6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-[6-[(3R)-1-propan-2-ylpyrrolidin-3-yl]oxy-3-pyridinyl]pyrimidin-4-amine;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]oxypiperidin-1-yl]-phenylmethanone;5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyrimidin-2-amine;5-[2-morpholin-4-yl-6-(5-piperidin-4-yloxy-3-pyridinyl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine;5-[2-morpholin-4-yl-6-[5-(1-propan-2-ylpiperidin-4-yl)oxy-3-pyridinyl]pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine

C120H136F15N35O11 — CID 158779723

IUPAC6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-[6-[(3R)-1-propan-2-ylpyrrolidin-3-yl]oxy-3-pyridinyl]pyrimidin-4-amine;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]oxypiperidin-1-yl]-phenylmethanone;5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyrimidin-2-amine;5-[2-morpholin-4-yl-6-(5-piperidin-4-yloxy-3-pyridinyl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine;5-[2-morpholin-4-yl-6-[5-(1-propan-2-ylpiperidin-4-yl)oxy-3-pyridinyl]pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine
SMILESCC(C)N1CCC(Oc2cncc(-c3cc(-c4cnc(N)cc4C(F)(F)F)nc(N4CCOCC4)n3)c2)CC1.CC(C)N1CC[C@@H](Oc2ccc(Nc3cc(-c4cnc(N)cc4C(F)(F)F)nc(N4CCOCC4)n3)cn2)C1.Nc1cc(C(F)(F)F)c(-c2cc(-c3cncc(OC4CCNCC4)c3)nc(N3CCOCC3)n2)cn1.Nc1cc(C(F)(F)F)c(-c2cc(OC3CCN(C(=O)c4ccccc4)CC3)nc(N3CCOCC3)n2)cn1.Nc1ncc(-c2cc(N3CCOCC3)nc(N3CCOCC3)n2)c(C(F)(F)F)n1
InChIInChI=1S/C27H32F3N7O2.C26H31F3N8O2.C26H27F3N6O3.C24H26F3N7O2.C17H20F3N7O2/c1-17(2)36-5-3-19(4-6-36)39-20-11-18(14-32-15-20)23-13-24(35-26(34-23)37-7-9-38-10-8-37)21-16-33-25(31)12-22(21)27(28,29)30;1-16(2)37-6-5-18(15-37)39-24-4-3-17(13-32-24)33-23-12-21(34-25(35-23)36-7-9-38-10-8-36)19-14-31-22(30)11-20(19)26(27,28)29;27-26(28,29)20-14-22(30)31-16-19(20)21-15-23(33-25(32-21)35-10-12-37-13-11-35)38-18-6-8-34(9-7-18)24(36)17-4-2-1-3-5-17;25-24(26,27)19-10-22(28)31-14-18(19)21-11-20(32-23(33-21)34-5-7-35-8-6-34)15-9-17(13-30-12-15)36-16-1-3-29-4-2-16;18-17(19,20)14-11(10-22-15(21)25-14)12-9-13(26-1-5-28-6-2-26)24-16(23-12)27-3-7-29-8-4-27/h11-17,19H,3-10H2,1-2H3,(H2,31,33);3-4,11-14,16,18H,5-10,15H2,1-2H3,(H2,30,31)(H,33,34,35);1-5,14-16,18H,6-13H2,(H2,30,31);9-14,16,29H,1-8H2,(H2,28,31);9-10H,1-8H2,(H2,21,22,25)/t;18-;;;/m.1.../s1
InChIKeyIQXOFRUGSNBZHI-OEGAAENXSA-N
MW2529.61 g/mol
LogP16.30
Rot. Bonds26

About 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-[6-[(3R)-1-propan-2-ylpyrrolidin-3-yl]oxy-3-pyridinyl]pyrimidin-4-amine;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]oxypiperidin-1-yl]-phenylmethanone;5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyrimidin-2-amine;5-[2-morpholin-4-yl-6-(5-piperidin-4-yloxy-3-pyridinyl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine;5-[2-morpholin-4-yl-6-[5-(1-propan-2-ylpiperidin-4-yl)oxy-3-pyridinyl]pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine

6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-[6-[(3R)-1-propan-2-ylpyrrolidin-3-yl]oxy-3-pyridinyl]pyrimidin-4-amine;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]oxypiperidin-1-yl]-phenylmethanone;5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyrimidin-2-amine;5-[2-morpholin-4-yl-6-(5-piperidin-4-yloxy-3-pyridinyl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine;5-[2-morpholin-4-yl-6-[5-(1-propan-2-ylpiperidin-4-yl)oxy-3-pyridinyl]pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine (PubChem CID 158779723) has the molecular formula C120H136F15N35O11 and a molecular weight of 2529.61 g/mol. Its IUPAC name is 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-[6-[(3R)-1-propan-2-ylpyrrolidin-3-yl]oxy-3-pyridinyl]pyrimidin-4-amine;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]oxypiperidin-1-yl]-phenylmethanone;5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyrimidin-2-amine;5-[2-morpholin-4-yl-6-(5-piperidin-4-yloxy-3-pyridinyl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine;5-[2-morpholin-4-yl-6-[5-(1-propan-2-ylpiperidin-4-yl)oxy-3-pyridinyl]pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine.

Molecular Properties

Compound Name6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-[6-[(3R)-1-propan-2-ylpyrrolidin-3-yl]oxy-3-pyridinyl]pyrimidin-4-amine;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]oxypiperidin-1-yl]-phenylmethanone;5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyrimidin-2-amine;5-[2-morpholin-4-yl-6-(5-piperidin-4-yloxy-3-pyridinyl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine;5-[2-morpholin-4-yl-6-[5-(1-propan-2-ylpiperidin-4-yl)oxy-3-pyridinyl]pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine
PubChem CID158779723
Molecular FormulaC120H136F15N35O11
Molecular Weight2529.61 g/mol
Exact Mass2528.09
IUPAC Name6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-[6-[(3R)-1-propan-2-ylpyrrolidin-3-yl]oxy-3-pyridinyl]pyrimidin-4-amine;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]oxypiperidin-1-yl]-phenylmethanone;5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyrimidin-2-amine;5-[2-morpholin-4-yl-6-(5-piperidin-4-yloxy-3-pyridinyl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine;5-[2-morpholin-4-yl-6-[5-(1-propan-2-ylpiperidin-4-yl)oxy-3-pyridinyl]pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine
SMILESCC(C)N1CCC(Oc2cncc(-c3cc(-c4cnc(N)cc4C(F)(F)F)nc(N4CCOCC4)n3)c2)CC1.CC(C)N1CC[C@@H](Oc2ccc(Nc3cc(-c4cnc(N)cc4C(F)(F)F)nc(N4CCOCC4)n3)cn2)C1.Nc1cc(C(F)(F)F)c(-c2cc(-c3cncc(OC4CCNCC4)c3)nc(N3CCOCC3)n2)cn1.Nc1cc(C(F)(F)F)c(-c2cc(OC3CCN(C(=O)c4ccccc4)CC3)nc(N3CCOCC3)n2)cn1.Nc1ncc(-c2cc(N3CCOCC3)nc(N3CCOCC3)n2)c(C(F)(F)F)n1
InChIInChI=1S/C27H32F3N7O2.C26H31F3N8O2.C26H27F3N6O3.C24H26F3N7O2.C17H20F3N7O2/c1-17(2)36-5-3-19(4-6-36)39-20-11-18(14-32-15-20)23-13-24(35-26(34-23)37-7-9-38-10-8-37)21-16-33-25(31)12-22(21)27(28,29)30;1-16(2)37-6-5-18(15-37)39-24-4-3-17(13-32-24)33-23-12-21(34-25(35-23)36-7-9-38-10-8-36)19-14-31-22(30)11-20(19)26(27,28)29;27-26(28,29)20-14-22(30)31-16-19(20)21-15-23(33-25(32-21)35-10-12-37-13-11-35)38-18-6-8-34(9-7-18)24(36)17-4-2-1-3-5-17;25-24(26,27)19-10-22(28)31-14-18(19)21-11-20(32-23(33-21)34-5-7-35-8-6-34)15-9-17(13-30-12-15)36-16-1-3-29-4-2-16;18-17(19,20)14-11(10-22-15(21)25-14)12-9-13(26-1-5-28-6-2-26)24-16(23-12)27-3-7-29-8-4-27/h11-17,19H,3-10H2,1-2H3,(H2,31,33);3-4,11-14,16,18H,5-10,15H2,1-2H3,(H2,30,31)(H,33,34,35);1-5,14-16,18H,6-13H2,(H2,30,31);9-14,16,29H,1-8H2,(H2,28,31);9-10H,1-8H2,(H2,21,22,25)/t;18-;;;/m.1.../s1
InChIKeyIQXOFRUGSNBZHI-OEGAAENXSA-N
XLogP16.30
TPSA537.60 Ų
H-Bond Donors7
H-Bond Acceptors45
Rotatable Bonds26
Heavy Atoms181
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002529.61
LogP ≤ 516.30
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1045

Analyze 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-[6-[(3R)-1-propan-2-ylpyrrolidin-3-yl]oxy-3-pyridinyl]pyrimidin-4-amine;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]oxypiperidin-1-yl]-phenylmethanone;5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyrimidin-2-amine;5-[2-morpholin-4-yl-6-(5-piperidin-4-yloxy-3-pyridinyl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine;5-[2-morpholin-4-yl-6-[5-(1-propan-2-ylpiperidin-4-yl)oxy-3-pyridinyl]pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine with MolForge

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Related Compounds

N-(2,6-difluorophenyl)-3-(3-(2-(4-(4-((2R,6S)-2,6-dimethylmorpholino)piperidin-1-yl)-2-methoxyphenylamino)pyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)benzamide
CID 44571818
5-(4-(((1S,2S)-2-(5-methoxypyridin-2-yl)cyclopropyl)methoxy)-2-methylpyrimidin-5-yl)-N-(2,2,2-trifluoroethyl)picolinamide
CID 76282779
US10040805, Example 3
CID 121455013
US10040805, Example 14
CID 121461265
N-ethyl-5-[2-methyl-8-[[4-[4-(trifluoromethyl)phenyl]phenyl]methoxy]imidazo[1,2-a]pyridin-3-yl]pyridine-2-carboxamide;hydrochloride
CID 156013916
Propan-2-yl 2-[[6-[2-(dimethylamino)ethyl-methylamino]-5-(prop-2-enoylamino)-2-(2,2,2-trifluoroethoxy)-3-pyridinyl]amino]-4-(1-methylindol-2-yl)pyrimidine-5-carboxylate
CID 168275099
Propan-2-yl 4-(1-cyclopropylindol-2-yl)-2-[[6-[2-(dimethylamino)ethyl-methylamino]-5-(prop-2-enoylamino)-2-(2,2,2-trifluoroethoxy)-3-pyridinyl]amino]pyrimidine-5-carboxylate
CID 168284326
3-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-2-(propyloxy)phenyl]amino}-4-pyrimidinyl)-imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
CID 59452683
3-[3-[2-[4-[4-[4-(2,2-difluoroethyl)piperazin-1-yl]piperidin-1-yl]-2-ethoxyanilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
CID 59452689
N-(2,6-difluorophenyl)-3-[3-[2-[4-(4-piperidin-1-ylpiperidin-1-yl)-2-propan-2-yloxyanilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide
CID 59452702
N-(2,6-difluorophenyl)-3-(3-{2-[(2-(ethyloxy)-4-{4-[1-(2-fluoroethyl)-4-piperidinyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
CID 59452746
N-(2,6-difluorophenyl)-3-[3-[2-[2-ethoxy-4-[4-[4-(3,3,3-trifluoropropyl)piperazin-1-yl]piperidin-1-yl]anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide
CID 59452796

Frequently Asked Questions

What is the IUPAC name of 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-[6-[(3R)-1-propan-2-ylpyrrolidin-3-yl]oxy-3-pyridinyl]pyrimidin-4-amine;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]oxypiperidin-1-yl]-phenylmethanone;5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyrimidin-2-amine;5-[2-morpholin-4-yl-6-(5-piperidin-4-yloxy-3-pyridinyl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine;5-[2-morpholin-4-yl-6-[5-(1-propan-2-ylpiperidin-4-yl)oxy-3-pyridinyl]pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine?
The IUPAC name of 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-[6-[(3R)-1-propan-2-ylpyrrolidin-3-yl]oxy-3-pyridinyl]pyrimidin-4-amine;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]oxypiperidin-1-yl]-phenylmethanone;5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyrimidin-2-amine;5-[2-morpholin-4-yl-6-(5-piperidin-4-yloxy-3-pyridinyl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine;5-[2-morpholin-4-yl-6-[5-(1-propan-2-ylpiperidin-4-yl)oxy-3-pyridinyl]pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine (CID 158779723) is 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-[6-[(3R)-1-propan-2-ylpyrrolidin-3-yl]oxy-3-pyridinyl]pyrimidin-4-amine;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]oxypiperidin-1-yl]-phenylmethanone;5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyrimidin-2-amine;5-[2-morpholin-4-yl-6-(5-piperidin-4-yloxy-3-pyridinyl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine;5-[2-morpholin-4-yl-6-[5-(1-propan-2-ylpiperidin-4-yl)oxy-3-pyridinyl]pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine.
What is the SMILES notation for 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-[6-[(3R)-1-propan-2-ylpyrrolidin-3-yl]oxy-3-pyridinyl]pyrimidin-4-amine;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]oxypiperidin-1-yl]-phenylmethanone;5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyrimidin-2-amine;5-[2-morpholin-4-yl-6-(5-piperidin-4-yloxy-3-pyridinyl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine;5-[2-morpholin-4-yl-6-[5-(1-propan-2-ylpiperidin-4-yl)oxy-3-pyridinyl]pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine?
The canonical SMILES for 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-[6-[(3R)-1-propan-2-ylpyrrolidin-3-yl]oxy-3-pyridinyl]pyrimidin-4-amine;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]oxypiperidin-1-yl]-phenylmethanone;5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyrimidin-2-amine;5-[2-morpholin-4-yl-6-(5-piperidin-4-yloxy-3-pyridinyl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine;5-[2-morpholin-4-yl-6-[5-(1-propan-2-ylpiperidin-4-yl)oxy-3-pyridinyl]pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine is CC(C)N1CCC(Oc2cncc(-c3cc(-c4cnc(N)cc4C(F)(F)F)nc(N4CCOCC4)n3)c2)CC1.CC(C)N1CC[C@@H](Oc2ccc(Nc3cc(-c4cnc(N)cc4C(F)(F)F)nc(N4CCOCC4)n3)cn2)C1.Nc1cc(C(F)(F)F)c(-c2cc(-c3cncc(OC4CCNCC4)c3)nc(N3CCOCC3)n2)cn1.Nc1cc(C(F)(F)F)c(-c2cc(OC3CCN(C(=O)c4ccccc4)CC3)nc(N3CCOCC3)n2)cn1.Nc1ncc(-c2cc(N3CCOCC3)nc(N3CCOCC3)n2)c(C(F)(F)F)n1.
What is the InChIKey of 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-[6-[(3R)-1-propan-2-ylpyrrolidin-3-yl]oxy-3-pyridinyl]pyrimidin-4-amine;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]oxypiperidin-1-yl]-phenylmethanone;5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyrimidin-2-amine;5-[2-morpholin-4-yl-6-(5-piperidin-4-yloxy-3-pyridinyl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine;5-[2-morpholin-4-yl-6-[5-(1-propan-2-ylpiperidin-4-yl)oxy-3-pyridinyl]pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine?
The InChIKey is IQXOFRUGSNBZHI-OEGAAENXSA-N. The full InChI is InChI=1S/C27H32F3N7O2.C26H31F3N8O2.C26H27F3N6O3.C24H26F3N7O2.C17H20F3N7O2/c1-17(2)36-5-3-19(4-6-36)39-20-11-18(14-32-15-20)23-13-24(35-26(34-23)37-7-9-38-10-8-37)21-16-33-25(31)12-22(21)27(28,29)30;1-16(2)37-6-5-18(15-37)39-24-4-3-17(13-32-24)33-23-12-21(34-25(35-23)36-7-9-38-10-8-36)19-14-31-22(30)11-20(19)26(27,28)29;27-26(28,29)20-14-22(30)31-16-19(20)21-15-23(33-25(32-21)35-10-12-37-13-11-35)38-18-6-8-34(9-7-18)24(36)17-4-2-1-3-5-17;25-24(26,27)19-10-22(28)31-14-18(19)21-11-20(32-23(33-21)34-5-7-35-8-6-34)15-9-17(13-30-12-15)36-16-1-3-29-4-2-16;18-17(19,20)14-11(10-22-15(21)25-14)12-9-13(26-1-5-28-6-2-26)24-16(23-12)27-3-7-29-8-4-27/h11-17,19H,3-10H2,1-2H3,(H2,31,33);3-4,11-14,16,18H,5-10,15H2,1-2H3,(H2,30,31)(H,33,34,35);1-5,14-16,18H,6-13H2,(H2,30,31);9-14,16,29H,1-8H2,(H2,28,31);9-10H,1-8H2,(H2,21,22,25)/t;18-;;;/m.1.../s1.
What are the key properties of 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-[6-[(3R)-1-propan-2-ylpyrrolidin-3-yl]oxy-3-pyridinyl]pyrimidin-4-amine;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]oxypiperidin-1-yl]-phenylmethanone;5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyrimidin-2-amine;5-[2-morpholin-4-yl-6-(5-piperidin-4-yloxy-3-pyridinyl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine;5-[2-morpholin-4-yl-6-[5-(1-propan-2-ylpiperidin-4-yl)oxy-3-pyridinyl]pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine?
6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-[6-[(3R)-1-propan-2-ylpyrrolidin-3-yl]oxy-3-pyridinyl]pyrimidin-4-amine;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]oxypiperidin-1-yl]-phenylmethanone;5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyrimidin-2-amine;5-[2-morpholin-4-yl-6-(5-piperidin-4-yloxy-3-pyridinyl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine;5-[2-morpholin-4-yl-6-[5-(1-propan-2-ylpiperidin-4-yl)oxy-3-pyridinyl]pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine has a molecular weight of 2529.61 g/mol, XLogP of 16.30, 26 rotatable bonds, 7 hydrogen bond donors, and 45 hydrogen bond acceptors.
Where does this data come from?
All data for 6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-[6-[(3R)-1-propan-2-ylpyrrolidin-3-yl]oxy-3-pyridinyl]pyrimidin-4-amine;[4-[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]oxypiperidin-1-yl]-phenylmethanone;5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyrimidin-2-amine;5-[2-morpholin-4-yl-6-(5-piperidin-4-yloxy-3-pyridinyl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine;5-[2-morpholin-4-yl-6-[5-(1-propan-2-ylpiperidin-4-yl)oxy-3-pyridinyl]pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine is sourced from PubChem (CID 158779723), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).