5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(3-methylsulfonylazetidine-1-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(morpholine-4-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(6-oxa-3-azabicyclo[3.1.1]heptane-3-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(1-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3R,4S)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[(3R,4R)-3-fluoro-4-hydroxypyrrolidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-[(3R)-oxolan-3-yl]-1,3-thiazole-2-carboxamide;5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide

C341H461F7N72O47S17 — CID 158829391

IUPAC5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(3-methylsulfonylazetidine-1-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(morpholine-4-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(6-oxa-3-azabicyclo[3.1.1]heptane-3-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(1-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3R,4S)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[(3R,4R)-3-fluoro-4-hydroxypyrrolidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-[(3R)-oxolan-3-yl]-1,3-thiazole-2-carboxamide;5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide
SMILESCC[C@@H](C)Nc1cc(C)c(-c2sc(C(=O)N3CC(S(C)(=O)=O)C3)nc2C(=O)N2CCC[C@@H]2C)cn1.CC[C@@H](C)Nc1cc(C)c(-c2sc(C(=O)N3CC4(CCO4)C3)nc2C(=O)N2CCC[C@@H]2C)cn1.CC[C@@H](C)Nc1cc(C)c(-c2sc(C(=O)N3CC4(COC4)C3)nc2C(=O)N2CCC[C@@H]2C)cn1.CC[C@@H](C)Nc1cc(C)c(-c2sc(C(=O)N3CC4CC(C3)O4)nc2C(=O)N2CCC[C@@H]2C)cn1.CC[C@@H](C)Nc1cc(C)c(-c2sc(C(=O)N3CCOCC3)nc2C(=O)N2CCC[C@@H]2C)cn1.CC[C@@H](C)Nc1cc(C)c(-c2sc(C(=O)NC3CCOCC3)nc2C(=O)N2CCC[C@@H]2C)cn1.CC[C@@H](C)Nc1cc(C)c(-c2sc(C(=O)NC3CN(S(C)(=O)=O)C3)nc2C(=O)N2CCC[C@@H]2C)cn1.C[C@H]1CCCN1C(=O)c1nc(C(=O)NC2CCOCC2)sc1-c1cnc(NC(C)(C)C)cc1C(F)F.C[C@H]1CCCN1C(=O)c1nc(C(=O)N[C@@H]2COC[C@H]2O)sc1-c1cnc(NC(C)(C)C)cc1C(F)F.C[C@H]1CCCN1C(=O)c1nc(C(=O)N[C@H]2COC[C@@H]2O)sc1-c1cnc(NC(C)(C)C)cc1C(F)F.Cc1cc(NC(C)(C)C)ncc1-c1sc(C(=O)N2C[C@@H](O)[C@H](F)C2)nc1C(=O)N1CCC[C@@H]1C.Cc1cc(NC(C)(C)C)ncc1-c1sc(C(=O)NC2CCOCC2)nc1C(=O)N1CCC[C@@H]1C.Cc1cc(NC(C)(C)C)ncc1-c1sc(C(=O)N[C@@H]2CCOC2)nc1C(=O)N1CCC[C@@H]1C.Cc1cc(NC(C)C)ncc1-c1sc(C(=O)NC2CN(S(C)(=O)=O)C2)nc1C(=O)N1CCC[C@@H]1C
InChIInChI=1S/C25H33F2N5O3S.3C25H33N5O3S.2C25H35N5O3S.2C24H31F2N5O4S.C24H32FN5O3S.C24H34N6O4S2.C24H33N5O4S2.2C24H33N5O3S.C23H32N6O4S2/c1-14-6-5-9-32(14)24(34)19-20(36-23(30-19)22(33)29-15-7-10-35-11-8-15)17-13-28-18(31-25(2,3)4)12-16(17)21(26)27;1-5-16(3)27-19-11-15(2)18(12-26-19)21-20(23(31)30-9-6-7-17(30)4)28-22(34-21)24(32)29-13-25(14-29)8-10-33-25;1-5-16(3)27-19-9-15(2)18(10-26-19)21-20(23(31)30-8-6-7-17(30)4)28-22(34-21)24(32)29-11-25(12-29)13-33-14-25;1-5-15(3)27-20-9-14(2)19(11-26-20)22-21(24(31)30-8-6-7-16(30)4)28-23(34-22)25(32)29-12-17-10-18(13-29)33-17;1-15-13-19(29-25(3,4)5)26-14-18(15)21-20(24(32)30-10-6-7-16(30)2)28-23(34-21)22(31)27-17-8-11-33-12-9-17;1-5-16(3)27-20-13-15(2)19(14-26-20)22-21(25(32)30-10-6-7-17(30)4)29-24(34-22)23(31)28-18-8-11-33-12-9-18;2*1-12-6-5-7-31(12)23(34)18-19(36-22(29-18)21(33)28-15-10-35-11-16(15)32)14-9-27-17(30-24(2,3)4)8-13(14)20(25)26;1-13-9-18(28-24(3,4)5)26-10-15(13)20-19(22(32)30-8-6-7-14(30)2)27-21(34-20)23(33)29-11-16(25)17(31)12-29;1-6-15(3)26-19-10-14(2)18(11-25-19)21-20(24(32)30-9-7-8-16(30)4)28-23(35-21)22(31)27-17-12-29(13-17)36(5,33)34;1-6-15(3)26-19-10-14(2)18(11-25-19)21-20(23(30)29-9-7-8-16(29)4)27-22(34-21)24(31)28-12-17(13-28)35(5,32)33;1-14-11-18(28-24(3,4)5)25-12-17(14)20-19(23(31)29-9-6-7-15(29)2)27-22(33-20)21(30)26-16-8-10-32-13-16;1-5-16(3)26-19-13-15(2)18(14-25-19)21-20(23(30)29-8-6-7-17(29)4)27-22(33-21)24(31)28-9-11-32-12-10-28;1-13(2)25-18-9-14(3)17(10-24-18)20-19(23(31)29-8-6-7-15(29)4)27-22(34-20)21(30)26-16-11-28(12-16)35(5,32)33/h12-15,21H,5-11H2,1-4H3,(H,28,31)(H,29,33);11-12,16-17H,5-10,13-14H2,1-4H3,(H,26,27);9-10,16-17H,5-8,11-14H2,1-4H3,(H,26,27);9,11,15-18H,5-8,10,12-13H2,1-4H3,(H,26,27);13-14,16-17H,6-12H2,1-5H3,(H,26,29)(H,27,31);13-14,16-18H,5-12H2,1-4H3,(H,26,27)(H,28,31);2*8-9,12,15-16,20,32H,5-7,10-11H2,1-4H3,(H,27,30)(H,28,33);9-10,14,16-17,31H,6-8,11-12H2,1-5H3,(H,26,28);10-11,15-17H,6-9,12-13H2,1-5H3,(H,25,26)(H,27,31);10-11,15-17H,6-9,12-13H2,1-5H3,(H,25,26);11-12,15-16H,6-10,13H2,1-5H3,(H,25,28)(H,26,30);13-14,16-17H,5-12H2,1-4H3,(H,25,26);9-10,13,15-16H,6-8,11-12H2,1-5H3,(H,24,25)(H,26,30)/t14-;2*16-,17+;15-,16+,17?,18?;16-;16-,17+;12-,15+,16+;12-,15-,16-;14-,16+,17+;3*15-,16+;16-,17+;15-/m01110100011010/s1
InChIKeyIWVWPXFXADAECE-QHVUZGLJSA-N
MW6999.02 g/mol
LogP51.54
Rot. Bonds85

About 5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(3-methylsulfonylazetidine-1-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(morpholine-4-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(6-oxa-3-azabicyclo[3.1.1]heptane-3-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(1-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3R,4S)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[(3R,4R)-3-fluoro-4-hydroxypyrrolidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-[(3R)-oxolan-3-yl]-1,3-thiazole-2-carboxamide;5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide

5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(3-methylsulfonylazetidine-1-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(morpholine-4-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(6-oxa-3-azabicyclo[3.1.1]heptane-3-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(1-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3R,4S)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[(3R,4R)-3-fluoro-4-hydroxypyrrolidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-[(3R)-oxolan-3-yl]-1,3-thiazole-2-carboxamide;5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide (PubChem CID 158829391) has the molecular formula C341H461F7N72O47S17 and a molecular weight of 6999.02 g/mol. Its IUPAC name is 5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(3-methylsulfonylazetidine-1-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(morpholine-4-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(6-oxa-3-azabicyclo[3.1.1]heptane-3-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(1-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3R,4S)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[(3R,4R)-3-fluoro-4-hydroxypyrrolidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-[(3R)-oxolan-3-yl]-1,3-thiazole-2-carboxamide;5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide.

Molecular Properties

Compound Name5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(3-methylsulfonylazetidine-1-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(morpholine-4-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(6-oxa-3-azabicyclo[3.1.1]heptane-3-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(1-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3R,4S)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[(3R,4R)-3-fluoro-4-hydroxypyrrolidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-[(3R)-oxolan-3-yl]-1,3-thiazole-2-carboxamide;5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide
PubChem CID158829391
Molecular FormulaC341H461F7N72O47S17
Molecular Weight6999.02 g/mol
Exact Mass6993.10
IUPAC Name5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(3-methylsulfonylazetidine-1-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(morpholine-4-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(6-oxa-3-azabicyclo[3.1.1]heptane-3-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(1-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3R,4S)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[(3R,4R)-3-fluoro-4-hydroxypyrrolidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-[(3R)-oxolan-3-yl]-1,3-thiazole-2-carboxamide;5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide
SMILESCC[C@@H](C)Nc1cc(C)c(-c2sc(C(=O)N3CC(S(C)(=O)=O)C3)nc2C(=O)N2CCC[C@@H]2C)cn1.CC[C@@H](C)Nc1cc(C)c(-c2sc(C(=O)N3CC4(CCO4)C3)nc2C(=O)N2CCC[C@@H]2C)cn1.CC[C@@H](C)Nc1cc(C)c(-c2sc(C(=O)N3CC4(COC4)C3)nc2C(=O)N2CCC[C@@H]2C)cn1.CC[C@@H](C)Nc1cc(C)c(-c2sc(C(=O)N3CC4CC(C3)O4)nc2C(=O)N2CCC[C@@H]2C)cn1.CC[C@@H](C)Nc1cc(C)c(-c2sc(C(=O)N3CCOCC3)nc2C(=O)N2CCC[C@@H]2C)cn1.CC[C@@H](C)Nc1cc(C)c(-c2sc(C(=O)NC3CCOCC3)nc2C(=O)N2CCC[C@@H]2C)cn1.CC[C@@H](C)Nc1cc(C)c(-c2sc(C(=O)NC3CN(S(C)(=O)=O)C3)nc2C(=O)N2CCC[C@@H]2C)cn1.C[C@H]1CCCN1C(=O)c1nc(C(=O)NC2CCOCC2)sc1-c1cnc(NC(C)(C)C)cc1C(F)F.C[C@H]1CCCN1C(=O)c1nc(C(=O)N[C@@H]2COC[C@H]2O)sc1-c1cnc(NC(C)(C)C)cc1C(F)F.C[C@H]1CCCN1C(=O)c1nc(C(=O)N[C@H]2COC[C@@H]2O)sc1-c1cnc(NC(C)(C)C)cc1C(F)F.Cc1cc(NC(C)(C)C)ncc1-c1sc(C(=O)N2C[C@@H](O)[C@H](F)C2)nc1C(=O)N1CCC[C@@H]1C.Cc1cc(NC(C)(C)C)ncc1-c1sc(C(=O)NC2CCOCC2)nc1C(=O)N1CCC[C@@H]1C.Cc1cc(NC(C)(C)C)ncc1-c1sc(C(=O)N[C@@H]2CCOC2)nc1C(=O)N1CCC[C@@H]1C.Cc1cc(NC(C)C)ncc1-c1sc(C(=O)NC2CN(S(C)(=O)=O)C2)nc1C(=O)N1CCC[C@@H]1C
InChIInChI=1S/C25H33F2N5O3S.3C25H33N5O3S.2C25H35N5O3S.2C24H31F2N5O4S.C24H32FN5O3S.C24H34N6O4S2.C24H33N5O4S2.2C24H33N5O3S.C23H32N6O4S2/c1-14-6-5-9-32(14)24(34)19-20(36-23(30-19)22(33)29-15-7-10-35-11-8-15)17-13-28-18(31-25(2,3)4)12-16(17)21(26)27;1-5-16(3)27-19-11-15(2)18(12-26-19)21-20(23(31)30-9-6-7-17(30)4)28-22(34-21)24(32)29-13-25(14-29)8-10-33-25;1-5-16(3)27-19-9-15(2)18(10-26-19)21-20(23(31)30-8-6-7-17(30)4)28-22(34-21)24(32)29-11-25(12-29)13-33-14-25;1-5-15(3)27-20-9-14(2)19(11-26-20)22-21(24(31)30-8-6-7-16(30)4)28-23(34-22)25(32)29-12-17-10-18(13-29)33-17;1-15-13-19(29-25(3,4)5)26-14-18(15)21-20(24(32)30-10-6-7-16(30)2)28-23(34-21)22(31)27-17-8-11-33-12-9-17;1-5-16(3)27-20-13-15(2)19(14-26-20)22-21(25(32)30-10-6-7-17(30)4)29-24(34-22)23(31)28-18-8-11-33-12-9-18;2*1-12-6-5-7-31(12)23(34)18-19(36-22(29-18)21(33)28-15-10-35-11-16(15)32)14-9-27-17(30-24(2,3)4)8-13(14)20(25)26;1-13-9-18(28-24(3,4)5)26-10-15(13)20-19(22(32)30-8-6-7-14(30)2)27-21(34-20)23(33)29-11-16(25)17(31)12-29;1-6-15(3)26-19-10-14(2)18(11-25-19)21-20(24(32)30-9-7-8-16(30)4)28-23(35-21)22(31)27-17-12-29(13-17)36(5,33)34;1-6-15(3)26-19-10-14(2)18(11-25-19)21-20(23(30)29-9-7-8-16(29)4)27-22(34-21)24(31)28-12-17(13-28)35(5,32)33;1-14-11-18(28-24(3,4)5)25-12-17(14)20-19(23(31)29-9-6-7-15(29)2)27-22(33-20)21(30)26-16-8-10-32-13-16;1-5-16(3)26-19-13-15(2)18(14-25-19)21-20(23(30)29-8-6-7-17(29)4)27-22(33-21)24(31)28-9-11-32-12-10-28;1-13(2)25-18-9-14(3)17(10-24-18)20-19(23(31)29-8-6-7-15(29)4)27-22(34-20)21(30)26-16-11-28(12-16)35(5,32)33/h12-15,21H,5-11H2,1-4H3,(H,28,31)(H,29,33);11-12,16-17H,5-10,13-14H2,1-4H3,(H,26,27);9-10,16-17H,5-8,11-14H2,1-4H3,(H,26,27);9,11,15-18H,5-8,10,12-13H2,1-4H3,(H,26,27);13-14,16-17H,6-12H2,1-5H3,(H,26,29)(H,27,31);13-14,16-18H,5-12H2,1-4H3,(H,26,27)(H,28,31);2*8-9,12,15-16,20,32H,5-7,10-11H2,1-4H3,(H,27,30)(H,28,33);9-10,14,16-17,31H,6-8,11-12H2,1-5H3,(H,26,28);10-11,15-17H,6-9,12-13H2,1-5H3,(H,25,26)(H,27,31);10-11,15-17H,6-9,12-13H2,1-5H3,(H,25,26);11-12,15-16H,6-10,13H2,1-5H3,(H,25,28)(H,26,30);13-14,16-17H,5-12H2,1-4H3,(H,25,26);9-10,13,15-16H,6-8,11-12H2,1-5H3,(H,24,25)(H,26,30)/t14-;2*16-,17+;15-,16+,17?,18?;16-;16-,17+;12-,15+,16+;12-,15-,16-;14-,16+,17+;3*15-,16+;16-,17+;15-/m01110100011010/s1
InChIKeyIWVWPXFXADAECE-QHVUZGLJSA-N
XLogP51.54
TPSA1430.23 Ų
H-Bond Donors25
H-Bond Acceptors103
Rotatable Bonds85
Heavy Atoms484
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5006999.02
LogP ≤ 551.54
H-Bond Donors ≤ 525
H-Bond Acceptors ≤ 10103

Analyze 5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(3-methylsulfonylazetidine-1-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(morpholine-4-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(6-oxa-3-azabicyclo[3.1.1]heptane-3-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(1-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3R,4S)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[(3R,4R)-3-fluoro-4-hydroxypyrrolidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-[(3R)-oxolan-3-yl]-1,3-thiazole-2-carboxamide;5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide with MolForge

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Related Compounds

4-(7-azabicyclo[2.2.1]heptane-7-carbonyl)-N-[(1S,3S)-3-hydroxycyclopentyl]-5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;N-[(2S)-1-hydroxybutan-2-yl]-5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;N-[(2R)-1-hydroxybutan-2-yl]-5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide
CID 162051107
5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-N-[(1S,2S)-2-hydroxycyclobutyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[(3R,4R)-3-fluoro-4-hydroxypyrrolidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-N-[(1S,2S)-2-hydroxycyclobutyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-N-[(1R,2R)-2-hydroxycyclobutyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[(3R)-3-hydroxy-3-methylpyrrolidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[(3S)-3-hydroxy-3-methylpyrrolidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone
CID 157370578
4-(7-azabicyclo[2.2.1]heptane-7-carbonyl)-5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-N-[(1S,3S)-3-hydroxycyclopentyl]-1,3-thiazole-2-carboxamide;4-(7-azabicyclo[2.2.1]heptane-7-carbonyl)-5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-N-[(1R,3R)-3-hydroxycyclopentyl]-1,3-thiazole-2-carboxamide;4-(7-azabicyclo[2.2.1]heptane-7-carbonyl)-5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;4-(7-azabicyclo[2.2.1]heptane-7-carbonyl)-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-1,3-thiazole-2-carboxamide;N-[(1R,2R)-2-hydroxycyclopropyl]-5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide
CID 159991261
4-(7-azabicyclo[2.2.1]heptane-7-carbonyl)-5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-N-[(1S,3S)-3-hydroxycyclopentyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3S)-3-hydroxycyclopentyl]-4-[hydroxy-[(2S)-2-methylpyrrolidin-1-yl]methyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;4-[(2S)-4,4-difluoro-2-methylpyrrolidine-1-carbonyl]-N-[(1S,2S)-2-hydroxycyclopentyl]-5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-1,3-thiazole-2-carboxamide;5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide
CID 159367758
4-(7-azabicyclo[2.2.1]heptane-7-carbonyl)-5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-N-[(1R,2R)-2-hydroxycyclopentyl]-1,3-thiazole-2-carboxamide;4-(7-azabicyclo[2.2.1]heptane-7-carbonyl)-5-[6-[[(1R)-1-cyclopropylethyl]amino]-4-methyl-3-pyridinyl]-N-[(1R,2R)-2-hydroxycyclopentyl]-1,3-thiazole-2-carboxamide;4-(7-azabicyclo[2.2.1]heptane-7-carbonyl)-N-[(1R,3R)-3-hydroxycyclopentyl]-5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-(1,1-dioxothian-4-yl)-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide
CID 158800123
4-(7-azabicyclo[2.2.1]heptane-7-carbonyl)-N-[(3S,4S)-4-hydroxyoxolan-3-yl]-5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-4,4-difluoro-2-methylpyrrolidine-1-carbonyl]-N-[(2S)-3-hydroxy-3-methylbutan-2-yl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-4,4-difluoro-2-methylpyrrolidine-1-carbonyl]-N-[(2R)-3-hydroxy-3-methylbutan-2-yl]-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-(3-hydroxyazetidine-1-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-N-(3-hydroxycyclobutyl)-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[3-(hydroxymethyl)azetidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone
CID 160827600
5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-4,4-difluoro-2-methylpyrrolidine-1-carbonyl]-N-[(1S,2S)-2-hydroxycyclopentyl]-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-4,4-difluoro-2-methylpyrrolidine-1-carbonyl]-N-[(1S,3S)-3-hydroxycyclopentyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(1S,3S)-3-hydroxycyclopentyl]-4-[hydroxy-[(2S)-2-methylpyrrolidin-1-yl]methyl]-1,3-thiazole-2-carboxamide;4-[(2S)-4,4-difluoro-2-methylpyrrolidine-1-carbonyl]-N-[(1S,2S)-2-hydroxycyclopentyl]-5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-1,3-thiazole-2-carboxamide;4-[(2S)-4,4-difluoro-2-methylpyrrolidine-1-carbonyl]-N-[(1S,3S)-3-hydroxycyclopentyl]-5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-1,3-thiazole-2-carboxamide
CID 160953823
5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-N-(2-hydroxycyclopentyl)-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-N-[(2R)-3-hydroxy-3-methylbutan-2-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-N-[(2R)-1-hydroxypropan-2-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[(3R)-3-hydroxypyrrolidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone
CID 158923693
5-[6-[[(2S)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-N-(3-hydroxycyclobutyl)-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-[[(2S)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-[[(2S)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-N-[(2R)-1-hydroxypropan-2-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-[[(1S)-1-cyclopropylethyl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-4,4-difluoro-2-methylpyrrolidine-1-carbonyl]-N-[(1R,2S)-2-hydroxycyclopentyl]-1,3-thiazole-2-carboxamide;5-[6-[[(1S)-1-cyclopropylethyl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-4,4-difluoro-2-methylpyrrolidine-1-carbonyl]-N-[(2S)-3-hydroxy-3-methylbutan-2-yl]-1,3-thiazole-2-carboxamide
CID 161191186
4-(7-azabicyclo[2.2.1]heptane-7-carbonyl)-5-[6-[[(1R)-1-cyclopropylethyl]amino]-4-methyl-3-pyridinyl]-N-[(1S,2S)-2-hydroxycyclopentyl]-1,3-thiazole-2-carboxamide;4-(7-azabicyclo[2.2.1]heptane-7-carbonyl)-N-[(2S)-3-hydroxy-3-methylbutan-2-yl]-5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-4,4-difluoro-2-methylpyrrolidine-1-carbonyl]-N-(3-hydroxycyclobutyl)-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(3,3,3-trideuterio-2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide;5-[6-[[(1S)-1-cyclopropylpropyl]amino]-4-methyl-3-pyridinyl]-N-[(1-hydroxycyclopropyl)methyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;4-[(2S)-4,4-difluoro-2-methylpyrrolidine-1-carbonyl]-N-(3-hydroxy-3-methylcyclobutyl)-5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-1,3-thiazole-2-carboxamide;4-[(2S)-4,4-difluoro-2-methylpyrrolidine-1-carbonyl]-N-[(2R)-1-hydroxypropan-2-yl]-5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-1,3-thiazole-2-carboxamide;4-[(2S)-4,4-difluoro-2-methylpyrrolidine-1-carbonyl]-5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-2-(3-methylsulfonylazetidine-1-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone
CID 160665750
4-(7-azabicyclo[2.2.1]heptane-7-carbonyl)-5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-N-[(2R)-1-hydroxypropan-2-yl]-1,3-thiazole-2-carboxamide;4-(7-azabicyclo[2.2.1]heptane-7-carbonyl)-N-[(3R,4R)-4-hydroxyoxolan-3-yl]-5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-1,3-thiazole-2-carboxamide;4-(7-azabicyclo[2.2.1]heptane-7-carbonyl)-N-[(2R)-1-hydroxypropan-2-yl]-5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-N-(1,1-dioxothian-4-yl)-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-N-[(1R,2R)-2-hydroxycyclopentyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-[[(2S)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-N-[(2S)-3-hydroxy-3-methylbutan-2-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide
CID 158883022
4-(7-azabicyclo[2.2.1]heptane-7-carbonyl)-5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-N-(1,1-dioxothian-4-yl)-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-4-(3,3-difluoropyrrolidine-1-carbonyl)-N-(3-hydroxycyclobutyl)-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(1R,3R)-3-hydroxycyclopentyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-4,4-difluoro-2-methylpyrrolidine-1-carbonyl]-N-[(2R)-1-hydroxypropan-2-yl]-1,3-thiazole-2-carboxamide
CID 161113032

Frequently Asked Questions

What is the IUPAC name of 5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(3-methylsulfonylazetidine-1-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(morpholine-4-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(6-oxa-3-azabicyclo[3.1.1]heptane-3-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(1-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3R,4S)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[(3R,4R)-3-fluoro-4-hydroxypyrrolidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-[(3R)-oxolan-3-yl]-1,3-thiazole-2-carboxamide;5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide?
The IUPAC name of 5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(3-methylsulfonylazetidine-1-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(morpholine-4-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(6-oxa-3-azabicyclo[3.1.1]heptane-3-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(1-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3R,4S)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[(3R,4R)-3-fluoro-4-hydroxypyrrolidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-[(3R)-oxolan-3-yl]-1,3-thiazole-2-carboxamide;5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide (CID 158829391) is 5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(3-methylsulfonylazetidine-1-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(morpholine-4-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(6-oxa-3-azabicyclo[3.1.1]heptane-3-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(1-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3R,4S)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[(3R,4R)-3-fluoro-4-hydroxypyrrolidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-[(3R)-oxolan-3-yl]-1,3-thiazole-2-carboxamide;5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide.
What is the SMILES notation for 5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(3-methylsulfonylazetidine-1-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(morpholine-4-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(6-oxa-3-azabicyclo[3.1.1]heptane-3-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(1-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3R,4S)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[(3R,4R)-3-fluoro-4-hydroxypyrrolidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-[(3R)-oxolan-3-yl]-1,3-thiazole-2-carboxamide;5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide?
The canonical SMILES for 5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(3-methylsulfonylazetidine-1-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(morpholine-4-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(6-oxa-3-azabicyclo[3.1.1]heptane-3-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(1-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3R,4S)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[(3R,4R)-3-fluoro-4-hydroxypyrrolidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-[(3R)-oxolan-3-yl]-1,3-thiazole-2-carboxamide;5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide is CC[C@@H](C)Nc1cc(C)c(-c2sc(C(=O)N3CC(S(C)(=O)=O)C3)nc2C(=O)N2CCC[C@@H]2C)cn1.CC[C@@H](C)Nc1cc(C)c(-c2sc(C(=O)N3CC4(CCO4)C3)nc2C(=O)N2CCC[C@@H]2C)cn1.CC[C@@H](C)Nc1cc(C)c(-c2sc(C(=O)N3CC4(COC4)C3)nc2C(=O)N2CCC[C@@H]2C)cn1.CC[C@@H](C)Nc1cc(C)c(-c2sc(C(=O)N3CC4CC(C3)O4)nc2C(=O)N2CCC[C@@H]2C)cn1.CC[C@@H](C)Nc1cc(C)c(-c2sc(C(=O)N3CCOCC3)nc2C(=O)N2CCC[C@@H]2C)cn1.CC[C@@H](C)Nc1cc(C)c(-c2sc(C(=O)NC3CCOCC3)nc2C(=O)N2CCC[C@@H]2C)cn1.CC[C@@H](C)Nc1cc(C)c(-c2sc(C(=O)NC3CN(S(C)(=O)=O)C3)nc2C(=O)N2CCC[C@@H]2C)cn1.C[C@H]1CCCN1C(=O)c1nc(C(=O)NC2CCOCC2)sc1-c1cnc(NC(C)(C)C)cc1C(F)F.C[C@H]1CCCN1C(=O)c1nc(C(=O)N[C@@H]2COC[C@H]2O)sc1-c1cnc(NC(C)(C)C)cc1C(F)F.C[C@H]1CCCN1C(=O)c1nc(C(=O)N[C@H]2COC[C@@H]2O)sc1-c1cnc(NC(C)(C)C)cc1C(F)F.Cc1cc(NC(C)(C)C)ncc1-c1sc(C(=O)N2C[C@@H](O)[C@H](F)C2)nc1C(=O)N1CCC[C@@H]1C.Cc1cc(NC(C)(C)C)ncc1-c1sc(C(=O)NC2CCOCC2)nc1C(=O)N1CCC[C@@H]1C.Cc1cc(NC(C)(C)C)ncc1-c1sc(C(=O)N[C@@H]2CCOC2)nc1C(=O)N1CCC[C@@H]1C.Cc1cc(NC(C)C)ncc1-c1sc(C(=O)NC2CN(S(C)(=O)=O)C2)nc1C(=O)N1CCC[C@@H]1C.
What is the InChIKey of 5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(3-methylsulfonylazetidine-1-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(morpholine-4-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(6-oxa-3-azabicyclo[3.1.1]heptane-3-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(1-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3R,4S)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[(3R,4R)-3-fluoro-4-hydroxypyrrolidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-[(3R)-oxolan-3-yl]-1,3-thiazole-2-carboxamide;5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide?
The InChIKey is IWVWPXFXADAECE-QHVUZGLJSA-N. The full InChI is InChI=1S/C25H33F2N5O3S.3C25H33N5O3S.2C25H35N5O3S.2C24H31F2N5O4S.C24H32FN5O3S.C24H34N6O4S2.C24H33N5O4S2.2C24H33N5O3S.C23H32N6O4S2/c1-14-6-5-9-32(14)24(34)19-20(36-23(30-19)22(33)29-15-7-10-35-11-8-15)17-13-28-18(31-25(2,3)4)12-16(17)21(26)27;1-5-16(3)27-19-11-15(2)18(12-26-19)21-20(23(31)30-9-6-7-17(30)4)28-22(34-21)24(32)29-13-25(14-29)8-10-33-25;1-5-16(3)27-19-9-15(2)18(10-26-19)21-20(23(31)30-8-6-7-17(30)4)28-22(34-21)24(32)29-11-25(12-29)13-33-14-25;1-5-15(3)27-20-9-14(2)19(11-26-20)22-21(24(31)30-8-6-7-16(30)4)28-23(34-22)25(32)29-12-17-10-18(13-29)33-17;1-15-13-19(29-25(3,4)5)26-14-18(15)21-20(24(32)30-10-6-7-16(30)2)28-23(34-21)22(31)27-17-8-11-33-12-9-17;1-5-16(3)27-20-13-15(2)19(14-26-20)22-21(25(32)30-10-6-7-17(30)4)29-24(34-22)23(31)28-18-8-11-33-12-9-18;2*1-12-6-5-7-31(12)23(34)18-19(36-22(29-18)21(33)28-15-10-35-11-16(15)32)14-9-27-17(30-24(2,3)4)8-13(14)20(25)26;1-13-9-18(28-24(3,4)5)26-10-15(13)20-19(22(32)30-8-6-7-14(30)2)27-21(34-20)23(33)29-11-16(25)17(31)12-29;1-6-15(3)26-19-10-14(2)18(11-25-19)21-20(24(32)30-9-7-8-16(30)4)28-23(35-21)22(31)27-17-12-29(13-17)36(5,33)34;1-6-15(3)26-19-10-14(2)18(11-25-19)21-20(23(30)29-9-7-8-16(29)4)27-22(34-21)24(31)28-12-17(13-28)35(5,32)33;1-14-11-18(28-24(3,4)5)25-12-17(14)20-19(23(31)29-9-6-7-15(29)2)27-22(33-20)21(30)26-16-8-10-32-13-16;1-5-16(3)26-19-13-15(2)18(14-25-19)21-20(23(30)29-8-6-7-17(29)4)27-22(33-21)24(31)28-9-11-32-12-10-28;1-13(2)25-18-9-14(3)17(10-24-18)20-19(23(31)29-8-6-7-15(29)4)27-22(34-20)21(30)26-16-11-28(12-16)35(5,32)33/h12-15,21H,5-11H2,1-4H3,(H,28,31)(H,29,33);11-12,16-17H,5-10,13-14H2,1-4H3,(H,26,27);9-10,16-17H,5-8,11-14H2,1-4H3,(H,26,27);9,11,15-18H,5-8,10,12-13H2,1-4H3,(H,26,27);13-14,16-17H,6-12H2,1-5H3,(H,26,29)(H,27,31);13-14,16-18H,5-12H2,1-4H3,(H,26,27)(H,28,31);2*8-9,12,15-16,20,32H,5-7,10-11H2,1-4H3,(H,27,30)(H,28,33);9-10,14,16-17,31H,6-8,11-12H2,1-5H3,(H,26,28);10-11,15-17H,6-9,12-13H2,1-5H3,(H,25,26)(H,27,31);10-11,15-17H,6-9,12-13H2,1-5H3,(H,25,26);11-12,15-16H,6-10,13H2,1-5H3,(H,25,28)(H,26,30);13-14,16-17H,5-12H2,1-4H3,(H,25,26);9-10,13,15-16H,6-8,11-12H2,1-5H3,(H,24,25)(H,26,30)/t14-;2*16-,17+;15-,16+,17?,18?;16-;16-,17+;12-,15+,16+;12-,15-,16-;14-,16+,17+;3*15-,16+;16-,17+;15-/m01110100011010/s1.
What are the key properties of 5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(3-methylsulfonylazetidine-1-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(morpholine-4-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(6-oxa-3-azabicyclo[3.1.1]heptane-3-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(1-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3R,4S)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[(3R,4R)-3-fluoro-4-hydroxypyrrolidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-[(3R)-oxolan-3-yl]-1,3-thiazole-2-carboxamide;5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide?
5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(3-methylsulfonylazetidine-1-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(morpholine-4-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(6-oxa-3-azabicyclo[3.1.1]heptane-3-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(1-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3R,4S)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[(3R,4R)-3-fluoro-4-hydroxypyrrolidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-[(3R)-oxolan-3-yl]-1,3-thiazole-2-carboxamide;5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide has a molecular weight of 6999.02 g/mol, XLogP of 51.54, 85 rotatable bonds, 25 hydrogen bond donors, and 103 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide;5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(3-methylsulfonylazetidine-1-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(morpholine-4-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(6-oxa-3-azabicyclo[3.1.1]heptane-3-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(1-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;[5-[6-[[(2R)-butan-2-yl]amino]-4-methyl-3-pyridinyl]-2-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3R,4S)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-N-[(3S,4R)-4-hydroxyoxolan-3-yl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-(difluoromethyl)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;[5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-2-[(3R,4R)-3-fluoro-4-hydroxypyrrolidine-1-carbonyl]-1,3-thiazol-4-yl]-[(2S)-2-methylpyrrolidin-1-yl]methanone;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(oxan-4-yl)-1,3-thiazole-2-carboxamide;5-[6-(tert-butylamino)-4-methyl-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-[(3R)-oxolan-3-yl]-1,3-thiazole-2-carboxamide;5-[4-methyl-6-(propan-2-ylamino)-3-pyridinyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-N-(1-methylsulfonylazetidin-3-yl)-1,3-thiazole-2-carboxamide is sourced from PubChem (CID 158829391), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).