2,6-difluoro-N-[4-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(1,3,4-oxadiazol-2-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[6-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-3-pyridinyl]benzamide;N-[4-[5-(3-ethylimidazol-4-yl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;3-methyl-N-[5-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-2-pyridinyl]pyridine-4-carboxamide;hydrochloride

C147H110ClF12N23O10S7 — CID 158775931

About 2,6-difluoro-N-[4-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(1,3,4-oxadiazol-2-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[6-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-3-pyridinyl]benzamide;N-[4-[5-(3-ethylimidazol-4-yl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;3-methyl-N-[5-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-2-pyridinyl]pyridine-4-carboxamide;hydrochloride

2,6-difluoro-N-[4-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(1,3,4-oxadiazol-2-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[6-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-3-pyridinyl]benzamide;N-[4-[5-(3-ethylimidazol-4-yl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;3-methyl-N-[5-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-2-pyridinyl]pyridine-4-carboxamide;hydrochloride (PubChem CID 158775931) has the molecular formula C147H110ClF12N23O10S7 and a molecular weight of 2846.55 g/mol. Its IUPAC name is 2,6-difluoro-N-[4-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(1,3,4-oxadiazol-2-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[6-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-3-pyridinyl]benzamide;N-[4-[5-(3-ethylimidazol-4-yl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;3-methyl-N-[5-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-2-pyridinyl]pyridine-4-carboxamide;hydrochloride.

Molecular Properties

• Compound Name: 2,6-difluoro-N-[4-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(1,3,4-oxadiazol-2-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[6-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-3-pyridinyl]benzamide;N-[4-[5-(3-ethylimidazol-4-yl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;3-methyl-N-[5-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-2-pyridinyl]pyridine-4-carboxamide;hydrochloride
• PubChem CID: 158775931
• Molecular Formula: C147H110ClF12N23O10S7
• Molecular Weight: 2846.55 g/mol
• Exact Mass: 2843.63
• IUPAC Name: 2,6-difluoro-N-[4-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(1,3,4-oxadiazol-2-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[6-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-3-pyridinyl]benzamide;N-[4-[5-(3-ethylimidazol-4-yl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;3-methyl-N-[5-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-2-pyridinyl]pyridine-4-carboxamide;hydrochloride
• SMILES: CCn1cncc1-c1cc(-c2ccc(NC(=O)c3c(F)cccc3F)cc2)c(C)s1.Cc1cnccc1C(=O)Nc1ccc(-c2cc(-c3cnco3)sc2C)cn1.Cc1sc(-c2cnc[nH]2)cc1-c1ccc(NC(=O)c2c(F)cccc2F)cc1.Cc1sc(-c2cncn2C)cc1-c1ccc(NC(=O)c2c(F)cccc2F)cc1.Cc1sc(-c2cncn2C)cc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1.Cc1sc(-c2cnco2)cc1-c1ccc(NC(=O)c2c(F)cccc2F)cn1.Cc1sc(-c2nnco2)cc1-c1ccc(NC(=O)c2c(F)cccc2F)cc1.Cl
• InChI: InChI=1S/C23H19F2N3OS.C22H17F2N3OS.C21H16F2N4OS.C21H15F2N3OS.2C20H13F2N3O2S.C20H16N4O2S.ClH/c1-3-28-13-26-12-20(28)21-11-17(14(2)30-21)15-7-9-16(10-8-15)27-23(29)22-18(24)5-4-6-19(22)25;1-13-16(10-20(29-13)19-11-25-12-27(19)2)14-6-8-15(9-7-14)26-22(28)21-17(23)4-3-5-18(21)24;1-12-14(8-18(29-12)17-10-24-11-27(17)2)13-6-7-19(25-9-13)26-21(28)20-15(22)4-3-5-16(20)23;1-12-15(9-19(28-12)18-10-24-11-25-18)13-5-7-14(8-6-13)26-21(27)20-16(22)3-2-4-17(20)23;1-11-14(9-17(28-11)20-25-23-10-27-20)12-5-7-13(8-6-12)24-19(26)18-15(21)3-2-4-16(18)22;1-11-13(7-18(28-11)17-9-23-10-27-17)16-6-5-12(8-24-16)25-20(26)19-14(21)3-2-4-15(19)22;1-12-8-21-6-5-15(12)20(25)24-19-4-3-14(9-23-19)16-7-18(27-13(16)2)17-10-22-11-26-17;/h4-13H,3H2,1-2H3,(H,27,29);3-12H,1-2H3,(H,26,28);3-11H,1-2H3,(H,25,26,28);2-11H,1H3,(H,24,25)(H,26,27);2-10H,1H3,(H,24,26);2-10H,1H3,(H,25,26);3-11H,1-2H3,(H,23,24,25);1H
• InChIKey: KWUDAFQMSLTCLD-UHFFFAOYSA-N
• XLogP: 38.24
• TPSA: 428.38 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 32
• Rotatable Bonds: 29
• Heavy Atoms: 200
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2846.55
LogP ≤ 5	38.24
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	32

Frequently Asked Questions

What is the IUPAC name of 2,6-difluoro-N-[4-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(1,3,4-oxadiazol-2-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[6-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-3-pyridinyl]benzamide;N-[4-[5-(3-ethylimidazol-4-yl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;3-methyl-N-[5-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-2-pyridinyl]pyridine-4-carboxamide;hydrochloride?

The IUPAC name of 2,6-difluoro-N-[4-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(1,3,4-oxadiazol-2-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[6-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-3-pyridinyl]benzamide;N-[4-[5-(3-ethylimidazol-4-yl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;3-methyl-N-[5-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-2-pyridinyl]pyridine-4-carboxamide;hydrochloride (CID 158775931) is 2,6-difluoro-N-[4-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(1,3,4-oxadiazol-2-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[6-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-3-pyridinyl]benzamide;N-[4-[5-(3-ethylimidazol-4-yl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;3-methyl-N-[5-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-2-pyridinyl]pyridine-4-carboxamide;hydrochloride.

What is the SMILES notation for 2,6-difluoro-N-[4-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(1,3,4-oxadiazol-2-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[6-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-3-pyridinyl]benzamide;N-[4-[5-(3-ethylimidazol-4-yl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;3-methyl-N-[5-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-2-pyridinyl]pyridine-4-carboxamide;hydrochloride?

The canonical SMILES for 2,6-difluoro-N-[4-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(1,3,4-oxadiazol-2-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[6-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-3-pyridinyl]benzamide;N-[4-[5-(3-ethylimidazol-4-yl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;3-methyl-N-[5-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-2-pyridinyl]pyridine-4-carboxamide;hydrochloride is CCn1cncc1-c1cc(-c2ccc(NC(=O)c3c(F)cccc3F)cc2)c(C)s1.Cc1cnccc1C(=O)Nc1ccc(-c2cc(-c3cnco3)sc2C)cn1.Cc1sc(-c2cnc[nH]2)cc1-c1ccc(NC(=O)c2c(F)cccc2F)cc1.Cc1sc(-c2cncn2C)cc1-c1ccc(NC(=O)c2c(F)cccc2F)cc1.Cc1sc(-c2cncn2C)cc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1.Cc1sc(-c2cnco2)cc1-c1ccc(NC(=O)c2c(F)cccc2F)cn1.Cc1sc(-c2nnco2)cc1-c1ccc(NC(=O)c2c(F)cccc2F)cc1.Cl.

What is the InChIKey of 2,6-difluoro-N-[4-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(1,3,4-oxadiazol-2-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[6-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-3-pyridinyl]benzamide;N-[4-[5-(3-ethylimidazol-4-yl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;3-methyl-N-[5-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-2-pyridinyl]pyridine-4-carboxamide;hydrochloride?

The InChIKey is KWUDAFQMSLTCLD-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H19F2N3OS.C22H17F2N3OS.C21H16F2N4OS.C21H15F2N3OS.2C20H13F2N3O2S.C20H16N4O2S.ClH/c1-3-28-13-26-12-20(28)21-11-17(14(2)30-21)15-7-9-16(10-8-15)27-23(29)22-18(24)5-4-6-19(22)25;1-13-16(10-20(29-13)19-11-25-12-27(19)2)14-6-8-15(9-7-14)26-22(28)21-17(23)4-3-5-18(21)24;1-12-14(8-18(29-12)17-10-24-11-27(17)2)13-6-7-19(25-9-13)26-21(28)20-15(22)4-3-5-16(20)23;1-12-15(9-19(28-12)18-10-24-11-25-18)13-5-7-14(8-6-13)26-21(27)20-16(22)3-2-4-17(20)23;1-11-14(9-17(28-11)20-25-23-10-27-20)12-5-7-13(8-6-12)24-19(26)18-15(21)3-2-4-16(18)22;1-11-13(7-18(28-11)17-9-23-10-27-17)16-6-5-12(8-24-16)25-20(26)19-14(21)3-2-4-15(19)22;1-12-8-21-6-5-15(12)20(25)24-19-4-3-14(9-23-19)16-7-18(27-13(16)2)17-10-22-11-26-17;/h4-13H,3H2,1-2H3,(H,27,29);3-12H,1-2H3,(H,26,28);3-11H,1-2H3,(H,25,26,28);2-11H,1H3,(H,24,25)(H,26,27);2-10H,1H3,(H,24,26);2-10H,1H3,(H,25,26);3-11H,1-2H3,(H,23,24,25);1H.

What are the key properties of 2,6-difluoro-N-[4-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(1,3,4-oxadiazol-2-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[6-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-3-pyridinyl]benzamide;N-[4-[5-(3-ethylimidazol-4-yl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;3-methyl-N-[5-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-2-pyridinyl]pyridine-4-carboxamide;hydrochloride?

2,6-difluoro-N-[4-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(1,3,4-oxadiazol-2-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[6-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-3-pyridinyl]benzamide;N-[4-[5-(3-ethylimidazol-4-yl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;3-methyl-N-[5-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-2-pyridinyl]pyridine-4-carboxamide;hydrochloride has a molecular weight of 2846.55 g/mol, XLogP of 38.24, 29 rotatable bonds, 8 hydrogen bond donors, and 32 hydrogen bond acceptors.

Where does this data come from?

All data for 2,6-difluoro-N-[4-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(1,3,4-oxadiazol-2-yl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[6-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-3-pyridinyl]benzamide;N-[4-[5-(3-ethylimidazol-4-yl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;3-methyl-N-[5-[2-methyl-5-(1,3-oxazol-5-yl)thiophen-3-yl]-2-pyridinyl]pyridine-4-carboxamide;hydrochloride is sourced from PubChem (CID 158775931), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).