2-(5-chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine

C101H75Cl3F7N23 — CID 158785902

IUPAC2-(5-chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine
SMILESCn1cc(-c2cncc(-c3cc(-c4cc(C(F)(F)F)ccc4F)nc4ncccc34)c2)cn1.Cn1cc(-c2cncc(-c3cc(-c4cc(Cl)ccc4F)nc4ncccc34)c2)cn1.Fc1ccc(Cl)cc1-c1cc(-c2cncc(-c3cnn(C4CCNCC4)c3)c2)c2cccnc2n1.Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1-c1cc(-c2cc(Cl)ccc2F)nc2ncccc12
InChIInChI=1S/C27H23ClFN7.C27H22ClFN6.C24H15F4N5.C23H15ClFN5/c28-18-3-4-24(29)23(11-18)25-12-21(20-2-1-7-32-27(20)35-25)22-10-16(13-33-26(22)30)17-14-34-36(15-17)19-5-8-31-9-6-19;28-20-3-4-25(29)24(11-20)26-12-23(22-2-1-7-32-27(22)34-26)18-10-17(13-31-14-18)19-15-33-35(16-19)21-5-8-30-9-6-21;1-33-13-16(12-31-33)14-7-15(11-29-10-14)19-9-22(32-23-18(19)3-2-6-30-23)20-8-17(24(26,27)28)4-5-21(20)25;1-30-13-16(12-28-30)14-7-15(11-26-10-14)19-9-22(20-8-17(24)4-5-21(20)25)29-23-18(19)3-2-6-27-23/h1-4,7,10-15,19,31H,5-6,8-9H2,(H2,30,33);1-4,7,10-16,21,30H,5-6,8-9H2;2-13H,1H3;2-13H,1H3
InChIKeyIRRIBHHYLKQFTH-UHFFFAOYSA-N
MW1850.22 g/mol
LogP22.93
Rot. Bonds14

About 2-(5-chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine

2-(5-chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine (PubChem CID 158785902) has the molecular formula C101H75Cl3F7N23 and a molecular weight of 1850.22 g/mol. Its IUPAC name is 2-(5-chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine.

Molecular Properties

Compound Name2-(5-chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine
PubChem CID158785902
Molecular FormulaC101H75Cl3F7N23
Molecular Weight1850.22 g/mol
Exact Mass1847.55
IUPAC Name2-(5-chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine
SMILESCn1cc(-c2cncc(-c3cc(-c4cc(C(F)(F)F)ccc4F)nc4ncccc34)c2)cn1.Cn1cc(-c2cncc(-c3cc(-c4cc(Cl)ccc4F)nc4ncccc34)c2)cn1.Fc1ccc(Cl)cc1-c1cc(-c2cncc(-c3cnn(C4CCNCC4)c3)c2)c2cccnc2n1.Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1-c1cc(-c2cc(Cl)ccc2F)nc2ncccc12
InChIInChI=1S/C27H23ClFN7.C27H22ClFN6.C24H15F4N5.C23H15ClFN5/c28-18-3-4-24(29)23(11-18)25-12-21(20-2-1-7-32-27(20)35-25)22-10-16(13-33-26(22)30)17-14-34-36(15-17)19-5-8-31-9-6-19;28-20-3-4-25(29)24(11-20)26-12-23(22-2-1-7-32-27(22)34-26)18-10-17(13-31-14-18)19-15-33-35(16-19)21-5-8-30-9-6-21;1-33-13-16(12-31-33)14-7-15(11-29-10-14)19-9-22(32-23-18(19)3-2-6-30-23)20-8-17(24(26,27)28)4-5-21(20)25;1-30-13-16(12-28-30)14-7-15(11-26-10-14)19-9-22(20-8-17(24)4-5-21(20)25)29-23-18(19)3-2-6-27-23/h1-4,7,10-15,19,31H,5-6,8-9H2,(H2,30,33);1-4,7,10-16,21,30H,5-6,8-9H2;2-13H,1H3;2-13H,1H3
InChIKeyIRRIBHHYLKQFTH-UHFFFAOYSA-N
XLogP22.93
TPSA276.04 Ų
H-Bond Donors3
H-Bond Acceptors23
Rotatable Bonds14
Heavy Atoms134
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001850.22
LogP ≤ 522.93
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 1023

Analyze 2-(5-chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine with MolForge

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Related Compounds

2-(5-Chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine
CID 53328062
2-[2-Fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-3-yl]-1,8-naphthyridine
CID 53344845
3-[2-(5-Chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine
CID 53344957
2-(5-Chloro-2-fluorophenyl)-4-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine
CID 53345068
2-(5-Chloro-2-fluorophenyl)-4-[5-[1-(1-ethylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine
CID 53345406
2-(5-Chloro-2-fluorophenyl)-4-[5-[1-(1-methylpyrrolidin-3-yl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine
CID 53345626
2-(5-chloro-2-fluorophenyl)-4-[5-[1-[(3S)-1-methylpyrrolidin-3-yl]pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine
CID 53345723
2-(5-chloro-2-fluorophenyl)-4-[5-[1-[(3R)-1-methylpyrrolidin-3-yl]pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine
CID 53345724
5-[2-(5-chloro-2-fluoro-phenyl)-[1,8]naphthyridin-4-yl]-3-(1-methyl-1H-pyrazol-4-yl)-pyridin-2-ylamine
CID 67363122
2-(5-Chloro-2-fluorophenyl)-4-[5-[1-(2-piperazin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine
CID 68264549
5-[2-(5-Chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-3-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]pyridin-2-amine
CID 68264729
2-[2-Fluoro-5-(2-fluoropropan-2-yl)phenyl]-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine
CID 68264943

Frequently Asked Questions

What is the IUPAC name of 2-(5-chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine?
The IUPAC name of 2-(5-chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine (CID 158785902) is 2-(5-chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine.
What is the SMILES notation for 2-(5-chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine?
The canonical SMILES for 2-(5-chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine is Cn1cc(-c2cncc(-c3cc(-c4cc(C(F)(F)F)ccc4F)nc4ncccc34)c2)cn1.Cn1cc(-c2cncc(-c3cc(-c4cc(Cl)ccc4F)nc4ncccc34)c2)cn1.Fc1ccc(Cl)cc1-c1cc(-c2cncc(-c3cnn(C4CCNCC4)c3)c2)c2cccnc2n1.Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1-c1cc(-c2cc(Cl)ccc2F)nc2ncccc12.
What is the InChIKey of 2-(5-chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine?
The InChIKey is IRRIBHHYLKQFTH-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H23ClFN7.C27H22ClFN6.C24H15F4N5.C23H15ClFN5/c28-18-3-4-24(29)23(11-18)25-12-21(20-2-1-7-32-27(20)35-25)22-10-16(13-33-26(22)30)17-14-34-36(15-17)19-5-8-31-9-6-19;28-20-3-4-25(29)24(11-20)26-12-23(22-2-1-7-32-27(22)34-26)18-10-17(13-31-14-18)19-15-33-35(16-19)21-5-8-30-9-6-21;1-33-13-16(12-31-33)14-7-15(11-29-10-14)19-9-22(32-23-18(19)3-2-6-30-23)20-8-17(24(26,27)28)4-5-21(20)25;1-30-13-16(12-28-30)14-7-15(11-26-10-14)19-9-22(20-8-17(24)4-5-21(20)25)29-23-18(19)3-2-6-27-23/h1-4,7,10-15,19,31H,5-6,8-9H2,(H2,30,33);1-4,7,10-16,21,30H,5-6,8-9H2;2-13H,1H3;2-13H,1H3.
What are the key properties of 2-(5-chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine?
2-(5-chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine has a molecular weight of 1850.22 g/mol, XLogP of 22.93, 14 rotatable bonds, 3 hydrogen bond donors, and 23 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(5-chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine is sourced from PubChem (CID 158785902), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).