N-[(3,5-difluorophenyl)methyl]-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;2,5-dihydropyrrol-1-yl-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;N-(2-ethylsulfanylethyl)-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(2-pyridin-3-ylethyl)thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(thiophen-2-ylmethyl)thiophene-2-carboxamide

C77H67F17N16O5S7 — CID 158734072

IUPACN-[(3,5-difluorophenyl)methyl]-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;2,5-dihydropyrrol-1-yl-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;N-(2-ethylsulfanylethyl)-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(2-pyridin-3-ylethyl)thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(thiophen-2-ylmethyl)thiophene-2-carboxamide
SMILESCCSCCNC(=O)c1ccc(-c2cc(C(F)(F)F)n(C)n2)s1.Cn1nc(-c2ccc(C(=O)N3CC=CC3)s2)cc1C(F)(F)F.Cn1nc(-c2ccc(C(=O)NCCc3cccnc3)s2)cc1C(F)(F)F.Cn1nc(-c2ccc(C(=O)NCc3cc(F)cc(F)c3)s2)cc1C(F)(F)F.Cn1nc(-c2ccc(C(=O)NCc3cccs3)s2)cc1C(F)(F)F
InChIInChI=1S/C17H12F5N3OS.C17H15F3N4OS.C15H12F3N3OS2.C14H16F3N3OS2.C14H12F3N3OS/c1-25-15(17(20,21)22)7-12(24-25)13-2-3-14(27-13)16(26)23-8-9-4-10(18)6-11(19)5-9;1-24-15(17(18,19)20)9-12(23-24)13-4-5-14(26-13)16(25)22-8-6-11-3-2-7-21-10-11;1-21-13(15(16,17)18)7-10(20-21)11-4-5-12(24-11)14(22)19-8-9-3-2-6-23-9;1-3-22-7-6-18-13(21)11-5-4-10(23-11)9-8-12(14(15,16)17)20(2)19-9;1-19-12(14(15,16)17)8-9(18-19)10-4-5-11(22-10)13(21)20-6-2-3-7-20/h2-7H,8H2,1H3,(H,23,26);2-5,7,9-10H,6,8H2,1H3,(H,22,25);2-7H,8H2,1H3,(H,19,22);4-5,8H,3,6-7H2,1-2H3,(H,18,21);2-5,8H,6-7H2,1H3
InChIKeyILLKCVPCGBZCCE-UHFFFAOYSA-N
MW1843.92 g/mol
LogP18.90
Rot. Bonds21

About N-[(3,5-difluorophenyl)methyl]-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;2,5-dihydropyrrol-1-yl-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;N-(2-ethylsulfanylethyl)-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(2-pyridin-3-ylethyl)thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(thiophen-2-ylmethyl)thiophene-2-carboxamide

N-[(3,5-difluorophenyl)methyl]-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;2,5-dihydropyrrol-1-yl-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;N-(2-ethylsulfanylethyl)-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(2-pyridin-3-ylethyl)thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(thiophen-2-ylmethyl)thiophene-2-carboxamide (PubChem CID 158734072) has the molecular formula C77H67F17N16O5S7 and a molecular weight of 1843.92 g/mol. Its IUPAC name is N-[(3,5-difluorophenyl)methyl]-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;2,5-dihydropyrrol-1-yl-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;N-(2-ethylsulfanylethyl)-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(2-pyridin-3-ylethyl)thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(thiophen-2-ylmethyl)thiophene-2-carboxamide.

Molecular Properties

Compound NameN-[(3,5-difluorophenyl)methyl]-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;2,5-dihydropyrrol-1-yl-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;N-(2-ethylsulfanylethyl)-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(2-pyridin-3-ylethyl)thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(thiophen-2-ylmethyl)thiophene-2-carboxamide
PubChem CID158734072
Molecular FormulaC77H67F17N16O5S7
Molecular Weight1843.92 g/mol
Exact Mass1842.33
IUPAC NameN-[(3,5-difluorophenyl)methyl]-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;2,5-dihydropyrrol-1-yl-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;N-(2-ethylsulfanylethyl)-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(2-pyridin-3-ylethyl)thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(thiophen-2-ylmethyl)thiophene-2-carboxamide
SMILESCCSCCNC(=O)c1ccc(-c2cc(C(F)(F)F)n(C)n2)s1.Cn1nc(-c2ccc(C(=O)N3CC=CC3)s2)cc1C(F)(F)F.Cn1nc(-c2ccc(C(=O)NCCc3cccnc3)s2)cc1C(F)(F)F.Cn1nc(-c2ccc(C(=O)NCc3cc(F)cc(F)c3)s2)cc1C(F)(F)F.Cn1nc(-c2ccc(C(=O)NCc3cccs3)s2)cc1C(F)(F)F
InChIInChI=1S/C17H12F5N3OS.C17H15F3N4OS.C15H12F3N3OS2.C14H16F3N3OS2.C14H12F3N3OS/c1-25-15(17(20,21)22)7-12(24-25)13-2-3-14(27-13)16(26)23-8-9-4-10(18)6-11(19)5-9;1-24-15(17(18,19)20)9-12(23-24)13-4-5-14(26-13)16(25)22-8-6-11-3-2-7-21-10-11;1-21-13(15(16,17)18)7-10(20-21)11-4-5-12(24-11)14(22)19-8-9-3-2-6-23-9;1-3-22-7-6-18-13(21)11-5-4-10(23-11)9-8-12(14(15,16)17)20(2)19-9;1-19-12(14(15,16)17)8-9(18-19)10-4-5-11(22-10)13(21)20-6-2-3-7-20/h2-7H,8H2,1H3,(H,23,26);2-5,7,9-10H,6,8H2,1H3,(H,22,25);2-7H,8H2,1H3,(H,19,22);4-5,8H,3,6-7H2,1-2H3,(H,18,21);2-5,8H,6-7H2,1H3
InChIKeyILLKCVPCGBZCCE-UHFFFAOYSA-N
XLogP18.90
TPSA238.70 Ų
H-Bond Donors4
H-Bond Acceptors23
Rotatable Bonds21
Heavy Atoms122
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001843.92
LogP ≤ 518.90
H-Bond Donors ≤ 54
H-Bond Acceptors ≤ 1023

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}, {'alert_name': 'isolated_alkene', 'substructure': 'N/A'}

Analyze N-[(3,5-difluorophenyl)methyl]-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;2,5-dihydropyrrol-1-yl-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;N-(2-ethylsulfanylethyl)-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(2-pyridin-3-ylethyl)thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(thiophen-2-ylmethyl)thiophene-2-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-(3,5-difluoro-4-pyridinyl)-5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]thiophene-2-carboxamide
CID 68062356
5-[3-(2-fluorophenyl)-1-methylpyrazol-5-yl]-N-(3-fluoro-4-pyridinyl)thiophene-2-carboxamide
CID 68062358
N-(3,5-difluoro-4-pyridinyl)-5-(1-methyl-3-phenylpyrazol-5-yl)thiophene-2-carboxamide
CID 68062363
N-(3-fluoro-4-pyridinyl)-5-(1-methyl-3-phenylpyrazol-5-yl)thiophene-2-carboxamide
CID 68062365
5-pyridin-2-yl-N-[4-[5-thiophen-2-yl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]thiophene-2-carboxamide
CID 2811542
3-(4-fluorophenyl)-1-methyl-N-{[5-(thiophen-2-yl)pyridin-3-yl]methyl}-1H-pyrazole-5-carboxamide
CID 91630614
5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(2-pyridin-3-ylethyl)thiophene-2-carboxamide
CID 23627578
5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(pyridin-4-ylmethyl)thiophene-2-carboxamide
CID 23627971
5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(pyridin-3-ylmethyl)thiophene-2-carboxamide
CID 23628100
5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(1-pyridin-4-ylpropyl)thiophene-2-carboxamide
CID 67089205
3-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(pyridin-4-ylmethyl)thiophene-2-carboxamide
CID 122698828
2-fluoro-5-[5-[3-[3-[(5-fluoropyridine-3-carbonyl)amino]propylcarbamoyl]-1H-pyrazol-5-yl]thiophen-3-yl]-N-[3-[(3-phenyl-1H-pyrazole-5-carbonyl)amino]propyl]pyridine-3-carboxamide
CID 131991827

Frequently Asked Questions

What is the IUPAC name of N-[(3,5-difluorophenyl)methyl]-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;2,5-dihydropyrrol-1-yl-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;N-(2-ethylsulfanylethyl)-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(2-pyridin-3-ylethyl)thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(thiophen-2-ylmethyl)thiophene-2-carboxamide?
The IUPAC name of N-[(3,5-difluorophenyl)methyl]-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;2,5-dihydropyrrol-1-yl-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;N-(2-ethylsulfanylethyl)-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(2-pyridin-3-ylethyl)thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(thiophen-2-ylmethyl)thiophene-2-carboxamide (CID 158734072) is N-[(3,5-difluorophenyl)methyl]-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;2,5-dihydropyrrol-1-yl-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;N-(2-ethylsulfanylethyl)-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(2-pyridin-3-ylethyl)thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(thiophen-2-ylmethyl)thiophene-2-carboxamide.
What is the SMILES notation for N-[(3,5-difluorophenyl)methyl]-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;2,5-dihydropyrrol-1-yl-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;N-(2-ethylsulfanylethyl)-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(2-pyridin-3-ylethyl)thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(thiophen-2-ylmethyl)thiophene-2-carboxamide?
The canonical SMILES for N-[(3,5-difluorophenyl)methyl]-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;2,5-dihydropyrrol-1-yl-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;N-(2-ethylsulfanylethyl)-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(2-pyridin-3-ylethyl)thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(thiophen-2-ylmethyl)thiophene-2-carboxamide is CCSCCNC(=O)c1ccc(-c2cc(C(F)(F)F)n(C)n2)s1.Cn1nc(-c2ccc(C(=O)N3CC=CC3)s2)cc1C(F)(F)F.Cn1nc(-c2ccc(C(=O)NCCc3cccnc3)s2)cc1C(F)(F)F.Cn1nc(-c2ccc(C(=O)NCc3cc(F)cc(F)c3)s2)cc1C(F)(F)F.Cn1nc(-c2ccc(C(=O)NCc3cccs3)s2)cc1C(F)(F)F.
What is the InChIKey of N-[(3,5-difluorophenyl)methyl]-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;2,5-dihydropyrrol-1-yl-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;N-(2-ethylsulfanylethyl)-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(2-pyridin-3-ylethyl)thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(thiophen-2-ylmethyl)thiophene-2-carboxamide?
The InChIKey is ILLKCVPCGBZCCE-UHFFFAOYSA-N. The full InChI is InChI=1S/C17H12F5N3OS.C17H15F3N4OS.C15H12F3N3OS2.C14H16F3N3OS2.C14H12F3N3OS/c1-25-15(17(20,21)22)7-12(24-25)13-2-3-14(27-13)16(26)23-8-9-4-10(18)6-11(19)5-9;1-24-15(17(18,19)20)9-12(23-24)13-4-5-14(26-13)16(25)22-8-6-11-3-2-7-21-10-11;1-21-13(15(16,17)18)7-10(20-21)11-4-5-12(24-11)14(22)19-8-9-3-2-6-23-9;1-3-22-7-6-18-13(21)11-5-4-10(23-11)9-8-12(14(15,16)17)20(2)19-9;1-19-12(14(15,16)17)8-9(18-19)10-4-5-11(22-10)13(21)20-6-2-3-7-20/h2-7H,8H2,1H3,(H,23,26);2-5,7,9-10H,6,8H2,1H3,(H,22,25);2-7H,8H2,1H3,(H,19,22);4-5,8H,3,6-7H2,1-2H3,(H,18,21);2-5,8H,6-7H2,1H3.
What are the key properties of N-[(3,5-difluorophenyl)methyl]-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;2,5-dihydropyrrol-1-yl-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;N-(2-ethylsulfanylethyl)-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(2-pyridin-3-ylethyl)thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(thiophen-2-ylmethyl)thiophene-2-carboxamide?
N-[(3,5-difluorophenyl)methyl]-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;2,5-dihydropyrrol-1-yl-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;N-(2-ethylsulfanylethyl)-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(2-pyridin-3-ylethyl)thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(thiophen-2-ylmethyl)thiophene-2-carboxamide has a molecular weight of 1843.92 g/mol, XLogP of 18.90, 21 rotatable bonds, 4 hydrogen bond donors, and 23 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(3,5-difluorophenyl)methyl]-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;2,5-dihydropyrrol-1-yl-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;N-(2-ethylsulfanylethyl)-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(2-pyridin-3-ylethyl)thiophene-2-carboxamide;5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]-N-(thiophen-2-ylmethyl)thiophene-2-carboxamide is sourced from PubChem (CID 158734072), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).