenyl)-5-[[3-oxo-5-(3-quinolin-3-ylprop-2-ynoxy)-1H-isoindol-2-yl]methyl]imidazolidine-2,4-dione.

What is the SMILES notation for (5R)-5-[4-[2,8-bis(trifluoromethyl)quinolin-4-yl]phenyl]-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;5-[[5-(3-cyclopropylprop-2-ynoxy)-3-oxo-1H-isoindol-2-yl]methyl]-5-(4-fluorophenyl)imidazolidine-2,4-dione;(5R)-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(2-oxo-1H-quinolin-4-yl)phenyl]imidazolidine-2,4-dione;5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-pyridin-3-ylimidazolidine-2,4-dione;(5R)-5-(4-fluorophenyl)-5-[[3-oxo-5-(3-quinolin-3-ylprop-2-ynoxy)-1H-isoindol-2-yl]methyl]imidazolidine-2,4-dione?

The canonical SMILES for (5R)-5-[4-[2,8-bis(trifluoromethyl)quinolin-4-yl]phenyl]-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;5-[[5-(3-cyclopropylprop-2-ynoxy)-3-oxo-1H-isoindol-2-yl]methyl]-5-(4-fluorophenyl)imidazolidine-2,4-dione;(5R)-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(2-oxo-1H-quinolin-4-yl)phenyl]imidazolidine-2,4-dione;5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-pyridin-3-ylimidazolidine-2,4-dione;(5R)-5-(4-fluorophenyl)-5-[[3-oxo-5-(3-quinolin-3-ylprop-2-ynoxy)-1H-isoindol-2-yl]methyl]imidazolidine-2,4-dione is O=C1NC(=O)C(CN2Cc3ccc(F)cc3C2=O)(c2cccnc2)N1.O=C1NC(=O)C(CN2Cc3ccc(OCC#CC4CC4)cc3C2=O)(c2ccc(F)cc2)N1.O=C1NC(=O)[C@](CN2Cc3ccc(F)cc3C2=O)(c2ccc(-c3cc(=O)[nH]c4ccccc34)cc2)N1.O=C1NC(=O)[C@](CN2Cc3ccc(F)cc3C2=O)(c2ccc(-c3cc(C(F)(F)F)nc4c(C(F)(F)F)cccc34)cc2)N1.O=C1NC(=O)[C@](CN2Cc3ccc(OCC#Cc4cnc5ccccc5c4)cc3C2=O)(c2ccc(F)cc2)N1.

What is the InChIKey of (5R)-5-[4-[2,8-bis(trifluoromethyl)quinolin-4-yl]phenyl]-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;5-[[5-(3-cyclopropylprop-2-ynoxy)-3-oxo-1H-isoindol-2-yl]methyl]-5-(4-fluorophenyl)imidazolidine-2,4-dione;(5R)-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(2-oxo-1H-quinolin-4-yl)phenyl]imidazolidine-2,4-dione;5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-pyridin-3-ylimidazolidine-2,4-dione;(5R)-5-(4-fluorophenyl)-5-[[3-oxo-5-(3-quinolin-3-ylprop-2-ynoxy)-1H-isoindol-2-yl]methyl]imidazolidine-2,4-dione?

The InChIKey is IIVLVZFNQWXRQZ-ATXQWBSASA-N. The full InChI is InChI=1S/C30H21FN4O4.C29H17F7N4O3.C27H19FN4O4.C24H20FN3O4.C17H13FN4O3/c31-23-10-8-22(9-11-23)30(28(37)33-29(38)34-30)18-35-17-21-7-12-24(15-25(21)27(35)36)39-13-3-4-19-14-20-5-1-2-6-26(20)32-16-19;30-17-9-6-15-12-40(24(41)20(15)10-17)13-27(25(42)38-26(43)39-27)16-7-4-14(5-8-16)19-11-22(29(34,35)36)37-23-18(19)2-1-3-21(23)28(31,32)33;28-18-10-7-16-13-32(24(34)21(16)11-18)14-27(25(35)30-26(36)31-27)17-8-5-15(6-9-17)20-12-23(33)29-22-4-2-1-3-19(20)22;25-18-8-6-17(7-9-18)24(22(30)26-23(31)27-24)14-28-13-16-5-10-19(12-20(16)21(28)29)32-11-1-2-15-3-4-15;18-12-4-3-10-8-22(14(23)13(10)6-12)9-17(11-2-1-5-19-7-11)15(24)20-16(25)21-17/h1-2,5-12,14-16H,13,17-18H2,(H2,33,34,37,38);1-11H,12-13H2,(H2,38,39,42,43);1-12H,13-14H2,(H,29,33)(H2,30,31,35,36);5-10,12,15H,3-4,11,13-14H2,(H2,26,27,30,31);1-7H,8-9H2,(H2,20,21,24,25)/t30-;2*27-;;/m000../s1.

What are the key properties of (5R)-5-[4-[2,8-bis(trifluoromethyl)quinolin-4-yl]phenyl]-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;5-[[5-(3-cyclopropylprop-2-ynoxy)-3-oxo-1H-isoindol-2-yl]methyl]-5-(4-fluorophenyl)imidazolidine-2,4-dione;(5R)-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(2-oxo-1H-quinolin-4-yl)phenyl]imidazolidine-2,4-dione;5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-pyridin-3-ylimidazolidine-2,4-dione;(5R)-5-(4-fluorophenyl)-5-[[3-oxo-5-(3-quinolin-3-ylprop-2-ynoxy)-1H-isoindol-2-yl]methyl]imidazolidine-2,4-dione?

(5R)-5-[4-[2,8-bis(trifluoromethyl)quinolin-4-yl]phenyl]-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;5-[[5-(3-cyclopropylprop-2-ynoxy)-3-oxo-1H-isoindol-2-yl]methyl]-5-(4-fluorophenyl)imidazolidine-2,4-dione;(5R)-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(2-oxo-1H-quinolin-4-yl)phenyl]imidazolidine-2,4-dione;5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-pyridin-3-ylimidazolidine-2,4-dione;(5R)-5-(4-fluorophenyl)-5-[[3-oxo-5-(3-quinolin-3-ylprop-2-ynoxy)-1H-isoindol-2-yl]methyl]imidazolidine-2,4-dione has a molecular weight of 2379.21 g/mol, XLogP of 15.51, 21 rotatable bonds, 11 hydrogen bond donors, and 21 hydrogen bond acceptors.

Where does this data come from?

All data for (5R)-5-[4-[2,8-bis(trifluoromethyl)quinolin-4-yl]phenyl]-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;5-[[5-(3-cyclopropylprop-2-ynoxy)-3-oxo-1H-isoindol-2-yl]methyl]-5-(4-fluorophenyl)imidazolidine-2,4-dione;(5R)-5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-[4-(2-oxo-1H-quinolin-4-yl)phenyl]imidazolidine-2,4-dione;5-[(5-fluoro-3-oxo-1H-isoindol-2-yl)methyl]-5-pyridin-3-ylimidazolidine-2,4-dione;(5R)-5-(4-fluorophenyl)-5-[[3-oxo-5-(3-quinolin-3-ylprop-2-ynoxy)-1H-isoindol-2-yl]methyl]imidazolidine-2,4-dione is sourced from PubChem (CID 158711967), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).