N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(2,2-dimethylpropoxy)pyrazol-1-yl]-2-(7-methyl-5-azaspiro[3.4]octan-5-yl)pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(trifluoromethyl)phenyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(3,4-dihydro-2H-chromen-3-ylmethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide

C80H93F3N16O12S3 — CID 158757802

About N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(2,2-dimethylpropoxy)pyrazol-1-yl]-2-(7-methyl-5-azaspiro[3.4]octan-5-yl)pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(trifluoromethyl)phenyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(3,4-dihydro-2H-chromen-3-ylmethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide

N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(2,2-dimethylpropoxy)pyrazol-1-yl]-2-(7-methyl-5-azaspiro[3.4]octan-5-yl)pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(trifluoromethyl)phenyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(3,4-dihydro-2H-chromen-3-ylmethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide (PubChem CID 158757802) has the molecular formula C80H93F3N16O12S3 and a molecular weight of 1623.92 g/mol. Its IUPAC name is N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(2,2-dimethylpropoxy)pyrazol-1-yl]-2-(7-methyl-5-azaspiro[3.4]octan-5-yl)pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(trifluoromethyl)phenyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(3,4-dihydro-2H-chromen-3-ylmethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide.

Molecular Properties

• Compound Name: N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(2,2-dimethylpropoxy)pyrazol-1-yl]-2-(7-methyl-5-azaspiro[3.4]octan-5-yl)pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(trifluoromethyl)phenyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(3,4-dihydro-2H-chromen-3-ylmethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide
• PubChem CID: 158757802
• Molecular Formula: C80H93F3N16O12S3
• Molecular Weight: 1623.92 g/mol
• Exact Mass: 1622.63
• IUPAC Name: N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(2,2-dimethylpropoxy)pyrazol-1-yl]-2-(7-methyl-5-azaspiro[3.4]octan-5-yl)pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(trifluoromethyl)phenyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(3,4-dihydro-2H-chromen-3-ylmethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide
• SMILES: CC1CN(c2nc(-n3ccc(OCC(C)(C)C)n3)ccc2C(=O)NS(=O)(=O)c2cccnc2N)C2(CCC2)C1.CC1CN(c2ncccc2C(=O)NS(=O)(=O)c2cccc(OCC3COc4ccccc4C3)n2)C(C)(C)C1.C[C@@H]1CN(c2nc(-c3cccc(C(F)(F)F)c3)ccc2C(=O)NS(=O)(=O)c2cccnc2N)C(C)(C)C1
• InChI: InChI=1S/C28H32N4O5S.C27H35N7O4S.C25H26F3N5O3S/c1-19-15-28(2,3)32(16-19)26-22(9-7-13-29-26)27(33)31-38(34,35)25-12-6-11-24(30-25)37-18-20-14-21-8-4-5-10-23(21)36-17-20;1-18-15-27(11-6-12-27)33(16-18)24-19(25(35)32-39(36,37)20-7-5-13-29-23(20)28)8-9-21(30-24)34-14-10-22(31-34)38-17-26(2,3)4;1-15-13-24(2,3)33(14-15)22-18(23(34)32-37(35,36)20-8-5-11-30-21(20)29)9-10-19(31-22)16-6-4-7-17(12-16)25(26,27)28/h4-13,19-20H,14-18H2,1-3H3,(H,31,33);5,7-10,13-14,18H,6,11-12,15-17H2,1-4H3,(H2,28,29)(H,32,35);4-12,15H,13-14H2,1-3H3,(H2,29,30)(H,32,34)/t;;15-/m..0/s1
• InChIKey: IOHCUEJWAHWUJU-BDPULHTRSA-N
• XLogP: 11.90
• TPSA: 374.33 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 25
• Rotatable Bonds: 19
• Heavy Atoms: 114
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1623.92
LogP ≤ 5	11.90
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	25

Frequently Asked Questions

What is the IUPAC name of N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(2,2-dimethylpropoxy)pyrazol-1-yl]-2-(7-methyl-5-azaspiro[3.4]octan-5-yl)pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(trifluoromethyl)phenyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(3,4-dihydro-2H-chromen-3-ylmethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide?

The IUPAC name of N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(2,2-dimethylpropoxy)pyrazol-1-yl]-2-(7-methyl-5-azaspiro[3.4]octan-5-yl)pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(trifluoromethyl)phenyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(3,4-dihydro-2H-chromen-3-ylmethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide (CID 158757802) is N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(2,2-dimethylpropoxy)pyrazol-1-yl]-2-(7-methyl-5-azaspiro[3.4]octan-5-yl)pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(trifluoromethyl)phenyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(3,4-dihydro-2H-chromen-3-ylmethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide.

What is the SMILES notation for N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(2,2-dimethylpropoxy)pyrazol-1-yl]-2-(7-methyl-5-azaspiro[3.4]octan-5-yl)pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(trifluoromethyl)phenyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(3,4-dihydro-2H-chromen-3-ylmethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide?

The canonical SMILES for N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(2,2-dimethylpropoxy)pyrazol-1-yl]-2-(7-methyl-5-azaspiro[3.4]octan-5-yl)pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(trifluoromethyl)phenyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(3,4-dihydro-2H-chromen-3-ylmethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide is CC1CN(c2nc(-n3ccc(OCC(C)(C)C)n3)ccc2C(=O)NS(=O)(=O)c2cccnc2N)C2(CCC2)C1.CC1CN(c2ncccc2C(=O)NS(=O)(=O)c2cccc(OCC3COc4ccccc4C3)n2)C(C)(C)C1.C[C@@H]1CN(c2nc(-c3cccc(C(F)(F)F)c3)ccc2C(=O)NS(=O)(=O)c2cccnc2N)C(C)(C)C1.

What is the InChIKey of N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(2,2-dimethylpropoxy)pyrazol-1-yl]-2-(7-methyl-5-azaspiro[3.4]octan-5-yl)pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(trifluoromethyl)phenyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(3,4-dihydro-2H-chromen-3-ylmethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide?

The InChIKey is IOHCUEJWAHWUJU-BDPULHTRSA-N. The full InChI is InChI=1S/C28H32N4O5S.C27H35N7O4S.C25H26F3N5O3S/c1-19-15-28(2,3)32(16-19)26-22(9-7-13-29-26)27(33)31-38(34,35)25-12-6-11-24(30-25)37-18-20-14-21-8-4-5-10-23(21)36-17-20;1-18-15-27(11-6-12-27)33(16-18)24-19(25(35)32-39(36,37)20-7-5-13-29-23(20)28)8-9-21(30-24)34-14-10-22(31-34)38-17-26(2,3)4;1-15-13-24(2,3)33(14-15)22-18(23(34)32-37(35,36)20-8-5-11-30-21(20)29)9-10-19(31-22)16-6-4-7-17(12-16)25(26,27)28/h4-13,19-20H,14-18H2,1-3H3,(H,31,33);5,7-10,13-14,18H,6,11-12,15-17H2,1-4H3,(H2,28,29)(H,32,35);4-12,15H,13-14H2,1-3H3,(H2,29,30)(H,32,34)/t;;15-/m..0/s1.

What are the key properties of N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(2,2-dimethylpropoxy)pyrazol-1-yl]-2-(7-methyl-5-azaspiro[3.4]octan-5-yl)pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(trifluoromethyl)phenyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(3,4-dihydro-2H-chromen-3-ylmethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide?

N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(2,2-dimethylpropoxy)pyrazol-1-yl]-2-(7-methyl-5-azaspiro[3.4]octan-5-yl)pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(trifluoromethyl)phenyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(3,4-dihydro-2H-chromen-3-ylmethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide has a molecular weight of 1623.92 g/mol, XLogP of 11.90, 19 rotatable bonds, 5 hydrogen bond donors, and 25 hydrogen bond acceptors.

Where does this data come from?

All data for N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(2,2-dimethylpropoxy)pyrazol-1-yl]-2-(7-methyl-5-azaspiro[3.4]octan-5-yl)pyridine-3-carboxamide;N-[(2-amino-3-pyridinyl)sulfonyl]-6-[3-(trifluoromethyl)phenyl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide;N-[[6-(3,4-dihydro-2H-chromen-3-ylmethoxy)-2-pyridinyl]sulfonyl]-2-(2,2,4-trimethylpyrrolidin-1-yl)pyridine-3-carboxamide is sourced from PubChem (CID 158757802), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).