N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-morpholin-4-yl-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide;6-morpholin-4-yl-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide

C174H166Cl7F23N46O18 — CID 158735795

IUPACN-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-morpholin-4-yl-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide;6-morpholin-4-yl-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
SMILESO=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCCC3(CCN3)C2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(C3CC3)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(CC(F)(F)F)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(CC(F)F)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(CCF)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCNC3(CC3)C2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCOCC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CCOCC2)c(-c2ccn[nH]2)c1
InChIInChI=1S/2C23H23ClF2N6O2.C22H20ClF5N6O2.C22H21ClF4N6O2.C22H22ClF3N6O2.C22H21ClF2N6O2.C20H18ClF2N5O3.C20H18F3N5O3/c24-23(25,26)34-18-5-1-16(2-6-18)29-22(33)15-13-19(20-7-8-28-30-20)21(27-14-15)32-11-9-31(10-12-32)17-3-4-17;24-23(25,26)34-17-4-2-16(3-5-17)30-21(33)15-12-18(19-6-9-29-31-19)20(27-13-15)32-11-1-7-22(14-32)8-10-28-22;23-22(27,28)36-16-3-1-15(2-4-16)31-20(35)14-11-17(18-5-6-30-32-18)19(29-12-14)34-9-7-33(8-10-34)13-21(24,25)26;23-22(26,27)35-16-3-1-15(2-4-16)30-21(34)14-11-17(18-5-6-29-31-18)20(28-12-14)33-9-7-32(8-10-33)13-19(24)25;23-22(25,26)34-17-3-1-16(2-4-17)29-21(33)15-13-18(19-5-7-28-30-19)20(27-14-15)32-11-9-31(8-6-24)10-12-32;23-22(24,25)33-16-3-1-15(2-4-16)29-20(32)14-11-17(18-5-8-28-30-18)19(26-12-14)31-10-9-27-21(13-31)6-7-21;2*21-20(22,23)31-15-3-1-14(2-4-15)26-19(29)13-11-16(17-5-6-25-27-17)18(24-12-13)28-7-9-30-10-8-28/h1-2,5-8,13-14,17H,3-4,9-12H2,(H,28,30)(H,29,33);2-6,9,12-13,28H,1,7-8,10-11,14H2,(H,29,31)(H,30,33);1-6,11-12H,7-10,13H2,(H,30,32)(H,31,35);1-6,11-12,19H,7-10,13H2,(H,29,31)(H,30,34);1-5,7,13-14H,6,8-12H2,(H,28,30)(H,29,33);1-5,8,11-12,27H,6-7,9-10,13H2,(H,28,30)(H,29,32);2*1-6,11-12H,7-10H2,(H,25,27)(H,26,29)
InChIKeyILQVOJPZHMCSIG-UHFFFAOYSA-N
MW3874.67 g/mol
LogP32.26
Rot. Bonds53

About N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-morpholin-4-yl-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide;6-morpholin-4-yl-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide

N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-morpholin-4-yl-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide;6-morpholin-4-yl-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide (PubChem CID 158735795) has the molecular formula C174H166Cl7F23N46O18 and a molecular weight of 3874.67 g/mol. Its IUPAC name is N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-morpholin-4-yl-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide;6-morpholin-4-yl-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide.

Molecular Properties

Compound NameN-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-morpholin-4-yl-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide;6-morpholin-4-yl-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
PubChem CID158735795
Molecular FormulaC174H166Cl7F23N46O18
Molecular Weight3874.67 g/mol
Exact Mass3869.09
IUPAC NameN-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-morpholin-4-yl-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide;6-morpholin-4-yl-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
SMILESO=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCCC3(CCN3)C2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(C3CC3)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(CC(F)(F)F)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(CC(F)F)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(CCF)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCNC3(CC3)C2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCOCC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CCOCC2)c(-c2ccn[nH]2)c1
InChIInChI=1S/2C23H23ClF2N6O2.C22H20ClF5N6O2.C22H21ClF4N6O2.C22H22ClF3N6O2.C22H21ClF2N6O2.C20H18ClF2N5O3.C20H18F3N5O3/c24-23(25,26)34-18-5-1-16(2-6-18)29-22(33)15-13-19(20-7-8-28-30-20)21(27-14-15)32-11-9-31(10-12-32)17-3-4-17;24-23(25,26)34-17-4-2-16(3-5-17)30-21(33)15-12-18(19-6-9-29-31-19)20(27-13-15)32-11-1-7-22(14-32)8-10-28-22;23-22(27,28)36-16-3-1-15(2-4-16)31-20(35)14-11-17(18-5-6-30-32-18)19(29-12-14)34-9-7-33(8-10-34)13-21(24,25)26;23-22(26,27)35-16-3-1-15(2-4-16)30-21(34)14-11-17(18-5-6-29-31-18)20(28-12-14)33-9-7-32(8-10-33)13-19(24)25;23-22(25,26)34-17-3-1-16(2-4-17)29-21(33)15-13-18(19-5-7-28-30-19)20(27-14-15)32-11-9-31(8-6-24)10-12-32;23-22(24,25)33-16-3-1-15(2-4-16)29-20(32)14-11-17(18-5-8-28-30-18)19(26-12-14)31-10-9-27-21(13-31)6-7-21;2*21-20(22,23)31-15-3-1-14(2-4-15)26-19(29)13-11-16(17-5-6-25-27-17)18(24-12-13)28-7-9-30-10-8-28/h1-2,5-8,13-14,17H,3-4,9-12H2,(H,28,30)(H,29,33);2-6,9,12-13,28H,1,7-8,10-11,14H2,(H,29,31)(H,30,33);1-6,11-12H,7-10,13H2,(H,30,32)(H,31,35);1-6,11-12,19H,7-10,13H2,(H,29,31)(H,30,34);1-5,7,13-14H,6,8-12H2,(H,28,30)(H,29,33);1-5,8,11-12,27H,6-7,9-10,13H2,(H,28,30)(H,29,32);2*1-6,11-12H,7-10H2,(H,25,27)(H,26,29)
InChIKeyILQVOJPZHMCSIG-UHFFFAOYSA-N
XLogP32.26
TPSA720.60 Ų
H-Bond Donors18
H-Bond Acceptors48
Rotatable Bonds53
Heavy Atoms268
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003874.67
LogP ≤ 532.26
H-Bond Donors ≤ 518
H-Bond Acceptors ≤ 1048

Analyze N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-morpholin-4-yl-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide;6-morpholin-4-yl-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide with MolForge

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Related Compounds

N-[4-[chloro(difluoro)methoxy]phenyl]-6-[3-[3-[5-[[4-[chloro(difluoro)methoxy]phenyl]carbamoyl]-2-(3-hydroxyazetidin-1-yl)pyridin-3-yl]-4-fluoro-1H-pyrazol-5-yl]piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide
CID 134267483
N-[4-[chloro(difluoro)methoxy]phenyl]-6-[5-[3-[5-[[4-[chloro(difluoro)methoxy]phenyl]carbamoyl]-2-(4-cyclopropylpiperazin-1-yl)pyridin-3-yl]-1H-pyrazol-5-yl]-4,7-diazaspiro[2.5]octan-7-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide
CID 134267487
4-chloro-3-(2-methoxypyrimidin-5-yl)-N-[4-(trifluoromethoxy)phenyl]benzamide;4-chloro-3-(1-methylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]benzamide;4-chloro-3-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]benzamide;4-chloro-3-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;4-chloro-3-pyridin-4-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;4-chloro-3-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;4-fluoro-3-(1-methylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]benzamide;4-fluoro-3-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]benzamide;4-fluoro-3-pyridin-4-yl-N-[4-(trifluoromethoxy)phenyl]benzamide;5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
CID 157055013
6-(1-amino-3-azabicyclo[3.1.0]hexan-3-yl)-N-[4-[chloro(difluoro)methoxy]phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(1S,5R)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-N-[4-[chloro(difluoro)methoxy]phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(1R,5S)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3S,4S)-3,4-dihydroxypyrrolidin-1-yl]-5-(2-methylpyrimidin-5-yl)pyridine-3-carboxamide;6-(4,6-dihydro-1H-pyrrolo[3,4-d]pyrazol-5-yl)-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3S,4S)-3-(dimethylamino)-4-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
CID 157157075
4-[(3S,4S)-3-amino-4-hydroxypyrrolidin-1-yl]-N-[4-[chloro(difluoro)methoxy]phenyl]-3-(1H-pyrazol-5-yl)benzamide;6-[(3S,4S)-3-amino-4-methoxypyrrolidin-1-yl]-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-4-[(3S,4S)-3,4-dihydroxypyrrolidin-1-yl]-3-(1H-pyrazol-5-yl)benzamide;5-(3-cyano-1H-pyrazol-5-yl)-6-pyrrolidin-1-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3S,4S)-3-fluoro-4-hydroxypyrrolidin-1-yl]-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[5-(hydroxymethyl)-1H-pyrazol-3-yl]-6-pyrrolidin-1-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(1H-pyrazol-5-yl)-6-pyrrolidin-1-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
CID 157422805
N-cyclohexyl-N-methyl-4-[(3-methyl-2H-pyrazolo[4,3-c]pyridin-4-yl)amino]benzamide;N-cyclopentyl-4-[(3-methyl-2H-pyrazolo[4,3-c]pyridin-4-yl)amino]benzamide;(4,4-difluoropiperidin-1-yl)-[4-[(3-methyl-2H-pyrazolo[4,3-c]pyridin-4-yl)amino]phenyl]methanone;N-(2-methoxyethyl)-4-[(3-methyl-2H-pyrazolo[4,3-c]pyridin-4-yl)amino]benzamide;(4-methoxyphenyl)-[4-[(3-methyl-2H-pyrazolo[4,3-c]pyridin-4-yl)amino]cyclohexyl]methanone;N-methyl-4-[(3-methyl-2H-pyrazolo[4,3-c]pyridin-4-yl)amino]-N-phenylbenzamide
CID 157550007
6-[(3S,4S)-3-amino-4-hydroxypyrrolidin-1-yl]-N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;6-[(3S,4S)-3-amino-4-methoxypyrrolidin-1-yl]-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3S,4S)-3,4-dihydroxypyrrolidin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;5-(3-cyano-1H-pyrazol-5-yl)-6-pyrrolidin-1-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3S,4S)-3-fluoro-4-hydroxypyrrolidin-1-yl]-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[5-(hydroxymethyl)-1H-pyrazol-3-yl]-6-pyrrolidin-1-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(1H-pyrazol-5-yl)-6-pyrrolidin-1-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
CID 157681388
6-[(3R)-3-(aminomethyl)pyrrolidin-1-yl]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3S)-3-aminopyrrolidin-1-yl]-5-(6-methyl-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-(methylamino)pyrrolidin-1-yl]-5-(6-methyl-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3S)-3-(methylamino)pyrrolidin-1-yl]-5-(6-methyl-3-pyridinyl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-(methylamino)pyrrolidin-1-yl]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3S)-3-(methylamino)pyrrolidin-1-yl]-5-pyridin-3-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
CID 157735157
N-cyclohexyl-N-methyl-4-[(3-methyl-2H-pyrazolo[4,3-c]pyridin-4-yl)amino]benzamide;N-cyclopentyl-4-[(3-methyl-2H-pyrazolo[4,3-c]pyridin-4-yl)amino]benzamide;(4,4-difluoropiperidin-1-yl)-[4-[(3-methyl-2H-pyrazolo[4,3-c]pyridin-4-yl)amino]phenyl]methanone;N-(2-methoxyethyl)-4-[(3-methyl-2H-pyrazolo[4,3-c]pyridin-4-yl)amino]benzamide;N-(2-methoxyphenyl)-4-[(3-methyl-2H-pyrazolo[4,3-c]pyridin-4-yl)amino]benzamide;N-methyl-4-[(3-methyl-2H-pyrazolo[4,3-c]pyridin-4-yl)amino]-N-phenylbenzamide
CID 158017550
6-[(3S,4S)-3-amino-4-hydroxypyrrolidin-1-yl]-N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;5-(3-cyano-1H-pyrazol-5-yl)-6-pyrrolidin-1-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3S,4S)-3-fluoro-4-hydroxypyrrolidin-1-yl]-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-[5-(hydroxymethyl)-1H-pyrazol-3-yl]-6-pyrrolidin-1-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;5-(1H-pyrazol-5-yl)-6-pyrrolidin-1-yl-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
CID 158304871
bis(N-[4-[chloro(difluoro)methoxy]phenyl]-5-(5-cyano-1H-pyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide);N-[4-[chloro(difluoro)methoxy]phenyl]-6-[[(3S)-3,4-dihydroxybutyl]amino]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[[(3R)-3,4-dihydroxybutyl]amino]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)pyridine-3-carboxamide;5-(5-cyano-1H-pyrrol-2-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrrol-2-yl)-N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-3-carboxamide
CID 158349981
N-[4-[chloro(difluoro)methoxy]phenyl]-5-(4-fluoro-1H-pyrazol-5-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-[1-(2-hydroxyethyl)pyrazol-4-yl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(2-methylpyrazol-3-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(5-methyl-1H-pyrazol-3-yl)pyridine-3-carboxamide;5-(4-fluoro-1H-pyrazol-5-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(4-methyl-1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(5-methyl-1H-pyrazol-3-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide
CID 158499747

Frequently Asked Questions

What is the IUPAC name of N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-morpholin-4-yl-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide;6-morpholin-4-yl-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide?
The IUPAC name of N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-morpholin-4-yl-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide;6-morpholin-4-yl-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide (CID 158735795) is N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-morpholin-4-yl-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide;6-morpholin-4-yl-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide.
What is the SMILES notation for N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-morpholin-4-yl-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide;6-morpholin-4-yl-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide?
The canonical SMILES for N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-morpholin-4-yl-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide;6-morpholin-4-yl-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide is O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCCC3(CCN3)C2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(C3CC3)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(CC(F)(F)F)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(CC(F)F)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCN(CCF)CC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCNC3(CC3)C2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCOCC2)c(-c2ccn[nH]2)c1.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CCOCC2)c(-c2ccn[nH]2)c1.
What is the InChIKey of N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-morpholin-4-yl-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide;6-morpholin-4-yl-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide?
The InChIKey is ILQVOJPZHMCSIG-UHFFFAOYSA-N. The full InChI is InChI=1S/2C23H23ClF2N6O2.C22H20ClF5N6O2.C22H21ClF4N6O2.C22H22ClF3N6O2.C22H21ClF2N6O2.C20H18ClF2N5O3.C20H18F3N5O3/c24-23(25,26)34-18-5-1-16(2-6-18)29-22(33)15-13-19(20-7-8-28-30-20)21(27-14-15)32-11-9-31(10-12-32)17-3-4-17;24-23(25,26)34-17-4-2-16(3-5-17)30-21(33)15-12-18(19-6-9-29-31-19)20(27-13-15)32-11-1-7-22(14-32)8-10-28-22;23-22(27,28)36-16-3-1-15(2-4-16)31-20(35)14-11-17(18-5-6-30-32-18)19(29-12-14)34-9-7-33(8-10-34)13-21(24,25)26;23-22(26,27)35-16-3-1-15(2-4-16)30-21(34)14-11-17(18-5-6-29-31-18)20(28-12-14)33-9-7-32(8-10-33)13-19(24)25;23-22(25,26)34-17-3-1-16(2-4-17)29-21(33)15-13-18(19-5-7-28-30-19)20(27-14-15)32-11-9-31(8-6-24)10-12-32;23-22(24,25)33-16-3-1-15(2-4-16)29-20(32)14-11-17(18-5-8-28-30-18)19(26-12-14)31-10-9-27-21(13-31)6-7-21;2*21-20(22,23)31-15-3-1-14(2-4-15)26-19(29)13-11-16(17-5-6-25-27-17)18(24-12-13)28-7-9-30-10-8-28/h1-2,5-8,13-14,17H,3-4,9-12H2,(H,28,30)(H,29,33);2-6,9,12-13,28H,1,7-8,10-11,14H2,(H,29,31)(H,30,33);1-6,11-12H,7-10,13H2,(H,30,32)(H,31,35);1-6,11-12,19H,7-10,13H2,(H,29,31)(H,30,34);1-5,7,13-14H,6,8-12H2,(H,28,30)(H,29,33);1-5,8,11-12,27H,6-7,9-10,13H2,(H,28,30)(H,29,32);2*1-6,11-12H,7-10H2,(H,25,27)(H,26,29).
What are the key properties of N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-morpholin-4-yl-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide;6-morpholin-4-yl-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide?
N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-morpholin-4-yl-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide;6-morpholin-4-yl-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide has a molecular weight of 3874.67 g/mol, XLogP of 32.26, 53 rotatable bonds, 18 hydrogen bond donors, and 48 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4-cyclopropylpiperazin-1-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(1,8-diazaspiro[3.5]nonan-8-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-(4,7-diazaspiro[2.5]octan-7-yl)-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2,2-difluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-[4-(2-fluoroethyl)piperazin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-6-morpholin-4-yl-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide;N-[4-[chloro(difluoro)methoxy]phenyl]-5-(1H-pyrazol-5-yl)-6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]pyridine-3-carboxamide;6-morpholin-4-yl-5-(1H-pyrazol-5-yl)-N-[4-(trifluoromethoxy)phenyl]pyridine-3-carboxamide is sourced from PubChem (CID 158735795), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).