N-[(2S)-1-(azetidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl]-3-(3,4-difluorophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3-chloro-4-pyridinyl)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(ethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(2-fluoroethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-3-(1,3-thiazol-2-yl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide

C127H162ClF9N26O12S — CID 158737049

IUPACN-[(2S)-1-(azetidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl]-3-(3,4-difluorophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3-chloro-4-pyridinyl)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(ethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(2-fluoroethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-3-(1,3-thiazol-2-yl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide
SMILESCC(C)(C)[C@H](NC(=O)c1nc(-c2ccc(F)c(F)c2)n2c1CCCC2)C(=O)N1CCC1.CC(C)(C)[C@H](NC(=O)c1nc(-c2ccc(F)c(F)c2)n2c1CCCC2)C(=O)NCCF.CCNC(=O)[C@@H](NC(=O)c1nc(-c2ccc(F)c(F)c2)n2c1CCCC2)C(C)(C)C.CN(C)C(=O)[C@@H](NC(=O)c1nc(-c2ccc(F)c(F)c2)n2c1CCCC2)C(C)(C)C.CNC(=O)[C@@H](NC(=O)c1nc(-c2ccncc2Cl)n2c1CCCC2)C(C)(C)C.CNC(=O)[C@@H](NC(=O)c1nc(-c2nccs2)n2c1CCCC2)C(C)(C)C
InChIInChI=1S/C23H28F2N4O2.C22H27F3N4O2.2C22H28F2N4O2.C20H26ClN5O2.C18H25N5O2S/c1-23(2,3)19(22(31)28-10-6-11-28)27-21(30)18-17-7-4-5-12-29(17)20(26-18)14-8-9-15(24)16(25)13-14;1-22(2,3)18(21(31)26-10-9-23)28-20(30)17-16-6-4-5-11-29(16)19(27-17)13-7-8-14(24)15(25)12-13;1-22(2,3)18(21(30)27(4)5)26-20(29)17-16-8-6-7-11-28(16)19(25-17)13-9-10-14(23)15(24)12-13;1-5-25-21(30)18(22(2,3)4)27-20(29)17-16-8-6-7-11-28(16)19(26-17)13-9-10-14(23)15(24)12-13;1-20(2,3)16(19(28)22-4)25-18(27)15-14-7-5-6-10-26(14)17(24-15)12-8-9-23-11-13(12)21;1-18(2,3)13(16(25)19-4)22-15(24)12-11-7-5-6-9-23(11)14(21-12)17-20-8-10-26-17/h8-9,13,19H,4-7,10-12H2,1-3H3,(H,27,30);7-8,12,18H,4-6,9-11H2,1-3H3,(H,26,31)(H,28,30);9-10,12,18H,6-8,11H2,1-5H3,(H,26,29);9-10,12,18H,5-8,11H2,1-4H3,(H,25,30)(H,27,29);8-9,11,16H,5-7,10H2,1-4H3,(H,22,28)(H,25,27);8,10,13H,5-7,9H2,1-4H3,(H,19,25)(H,22,24)/t19-;3*18-;16-;13-/m111111/s1
InChIKeyILUSBTAGNZAZEE-UDWLJGKVSA-N
MW2483.36 g/mol
LogP18.84
Rot. Bonds27

About N-[(2S)-1-(azetidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl]-3-(3,4-difluorophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3-chloro-4-pyridinyl)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(ethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(2-fluoroethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-3-(1,3-thiazol-2-yl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide

N-[(2S)-1-(azetidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl]-3-(3,4-difluorophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3-chloro-4-pyridinyl)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(ethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(2-fluoroethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-3-(1,3-thiazol-2-yl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide (PubChem CID 158737049) has the molecular formula C127H162ClF9N26O12S and a molecular weight of 2483.36 g/mol. Its IUPAC name is N-[(2S)-1-(azetidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl]-3-(3,4-difluorophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3-chloro-4-pyridinyl)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(ethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(2-fluoroethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-3-(1,3-thiazol-2-yl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide.

Molecular Properties

Compound NameN-[(2S)-1-(azetidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl]-3-(3,4-difluorophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3-chloro-4-pyridinyl)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(ethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(2-fluoroethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-3-(1,3-thiazol-2-yl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide
PubChem CID158737049
Molecular FormulaC127H162ClF9N26O12S
Molecular Weight2483.36 g/mol
Exact Mass2481.21
IUPAC NameN-[(2S)-1-(azetidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl]-3-(3,4-difluorophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3-chloro-4-pyridinyl)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(ethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(2-fluoroethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-3-(1,3-thiazol-2-yl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide
SMILESCC(C)(C)[C@H](NC(=O)c1nc(-c2ccc(F)c(F)c2)n2c1CCCC2)C(=O)N1CCC1.CC(C)(C)[C@H](NC(=O)c1nc(-c2ccc(F)c(F)c2)n2c1CCCC2)C(=O)NCCF.CCNC(=O)[C@@H](NC(=O)c1nc(-c2ccc(F)c(F)c2)n2c1CCCC2)C(C)(C)C.CN(C)C(=O)[C@@H](NC(=O)c1nc(-c2ccc(F)c(F)c2)n2c1CCCC2)C(C)(C)C.CNC(=O)[C@@H](NC(=O)c1nc(-c2ccncc2Cl)n2c1CCCC2)C(C)(C)C.CNC(=O)[C@@H](NC(=O)c1nc(-c2nccs2)n2c1CCCC2)C(C)(C)C
InChIInChI=1S/C23H28F2N4O2.C22H27F3N4O2.2C22H28F2N4O2.C20H26ClN5O2.C18H25N5O2S/c1-23(2,3)19(22(31)28-10-6-11-28)27-21(30)18-17-7-4-5-12-29(17)20(26-18)14-8-9-15(24)16(25)13-14;1-22(2,3)18(21(31)26-10-9-23)28-20(30)17-16-6-4-5-11-29(16)19(27-17)13-7-8-14(24)15(25)12-13;1-22(2,3)18(21(30)27(4)5)26-20(29)17-16-8-6-7-11-28(16)19(25-17)13-9-10-14(23)15(24)12-13;1-5-25-21(30)18(22(2,3)4)27-20(29)17-16-8-6-7-11-28(16)19(26-17)13-9-10-14(23)15(24)12-13;1-20(2,3)16(19(28)22-4)25-18(27)15-14-7-5-6-10-26(14)17(24-15)12-8-9-23-11-13(12)21;1-18(2,3)13(16(25)19-4)22-15(24)12-11-7-5-6-9-23(11)14(21-12)17-20-8-10-26-17/h8-9,13,19H,4-7,10-12H2,1-3H3,(H,27,30);7-8,12,18H,4-6,9-11H2,1-3H3,(H,26,31)(H,28,30);9-10,12,18H,6-8,11H2,1-5H3,(H,26,29);9-10,12,18H,5-8,11H2,1-4H3,(H,25,30)(H,27,29);8-9,11,16H,5-7,10H2,1-4H3,(H,22,28)(H,25,27);8,10,13H,5-7,9H2,1-4H3,(H,19,25)(H,22,24)/t19-;3*18-;16-;13-/m111111/s1
InChIKeyILUSBTAGNZAZEE-UDWLJGKVSA-N
XLogP18.84
TPSA464.32 Ų
H-Bond Donors10
H-Bond Acceptors27
Rotatable Bonds27
Heavy Atoms176
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002483.36
LogP ≤ 518.84
H-Bond Donors ≤ 510
H-Bond Acceptors ≤ 1027

Analyze N-[(2S)-1-(azetidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl]-3-(3,4-difluorophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3-chloro-4-pyridinyl)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(ethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(2-fluoroethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-3-(1,3-thiazol-2-yl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide with MolForge

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Related Compounds

(2S)-N-[6-[2-(3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-5-yl]-2-pyridinyl]-2-[1-(cyanomethyl)-3-methyl-2,6-dioxopurin-7-yl]propanamide;N-[6-(4-chlorophenyl)-2-pyridinyl]-2-[3,8-dimethyl-2,6-dioxo-1-(2-oxopropyl)purin-7-yl]acetamide;2-[1-(cyanomethyl)-3-methyl-2,6-dioxopurin-7-yl]-N-[6-[2-(1,1-difluoroethyl)pyrimidin-5-yl]-2-pyridinyl]acetamide;N-[2-[2-(1,1-difluoroethyl)pyrimidin-5-yl]-1,3-thiazol-4-yl]-2-[3-methyl-2,6-dioxo-1-(pyridin-2-ylmethyl)purin-7-yl]acetamide;(2S)-N-[2-(5-fluoro-6-methyl-3-pyridinyl)-1,3-thiazol-4-yl]-2-[3-methyl-2,6-dioxo-1-(2-oxobutyl)purin-7-yl]propanamide
CID 157420675
2-[1-[[6-(2-acetamidoethylamino)pyrimidine-4-carbonyl]amino]ethyl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-4-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-[6-(2-methylimidazol-1-yl)pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-[6-[3-(4-methylpiperazin-1-yl)propylamino]pyrimidin-4-yl]-4-oxobutan-2-yl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[1-[[6-(3-piperidin-4-ylpropyl)pyrimidine-4-carbonyl]amino]ethyl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[1-[(6-pyrrol-1-ylpyrimidine-4-carbonyl)amino]ethyl]-1,3-thiazole-5-carboxamide
CID 157678747
[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(5-chloro-2-methyl-4-pyridinyl)methanone;[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(4-fluoro-3-methylphenyl)methanone;[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(3-fluoro-5-methyl-2-pyridinyl)methanone;[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(4-methyl-2-propan-2-ylpyrimidin-5-yl)methanone;[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(1,3-thiazol-2-yl)methanone;[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-[2-(trifluoromethyl)phenyl]methanone
CID 157742918
CID 158566393
CID 158566393
[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(2,5-dichloro-4-pyridinyl)methanone;[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(3,5-difluoro-2-pyridinyl)methanone;[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(4-fluoro-3-methylphenyl)methanone;[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(4-methyl-2-propan-2-ylpyrimidin-5-yl)methanone;[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(1,3-thiazol-2-yl)methanone;[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-[2-(trifluoromethyl)phenyl]methanone
CID 160478617
N-(6-chloro-[1,3]thiazolo[4,5-c]pyridin-2-yl)benzamide;N-(6-methyl-[1,3]thiazolo[4,5-b]pyridin-2-yl)benzamide;N-(6-methyl-[1,3]thiazolo[4,5-c]pyridin-2-yl)pyridine-2-carboxamide;N-(6-methyl-[1,3]thiazolo[4,5-c]pyridin-2-yl)pyridine-3-carboxamide;N-(6-methyl-[1,3]thiazolo[4,5-c]pyridin-2-yl)pyrimidine-5-carboxamide;N-(6-methyl-[1,3]thiazolo[4,5-c]pyridin-2-yl)-1,2-thiazole-3-carboxamide;N-(6-methyl-[1,3]thiazolo[4,5-c]pyridin-2-yl)-1,3-thiazole-4-carboxamide;N-[6-(trifluoromethyl)-[1,3]thiazolo[4,5-c]pyridin-2-yl]pyrimidine-2-carboxamide
CID 161163173
6-N-(azetidin-3-yl)-4-N-[(1R)-1-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]ethyl]pyrimidine-4,6-dicarboxamide;4-N-[(1R)-1-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]ethyl]-6-N-ethylpyrimidine-4,6-dicarboxamide;4-N-[(1R)-1-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]ethyl]-6-N-methylpyrimidine-4,6-dicarboxamide;4-N-[(1R)-1-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]ethyl]-6-N-piperidin-4-ylpyrimidine-4,6-dicarboxamide;4-N-[1-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]ethyl]-6-N-(pyridin-3-ylmethyl)pyrimidine-4,6-dicarboxamide;4-N-[(1R)-1-[5-[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]carbamoyl]-1,3-thiazol-2-yl]ethyl]pyrimidine-4,6-dicarboxamide
CID 161202958
8-[(2-Chloroimidazo[2,1-b][1,3]thiazol-6-yl)methyl]-7-[[4-(3,3-difluoroazetidin-1-yl)phenyl]methyl]-3-ethylpurine-2,6-dione;3-ethyl-7-[(4-imidazol-1-ylphenyl)methyl]-8-(5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-2-ylmethyl)purine-2,6-dione;3-ethyl-7-[[4-(2-oxopropyl)phenyl]methyl]-8-(5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-2-ylmethyl)purine-2,6-dione;3-ethyl-7-[[4-(2-oxopyrrolidin-1-yl)phenyl]methyl]-8-(5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-2-ylmethyl)purine-2,6-dione
CID 161247676
2-[(2S)-4-[6-[2-(azetidin-3-yl)acetyl]pyrimidin-4-yl]-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;2-[(2S)-4-(6-carbamoylpyrimidin-4-yl)-4-oxobutan-2-yl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[(2S)-4-oxo-4-[6-(2-piperidin-4-ylacetyl)pyrimidin-4-yl]butan-2-yl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[(2S)-4-oxo-4-(6-propanoylpyrimidin-4-yl)butan-2-yl]-1,3-thiazole-5-carboxamide;N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[4-oxo-4-[6-(3-pyridin-3-ylpropanoyl)pyrimidin-4-yl]butan-2-yl]-1,3-thiazole-5-carboxamide
CID 161561812
N-[5-(4-benzylpiperazin-1-yl)-2-pyridinyl]-2-(1,3-dimethyl-2,6-dioxopurin-7-yl)acetamide;N-[5-[4-[(3,5-difluorophenyl)methyl]piperazin-1-yl]-2-pyridinyl]-2-(1,3-dimethyl-2,6-dioxopurin-7-yl)acetamide;2-(1,3-dimethyl-2,6-dioxopurin-7-yl)-N-[5-[4-(3-fluorobenzoyl)piperazin-1-yl]-2-pyridinyl]acetamide;2-(1,3-dimethyl-2,6-dioxopurin-7-yl)-N-[5-[4-(4-fluorobenzoyl)piperazin-1-yl]-2-pyridinyl]acetamide;2-(1,3-dimethyl-2,6-dioxopurin-7-yl)-N-[5-[4-(thiophene-2-carbonyl)piperazin-1-yl]-2-pyridinyl]acetamide
CID 157229689
N-[(2S)-1-(azetidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl]-3-(3,4-difluorophenyl)-6,8-dihydro-5H-imidazo[5,1-c][1,4]oxazine-1-carboxamide;3-(4-chloro-2-fluorophenyl)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-6,8-dihydro-5H-imidazo[5,1-c][1,4]oxazine-1-carboxamide;3-(3-chloro-4-pyridinyl)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-6,8-dihydro-5H-imidazo[5,1-c][1,4]oxazine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(1S)-2,2-dimethyl-1-(3-methyl-1,2,4-oxadiazol-5-yl)propyl]-6,8-dihydro-5H-imidazo[5,1-c][1,4]oxazine-1-carboxamide;N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-3-(1,3-thiazol-2-yl)-6,8-dihydro-5H-imidazo[5,1-c][1,4]oxazine-1-carboxamide
CID 157618793
3-(4-chloro-2-fluorophenyl)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-6,7,8,9-tetrahydro-5H-imidazo[1,5-a]azepine-1-carboxamide;3-(3-chloro-4-pyridinyl)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-6,7,8,9-tetrahydro-5H-imidazo[1,5-a]azepine-1-carboxamide;N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-7,7-dimethyl-3-phenyl-5,6,8,9-tetrahydroimidazo[1,5-a]azepine-1-carboxamide;N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-3-(1,3-thiazol-2-yl)-6,7,8,9-tetrahydro-5H-imidazo[1,5-a]azepine-1-carboxamide
CID 157756360

Frequently Asked Questions

What is the IUPAC name of N-[(2S)-1-(azetidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl]-3-(3,4-difluorophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3-chloro-4-pyridinyl)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(ethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(2-fluoroethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-3-(1,3-thiazol-2-yl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide?
The IUPAC name of N-[(2S)-1-(azetidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl]-3-(3,4-difluorophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3-chloro-4-pyridinyl)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(ethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(2-fluoroethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-3-(1,3-thiazol-2-yl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide (CID 158737049) is N-[(2S)-1-(azetidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl]-3-(3,4-difluorophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3-chloro-4-pyridinyl)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(ethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(2-fluoroethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-3-(1,3-thiazol-2-yl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide.
What is the SMILES notation for N-[(2S)-1-(azetidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl]-3-(3,4-difluorophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3-chloro-4-pyridinyl)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(ethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(2-fluoroethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-3-(1,3-thiazol-2-yl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide?
The canonical SMILES for N-[(2S)-1-(azetidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl]-3-(3,4-difluorophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3-chloro-4-pyridinyl)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(ethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(2-fluoroethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-3-(1,3-thiazol-2-yl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide is CC(C)(C)[C@H](NC(=O)c1nc(-c2ccc(F)c(F)c2)n2c1CCCC2)C(=O)N1CCC1.CC(C)(C)[C@H](NC(=O)c1nc(-c2ccc(F)c(F)c2)n2c1CCCC2)C(=O)NCCF.CCNC(=O)[C@@H](NC(=O)c1nc(-c2ccc(F)c(F)c2)n2c1CCCC2)C(C)(C)C.CN(C)C(=O)[C@@H](NC(=O)c1nc(-c2ccc(F)c(F)c2)n2c1CCCC2)C(C)(C)C.CNC(=O)[C@@H](NC(=O)c1nc(-c2ccncc2Cl)n2c1CCCC2)C(C)(C)C.CNC(=O)[C@@H](NC(=O)c1nc(-c2nccs2)n2c1CCCC2)C(C)(C)C.
What is the InChIKey of N-[(2S)-1-(azetidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl]-3-(3,4-difluorophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3-chloro-4-pyridinyl)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(ethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(2-fluoroethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-3-(1,3-thiazol-2-yl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide?
The InChIKey is ILUSBTAGNZAZEE-UDWLJGKVSA-N. The full InChI is InChI=1S/C23H28F2N4O2.C22H27F3N4O2.2C22H28F2N4O2.C20H26ClN5O2.C18H25N5O2S/c1-23(2,3)19(22(31)28-10-6-11-28)27-21(30)18-17-7-4-5-12-29(17)20(26-18)14-8-9-15(24)16(25)13-14;1-22(2,3)18(21(31)26-10-9-23)28-20(30)17-16-6-4-5-11-29(16)19(27-17)13-7-8-14(24)15(25)12-13;1-22(2,3)18(21(30)27(4)5)26-20(29)17-16-8-6-7-11-28(16)19(25-17)13-9-10-14(23)15(24)12-13;1-5-25-21(30)18(22(2,3)4)27-20(29)17-16-8-6-7-11-28(16)19(26-17)13-9-10-14(23)15(24)12-13;1-20(2,3)16(19(28)22-4)25-18(27)15-14-7-5-6-10-26(14)17(24-15)12-8-9-23-11-13(12)21;1-18(2,3)13(16(25)19-4)22-15(24)12-11-7-5-6-9-23(11)14(21-12)17-20-8-10-26-17/h8-9,13,19H,4-7,10-12H2,1-3H3,(H,27,30);7-8,12,18H,4-6,9-11H2,1-3H3,(H,26,31)(H,28,30);9-10,12,18H,6-8,11H2,1-5H3,(H,26,29);9-10,12,18H,5-8,11H2,1-4H3,(H,25,30)(H,27,29);8-9,11,16H,5-7,10H2,1-4H3,(H,22,28)(H,25,27);8,10,13H,5-7,9H2,1-4H3,(H,19,25)(H,22,24)/t19-;3*18-;16-;13-/m111111/s1.
What are the key properties of N-[(2S)-1-(azetidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl]-3-(3,4-difluorophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3-chloro-4-pyridinyl)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(ethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(2-fluoroethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-3-(1,3-thiazol-2-yl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide?
N-[(2S)-1-(azetidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl]-3-(3,4-difluorophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3-chloro-4-pyridinyl)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(ethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(2-fluoroethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-3-(1,3-thiazol-2-yl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide has a molecular weight of 2483.36 g/mol, XLogP of 18.84, 27 rotatable bonds, 10 hydrogen bond donors, and 27 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(2S)-1-(azetidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl]-3-(3,4-difluorophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3-chloro-4-pyridinyl)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(ethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;3-(3,4-difluorophenyl)-N-[(2S)-1-(2-fluoroethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide;N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-3-(1,3-thiazol-2-yl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine-1-carboxamide is sourced from PubChem (CID 158737049), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).