N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-fluoro-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-methoxy-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)-2-pyridinyl]methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]azetidine-1-carboxamide

C84H80F11N23O5 — CID 158788791

IUPACN-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-fluoro-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-methoxy-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)-2-pyridinyl]methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]azetidine-1-carboxamide
SMILESCOC1(Cc2nccn2C)CN(C(=O)Nc2nc(-c3ccc(F)cc3)ccc2N)C1.Cn1ccnc1CC1(F)CN(C(=O)Nc2nc(-c3ccc(F)cc3)ccc2N)C1.Nc1ccc(-c2ccc(F)cc2)nc1NC(=O)N1CC(Cc2ccc(C(F)(F)F)cn2)C1.Nc1ccc(-c2ccc(F)cc2)nc1NC(=O)N1CC(Cc2ncc(C(F)(F)F)cn2)C1
InChIInChI=1S/C22H19F4N5O.C21H18F4N6O.C21H23FN6O2.C20H20F2N6O/c23-16-4-1-14(2-5-16)19-8-7-18(27)20(29-19)30-21(32)31-11-13(12-31)9-17-6-3-15(10-28-17)22(24,25)26;22-15-3-1-13(2-4-15)17-6-5-16(26)19(29-17)30-20(32)31-10-12(11-31)7-18-27-8-14(9-28-18)21(23,24)25;1-27-10-9-24-18(27)11-21(30-2)12-28(13-21)20(29)26-19-16(23)7-8-17(25-19)14-3-5-15(22)6-4-14;1-27-9-8-24-17(27)10-20(22)11-28(12-20)19(29)26-18-15(23)6-7-16(25-18)13-2-4-14(21)5-3-13/h1-8,10,13H,9,11-12,27H2,(H,29,30,32);1-6,8-9,12H,7,10-11,26H2,(H,29,30,32);3-10H,11-13,23H2,1-2H3,(H,25,26,29);2-9H,10-12,23H2,1H3,(H,25,26,29)
InChIKeyIRZZYLRHMWPWTB-UHFFFAOYSA-N
MW1700.70 g/mol
LogP14.26
Rot. Bonds17

About N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-fluoro-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-methoxy-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)-2-pyridinyl]methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]azetidine-1-carboxamide

N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-fluoro-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-methoxy-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)-2-pyridinyl]methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]azetidine-1-carboxamide (PubChem CID 158788791) has the molecular formula C84H80F11N23O5 and a molecular weight of 1700.70 g/mol. Its IUPAC name is N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-fluoro-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-methoxy-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)-2-pyridinyl]methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]azetidine-1-carboxamide.

Molecular Properties

Compound NameN-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-fluoro-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-methoxy-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)-2-pyridinyl]methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]azetidine-1-carboxamide
PubChem CID158788791
Molecular FormulaC84H80F11N23O5
Molecular Weight1700.70 g/mol
Exact Mass1699.65
IUPAC NameN-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-fluoro-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-methoxy-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)-2-pyridinyl]methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]azetidine-1-carboxamide
SMILESCOC1(Cc2nccn2C)CN(C(=O)Nc2nc(-c3ccc(F)cc3)ccc2N)C1.Cn1ccnc1CC1(F)CN(C(=O)Nc2nc(-c3ccc(F)cc3)ccc2N)C1.Nc1ccc(-c2ccc(F)cc2)nc1NC(=O)N1CC(Cc2ccc(C(F)(F)F)cn2)C1.Nc1ccc(-c2ccc(F)cc2)nc1NC(=O)N1CC(Cc2ncc(C(F)(F)F)cn2)C1
InChIInChI=1S/C22H19F4N5O.C21H18F4N6O.C21H23FN6O2.C20H20F2N6O/c23-16-4-1-14(2-5-16)19-8-7-18(27)20(29-19)30-21(32)31-11-13(12-31)9-17-6-3-15(10-28-17)22(24,25)26;22-15-3-1-13(2-4-15)17-6-5-16(26)19(29-17)30-20(32)31-10-12(11-31)7-18-27-8-14(9-28-18)21(23,24)25;1-27-10-9-24-18(27)11-21(30-2)12-28(13-21)20(29)26-19-16(23)7-8-17(25-19)14-3-5-15(22)6-4-14;1-27-9-8-24-17(27)10-20(22)11-28(12-20)19(29)26-18-15(23)6-7-16(25-18)13-2-4-14(21)5-3-13/h1-8,10,13H,9,11-12,27H2,(H,29,30,32);1-6,8-9,12H,7,10-11,26H2,(H,29,30,32);3-10H,11-13,23H2,1-2H3,(H,25,26,29);2-9H,10-12,23H2,1H3,(H,25,26,29)
InChIKeyIRZZYLRHMWPWTB-UHFFFAOYSA-N
XLogP14.26
TPSA368.54 Ų
H-Bond Donors8
H-Bond Acceptors20
Rotatable Bonds17
Heavy Atoms123
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001700.70
LogP ≤ 514.26
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1020

Analyze N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-fluoro-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-methoxy-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)-2-pyridinyl]methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]azetidine-1-carboxamide with MolForge

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Launch Full Analysis

Related Compounds

N-[3-amino-6-(4-fluoro-2-methylphenyl)-2-pyridinyl]-3-[(5-methylpyrimidin-2-yl)methyl]azetidine-1-carboxamide
CID 159511705
N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-azabicyclo[3.1.0]hexane-3-carboxamide;methanol
CID 145230400
N-[3-amino-6-(2,4-difluorophenyl)-2-pyridinyl]-3-(pyrazin-2-ylmethyl)azetidine-1-carboxamide
CID 147018729
N-[3-amino-6-(4-fluoro-2-methylphenyl)-2-pyridinyl]-3-[(4,6-dimethylpyrimidin-2-yl)methyl]azetidine-1-carboxamide
CID 157484665
(3R)-N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-pyrimidin-2-ylpyrrolidine-1-carboxamide
CID 153394093
N-[3-amino-6-(4-fluoro-2-methylphenyl)-2-pyridinyl]-3-(imidazo[1,5-a]pyridin-7-ylmethyl)azetidine-1-carboxamide
CID 159511707
N-[3-amino-6-(2,4-difluorophenyl)-2-pyridinyl]-3-(pyrazol-1-ylmethyl)azetidine-1-carboxamide
CID 149278130
N-[(1-methylimidazol-2-yl)methyl]-5-(trifluoromethyl)pyridin-2-amine
CID 63295527
N-(2-methoxyphenyl)-3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]azetidine-1-carboxamide
CID 122247691
5-amino-6-[(1-methylimidazol-2-yl)methylamino]pyridine-2-carboxamide
CID 114406596
[6-[3-(1-fluorocyclopropyl)-1H-1,2,4-triazol-5-yl]-2-azaspiro[3.3]heptan-2-yl]-[6-[[5-(trifluoromethyl)-2-pyridinyl]methyl]-2-azaspiro[3.3]heptan-2-yl]methanone
CID 169104804
2-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-1-[3-[difluoro(pyridin-2-yl)methyl]azetidin-1-yl]ethanone
CID 162163426

Frequently Asked Questions

What is the IUPAC name of N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-fluoro-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-methoxy-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)-2-pyridinyl]methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]azetidine-1-carboxamide?
The IUPAC name of N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-fluoro-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-methoxy-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)-2-pyridinyl]methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]azetidine-1-carboxamide (CID 158788791) is N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-fluoro-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-methoxy-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)-2-pyridinyl]methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]azetidine-1-carboxamide.
What is the SMILES notation for N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-fluoro-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-methoxy-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)-2-pyridinyl]methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]azetidine-1-carboxamide?
The canonical SMILES for N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-fluoro-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-methoxy-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)-2-pyridinyl]methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]azetidine-1-carboxamide is COC1(Cc2nccn2C)CN(C(=O)Nc2nc(-c3ccc(F)cc3)ccc2N)C1.Cn1ccnc1CC1(F)CN(C(=O)Nc2nc(-c3ccc(F)cc3)ccc2N)C1.Nc1ccc(-c2ccc(F)cc2)nc1NC(=O)N1CC(Cc2ccc(C(F)(F)F)cn2)C1.Nc1ccc(-c2ccc(F)cc2)nc1NC(=O)N1CC(Cc2ncc(C(F)(F)F)cn2)C1.
What is the InChIKey of N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-fluoro-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-methoxy-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)-2-pyridinyl]methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]azetidine-1-carboxamide?
The InChIKey is IRZZYLRHMWPWTB-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H19F4N5O.C21H18F4N6O.C21H23FN6O2.C20H20F2N6O/c23-16-4-1-14(2-5-16)19-8-7-18(27)20(29-19)30-21(32)31-11-13(12-31)9-17-6-3-15(10-28-17)22(24,25)26;22-15-3-1-13(2-4-15)17-6-5-16(26)19(29-17)30-20(32)31-10-12(11-31)7-18-27-8-14(9-28-18)21(23,24)25;1-27-10-9-24-18(27)11-21(30-2)12-28(13-21)20(29)26-19-16(23)7-8-17(25-19)14-3-5-15(22)6-4-14;1-27-9-8-24-17(27)10-20(22)11-28(12-20)19(29)26-18-15(23)6-7-16(25-18)13-2-4-14(21)5-3-13/h1-8,10,13H,9,11-12,27H2,(H,29,30,32);1-6,8-9,12H,7,10-11,26H2,(H,29,30,32);3-10H,11-13,23H2,1-2H3,(H,25,26,29);2-9H,10-12,23H2,1H3,(H,25,26,29).
What are the key properties of N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-fluoro-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-methoxy-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)-2-pyridinyl]methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]azetidine-1-carboxamide?
N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-fluoro-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-methoxy-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)-2-pyridinyl]methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]azetidine-1-carboxamide has a molecular weight of 1700.70 g/mol, XLogP of 14.26, 17 rotatable bonds, 8 hydrogen bond donors, and 20 hydrogen bond acceptors.
Where does this data come from?
All data for N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-fluoro-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-methoxy-3-[(1-methylimidazol-2-yl)methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)-2-pyridinyl]methyl]azetidine-1-carboxamide;N-[3-amino-6-(4-fluorophenyl)-2-pyridinyl]-3-[[5-(trifluoromethyl)pyrimidin-2-yl]methyl]azetidine-1-carboxamide is sourced from PubChem (CID 158788791), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).