N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyrimidine-5-carboxamide;2-hydroxy-1-[2-[2-(1-naphthalen-2-ylsulfonylpiperidin-4-yl)ethyl]pyrimidin-5-yl]ethanone;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-3-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyrimidine-5-carboxamide

C86H92N18O16S4 — CID 158751237

IUPACN-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyrimidine-5-carboxamide;2-hydroxy-1-[2-[2-(1-naphthalen-2-ylsulfonylpiperidin-4-yl)ethyl]pyrimidin-5-yl]ethanone;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-3-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyrimidine-5-carboxamide
SMILESO=C(CO)c1cnc(CCC2CCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)nc1.O=C(NO)c1cnc(NC2CCN(S(=O)(=O)c3ccc(-c4ccccc4)cc3)CC2)nc1.O=C(NO)c1cnc(NC2CCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)nc1.O=C(NO)c1cnc(NCC2CCCN(S(=O)(=O)c3ccc4ccccc4c3)C2)nc1
InChIInChI=1S/C23H25N3O4S.C22H23N5O4S.C21H23N5O4S.C20H21N5O4S/c27-16-22(28)20-14-24-23(25-15-20)8-5-17-9-11-26(12-10-17)31(29,30)21-7-6-18-3-1-2-4-19(18)13-21;28-21(26-29)18-14-23-22(24-15-18)25-19-10-12-27(13-11-19)32(30,31)20-8-6-17(7-9-20)16-4-2-1-3-5-16;27-20(25-28)18-12-23-21(24-13-18)22-11-15-4-3-9-26(14-15)31(29,30)19-8-7-16-5-1-2-6-17(16)10-19;26-19(24-27)16-12-21-20(22-13-16)23-17-7-9-25(10-8-17)30(28,29)18-6-5-14-3-1-2-4-15(14)11-18/h1-4,6-7,13-15,17,27H,5,8-12,16H2;1-9,14-15,19,29H,10-13H2,(H,26,28)(H,23,24,25);1-2,5-8,10,12-13,15,28H,3-4,9,11,14H2,(H,25,27)(H,22,23,24);1-6,11-13,17,27H,7-10H2,(H,24,26)(H,21,22,23)
InChIKeyINMUVLNSBAYOOY-UHFFFAOYSA-N
MW1762.06 g/mol
LogP9.64
Rot. Bonds24

About N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyrimidine-5-carboxamide;2-hydroxy-1-[2-[2-(1-naphthalen-2-ylsulfonylpiperidin-4-yl)ethyl]pyrimidin-5-yl]ethanone;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-3-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyrimidine-5-carboxamide

N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyrimidine-5-carboxamide;2-hydroxy-1-[2-[2-(1-naphthalen-2-ylsulfonylpiperidin-4-yl)ethyl]pyrimidin-5-yl]ethanone;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-3-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyrimidine-5-carboxamide (PubChem CID 158751237) has the molecular formula C86H92N18O16S4 and a molecular weight of 1762.06 g/mol. Its IUPAC name is N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyrimidine-5-carboxamide;2-hydroxy-1-[2-[2-(1-naphthalen-2-ylsulfonylpiperidin-4-yl)ethyl]pyrimidin-5-yl]ethanone;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-3-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyrimidine-5-carboxamide.

Molecular Properties

Compound NameN-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyrimidine-5-carboxamide;2-hydroxy-1-[2-[2-(1-naphthalen-2-ylsulfonylpiperidin-4-yl)ethyl]pyrimidin-5-yl]ethanone;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-3-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyrimidine-5-carboxamide
PubChem CID158751237
Molecular FormulaC86H92N18O16S4
Molecular Weight1762.06 g/mol
Exact Mass1760.58
IUPAC NameN-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyrimidine-5-carboxamide;2-hydroxy-1-[2-[2-(1-naphthalen-2-ylsulfonylpiperidin-4-yl)ethyl]pyrimidin-5-yl]ethanone;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-3-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyrimidine-5-carboxamide
SMILESO=C(CO)c1cnc(CCC2CCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)nc1.O=C(NO)c1cnc(NC2CCN(S(=O)(=O)c3ccc(-c4ccccc4)cc3)CC2)nc1.O=C(NO)c1cnc(NC2CCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)nc1.O=C(NO)c1cnc(NCC2CCCN(S(=O)(=O)c3ccc4ccccc4c3)C2)nc1
InChIInChI=1S/C23H25N3O4S.C22H23N5O4S.C21H23N5O4S.C20H21N5O4S/c27-16-22(28)20-14-24-23(25-15-20)8-5-17-9-11-26(12-10-17)31(29,30)21-7-6-18-3-1-2-4-19(18)13-21;28-21(26-29)18-14-23-22(24-15-18)25-19-10-12-27(13-11-19)32(30,31)20-8-6-17(7-9-20)16-4-2-1-3-5-16;27-20(25-28)18-12-23-21(24-13-18)22-11-15-4-3-9-26(14-15)31(29,30)19-8-7-16-5-1-2-6-17(16)10-19;26-19(24-27)16-12-21-20(22-13-16)23-17-7-9-25(10-8-17)30(28,29)18-6-5-14-3-1-2-4-15(14)11-18/h1-4,6-7,13-15,17,27H,5,8-12,16H2;1-9,14-15,19,29H,10-13H2,(H,26,28)(H,23,24,25);1-2,5-8,10,12-13,15,28H,3-4,9,11,14H2,(H,25,27)(H,22,23,24);1-6,11-13,17,27H,7-10H2,(H,24,26)(H,21,22,23)
InChIKeyINMUVLNSBAYOOY-UHFFFAOYSA-N
XLogP9.64
TPSA474.02 Ų
H-Bond Donors10
H-Bond Acceptors27
Rotatable Bonds24
Heavy Atoms124
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001762.06
LogP ≤ 59.64
H-Bond Donors ≤ 510
H-Bond Acceptors ≤ 1027

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'hydroxamic_acid', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}

Analyze N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyrimidine-5-carboxamide;2-hydroxy-1-[2-[2-(1-naphthalen-2-ylsulfonylpiperidin-4-yl)ethyl]pyrimidin-5-yl]ethanone;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-3-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyrimidine-5-carboxamide with MolForge

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Related Compounds

1-[2-[[1-(benzenesulfonyl)-4-phenylpiperidin-4-yl]methyl]pyrimidin-5-yl]-2-hydroxyethanone;N-(2,6-difluorophenyl)-4-[[5-(2-hydroxyacetyl)pyrimidin-2-yl]methyl]-4-phenylpiperidine-1-carboxamide;2-hydroxy-1-[2-[[1-(4-methylphenyl)sulfonyl-4-phenylpiperidin-4-yl]methyl]pyrimidin-5-yl]ethanone;2-hydroxy-1-[2-[[4-phenyl-1-[4-(trifluoromethyl)phenyl]sulfonylpiperidin-4-yl]methyl]pyrimidin-5-yl]ethanone
CID 160343102
N-[1-[5-(2-hydroxyacetyl)pyrimidin-2-yl]piperidin-4-yl]naphthalene-2-sulfonamide
CID 148690065
Ethyl 2-[[1-(4-methylphenyl)sulfonyl-4-phenylpiperidin-4-yl]methyl]pyrimidine-5-carboxylate;ethyl 2-[(4-phenylpiperidin-4-yl)methyl]pyrimidine-5-carboxylate;2-hydroxy-1-[2-[[1-(4-methylphenyl)sulfonyl-4-phenylpiperidin-4-yl]methyl]pyrimidin-5-yl]ethanone
CID 157305466
1-[2-[[1-(Benzenesulfonyl)-4-phenylpiperidin-4-yl]methyl]pyrimidin-5-yl]-2-hydroxyethanone;ethyl 2-[[1-(benzenesulfonyl)-4-phenylpiperidin-4-yl]methyl]pyrimidine-5-carboxylate;ethyl 2-[(4-phenylpiperidin-4-yl)methyl]pyrimidine-5-carboxylate
CID 157365194
1-fluoro-2-hydroperoxyethyne;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylazepan-4-yl)amino]pyrimidine-5-carboxamide;N-hydroxy-6-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyridine-3-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyrimidine-5-carboxamide;2-hydroxy-1-[2-[2-(1-naphthalen-2-ylsulfonylpiperidin-4-yl)ethyl]pyrimidin-5-yl]ethanone;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyrimidine-5-carboxamide;N-methyl-6-[(1-naphthalen-2-ylsulfonylazepan-4-yl)amino]pyridine-3-carboxamide;N-methyl-2-[[1-(4-phenylphenyl)sulfonylazepan-4-yl]amino]pyrimidine-5-carboxamide;dihydrofluoride
CID 157596196
2-[4-benzyl-3-[(naphthalen-2-ylsulfonylamino)methyl]piperazin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[3-[(naphthalen-2-ylsulfonylamino)methyl]piperazin-1-yl]pyrimidine-5-carboxamide;bis(N-hydroxy-2-[(2S)-2-[[(4-phenylphenyl)sulfonylamino]methyl]morpholin-4-yl]pyrimidine-5-carboxamide)
CID 158430108
6-[(1-benzhydrylazetidin-3-yl)amino]-N-hydroxypyridine-3-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyrimidine-5-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-3-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyrimidine-5-carboxamide
CID 158647466
N-hydroxy-2-[4-methyl-3-[(naphthalen-2-ylsulfonylamino)methyl]piperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-6-[2-[(naphthalen-2-ylsulfonylamino)methyl]morpholin-4-yl]pyridine-3-carboxamide;N-hydroxy-2-[2-[(naphthalen-2-ylsulfonylamino)methyl]morpholin-4-yl]pyrimidine-5-carboxamide;N-hydroxy-6-[2-[[(4-phenylphenyl)sulfonylamino]methyl]morpholin-4-yl]pyridine-3-carboxamide;N-hydroxy-2-[2-[[(4-phenylphenyl)sulfonylamino]methyl]morpholin-4-yl]pyrimidine-5-carboxamide
CID 158716915
2-[4-benzyl-3-[(naphthalen-2-ylsulfonylamino)methyl]piperazin-1-yl]-N-hydroxypyrimidine-5-carboxamide;N-hydroxy-2-[4-methyl-3-[(naphthalen-2-ylsulfonylamino)methyl]piperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-2-[3-[(naphthalen-2-ylsulfonylamino)methyl]piperazin-1-yl]pyrimidine-5-carboxamide;N-hydroxy-6-[2-[[(4-phenylphenyl)sulfonylamino]methyl]morpholin-4-yl]pyridine-3-carboxamide;bis(N-hydroxy-2-[(2S)-2-[[(4-phenylphenyl)sulfonylamino]methyl]morpholin-4-yl]pyrimidine-5-carboxamide);N-hydroxy-2-[2-[[(4-phenylphenyl)sulfonylamino]methyl]morpholin-4-yl]pyrimidine-5-carboxamide
CID 158953037
N-hydroxy-2-[(1-naphthalen-2-ylsulfonylazepan-4-yl)amino]pyrimidine-5-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyrimidine-5-carboxamide;2-hydroxy-1-[2-[2-(1-naphthalen-2-ylsulfonylpiperidin-4-yl)ethyl]pyrimidin-5-yl]ethanone;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-3-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylazepan-4-yl]amino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyrimidine-5-carboxamide
CID 159046596
N-hydroxy-2-[(4-naphthalen-2-ylsulfonylmorpholin-2-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-3-yl)methylamino]pyrimidine-5-carboxamide
CID 159346140
N-hydroxy-6-[(1-naphthalen-2-ylsulfonylazepan-4-yl)amino]pyridine-3-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylazepan-4-yl)amino]pyrimidine-5-carboxamide;N-hydroxy-6-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyridine-3-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyrimidine-5-carboxamide;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylazepan-4-yl]amino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyrimidine-5-carboxamide
CID 159490108

Frequently Asked Questions

What is the IUPAC name of N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyrimidine-5-carboxamide;2-hydroxy-1-[2-[2-(1-naphthalen-2-ylsulfonylpiperidin-4-yl)ethyl]pyrimidin-5-yl]ethanone;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-3-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyrimidine-5-carboxamide?
The IUPAC name of N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyrimidine-5-carboxamide;2-hydroxy-1-[2-[2-(1-naphthalen-2-ylsulfonylpiperidin-4-yl)ethyl]pyrimidin-5-yl]ethanone;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-3-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyrimidine-5-carboxamide (CID 158751237) is N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyrimidine-5-carboxamide;2-hydroxy-1-[2-[2-(1-naphthalen-2-ylsulfonylpiperidin-4-yl)ethyl]pyrimidin-5-yl]ethanone;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-3-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyrimidine-5-carboxamide.
What is the SMILES notation for N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyrimidine-5-carboxamide;2-hydroxy-1-[2-[2-(1-naphthalen-2-ylsulfonylpiperidin-4-yl)ethyl]pyrimidin-5-yl]ethanone;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-3-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyrimidine-5-carboxamide?
The canonical SMILES for N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyrimidine-5-carboxamide;2-hydroxy-1-[2-[2-(1-naphthalen-2-ylsulfonylpiperidin-4-yl)ethyl]pyrimidin-5-yl]ethanone;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-3-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyrimidine-5-carboxamide is O=C(CO)c1cnc(CCC2CCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)nc1.O=C(NO)c1cnc(NC2CCN(S(=O)(=O)c3ccc(-c4ccccc4)cc3)CC2)nc1.O=C(NO)c1cnc(NC2CCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)nc1.O=C(NO)c1cnc(NCC2CCCN(S(=O)(=O)c3ccc4ccccc4c3)C2)nc1.
What is the InChIKey of N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyrimidine-5-carboxamide;2-hydroxy-1-[2-[2-(1-naphthalen-2-ylsulfonylpiperidin-4-yl)ethyl]pyrimidin-5-yl]ethanone;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-3-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyrimidine-5-carboxamide?
The InChIKey is INMUVLNSBAYOOY-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H25N3O4S.C22H23N5O4S.C21H23N5O4S.C20H21N5O4S/c27-16-22(28)20-14-24-23(25-15-20)8-5-17-9-11-26(12-10-17)31(29,30)21-7-6-18-3-1-2-4-19(18)13-21;28-21(26-29)18-14-23-22(24-15-18)25-19-10-12-27(13-11-19)32(30,31)20-8-6-17(7-9-20)16-4-2-1-3-5-16;27-20(25-28)18-12-23-21(24-13-18)22-11-15-4-3-9-26(14-15)31(29,30)19-8-7-16-5-1-2-6-17(16)10-19;26-19(24-27)16-12-21-20(22-13-16)23-17-7-9-25(10-8-17)30(28,29)18-6-5-14-3-1-2-4-15(14)11-18/h1-4,6-7,13-15,17,27H,5,8-12,16H2;1-9,14-15,19,29H,10-13H2,(H,26,28)(H,23,24,25);1-2,5-8,10,12-13,15,28H,3-4,9,11,14H2,(H,25,27)(H,22,23,24);1-6,11-13,17,27H,7-10H2,(H,24,26)(H,21,22,23).
What are the key properties of N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyrimidine-5-carboxamide;2-hydroxy-1-[2-[2-(1-naphthalen-2-ylsulfonylpiperidin-4-yl)ethyl]pyrimidin-5-yl]ethanone;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-3-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyrimidine-5-carboxamide?
N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyrimidine-5-carboxamide;2-hydroxy-1-[2-[2-(1-naphthalen-2-ylsulfonylpiperidin-4-yl)ethyl]pyrimidin-5-yl]ethanone;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-3-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyrimidine-5-carboxamide has a molecular weight of 1762.06 g/mol, XLogP of 9.64, 24 rotatable bonds, 10 hydrogen bond donors, and 27 hydrogen bond acceptors.
Where does this data come from?
All data for N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-4-yl)amino]pyrimidine-5-carboxamide;2-hydroxy-1-[2-[2-(1-naphthalen-2-ylsulfonylpiperidin-4-yl)ethyl]pyrimidin-5-yl]ethanone;N-hydroxy-2-[(1-naphthalen-2-ylsulfonylpiperidin-3-yl)methylamino]pyrimidine-5-carboxamide;N-hydroxy-2-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyrimidine-5-carboxamide is sourced from PubChem (CID 158751237), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).