6-[2-(5-chloro-2-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine

C100H74Cl2F4N20 — CID 158738013

IUPAC6-[2-(5-chloro-2-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine
SMILESCc1c(Cl)cccc1-c1ncccc1-c1ccc2ncnc(N)c2c1.Cc1c(F)cccc1-c1ncccc1-c1ccc2ncnc(N)c2c1.Cc1cc(Cl)cc(-c2ncccc2-c2ccc3ncnc(N)c3c2)c1F.Cc1cc(F)ccc1-c1ncccc1-c1ccc2ncnc(N)c2c1.Cc1ccc(F)cc1-c1ncccc1-c1ccc2ncnc(N)c2c1
InChIInChI=1S/C20H14ClFN4.C20H15ClN4.3C20H15FN4/c1-11-7-13(21)9-16(18(11)22)19-14(3-2-6-24-19)12-4-5-17-15(8-12)20(23)26-10-25-17;2*1-12-14(4-2-6-17(12)21)19-15(5-3-9-23-19)13-7-8-18-16(10-13)20(22)25-11-24-18;1-12-9-14(21)5-6-15(12)19-16(3-2-8-23-19)13-4-7-18-17(10-13)20(22)25-11-24-18;1-12-4-6-14(21)10-16(12)19-15(3-2-8-23-19)13-5-7-18-17(9-13)20(22)25-11-24-18/h2-10H,1H3,(H2,23,25,26);4*2-11H,1H3,(H2,22,24,25)
InChIKeyILXUDTFUAMQQCN-UHFFFAOYSA-N
MW1702.73 g/mol
LogP23.11
Rot. Bonds10

About 6-[2-(5-chloro-2-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine

6-[2-(5-chloro-2-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine (PubChem CID 158738013) has the molecular formula C100H74Cl2F4N20 and a molecular weight of 1702.73 g/mol. Its IUPAC name is 6-[2-(5-chloro-2-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine.

Molecular Properties

Compound Name6-[2-(5-chloro-2-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine
PubChem CID158738013
Molecular FormulaC100H74Cl2F4N20
Molecular Weight1702.73 g/mol
Exact Mass1700.57
IUPAC Name6-[2-(5-chloro-2-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine
SMILESCc1c(Cl)cccc1-c1ncccc1-c1ccc2ncnc(N)c2c1.Cc1c(F)cccc1-c1ncccc1-c1ccc2ncnc(N)c2c1.Cc1cc(Cl)cc(-c2ncccc2-c2ccc3ncnc(N)c3c2)c1F.Cc1cc(F)ccc1-c1ncccc1-c1ccc2ncnc(N)c2c1.Cc1ccc(F)cc1-c1ncccc1-c1ccc2ncnc(N)c2c1
InChIInChI=1S/C20H14ClFN4.C20H15ClN4.3C20H15FN4/c1-11-7-13(21)9-16(18(11)22)19-14(3-2-6-24-19)12-4-5-17-15(8-12)20(23)26-10-25-17;2*1-12-14(4-2-6-17(12)21)19-15(5-3-9-23-19)13-7-8-18-16(10-13)20(22)25-11-24-18;1-12-9-14(21)5-6-15(12)19-16(3-2-8-23-19)13-4-7-18-17(10-13)20(22)25-11-24-18;1-12-4-6-14(21)10-16(12)19-15(3-2-8-23-19)13-5-7-18-17(9-13)20(22)25-11-24-18/h2-10H,1H3,(H2,23,25,26);4*2-11H,1H3,(H2,22,24,25)
InChIKeyILXUDTFUAMQQCN-UHFFFAOYSA-N
XLogP23.11
TPSA323.45 Ų
H-Bond Donors5
H-Bond Acceptors20
Rotatable Bonds10
Heavy Atoms126
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001702.73
LogP ≤ 523.11
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1020

Analyze 6-[2-(5-chloro-2-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine with MolForge

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Launch Full Analysis

Related Compounds

Aminoquinazoline, 18
CID 24863671
6-(2-chlorophenyl)-N-(3-pyridinylmethyl)-4-quinazolinamine
CID 3234184
6-[bis(4-chlorophenyl)methyl]-N-[[6-(trifluoromethyl)pyridin-3-yl]methyl]quinazolin-4-amine
CID 118916049
6-[bis(4-chlorophenyl)methyl]-N-[[5-(trifluoromethyl)pyridin-2-yl]methyl]quinazolin-4-amine
CID 118916205
6-[bis(4-chlorophenyl)methyl]-N-[[5-(trifluoromethyl)pyridin-3-yl]methyl]quinazolin-4-amine
CID 118916235
6-(3-chlorophenyl)-N-(3-pyridinylmethyl)-4-quinazolinamine
CID 44142056
N-[4-(2-chloro-4-fluorophenyl)-3-fluorophenyl]-2-pyridin-4-ylquinazolin-4-amine
CID 70789669
6-(2-aminopyrimidin-5-yl)-N-(3-chloro-4-fluorophenyl)quinazolin-4-amine
CID 121427581
6-(3-chlorophenyl)-N-(pyridin-4-yl)quinazolin-4-amine
CID 72703927
6-[bis(4-chlorophenyl)methyl]-N-[1-(pyridin-2-yl)piperidin-4-yl]quinazolin-4-amine
CID 118916190
6-(2-aminopyrimidin-5-yl)-N-(3-chloro-2-fluorophenyl)quinazolin-4-amine
CID 171341590
N-(3-chloro-4-fluorophenyl)-6-pyridin-3-ylquinazolin-4-amine
CID 22478370

Frequently Asked Questions

What is the IUPAC name of 6-[2-(5-chloro-2-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine?
The IUPAC name of 6-[2-(5-chloro-2-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine (CID 158738013) is 6-[2-(5-chloro-2-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine.
What is the SMILES notation for 6-[2-(5-chloro-2-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine?
The canonical SMILES for 6-[2-(5-chloro-2-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine is Cc1c(Cl)cccc1-c1ncccc1-c1ccc2ncnc(N)c2c1.Cc1c(F)cccc1-c1ncccc1-c1ccc2ncnc(N)c2c1.Cc1cc(Cl)cc(-c2ncccc2-c2ccc3ncnc(N)c3c2)c1F.Cc1cc(F)ccc1-c1ncccc1-c1ccc2ncnc(N)c2c1.Cc1ccc(F)cc1-c1ncccc1-c1ccc2ncnc(N)c2c1.
What is the InChIKey of 6-[2-(5-chloro-2-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine?
The InChIKey is ILXUDTFUAMQQCN-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H14ClFN4.C20H15ClN4.3C20H15FN4/c1-11-7-13(21)9-16(18(11)22)19-14(3-2-6-24-19)12-4-5-17-15(8-12)20(23)26-10-25-17;2*1-12-14(4-2-6-17(12)21)19-15(5-3-9-23-19)13-7-8-18-16(10-13)20(22)25-11-24-18;1-12-9-14(21)5-6-15(12)19-16(3-2-8-23-19)13-4-7-18-17(10-13)20(22)25-11-24-18;1-12-4-6-14(21)10-16(12)19-15(3-2-8-23-19)13-5-7-18-17(9-13)20(22)25-11-24-18/h2-10H,1H3,(H2,23,25,26);4*2-11H,1H3,(H2,22,24,25).
What are the key properties of 6-[2-(5-chloro-2-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine?
6-[2-(5-chloro-2-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine has a molecular weight of 1702.73 g/mol, XLogP of 23.11, 10 rotatable bonds, 5 hydrogen bond donors, and 20 hydrogen bond acceptors.
Where does this data come from?
All data for 6-[2-(5-chloro-2-fluoro-3-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-chloro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(3-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(4-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine;6-[2-(5-fluoro-2-methylphenyl)-3-pyridinyl]quinazolin-4-amine is sourced from PubChem (CID 158738013), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).