5-chloro-2-fluoro-4-[[(1S,2S)-2-[(3R)-3-hydroxypyrrolidin-1-yl]cyclohexyl]amino]-N-(1,3-thiazol-2-yl)benzenesulfonamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]acetamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]-N-methylacetamide;(1S,2S,4R)-1-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;(1S,2S,4R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-cyclopropyl-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-[5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)-2-(trifluoromethyl)phenoxy]-N,N-dimethylcyclohexan-1-amine

C137H169Cl5F16N24O18S13 — CID 158738800

About 5-chloro-2-fluoro-4-[[(1S,2S)-2-[(3R)-3-hydroxypyrrolidin-1-yl]cyclohexyl]amino]-N-(1,3-thiazol-2-yl)benzenesulfonamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]acetamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]-N-methylacetamide;(1S,2S,4R)-1-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;(1S,2S,4R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-cyclopropyl-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-[5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)-2-(trifluoromethyl)phenoxy]-N,N-dimethylcyclohexan-1-amine

5-chloro-2-fluoro-4-[[(1S,2S)-2-[(3R)-3-hydroxypyrrolidin-1-yl]cyclohexyl]amino]-N-(1,3-thiazol-2-yl)benzenesulfonamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]acetamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]-N-methylacetamide;(1S,2S,4R)-1-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;(1S,2S,4R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-cyclopropyl-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-[5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)-2-(trifluoromethyl)phenoxy]-N,N-dimethylcyclohexan-1-amine (PubChem CID 158738800) has the molecular formula C137H169Cl5F16N24O18S13 and a molecular weight of 3338.11 g/mol. Its IUPAC name is 5-chloro-2-fluoro-4-[[(1S,2S)-2-[(3R)-3-hydroxypyrrolidin-1-yl]cyclohexyl]amino]-N-(1,3-thiazol-2-yl)benzenesulfonamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]acetamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]-N-methylacetamide;(1S,2S,4R)-1-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;(1S,2S,4R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-cyclopropyl-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-[5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)-2-(trifluoromethyl)phenoxy]-N,N-dimethylcyclohexan-1-amine.

Molecular Properties

• Compound Name: 5-chloro-2-fluoro-4-[[(1S,2S)-2-[(3R)-3-hydroxypyrrolidin-1-yl]cyclohexyl]amino]-N-(1,3-thiazol-2-yl)benzenesulfonamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]acetamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]-N-methylacetamide;(1S,2S,4R)-1-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;(1S,2S,4R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-cyclopropyl-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-[5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)-2-(trifluoromethyl)phenoxy]-N,N-dimethylcyclohexan-1-amine
• PubChem CID: 158738800
• Molecular Formula: C137H169Cl5F16N24O18S13
• Molecular Weight: 3338.11 g/mol
• Exact Mass: 3332.76
• IUPAC Name: 5-chloro-2-fluoro-4-[[(1S,2S)-2-[(3R)-3-hydroxypyrrolidin-1-yl]cyclohexyl]amino]-N-(1,3-thiazol-2-yl)benzenesulfonamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]acetamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]-N-methylacetamide;(1S,2S,4R)-1-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;(1S,2S,4R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-cyclopropyl-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-[5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)-2-(trifluoromethyl)phenoxy]-N,N-dimethylcyclohexan-1-amine
• SMILES: CN(C)[C@H]1CCCC[C@@H]1Nc1cc(F)c(S(=O)(=O)Cc2ccncn2)cc1C1CC1.CN(C)[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Cc2nccs2)cc1C(F)(F)F.CN(C)[C@H]1CC[C@@H](C(F)(F)F)C[C@@H]1Nc1cc(F)c(S(=O)(=O)Cc2nccs2)cc1Cl.CN(C)[C@H]1C[C@H](C(F)(F)F)CC[C@@H]1Nc1cc(F)c(S(=O)(=O)Cc2nccs2)cc1Cl.CN(CC(N)=O)[C@H]1CCCC[C@@H]1Nc1cc(F)c(S(=O)(=O)Cc2nccs2)cc1Cl.CNC(=O)CN(C)[C@H]1CCCC[C@@H]1Nc1cc(F)c(S(=O)(=O)Cc2nccs2)cc1Cl.O=S(=O)(Nc1nccs1)c1cc(Cl)c(N[C@H]2CCCC[C@@H]2N2CC[C@@H](O)C2)cc1F
• InChI: InChI=1S/C22H29FN4O2S.C20H26ClFN4O3S2.2C19H22ClF4N3O2S2.2C19H24ClFN4O3S2.C19H22F4N2O3S2/c1-27(2)21-6-4-3-5-19(21)26-20-12-18(23)22(11-17(20)15-7-8-15)30(28,29)13-16-9-10-24-14-25-16;1-23-19(27)11-26(2)17-6-4-3-5-15(17)25-16-10-14(22)18(9-13(16)21)31(28,29)12-20-24-7-8-30-20;1-27(2)16-4-3-11(19(22,23)24)7-15(16)26-14-9-13(21)17(8-12(14)20)31(28,29)10-18-25-5-6-30-18;1-27(2)16-7-11(19(22,23)24)3-4-14(16)26-15-9-13(21)17(8-12(15)20)31(28,29)10-18-25-5-6-30-18;20-13-9-18(30(27,28)24-19-22-6-8-29-19)14(21)10-16(13)23-15-3-1-2-4-17(15)25-7-5-12(26)11-25;1-25(10-18(22)26)16-5-3-2-4-14(16)24-15-9-13(21)17(8-12(15)20)30(27,28)11-19-23-6-7-29-19;1-25(2)14-5-3-4-6-15(14)28-16-10-13(20)17(9-12(16)19(21,22)23)30(26,27)11-18-24-7-8-29-18/h9-12,14-15,19,21,26H,3-8,13H2,1-2H3;7-10,15,17,25H,3-6,11-12H2,1-2H3,(H,23,27);5-6,8-9,11,15-16,26H,3-4,7,10H2,1-2H3;5-6,8-9,11,14,16,26H,3-4,7,10H2,1-2H3;6,8-10,12,15,17,23,26H,1-5,7,11H2,(H,22,24);6-9,14,16,24H,2-5,10-11H2,1H3,(H2,22,26);7-10,14-15H,3-6,11H2,1-2H3/t19-,21-;15-,17-;11-,15+,16+;11-,14+,16+;12-,15+,17+;14-,16-;14-,15-/m0011100/s1
• InChIKey: IMADXAWXSPPAHD-DTNRWDBMSA-N
• XLogP: 28.13
• TPSA: 550.64 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 45
• Rotatable Bonds: 47
• Heavy Atoms: 213
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3338.11
LogP ≤ 5	28.13
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	45

Frequently Asked Questions

What is the IUPAC name of 5-chloro-2-fluoro-4-[[(1S,2S)-2-[(3R)-3-hydroxypyrrolidin-1-yl]cyclohexyl]amino]-N-(1,3-thiazol-2-yl)benzenesulfonamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]acetamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]-N-methylacetamide;(1S,2S,4R)-1-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;(1S,2S,4R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-cyclopropyl-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-[5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)-2-(trifluoromethyl)phenoxy]-N,N-dimethylcyclohexan-1-amine?

The IUPAC name of 5-chloro-2-fluoro-4-[[(1S,2S)-2-[(3R)-3-hydroxypyrrolidin-1-yl]cyclohexyl]amino]-N-(1,3-thiazol-2-yl)benzenesulfonamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]acetamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]-N-methylacetamide;(1S,2S,4R)-1-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;(1S,2S,4R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-cyclopropyl-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-[5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)-2-(trifluoromethyl)phenoxy]-N,N-dimethylcyclohexan-1-amine (CID 158738800) is 5-chloro-2-fluoro-4-[[(1S,2S)-2-[(3R)-3-hydroxypyrrolidin-1-yl]cyclohexyl]amino]-N-(1,3-thiazol-2-yl)benzenesulfonamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]acetamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]-N-methylacetamide;(1S,2S,4R)-1-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;(1S,2S,4R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-cyclopropyl-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-[5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)-2-(trifluoromethyl)phenoxy]-N,N-dimethylcyclohexan-1-amine.

What is the SMILES notation for 5-chloro-2-fluoro-4-[[(1S,2S)-2-[(3R)-3-hydroxypyrrolidin-1-yl]cyclohexyl]amino]-N-(1,3-thiazol-2-yl)benzenesulfonamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]acetamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]-N-methylacetamide;(1S,2S,4R)-1-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;(1S,2S,4R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-cyclopropyl-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-[5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)-2-(trifluoromethyl)phenoxy]-N,N-dimethylcyclohexan-1-amine?

The canonical SMILES for 5-chloro-2-fluoro-4-[[(1S,2S)-2-[(3R)-3-hydroxypyrrolidin-1-yl]cyclohexyl]amino]-N-(1,3-thiazol-2-yl)benzenesulfonamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]acetamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]-N-methylacetamide;(1S,2S,4R)-1-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;(1S,2S,4R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-cyclopropyl-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-[5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)-2-(trifluoromethyl)phenoxy]-N,N-dimethylcyclohexan-1-amine is CN(C)[C@H]1CCCC[C@@H]1Nc1cc(F)c(S(=O)(=O)Cc2ccncn2)cc1C1CC1.CN(C)[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Cc2nccs2)cc1C(F)(F)F.CN(C)[C@H]1CC[C@@H](C(F)(F)F)C[C@@H]1Nc1cc(F)c(S(=O)(=O)Cc2nccs2)cc1Cl.CN(C)[C@H]1C[C@H](C(F)(F)F)CC[C@@H]1Nc1cc(F)c(S(=O)(=O)Cc2nccs2)cc1Cl.CN(CC(N)=O)[C@H]1CCCC[C@@H]1Nc1cc(F)c(S(=O)(=O)Cc2nccs2)cc1Cl.CNC(=O)CN(C)[C@H]1CCCC[C@@H]1Nc1cc(F)c(S(=O)(=O)Cc2nccs2)cc1Cl.O=S(=O)(Nc1nccs1)c1cc(Cl)c(N[C@H]2CCCC[C@@H]2N2CC[C@@H](O)C2)cc1F.

What is the InChIKey of 5-chloro-2-fluoro-4-[[(1S,2S)-2-[(3R)-3-hydroxypyrrolidin-1-yl]cyclohexyl]amino]-N-(1,3-thiazol-2-yl)benzenesulfonamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]acetamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]-N-methylacetamide;(1S,2S,4R)-1-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;(1S,2S,4R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-cyclopropyl-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-[5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)-2-(trifluoromethyl)phenoxy]-N,N-dimethylcyclohexan-1-amine?

The InChIKey is IMADXAWXSPPAHD-DTNRWDBMSA-N. The full InChI is InChI=1S/C22H29FN4O2S.C20H26ClFN4O3S2.2C19H22ClF4N3O2S2.2C19H24ClFN4O3S2.C19H22F4N2O3S2/c1-27(2)21-6-4-3-5-19(21)26-20-12-18(23)22(11-17(20)15-7-8-15)30(28,29)13-16-9-10-24-14-25-16;1-23-19(27)11-26(2)17-6-4-3-5-15(17)25-16-10-14(22)18(9-13(16)21)31(28,29)12-20-24-7-8-30-20;1-27(2)16-4-3-11(19(22,23)24)7-15(16)26-14-9-13(21)17(8-12(14)20)31(28,29)10-18-25-5-6-30-18;1-27(2)16-7-11(19(22,23)24)3-4-14(16)26-15-9-13(21)17(8-12(15)20)31(28,29)10-18-25-5-6-30-18;20-13-9-18(30(27,28)24-19-22-6-8-29-19)14(21)10-16(13)23-15-3-1-2-4-17(15)25-7-5-12(26)11-25;1-25(10-18(22)26)16-5-3-2-4-14(16)24-15-9-13(21)17(8-12(15)20)30(27,28)11-19-23-6-7-29-19;1-25(2)14-5-3-4-6-15(14)28-16-10-13(20)17(9-12(16)19(21,22)23)30(26,27)11-18-24-7-8-29-18/h9-12,14-15,19,21,26H,3-8,13H2,1-2H3;7-10,15,17,25H,3-6,11-12H2,1-2H3,(H,23,27);5-6,8-9,11,15-16,26H,3-4,7,10H2,1-2H3;5-6,8-9,11,14,16,26H,3-4,7,10H2,1-2H3;6,8-10,12,15,17,23,26H,1-5,7,11H2,(H,22,24);6-9,14,16,24H,2-5,10-11H2,1H3,(H2,22,26);7-10,14-15H,3-6,11H2,1-2H3/t19-,21-;15-,17-;11-,15+,16+;11-,14+,16+;12-,15+,17+;14-,16-;14-,15-/m0011100/s1.

What are the key properties of 5-chloro-2-fluoro-4-[[(1S,2S)-2-[(3R)-3-hydroxypyrrolidin-1-yl]cyclohexyl]amino]-N-(1,3-thiazol-2-yl)benzenesulfonamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]acetamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]-N-methylacetamide;(1S,2S,4R)-1-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;(1S,2S,4R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-cyclopropyl-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-[5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)-2-(trifluoromethyl)phenoxy]-N,N-dimethylcyclohexan-1-amine?

5-chloro-2-fluoro-4-[[(1S,2S)-2-[(3R)-3-hydroxypyrrolidin-1-yl]cyclohexyl]amino]-N-(1,3-thiazol-2-yl)benzenesulfonamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]acetamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]-N-methylacetamide;(1S,2S,4R)-1-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;(1S,2S,4R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-cyclopropyl-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-[5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)-2-(trifluoromethyl)phenoxy]-N,N-dimethylcyclohexan-1-amine has a molecular weight of 3338.11 g/mol, XLogP of 28.13, 47 rotatable bonds, 10 hydrogen bond donors, and 45 hydrogen bond acceptors.

Where does this data come from?

All data for 5-chloro-2-fluoro-4-[[(1S,2S)-2-[(3R)-3-hydroxypyrrolidin-1-yl]cyclohexyl]amino]-N-(1,3-thiazol-2-yl)benzenesulfonamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]acetamide;2-[[(1S,2S)-2-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)anilino]cyclohexyl]-methylamino]-N-methylacetamide;(1S,2S,4R)-1-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;(1S,2S,4R)-2-N-[2-chloro-5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)phenyl]-1-N,1-N-dimethyl-4-(trifluoromethyl)cyclohexane-1,2-diamine;trans-(1S,2S)-1-N-[2-cyclopropyl-5-fluoro-4-(pyrimidin-4-ylmethylsulfonyl)phenyl]-2-N,2-N-dimethylcyclohexane-1,2-diamine;trans-(1S,2S)-2-[5-fluoro-4-(1,3-thiazol-2-ylmethylsulfonyl)-2-(trifluoromethyl)phenoxy]-N,N-dimethylcyclohexan-1-amine is sourced from PubChem (CID 158738800), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).