trilithium;2-(1,3-benzothiazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzothiazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzothiazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;2-(1,3-benzoxazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzoxazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzoxazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;heptyl-[5-phenoxazin-10-yl-2-(1-phenylbenzimidazol-2-yl)phenyl]azanide;2-(1-methylbenzimidazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;5-(10-methylphenazin-5-yl)-2-(1-phenylbenzimidazol-3-ium-2-yl)phenolate;zinc

C250H223Li3N30O12S3Zn3 — CID 158824889

About trilithium;2-(1,3-benzothiazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzothiazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzothiazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;2-(1,3-benzoxazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzoxazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzoxazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;heptyl-[5-phenoxazin-10-yl-2-(1-phenylbenzimidazol-2-yl)phenyl]azanide;2-(1-methylbenzimidazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;5-(10-methylphenazin-5-yl)-2-(1-phenylbenzimidazol-3-ium-2-yl)phenolate;zinc

trilithium;2-(1,3-benzothiazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzothiazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzothiazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;2-(1,3-benzoxazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzoxazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzoxazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;heptyl-[5-phenoxazin-10-yl-2-(1-phenylbenzimidazol-2-yl)phenyl]azanide;2-(1-methylbenzimidazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;5-(10-methylphenazin-5-yl)-2-(1-phenylbenzimidazol-3-ium-2-yl)phenolate;zinc (PubChem CID 158824889) has the molecular formula C250H223Li3N30O12S3Zn3 and a molecular weight of 4152.93 g/mol. Its IUPAC name is trilithium;2-(1,3-benzothiazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzothiazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzothiazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;2-(1,3-benzoxazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzoxazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzoxazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;heptyl-[5-phenoxazin-10-yl-2-(1-phenylbenzimidazol-2-yl)phenyl]azanide;2-(1-methylbenzimidazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;5-(10-methylphenazin-5-yl)-2-(1-phenylbenzimidazol-3-ium-2-yl)phenolate;zinc.

Molecular Properties

• Compound Name: trilithium;2-(1,3-benzothiazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzothiazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzothiazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;2-(1,3-benzoxazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzoxazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzoxazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;heptyl-[5-phenoxazin-10-yl-2-(1-phenylbenzimidazol-2-yl)phenyl]azanide;2-(1-methylbenzimidazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;5-(10-methylphenazin-5-yl)-2-(1-phenylbenzimidazol-3-ium-2-yl)phenolate;zinc
• PubChem CID: 158824889
• Molecular Formula: C250H223Li3N30O12S3Zn3
• Molecular Weight: 4152.93 g/mol
• Exact Mass: 4145.53
• IUPAC Name: trilithium;2-(1,3-benzothiazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzothiazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzothiazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;2-(1,3-benzoxazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzoxazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzoxazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;heptyl-[5-phenoxazin-10-yl-2-(1-phenylbenzimidazol-2-yl)phenyl]azanide;2-(1-methylbenzimidazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;5-(10-methylphenazin-5-yl)-2-(1-phenylbenzimidazol-3-ium-2-yl)phenolate;zinc
• SMILES: CC1=C(C)N(c2ccc(-c3nc4ccccc4n3C)c(N)c2)C(C)=C(C)O1.CC1=C(C)N(c2ccc(-c3nc4ccccc4o3)c(N)c2)C(C)=C(C)O1.CC1=C(C)N(c2ccc(-c3nc4ccccc4s3)c(N)c2)C(C)=C(C)O1.CCCCCCC[N-]c1cc(N2c3ccccc3Oc3ccccc32)ccc1-c1nc2ccccc2n1-c1ccccc1.CCCCCCC[N-]c1cc(N2c3ccccc3Oc3ccccc32)ccc1-c1nc2ccccc2o1.CCCCCCC[N-]c1cc(N2c3ccccc3Oc3ccccc32)ccc1-c1nc2ccccc2s1.CN1c2ccccc2N(c2ccc(-c3[nH+]c4ccccc4n3-c3ccccc3)c([O-])c2)c2ccccc21.CN1c2ccccc2N(c2ccc(-c3[nH+]c4ccccc4o3)c([O-])c2)c2ccccc21.CN1c2ccccc2N(c2ccc(-c3[nH+]c4ccccc4s3)c([O-])c2)c2ccccc21.[Li+].[Li+].[Li+].[Zn].[Zn].[Zn]
• InChI: InChI=1S/C38H35N4O.C32H24N4O.C32H30N3O2.C32H30N3OS.C26H19N3O2.C26H19N3OS.C22H24N4O.C21H21N3O2.C21H21N3OS.3Li.3Zn/c1-2-3-4-5-15-26-39-32-27-29(41-34-20-11-13-22-36(34)43-37-23-14-12-21-35(37)41)24-25-30(32)38-40-31-18-9-10-19-33(31)42(38)28-16-7-6-8-17-28;1-34-27-15-7-9-17-29(27)35(30-18-10-8-16-28(30)34)23-19-20-24(31(37)21-23)32-33-25-13-5-6-14-26(25)36(32)22-11-3-2-4-12-22;1-2-3-4-5-12-21-33-26-22-23(19-20-24(26)32-34-25-13-6-9-16-29(25)37-32)35-27-14-7-10-17-30(27)36-31-18-11-8-15-28(31)35;1-2-3-4-5-12-21-33-26-22-23(19-20-24(26)32-34-25-13-6-11-18-31(25)37-32)35-27-14-7-9-16-29(27)36-30-17-10-8-15-28(30)35;2*1-28-20-9-3-5-11-22(20)29(23-12-6-4-10-21(23)28)17-14-15-18(24(30)16-17)26-27-19-8-2-7-13-25(19)31-26;1-13-15(3)27-16(4)14(2)26(13)17-10-11-18(19(23)12-17)22-24-20-8-6-7-9-21(20)25(22)5;2*1-12-14(3)25-15(4)13(2)24(12)16-9-10-17(18(22)11-16)21-23-19-7-5-6-8-20(19)26-21;;;;;;/h6-14,16-25,27H,2-5,15,26H2,1H3;2-21,37H,1H3;2*6-11,13-20,22H,2-5,12,21H2,1H3;2*2-16,30H,1H3;6-12H,23H2,1-5H3;2*5-11H,22H2,1-4H3;;;;;;/q-1;;2*-1;;;;;;3*+1
• InChIKey: DOBUQEPGLKGJRZ-UHFFFAOYSA-N
• XLogP: 57.55
• TPSA: 457.77 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 39
• Rotatable Bonds: 41
• Heavy Atoms: 301
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	4152.93
LogP ≤ 5	57.55
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	39

Frequently Asked Questions

What is the IUPAC name of trilithium;2-(1,3-benzothiazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzothiazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzothiazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;2-(1,3-benzoxazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzoxazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzoxazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;heptyl-[5-phenoxazin-10-yl-2-(1-phenylbenzimidazol-2-yl)phenyl]azanide;2-(1-methylbenzimidazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;5-(10-methylphenazin-5-yl)-2-(1-phenylbenzimidazol-3-ium-2-yl)phenolate;zinc?

The IUPAC name of trilithium;2-(1,3-benzothiazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzothiazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzothiazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;2-(1,3-benzoxazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzoxazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzoxazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;heptyl-[5-phenoxazin-10-yl-2-(1-phenylbenzimidazol-2-yl)phenyl]azanide;2-(1-methylbenzimidazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;5-(10-methylphenazin-5-yl)-2-(1-phenylbenzimidazol-3-ium-2-yl)phenolate;zinc (CID 158824889) is trilithium;2-(1,3-benzothiazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzothiazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzothiazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;2-(1,3-benzoxazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzoxazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzoxazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;heptyl-[5-phenoxazin-10-yl-2-(1-phenylbenzimidazol-2-yl)phenyl]azanide;2-(1-methylbenzimidazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;5-(10-methylphenazin-5-yl)-2-(1-phenylbenzimidazol-3-ium-2-yl)phenolate;zinc.

What is the SMILES notation for trilithium;2-(1,3-benzothiazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzothiazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzothiazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;2-(1,3-benzoxazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzoxazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzoxazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;heptyl-[5-phenoxazin-10-yl-2-(1-phenylbenzimidazol-2-yl)phenyl]azanide;2-(1-methylbenzimidazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;5-(10-methylphenazin-5-yl)-2-(1-phenylbenzimidazol-3-ium-2-yl)phenolate;zinc?

The canonical SMILES for trilithium;2-(1,3-benzothiazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzothiazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzothiazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;2-(1,3-benzoxazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzoxazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzoxazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;heptyl-[5-phenoxazin-10-yl-2-(1-phenylbenzimidazol-2-yl)phenyl]azanide;2-(1-methylbenzimidazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;5-(10-methylphenazin-5-yl)-2-(1-phenylbenzimidazol-3-ium-2-yl)phenolate;zinc is CC1=C(C)N(c2ccc(-c3nc4ccccc4n3C)c(N)c2)C(C)=C(C)O1.CC1=C(C)N(c2ccc(-c3nc4ccccc4o3)c(N)c2)C(C)=C(C)O1.CC1=C(C)N(c2ccc(-c3nc4ccccc4s3)c(N)c2)C(C)=C(C)O1.CCCCCCC[N-]c1cc(N2c3ccccc3Oc3ccccc32)ccc1-c1nc2ccccc2n1-c1ccccc1.CCCCCCC[N-]c1cc(N2c3ccccc3Oc3ccccc32)ccc1-c1nc2ccccc2o1.CCCCCCC[N-]c1cc(N2c3ccccc3Oc3ccccc32)ccc1-c1nc2ccccc2s1.CN1c2ccccc2N(c2ccc(-c3[nH+]c4ccccc4n3-c3ccccc3)c([O-])c2)c2ccccc21.CN1c2ccccc2N(c2ccc(-c3[nH+]c4ccccc4o3)c([O-])c2)c2ccccc21.CN1c2ccccc2N(c2ccc(-c3[nH+]c4ccccc4s3)c([O-])c2)c2ccccc21.[Li+].[Li+].[Li+].[Zn].[Zn].[Zn].

What is the InChIKey of trilithium;2-(1,3-benzothiazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzothiazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzothiazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;2-(1,3-benzoxazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzoxazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzoxazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;heptyl-[5-phenoxazin-10-yl-2-(1-phenylbenzimidazol-2-yl)phenyl]azanide;2-(1-methylbenzimidazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;5-(10-methylphenazin-5-yl)-2-(1-phenylbenzimidazol-3-ium-2-yl)phenolate;zinc?

The InChIKey is DOBUQEPGLKGJRZ-UHFFFAOYSA-N. The full InChI is InChI=1S/C38H35N4O.C32H24N4O.C32H30N3O2.C32H30N3OS.C26H19N3O2.C26H19N3OS.C22H24N4O.C21H21N3O2.C21H21N3OS.3Li.3Zn/c1-2-3-4-5-15-26-39-32-27-29(41-34-20-11-13-22-36(34)43-37-23-14-12-21-35(37)41)24-25-30(32)38-40-31-18-9-10-19-33(31)42(38)28-16-7-6-8-17-28;1-34-27-15-7-9-17-29(27)35(30-18-10-8-16-28(30)34)23-19-20-24(31(37)21-23)32-33-25-13-5-6-14-26(25)36(32)22-11-3-2-4-12-22;1-2-3-4-5-12-21-33-26-22-23(19-20-24(26)32-34-25-13-6-9-16-29(25)37-32)35-27-14-7-10-17-30(27)36-31-18-11-8-15-28(31)35;1-2-3-4-5-12-21-33-26-22-23(19-20-24(26)32-34-25-13-6-11-18-31(25)37-32)35-27-14-7-9-16-29(27)36-30-17-10-8-15-28(30)35;2*1-28-20-9-3-5-11-22(20)29(23-12-6-4-10-21(23)28)17-14-15-18(24(30)16-17)26-27-19-8-2-7-13-25(19)31-26;1-13-15(3)27-16(4)14(2)26(13)17-10-11-18(19(23)12-17)22-24-20-8-6-7-9-21(20)25(22)5;2*1-12-14(3)25-15(4)13(2)24(12)16-9-10-17(18(22)11-16)21-23-19-7-5-6-8-20(19)26-21;;;;;;/h6-14,16-25,27H,2-5,15,26H2,1H3;2-21,37H,1H3;2*6-11,13-20,22H,2-5,12,21H2,1H3;2*2-16,30H,1H3;6-12H,23H2,1-5H3;2*5-11H,22H2,1-4H3;;;;;;/q-1;;2*-1;;;;;;3*+1;;;.

What are the key properties of trilithium;2-(1,3-benzothiazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzothiazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzothiazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;2-(1,3-benzoxazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzoxazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzoxazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;heptyl-[5-phenoxazin-10-yl-2-(1-phenylbenzimidazol-2-yl)phenyl]azanide;2-(1-methylbenzimidazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;5-(10-methylphenazin-5-yl)-2-(1-phenylbenzimidazol-3-ium-2-yl)phenolate;zinc?

trilithium;2-(1,3-benzothiazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzothiazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzothiazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;2-(1,3-benzoxazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzoxazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzoxazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;heptyl-[5-phenoxazin-10-yl-2-(1-phenylbenzimidazol-2-yl)phenyl]azanide;2-(1-methylbenzimidazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;5-(10-methylphenazin-5-yl)-2-(1-phenylbenzimidazol-3-ium-2-yl)phenolate;zinc has a molecular weight of 4152.93 g/mol, XLogP of 57.55, 41 rotatable bonds, 3 hydrogen bond donors, and 39 hydrogen bond acceptors.

Where does this data come from?

All data for trilithium;2-(1,3-benzothiazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzothiazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzothiazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;2-(1,3-benzoxazol-3-ium-2-yl)-5-(10-methylphenazin-5-yl)phenolate;[2-(1,3-benzoxazol-2-yl)-5-phenoxazin-10-ylphenyl]-heptylazanide;2-(1,3-benzoxazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;heptyl-[5-phenoxazin-10-yl-2-(1-phenylbenzimidazol-2-yl)phenyl]azanide;2-(1-methylbenzimidazol-2-yl)-5-(2,3,5,6-tetramethyl-1,4-oxazin-4-yl)aniline;5-(10-methylphenazin-5-yl)-2-(1-phenylbenzimidazol-3-ium-2-yl)phenolate;zinc is sourced from PubChem (CID 158824889), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).