2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propanenitrile;(2S)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;(2R)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;cis-(1S,2S)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide

C273H259Br2F4N73O14 — CID 158840598

IUPAC2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propanenitrile;(2S)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;(2R)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;cis-(1S,2S)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide
SMILESCNc1cccc(-c2cc3cc(NC(=O)[C@@H]4C[C@@H]4F)ncc3c(N)n2)c1C.CNc1cccc(-c2cc3cc(NC(=O)[C@H]4C[C@H]4F)ncc3c(N)n2)c1C.Cc1ccccc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3CC#N)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3CC#N)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(Nc3cnn(C(C)C#N)c3)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(Nc3cnn([C@@H](C)CO)c3)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(Nc3cnn([C@H](C)CO)c3)ncc2c(N)n1.Cn1cc([C@@H]2C[C@H]2C(=O)Nc2cc3cc(-c4ccccc4CCO)nc(N)c3cn2)cn1.Cn1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(-c4ccccc4CCO)nc(N)c3cn2)cn1.Nc1nc(-c2cccc3c2CCN3)cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc12.Nc1nc(-c2cccc3c2CCN3)cc2cc(NC(=O)[C@H]3C[C@H]3F)ncc12.[C-]#[N+]C[C@@H]1C[C@H]1C(=O)Nc1cc2c(Br)c(-c3cnccc3C)nc(N)c2cn1.[C-]#[N+]C[C@H]1C[C@@H]1C(=O)Nc1cc2c(Br)c(-c3cnccc3C)nc(N)c2cn1
InChIInChI=1S/2C24H24N6O2.C21H19N7.2C21H22N6O.2C21H19N5O.2C20H17BrN6O.2C20H18FN5O.2C20H20FN5O/c2*1-30-13-16(11-27-30)18-10-19(18)24(32)29-22-9-15-8-21(28-23(25)20(15)12-26-22)17-5-3-2-4-14(17)6-7-31;1-13-5-3-4-6-17(13)19-7-15-8-20(24-11-18(15)21(23)27-19)26-16-10-25-28(12-16)14(2)9-22;2*1-13-5-3-4-6-17(13)19-7-15-8-20(23-10-18(15)21(22)26-19)25-16-9-24-27(11-16)14(2)12-28;2*1-12-4-2-3-5-15(12)18-9-14-10-19(24-11-17(14)20(23)25-18)26-21(27)16-8-13(16)6-7-22;2*1-10-3-4-24-8-14(10)18-17(21)13-6-16(25-9-15(13)19(22)27-18)26-20(28)12-5-11(12)7-23-2;2*21-15-8-13(15)20(27)26-18-7-10-6-17(25-19(22)14(10)9-24-18)11-2-1-3-16-12(11)4-5-23-16;2*1-10-12(4-3-5-16(10)23-2)17-6-11-7-18(24-9-14(11)19(22)25-17)26-20(27)13-8-15(13)21/h2*2-5,8-9,11-13,18-19,31H,6-7,10H2,1H3,(H2,25,28)(H,26,29,32);3-8,10-12,14H,1-2H3,(H2,23,27)(H,24,26);2*3-11,14,28H,12H2,1-2H3,(H2,22,26)(H,23,25);2*2-5,9-11,13,16H,6,8H2,1H3,(H2,23,25)(H,24,26,27);2*3-4,6,8-9,11-12H,5,7H2,1H3,(H2,22,27)(H,25,26,28);2*1-3,6-7,9,13,15,23H,4-5,8H2,(H2,22,25)(H,24,26,27);2*3-7,9,13,15,23H,8H2,1-2H3,(H2,22,25)(H,24,26,27)/t2*18-,19+;;2*14-;2*13-,16-;2*11-,12+;4*13-,15+/m10.1010101010/s1
InChIKeyIYENROJKTXPLOD-FFLNHAMZSA-N
MW5022.37 g/mol
LogP45.72
Rot. Bonds56

About 2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propanenitrile;(2S)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;(2R)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;cis-(1S,2S)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide

2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propanenitrile;(2S)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;(2R)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;cis-(1S,2S)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide (PubChem CID 158840598) has the molecular formula C273H259Br2F4N73O14 and a molecular weight of 5022.37 g/mol. Its IUPAC name is 2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propanenitrile;(2S)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;(2R)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;cis-(1S,2S)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide.

Molecular Properties

Compound Name2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propanenitrile;(2S)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;(2R)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;cis-(1S,2S)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide
PubChem CID158840598
Molecular FormulaC273H259Br2F4N73O14
Molecular Weight5022.37 g/mol
Exact Mass5017.01
IUPAC Name2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propanenitrile;(2S)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;(2R)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;cis-(1S,2S)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide
SMILESCNc1cccc(-c2cc3cc(NC(=O)[C@@H]4C[C@@H]4F)ncc3c(N)n2)c1C.CNc1cccc(-c2cc3cc(NC(=O)[C@H]4C[C@H]4F)ncc3c(N)n2)c1C.Cc1ccccc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3CC#N)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3CC#N)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(Nc3cnn(C(C)C#N)c3)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(Nc3cnn([C@@H](C)CO)c3)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(Nc3cnn([C@H](C)CO)c3)ncc2c(N)n1.Cn1cc([C@@H]2C[C@H]2C(=O)Nc2cc3cc(-c4ccccc4CCO)nc(N)c3cn2)cn1.Cn1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(-c4ccccc4CCO)nc(N)c3cn2)cn1.Nc1nc(-c2cccc3c2CCN3)cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc12.Nc1nc(-c2cccc3c2CCN3)cc2cc(NC(=O)[C@H]3C[C@H]3F)ncc12.[C-]#[N+]C[C@@H]1C[C@H]1C(=O)Nc1cc2c(Br)c(-c3cnccc3C)nc(N)c2cn1.[C-]#[N+]C[C@H]1C[C@@H]1C(=O)Nc1cc2c(Br)c(-c3cnccc3C)nc(N)c2cn1
InChIInChI=1S/2C24H24N6O2.C21H19N7.2C21H22N6O.2C21H19N5O.2C20H17BrN6O.2C20H18FN5O.2C20H20FN5O/c2*1-30-13-16(11-27-30)18-10-19(18)24(32)29-22-9-15-8-21(28-23(25)20(15)12-26-22)17-5-3-2-4-14(17)6-7-31;1-13-5-3-4-6-17(13)19-7-15-8-20(24-11-18(15)21(23)27-19)26-16-10-25-28(12-16)14(2)9-22;2*1-13-5-3-4-6-17(13)19-7-15-8-20(23-10-18(15)21(22)26-19)25-16-9-24-27(11-16)14(2)12-28;2*1-12-4-2-3-5-15(12)18-9-14-10-19(24-11-17(14)20(23)25-18)26-21(27)16-8-13(16)6-7-22;2*1-10-3-4-24-8-14(10)18-17(21)13-6-16(25-9-15(13)19(22)27-18)26-20(28)12-5-11(12)7-23-2;2*21-15-8-13(15)20(27)26-18-7-10-6-17(25-19(22)14(10)9-24-18)11-2-1-3-16-12(11)4-5-23-16;2*1-10-12(4-3-5-16(10)23-2)17-6-11-7-18(24-9-14(11)19(22)25-17)26-20(27)13-8-15(13)21/h2*2-5,8-9,11-13,18-19,31H,6-7,10H2,1H3,(H2,25,28)(H,26,29,32);3-8,10-12,14H,1-2H3,(H2,23,27)(H,24,26);2*3-11,14,28H,12H2,1-2H3,(H2,22,26)(H,23,25);2*2-5,9-11,13,16H,6,8H2,1H3,(H2,23,25)(H,24,26,27);2*3-4,6,8-9,11-12H,5,7H2,1H3,(H2,22,27)(H,25,26,28);2*1-3,6-7,9,13,15,23H,4-5,8H2,(H2,22,25)(H,24,26,27);2*3-7,9,13,15,23H,8H2,1-2H3,(H2,22,25)(H,24,26,27)/t2*18-,19+;;2*14-;2*13-,16-;2*11-,12+;4*13-,15+/m10.1010101010/s1
InChIKeyIYENROJKTXPLOD-FFLNHAMZSA-N
XLogP45.72
TPSA1324.50 Ų
H-Bond Donors34
H-Bond Acceptors75
Rotatable Bonds56
Heavy Atoms366
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5005022.37
LogP ≤ 545.72
H-Bond Donors ≤ 534
H-Bond Acceptors ≤ 1075

Analyze 2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propanenitrile;(2S)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;(2R)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;cis-(1S,2S)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of 2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propanenitrile;(2S)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;(2R)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;cis-(1S,2S)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide?
The IUPAC name of 2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propanenitrile;(2S)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;(2R)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;cis-(1S,2S)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide (CID 158840598) is 2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propanenitrile;(2S)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;(2R)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;cis-(1S,2S)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide.
What is the SMILES notation for 2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propanenitrile;(2S)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;(2R)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;cis-(1S,2S)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide?
The canonical SMILES for 2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propanenitrile;(2S)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;(2R)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;cis-(1S,2S)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide is CNc1cccc(-c2cc3cc(NC(=O)[C@@H]4C[C@@H]4F)ncc3c(N)n2)c1C.CNc1cccc(-c2cc3cc(NC(=O)[C@H]4C[C@H]4F)ncc3c(N)n2)c1C.Cc1ccccc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3CC#N)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3CC#N)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(Nc3cnn(C(C)C#N)c3)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(Nc3cnn([C@@H](C)CO)c3)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(Nc3cnn([C@H](C)CO)c3)ncc2c(N)n1.Cn1cc([C@@H]2C[C@H]2C(=O)Nc2cc3cc(-c4ccccc4CCO)nc(N)c3cn2)cn1.Cn1cc([C@H]2C[C@@H]2C(=O)Nc2cc3cc(-c4ccccc4CCO)nc(N)c3cn2)cn1.Nc1nc(-c2cccc3c2CCN3)cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc12.Nc1nc(-c2cccc3c2CCN3)cc2cc(NC(=O)[C@H]3C[C@H]3F)ncc12.[C-]#[N+]C[C@@H]1C[C@H]1C(=O)Nc1cc2c(Br)c(-c3cnccc3C)nc(N)c2cn1.[C-]#[N+]C[C@H]1C[C@@H]1C(=O)Nc1cc2c(Br)c(-c3cnccc3C)nc(N)c2cn1.
What is the InChIKey of 2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propanenitrile;(2S)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;(2R)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;cis-(1S,2S)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide?
The InChIKey is IYENROJKTXPLOD-FFLNHAMZSA-N. The full InChI is InChI=1S/2C24H24N6O2.C21H19N7.2C21H22N6O.2C21H19N5O.2C20H17BrN6O.2C20H18FN5O.2C20H20FN5O/c2*1-30-13-16(11-27-30)18-10-19(18)24(32)29-22-9-15-8-21(28-23(25)20(15)12-26-22)17-5-3-2-4-14(17)6-7-31;1-13-5-3-4-6-17(13)19-7-15-8-20(24-11-18(15)21(23)27-19)26-16-10-25-28(12-16)14(2)9-22;2*1-13-5-3-4-6-17(13)19-7-15-8-20(23-10-18(15)21(22)26-19)25-16-9-24-27(11-16)14(2)12-28;2*1-12-4-2-3-5-15(12)18-9-14-10-19(24-11-17(14)20(23)25-18)26-21(27)16-8-13(16)6-7-22;2*1-10-3-4-24-8-14(10)18-17(21)13-6-16(25-9-15(13)19(22)27-18)26-20(28)12-5-11(12)7-23-2;2*21-15-8-13(15)20(27)26-18-7-10-6-17(25-19(22)14(10)9-24-18)11-2-1-3-16-12(11)4-5-23-16;2*1-10-12(4-3-5-16(10)23-2)17-6-11-7-18(24-9-14(11)19(22)25-17)26-20(27)13-8-15(13)21/h2*2-5,8-9,11-13,18-19,31H,6-7,10H2,1H3,(H2,25,28)(H,26,29,32);3-8,10-12,14H,1-2H3,(H2,23,27)(H,24,26);2*3-11,14,28H,12H2,1-2H3,(H2,22,26)(H,23,25);2*2-5,9-11,13,16H,6,8H2,1H3,(H2,23,25)(H,24,26,27);2*3-4,6,8-9,11-12H,5,7H2,1H3,(H2,22,27)(H,25,26,28);2*1-3,6-7,9,13,15,23H,4-5,8H2,(H2,22,25)(H,24,26,27);2*3-7,9,13,15,23H,8H2,1-2H3,(H2,22,25)(H,24,26,27)/t2*18-,19+;;2*14-;2*13-,16-;2*11-,12+;4*13-,15+/m10.1010101010/s1.
What are the key properties of 2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propanenitrile;(2S)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;(2R)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;cis-(1S,2S)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide?
2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propanenitrile;(2S)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;(2R)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;cis-(1S,2S)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide has a molecular weight of 5022.37 g/mol, XLogP of 45.72, 56 rotatable bonds, 34 hydrogen bond donors, and 75 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propanenitrile;(2S)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;(2R)-2-[4-[[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]amino]pyrazol-1-yl]propan-1-ol;cis-(1S,2S)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-5-bromo-6-(4-methyl-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-(isocyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(2,3-dihydro-1H-indol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[2-methyl-3-(methylamino)phenyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;cis-(1R,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-(cyanomethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-[2-(2-hydroxyethyl)phenyl]-2,7-naphthyridin-3-yl]-2-(1-methylpyrazol-4-yl)cyclopropane-1-carboxamide is sourced from PubChem (CID 158840598), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).