(4-benzylpiperidin-1-yl)-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;[5-[5-[chloro(difluoro)methyl]-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-methyl-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;[4-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;1-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carbonyl]piperidine-4-carboxamide;[5-[4-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[5-[5-(1,1,2,2,2-pentafluoroethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone

C132H137ClF25N25O9S6 — CID 158764224

About (4-benzylpiperidin-1-yl)-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;[5-[5-[chloro(difluoro)methyl]-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-methyl-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;[4-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;1-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carbonyl]piperidine-4-carboxamide;[5-[4-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[5-[5-(1,1,2,2,2-pentafluoroethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone

(4-benzylpiperidin-1-yl)-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;[5-[5-[chloro(difluoro)methyl]-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-methyl-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;[4-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;1-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carbonyl]piperidine-4-carboxamide;[5-[4-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[5-[5-(1,1,2,2,2-pentafluoroethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone (PubChem CID 158764224) has the molecular formula C132H137ClF25N25O9S6 and a molecular weight of 2920.52 g/mol. Its IUPAC name is (4-benzylpiperidin-1-yl)-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;[5-[5-[chloro(difluoro)methyl]-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-methyl-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;[4-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;1-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carbonyl]piperidine-4-carboxamide;[5-[4-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[5-[5-(1,1,2,2,2-pentafluoroethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone.

Molecular Properties

• Compound Name: (4-benzylpiperidin-1-yl)-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;[5-[5-[chloro(difluoro)methyl]-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-methyl-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;[4-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;1-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carbonyl]piperidine-4-carboxamide;[5-[4-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[5-[5-(1,1,2,2,2-pentafluoroethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone
• PubChem CID: 158764224
• Molecular Formula: C132H137ClF25N25O9S6
• Molecular Weight: 2920.52 g/mol
• Exact Mass: 2917.86
• IUPAC Name: (4-benzylpiperidin-1-yl)-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;[5-[5-[chloro(difluoro)methyl]-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-methyl-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;[4-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;1-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carbonyl]piperidine-4-carboxamide;[5-[4-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[5-[5-(1,1,2,2,2-pentafluoroethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone
• SMILES: Cc1c(-c2ccc(C(=O)N3CCCCC3)s2)n[nH]c1C(F)(F)F.Cc1cc(-c2cc(C(F)(F)F)n(C)n2)sc1C(=O)N1CCCCC1.Cn1nc(-c2ccc(C(=O)N3CCC(C(N)=O)CC3)s2)cc1C(F)(F)F.Cn1nc(-c2ccc(C(=O)N3CCC(Cc4ccccc4)CC3)s2)cc1C(F)(F)F.Cn1nc(-c2ccc(C(=O)N3CCCCC3)cc2)cc1C(F)(F)F.Cn1nc(-c2cccc(C(=O)N3CCCCC3)c2)cc1C(F)(F)F.O=C(c1ccc(-c2cc(C(F)(F)C(F)(F)F)[nH]n2)s1)N1CCCCC1.O=C(c1ccc(-c2cc(C(F)(F)Cl)[nH]n2)s1)N1CCCCC1
• InChI: InChI=1S/C22H22F3N3OS.2C17H18F3N3O.C16H17F3N4O2S.C16H18F3N3OS.C15H14F5N3OS.C15H16F3N3OS.C14H14ClF2N3OS/c1-27-20(22(23,24)25)14-17(26-27)18-7-8-19(30-18)21(29)28-11-9-16(10-12-28)13-15-5-3-2-4-6-15;1-22-15(17(18,19)20)11-14(21-22)12-5-7-13(8-6-12)16(24)23-9-3-2-4-10-23;1-22-15(17(18,19)20)11-14(21-22)12-6-5-7-13(10-12)16(24)23-8-3-2-4-9-23;1-22-13(16(17,18)19)8-10(21-22)11-2-3-12(26-11)15(25)23-6-4-9(5-7-23)14(20)24;1-10-8-12(11-9-13(16(17,18)19)21(2)20-11)24-14(10)15(23)22-6-4-3-5-7-22;16-14(17,15(18,19)20)12-8-9(21-22-12)10-4-5-11(25-10)13(24)23-6-2-1-3-7-23;1-9-12(19-20-13(9)15(16,17)18)10-5-6-11(23-10)14(22)21-7-3-2-4-8-21;15-14(16,17)12-8-9(18-19-12)10-4-5-11(22-10)13(21)20-6-2-1-3-7-20/h2-8,14,16H,9-13H2,1H3;5-8,11H,2-4,9-10H2,1H3;5-7,10-11H,2-4,8-9H2,1H3;2-3,8-9H,4-7H2,1H3,(H2,20,24);8-9H,3-7H2,1-2H3;4-5,8H,1-3,6-7H2,(H,21,22);5-6H,2-4,7-8H2,1H3,(H,19,20);4-5,8H,1-3,6-7H2,(H,18,19)
• InChIKey: IPBARNBLKYYXAX-UHFFFAOYSA-N
• XLogP: 31.90
• TPSA: 380.71 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 28
• Rotatable Bonds: 21
• Heavy Atoms: 198
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2920.52
LogP ≤ 5	31.90
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	28

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'alkyl_halide', 'substructure': 'N/A'}, {'alert_name': 'Perfluorinated_chain', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of (4-benzylpiperidin-1-yl)-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;[5-[5-[chloro(difluoro)methyl]-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-methyl-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;[4-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;1-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carbonyl]piperidine-4-carboxamide;[5-[4-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[5-[5-(1,1,2,2,2-pentafluoroethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone?

The IUPAC name of (4-benzylpiperidin-1-yl)-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;[5-[5-[chloro(difluoro)methyl]-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-methyl-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;[4-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;1-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carbonyl]piperidine-4-carboxamide;[5-[4-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[5-[5-(1,1,2,2,2-pentafluoroethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone (CID 158764224) is (4-benzylpiperidin-1-yl)-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;[5-[5-[chloro(difluoro)methyl]-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-methyl-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;[4-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;1-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carbonyl]piperidine-4-carboxamide;[5-[4-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[5-[5-(1,1,2,2,2-pentafluoroethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone.

What is the SMILES notation for (4-benzylpiperidin-1-yl)-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;[5-[5-[chloro(difluoro)methyl]-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-methyl-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;[4-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;1-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carbonyl]piperidine-4-carboxamide;[5-[4-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[5-[5-(1,1,2,2,2-pentafluoroethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone?

The canonical SMILES for (4-benzylpiperidin-1-yl)-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;[5-[5-[chloro(difluoro)methyl]-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-methyl-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;[4-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;1-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carbonyl]piperidine-4-carboxamide;[5-[4-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[5-[5-(1,1,2,2,2-pentafluoroethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone is Cc1c(-c2ccc(C(=O)N3CCCCC3)s2)n[nH]c1C(F)(F)F.Cc1cc(-c2cc(C(F)(F)F)n(C)n2)sc1C(=O)N1CCCCC1.Cn1nc(-c2ccc(C(=O)N3CCC(C(N)=O)CC3)s2)cc1C(F)(F)F.Cn1nc(-c2ccc(C(=O)N3CCC(Cc4ccccc4)CC3)s2)cc1C(F)(F)F.Cn1nc(-c2ccc(C(=O)N3CCCCC3)cc2)cc1C(F)(F)F.Cn1nc(-c2cccc(C(=O)N3CCCCC3)c2)cc1C(F)(F)F.O=C(c1ccc(-c2cc(C(F)(F)C(F)(F)F)[nH]n2)s1)N1CCCCC1.O=C(c1ccc(-c2cc(C(F)(F)Cl)[nH]n2)s1)N1CCCCC1.

What is the InChIKey of (4-benzylpiperidin-1-yl)-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;[5-[5-[chloro(difluoro)methyl]-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-methyl-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;[4-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;1-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carbonyl]piperidine-4-carboxamide;[5-[4-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[5-[5-(1,1,2,2,2-pentafluoroethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone?

The InChIKey is IPBARNBLKYYXAX-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H22F3N3OS.2C17H18F3N3O.C16H17F3N4O2S.C16H18F3N3OS.C15H14F5N3OS.C15H16F3N3OS.C14H14ClF2N3OS/c1-27-20(22(23,24)25)14-17(26-27)18-7-8-19(30-18)21(29)28-11-9-16(10-12-28)13-15-5-3-2-4-6-15;1-22-15(17(18,19)20)11-14(21-22)12-5-7-13(8-6-12)16(24)23-9-3-2-4-10-23;1-22-15(17(18,19)20)11-14(21-22)12-6-5-7-13(10-12)16(24)23-8-3-2-4-9-23;1-22-13(16(17,18)19)8-10(21-22)11-2-3-12(26-11)15(25)23-6-4-9(5-7-23)14(20)24;1-10-8-12(11-9-13(16(17,18)19)21(2)20-11)24-14(10)15(23)22-6-4-3-5-7-22;16-14(17,15(18,19)20)12-8-9(21-22-12)10-4-5-11(25-10)13(24)23-6-2-1-3-7-23;1-9-12(19-20-13(9)15(16,17)18)10-5-6-11(23-10)14(22)21-7-3-2-4-8-21;15-14(16,17)12-8-9(18-19-12)10-4-5-11(22-10)13(21)20-6-2-1-3-7-20/h2-8,14,16H,9-13H2,1H3;5-8,11H,2-4,9-10H2,1H3;5-7,10-11H,2-4,8-9H2,1H3;2-3,8-9H,4-7H2,1H3,(H2,20,24);8-9H,3-7H2,1-2H3;4-5,8H,1-3,6-7H2,(H,21,22);5-6H,2-4,7-8H2,1H3,(H,19,20);4-5,8H,1-3,6-7H2,(H,18,19).

What are the key properties of (4-benzylpiperidin-1-yl)-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;[5-[5-[chloro(difluoro)methyl]-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-methyl-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;[4-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;1-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carbonyl]piperidine-4-carboxamide;[5-[4-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[5-[5-(1,1,2,2,2-pentafluoroethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone?

(4-benzylpiperidin-1-yl)-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;[5-[5-[chloro(difluoro)methyl]-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-methyl-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;[4-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;1-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carbonyl]piperidine-4-carboxamide;[5-[4-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[5-[5-(1,1,2,2,2-pentafluoroethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone has a molecular weight of 2920.52 g/mol, XLogP of 31.90, 21 rotatable bonds, 4 hydrogen bond donors, and 28 hydrogen bond acceptors.

Where does this data come from?

All data for (4-benzylpiperidin-1-yl)-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]methanone;[5-[5-[chloro(difluoro)methyl]-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-methyl-5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[3-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;[4-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]phenyl]-piperidin-1-ylmethanone;1-[5-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carbonyl]piperidine-4-carboxamide;[5-[4-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone;[5-[5-(1,1,2,2,2-pentafluoroethyl)-1H-pyrazol-3-yl]thiophen-2-yl]-piperidin-1-ylmethanone is sourced from PubChem (CID 158764224), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).