1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonyl-2-methylpyrrolidin-2-yl]-3-[5-methoxy-4-[6-(trifluoromethyl)-3-pyridinyl]-2-pyridinyl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[2-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[3-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;3-[3-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-oxopropyl]-5-[6-(trifluoromethyl)-3-pyridinyl]benzonitrile;1-[(2R,3S)-3-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[4-(trifluoromethoxy)phenyl]pyrimidin-4-yl]propan-1-one;(3R,5S)-1-(4-fluorophenyl)sulfonyl-5-[3-[3-methoxy-1-[4-(trifluoromethyl)phenyl]pyrazol-4-yl]propanoyl]pyrrolidine-3-carbonitrile

C149H124F31N19O21S6 — CID 158804265

About 1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonyl-2-methylpyrrolidin-2-yl]-3-[5-methoxy-4-[6-(trifluoromethyl)-3-pyridinyl]-2-pyridinyl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[2-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[3-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;3-[3-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-oxopropyl]-5-[6-(trifluoromethyl)-3-pyridinyl]benzonitrile;1-[(2R,3S)-3-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[4-(trifluoromethoxy)phenyl]pyrimidin-4-yl]propan-1-one;(3R,5S)-1-(4-fluorophenyl)sulfonyl-5-[3-[3-methoxy-1-[4-(trifluoromethyl)phenyl]pyrazol-4-yl]propanoyl]pyrrolidine-3-carbonitrile

1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonyl-2-methylpyrrolidin-2-yl]-3-[5-methoxy-4-[6-(trifluoromethyl)-3-pyridinyl]-2-pyridinyl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[2-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[3-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;3-[3-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-oxopropyl]-5-[6-(trifluoromethyl)-3-pyridinyl]benzonitrile;1-[(2R,3S)-3-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[4-(trifluoromethoxy)phenyl]pyrimidin-4-yl]propan-1-one;(3R,5S)-1-(4-fluorophenyl)sulfonyl-5-[3-[3-methoxy-1-[4-(trifluoromethyl)phenyl]pyrazol-4-yl]propanoyl]pyrrolidine-3-carbonitrile (PubChem CID 158804265) has the molecular formula C149H124F31N19O21S6 and a molecular weight of 3298.08 g/mol. Its IUPAC name is 1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonyl-2-methylpyrrolidin-2-yl]-3-[5-methoxy-4-[6-(trifluoromethyl)-3-pyridinyl]-2-pyridinyl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[2-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[3-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;3-[3-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-oxopropyl]-5-[6-(trifluoromethyl)-3-pyridinyl]benzonitrile;1-[(2R,3S)-3-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[4-(trifluoromethoxy)phenyl]pyrimidin-4-yl]propan-1-one;(3R,5S)-1-(4-fluorophenyl)sulfonyl-5-[3-[3-methoxy-1-[4-(trifluoromethyl)phenyl]pyrazol-4-yl]propanoyl]pyrrolidine-3-carbonitrile.

Molecular Properties

• Compound Name: 1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonyl-2-methylpyrrolidin-2-yl]-3-[5-methoxy-4-[6-(trifluoromethyl)-3-pyridinyl]-2-pyridinyl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[2-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[3-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;3-[3-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-oxopropyl]-5-[6-(trifluoromethyl)-3-pyridinyl]benzonitrile;1-[(2R,3S)-3-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[4-(trifluoromethoxy)phenyl]pyrimidin-4-yl]propan-1-one;(3R,5S)-1-(4-fluorophenyl)sulfonyl-5-[3-[3-methoxy-1-[4-(trifluoromethyl)phenyl]pyrazol-4-yl]propanoyl]pyrrolidine-3-carbonitrile
• PubChem CID: 158804265
• Molecular Formula: C149H124F31N19O21S6
• Molecular Weight: 3298.08 g/mol
• Exact Mass: 3295.70
• IUPAC Name: 1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonyl-2-methylpyrrolidin-2-yl]-3-[5-methoxy-4-[6-(trifluoromethyl)-3-pyridinyl]-2-pyridinyl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[2-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[3-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;3-[3-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-oxopropyl]-5-[6-(trifluoromethyl)-3-pyridinyl]benzonitrile;1-[(2R,3S)-3-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[4-(trifluoromethoxy)phenyl]pyrimidin-4-yl]propan-1-one;(3R,5S)-1-(4-fluorophenyl)sulfonyl-5-[3-[3-methoxy-1-[4-(trifluoromethyl)phenyl]pyrazol-4-yl]propanoyl]pyrrolidine-3-carbonitrile
• SMILES: COc1cnc(CCC(=O)[C@]2(C)C[C@@H](F)CN2S(=O)(=O)c2ccc(F)cc2)cc1-c1ccc(C(F)(F)F)nc1.COc1nn(-c2ccc(C(F)(F)F)cc2)cc1CCC(=O)[C@@H]1C[C@@H](C#N)CN1S(=O)(=O)c1ccc(F)cc1.N#Cc1cc(CCC(=O)[C@@H]2C[C@@H](F)CN2S(=O)(=O)c2ccc(F)cc2)cc(-c2ccc(C(F)(F)F)nc2)c1.O=C(CCc1cc(-c2ccc(C(F)(F)F)c(F)c2)ncn1)[C@@H]1C[C@@H](F)CN1S(=O)(=O)c1ccc(F)cc1.O=C(CCc1cc(-c2ccc(C(F)(F)F)cc2F)ncn1)[C@@H]1C[C@@H](F)CN1S(=O)(=O)c1ccc(F)cc1.O=C(CCc1cc(-c2ccc(OC(F)(F)F)cc2)ncn1)[C@@H]1[C@@H](F)CCN1S(=O)(=O)c1ccc(F)cc1
• InChI: InChI=1S/C26H24F5N3O4S.C26H20F5N3O3S.C25H22F4N4O4S.2C24H19F6N3O3S.C24H20F5N3O4S/c1-25(12-18(28)15-34(25)39(36,37)20-7-4-17(27)5-8-20)24(35)10-6-19-11-21(22(38-2)14-32-19)16-3-9-23(33-13-16)26(29,30)31;27-20-3-5-22(6-4-20)38(36,37)34-15-21(28)12-23(34)24(35)7-1-16-9-17(13-32)11-19(10-16)18-2-8-25(33-14-18)26(29,30)31;1-37-24-17(15-32(31-24)20-7-3-18(4-8-20)25(27,28)29)2-11-23(34)22-12-16(13-30)14-33(22)38(35,36)21-9-5-19(26)6-10-21;25-15-2-5-18(6-3-15)37(35,36)33-12-16(26)10-22(33)23(34)8-4-17-11-21(32-13-31-17)19-7-1-14(9-20(19)27)24(28,29)30;25-15-2-5-18(6-3-15)37(35,36)33-12-16(26)10-22(33)23(34)8-4-17-11-21(32-13-31-17)14-1-7-19(20(27)9-14)24(28,29)30;25-16-3-8-19(9-4-16)37(34,35)32-12-11-20(26)23(32)22(33)10-5-17-13-21(31-14-30-17)15-1-6-18(7-2-15)36-24(27,28)29/h3-5,7-9,11,13-14,18H,6,10,12,15H2,1-2H3;2-6,8-11,14,21,23H,1,7,12,15H2;3-10,15-16,22H,2,11-12,14H2,1H3;2*1-3,5-7,9,11,13,16,22H,4,8,10,12H2;1-4,6-9,13-14,20,23H,5,10-12H2/t18-,25+;21-,23+;16-,22-;2*16-,22+;20-,23-/m110110/s1
• InChIKey: ITWGQQFKUNHFRC-VHSMTHIXSA-N
• XLogP: 28.20
• TPSA: 535.80 Ų
• H-Bond Acceptors: 34
• Rotatable Bonds: 45
• Heavy Atoms: 226
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	3298.08
LogP ≤ 5	28.20
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	34

Frequently Asked Questions

What is the IUPAC name of 1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonyl-2-methylpyrrolidin-2-yl]-3-[5-methoxy-4-[6-(trifluoromethyl)-3-pyridinyl]-2-pyridinyl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[2-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[3-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;3-[3-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-oxopropyl]-5-[6-(trifluoromethyl)-3-pyridinyl]benzonitrile;1-[(2R,3S)-3-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[4-(trifluoromethoxy)phenyl]pyrimidin-4-yl]propan-1-one;(3R,5S)-1-(4-fluorophenyl)sulfonyl-5-[3-[3-methoxy-1-[4-(trifluoromethyl)phenyl]pyrazol-4-yl]propanoyl]pyrrolidine-3-carbonitrile?

The IUPAC name of 1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonyl-2-methylpyrrolidin-2-yl]-3-[5-methoxy-4-[6-(trifluoromethyl)-3-pyridinyl]-2-pyridinyl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[2-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[3-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;3-[3-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-oxopropyl]-5-[6-(trifluoromethyl)-3-pyridinyl]benzonitrile;1-[(2R,3S)-3-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[4-(trifluoromethoxy)phenyl]pyrimidin-4-yl]propan-1-one;(3R,5S)-1-(4-fluorophenyl)sulfonyl-5-[3-[3-methoxy-1-[4-(trifluoromethyl)phenyl]pyrazol-4-yl]propanoyl]pyrrolidine-3-carbonitrile (CID 158804265) is 1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonyl-2-methylpyrrolidin-2-yl]-3-[5-methoxy-4-[6-(trifluoromethyl)-3-pyridinyl]-2-pyridinyl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[2-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[3-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;3-[3-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-oxopropyl]-5-[6-(trifluoromethyl)-3-pyridinyl]benzonitrile;1-[(2R,3S)-3-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[4-(trifluoromethoxy)phenyl]pyrimidin-4-yl]propan-1-one;(3R,5S)-1-(4-fluorophenyl)sulfonyl-5-[3-[3-methoxy-1-[4-(trifluoromethyl)phenyl]pyrazol-4-yl]propanoyl]pyrrolidine-3-carbonitrile.

What is the SMILES notation for 1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonyl-2-methylpyrrolidin-2-yl]-3-[5-methoxy-4-[6-(trifluoromethyl)-3-pyridinyl]-2-pyridinyl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[2-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[3-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;3-[3-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-oxopropyl]-5-[6-(trifluoromethyl)-3-pyridinyl]benzonitrile;1-[(2R,3S)-3-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[4-(trifluoromethoxy)phenyl]pyrimidin-4-yl]propan-1-one;(3R,5S)-1-(4-fluorophenyl)sulfonyl-5-[3-[3-methoxy-1-[4-(trifluoromethyl)phenyl]pyrazol-4-yl]propanoyl]pyrrolidine-3-carbonitrile?

The canonical SMILES for 1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonyl-2-methylpyrrolidin-2-yl]-3-[5-methoxy-4-[6-(trifluoromethyl)-3-pyridinyl]-2-pyridinyl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[2-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[3-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;3-[3-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-oxopropyl]-5-[6-(trifluoromethyl)-3-pyridinyl]benzonitrile;1-[(2R,3S)-3-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[4-(trifluoromethoxy)phenyl]pyrimidin-4-yl]propan-1-one;(3R,5S)-1-(4-fluorophenyl)sulfonyl-5-[3-[3-methoxy-1-[4-(trifluoromethyl)phenyl]pyrazol-4-yl]propanoyl]pyrrolidine-3-carbonitrile is COc1cnc(CCC(=O)[C@]2(C)C[C@@H](F)CN2S(=O)(=O)c2ccc(F)cc2)cc1-c1ccc(C(F)(F)F)nc1.COc1nn(-c2ccc(C(F)(F)F)cc2)cc1CCC(=O)[C@@H]1C[C@@H](C#N)CN1S(=O)(=O)c1ccc(F)cc1.N#Cc1cc(CCC(=O)[C@@H]2C[C@@H](F)CN2S(=O)(=O)c2ccc(F)cc2)cc(-c2ccc(C(F)(F)F)nc2)c1.O=C(CCc1cc(-c2ccc(C(F)(F)F)c(F)c2)ncn1)[C@@H]1C[C@@H](F)CN1S(=O)(=O)c1ccc(F)cc1.O=C(CCc1cc(-c2ccc(C(F)(F)F)cc2F)ncn1)[C@@H]1C[C@@H](F)CN1S(=O)(=O)c1ccc(F)cc1.O=C(CCc1cc(-c2ccc(OC(F)(F)F)cc2)ncn1)[C@@H]1[C@@H](F)CCN1S(=O)(=O)c1ccc(F)cc1.

What is the InChIKey of 1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonyl-2-methylpyrrolidin-2-yl]-3-[5-methoxy-4-[6-(trifluoromethyl)-3-pyridinyl]-2-pyridinyl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[2-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[3-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;3-[3-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-oxopropyl]-5-[6-(trifluoromethyl)-3-pyridinyl]benzonitrile;1-[(2R,3S)-3-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[4-(trifluoromethoxy)phenyl]pyrimidin-4-yl]propan-1-one;(3R,5S)-1-(4-fluorophenyl)sulfonyl-5-[3-[3-methoxy-1-[4-(trifluoromethyl)phenyl]pyrazol-4-yl]propanoyl]pyrrolidine-3-carbonitrile?

The InChIKey is ITWGQQFKUNHFRC-VHSMTHIXSA-N. The full InChI is InChI=1S/C26H24F5N3O4S.C26H20F5N3O3S.C25H22F4N4O4S.2C24H19F6N3O3S.C24H20F5N3O4S/c1-25(12-18(28)15-34(25)39(36,37)20-7-4-17(27)5-8-20)24(35)10-6-19-11-21(22(38-2)14-32-19)16-3-9-23(33-13-16)26(29,30)31;27-20-3-5-22(6-4-20)38(36,37)34-15-21(28)12-23(34)24(35)7-1-16-9-17(13-32)11-19(10-16)18-2-8-25(33-14-18)26(29,30)31;1-37-24-17(15-32(31-24)20-7-3-18(4-8-20)25(27,28)29)2-11-23(34)22-12-16(13-30)14-33(22)38(35,36)21-9-5-19(26)6-10-21;25-15-2-5-18(6-3-15)37(35,36)33-12-16(26)10-22(33)23(34)8-4-17-11-21(32-13-31-17)19-7-1-14(9-20(19)27)24(28,29)30;25-15-2-5-18(6-3-15)37(35,36)33-12-16(26)10-22(33)23(34)8-4-17-11-21(32-13-31-17)14-1-7-19(20(27)9-14)24(28,29)30;25-16-3-8-19(9-4-16)37(34,35)32-12-11-20(26)23(32)22(33)10-5-17-13-21(31-14-30-17)15-1-6-18(7-2-15)36-24(27,28)29/h3-5,7-9,11,13-14,18H,6,10,12,15H2,1-2H3;2-6,8-11,14,21,23H,1,7,12,15H2;3-10,15-16,22H,2,11-12,14H2,1H3;2*1-3,5-7,9,11,13,16,22H,4,8,10,12H2;1-4,6-9,13-14,20,23H,5,10-12H2/t18-,25+;21-,23+;16-,22-;2*16-,22+;20-,23-/m110110/s1.

What are the key properties of 1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonyl-2-methylpyrrolidin-2-yl]-3-[5-methoxy-4-[6-(trifluoromethyl)-3-pyridinyl]-2-pyridinyl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[2-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[3-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;3-[3-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-oxopropyl]-5-[6-(trifluoromethyl)-3-pyridinyl]benzonitrile;1-[(2R,3S)-3-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[4-(trifluoromethoxy)phenyl]pyrimidin-4-yl]propan-1-one;(3R,5S)-1-(4-fluorophenyl)sulfonyl-5-[3-[3-methoxy-1-[4-(trifluoromethyl)phenyl]pyrazol-4-yl]propanoyl]pyrrolidine-3-carbonitrile?

1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonyl-2-methylpyrrolidin-2-yl]-3-[5-methoxy-4-[6-(trifluoromethyl)-3-pyridinyl]-2-pyridinyl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[2-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[3-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;3-[3-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-oxopropyl]-5-[6-(trifluoromethyl)-3-pyridinyl]benzonitrile;1-[(2R,3S)-3-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[4-(trifluoromethoxy)phenyl]pyrimidin-4-yl]propan-1-one;(3R,5S)-1-(4-fluorophenyl)sulfonyl-5-[3-[3-methoxy-1-[4-(trifluoromethyl)phenyl]pyrazol-4-yl]propanoyl]pyrrolidine-3-carbonitrile has a molecular weight of 3298.08 g/mol, XLogP of 28.20, 45 rotatable bonds, 0 hydrogen bond donors, and 34 hydrogen bond acceptors.

Where does this data come from?

All data for 1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonyl-2-methylpyrrolidin-2-yl]-3-[5-methoxy-4-[6-(trifluoromethyl)-3-pyridinyl]-2-pyridinyl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[2-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;1-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[3-fluoro-4-(trifluoromethyl)phenyl]pyrimidin-4-yl]propan-1-one;3-[3-[(2S,4R)-4-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-oxopropyl]-5-[6-(trifluoromethyl)-3-pyridinyl]benzonitrile;1-[(2R,3S)-3-fluoro-1-(4-fluorophenyl)sulfonylpyrrolidin-2-yl]-3-[6-[4-(trifluoromethoxy)phenyl]pyrimidin-4-yl]propan-1-one;(3R,5S)-1-(4-fluorophenyl)sulfonyl-5-[3-[3-methoxy-1-[4-(trifluoromethyl)phenyl]pyrazol-4-yl]propanoyl]pyrrolidine-3-carbonitrile is sourced from PubChem (CID 158804265), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).