N-(1-benzothiophen-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-fluoro-4-(1,2,4-triazol-1-yl)phenyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-(1-methylbenzimidazol-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[3-(1,3-oxazol-5-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(pyrazol-1-ylmethyl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)imidazo[1,2-a]pyrazin-8-amine

C109H90FN47OS — CID 158846713

About N-(1-benzothiophen-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-fluoro-4-(1,2,4-triazol-1-yl)phenyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-(1-methylbenzimidazol-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[3-(1,3-oxazol-5-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(pyrazol-1-ylmethyl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)imidazo[1,2-a]pyrazin-8-amine

N-(1-benzothiophen-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-fluoro-4-(1,2,4-triazol-1-yl)phenyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-(1-methylbenzimidazol-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[3-(1,3-oxazol-5-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(pyrazol-1-ylmethyl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)imidazo[1,2-a]pyrazin-8-amine (PubChem CID 158846713) has the molecular formula C109H90FN47OS and a molecular weight of 2125.31 g/mol. Its IUPAC name is N-(1-benzothiophen-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-fluoro-4-(1,2,4-triazol-1-yl)phenyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-(1-methylbenzimidazol-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[3-(1,3-oxazol-5-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(pyrazol-1-ylmethyl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)imidazo[1,2-a]pyrazin-8-amine.

Molecular Properties

• Compound Name: N-(1-benzothiophen-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-fluoro-4-(1,2,4-triazol-1-yl)phenyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-(1-methylbenzimidazol-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[3-(1,3-oxazol-5-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(pyrazol-1-ylmethyl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)imidazo[1,2-a]pyrazin-8-amine
• PubChem CID: 158846713
• Molecular Formula: C109H90FN47OS
• Molecular Weight: 2125.31 g/mol
• Exact Mass: 2123.81
• IUPAC Name: N-(1-benzothiophen-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-fluoro-4-(1,2,4-triazol-1-yl)phenyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-(1-methylbenzimidazol-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[3-(1,3-oxazol-5-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(pyrazol-1-ylmethyl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)imidazo[1,2-a]pyrazin-8-amine
• SMILES: Cn1cc(-c2cnc3c(Nc4ccc(-n5cncn5)c(F)c4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4ccc(Cn5cccn5)cc4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4ccc5c(c4)ncn5C)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4ccc5sccc5c4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4cccc(-c5cnco5)c4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4cccn5ncnc45)nccn23)cn1
• InChI: InChI=1S/C20H18N8.C19H15N7O.C18H14FN9.C18H16N8.C18H14N6S.C16H13N9/c1-26-14-16(11-24-26)18-12-22-20-19(21-8-10-28(18)20)25-17-5-3-15(4-6-17)13-27-9-2-7-23-27;1-25-11-14(8-23-25)16-9-22-19-18(21-5-6-26(16)19)24-15-4-2-3-13(7-15)17-10-20-12-27-17;1-26-9-12(7-23-26)16-8-22-18-17(21-4-5-27(16)18)25-13-2-3-15(14(19)6-13)28-11-20-10-24-28;1-24-11-21-14-7-13(3-4-15(14)24)23-17-18-20-9-16(26(18)6-5-19-17)12-8-22-25(2)10-12;1-23-11-13(9-21-23)15-10-20-18-17(19-5-6-24(15)18)22-14-2-3-16-12(8-14)4-7-25-16;1-23-9-11(7-20-23)13-8-18-16-14(17-4-6-24(13)16)22-12-3-2-5-25-15(12)19-10-21-25/h2-12,14H,13H2,1H3,(H,21,25);2-12H,1H3,(H,21,24);2-11H,1H3,(H,21,25);3-11H,1-2H3,(H,19,23);2-11H,1H3,(H,19,22);2-10H,1H3,(H,17,22)
• InChIKey: IYXQXMAKNQJINK-UHFFFAOYSA-N
• XLogP: 18.00
• TPSA: 482.81 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 49
• Rotatable Bonds: 22
• Heavy Atoms: 159
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2125.31
LogP ≤ 5	18.00
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	49

Frequently Asked Questions

What is the IUPAC name of N-(1-benzothiophen-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-fluoro-4-(1,2,4-triazol-1-yl)phenyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-(1-methylbenzimidazol-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[3-(1,3-oxazol-5-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(pyrazol-1-ylmethyl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)imidazo[1,2-a]pyrazin-8-amine?

The IUPAC name of N-(1-benzothiophen-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-fluoro-4-(1,2,4-triazol-1-yl)phenyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-(1-methylbenzimidazol-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[3-(1,3-oxazol-5-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(pyrazol-1-ylmethyl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)imidazo[1,2-a]pyrazin-8-amine (CID 158846713) is N-(1-benzothiophen-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-fluoro-4-(1,2,4-triazol-1-yl)phenyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-(1-methylbenzimidazol-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[3-(1,3-oxazol-5-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(pyrazol-1-ylmethyl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)imidazo[1,2-a]pyrazin-8-amine.

What is the SMILES notation for N-(1-benzothiophen-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-fluoro-4-(1,2,4-triazol-1-yl)phenyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-(1-methylbenzimidazol-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[3-(1,3-oxazol-5-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(pyrazol-1-ylmethyl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)imidazo[1,2-a]pyrazin-8-amine?

The canonical SMILES for N-(1-benzothiophen-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-fluoro-4-(1,2,4-triazol-1-yl)phenyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-(1-methylbenzimidazol-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[3-(1,3-oxazol-5-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(pyrazol-1-ylmethyl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)imidazo[1,2-a]pyrazin-8-amine is Cn1cc(-c2cnc3c(Nc4ccc(-n5cncn5)c(F)c4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4ccc(Cn5cccn5)cc4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4ccc5c(c4)ncn5C)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4ccc5sccc5c4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4cccc(-c5cnco5)c4)nccn23)cn1.Cn1cc(-c2cnc3c(Nc4cccn5ncnc45)nccn23)cn1.

What is the InChIKey of N-(1-benzothiophen-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-fluoro-4-(1,2,4-triazol-1-yl)phenyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-(1-methylbenzimidazol-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[3-(1,3-oxazol-5-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(pyrazol-1-ylmethyl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)imidazo[1,2-a]pyrazin-8-amine?

The InChIKey is IYXQXMAKNQJINK-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H18N8.C19H15N7O.C18H14FN9.C18H16N8.C18H14N6S.C16H13N9/c1-26-14-16(11-24-26)18-12-22-20-19(21-8-10-28(18)20)25-17-5-3-15(4-6-17)13-27-9-2-7-23-27;1-25-11-14(8-23-25)16-9-22-19-18(21-5-6-26(16)19)24-15-4-2-3-13(7-15)17-10-20-12-27-17;1-26-9-12(7-23-26)16-8-22-18-17(21-4-5-27(16)18)25-13-2-3-15(14(19)6-13)28-11-20-10-24-28;1-24-11-21-14-7-13(3-4-15(14)24)23-17-18-20-9-16(26(18)6-5-19-17)12-8-22-25(2)10-12;1-23-11-13(9-21-23)15-10-20-18-17(19-5-6-24(15)18)22-14-2-3-16-12(8-14)4-7-25-16;1-23-9-11(7-20-23)13-8-18-16-14(17-4-6-24(13)16)22-12-3-2-5-25-15(12)19-10-21-25/h2-12,14H,13H2,1H3,(H,21,25);2-12H,1H3,(H,21,24);2-11H,1H3,(H,21,25);3-11H,1-2H3,(H,19,23);2-11H,1H3,(H,19,22);2-10H,1H3,(H,17,22).

What are the key properties of N-(1-benzothiophen-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-fluoro-4-(1,2,4-triazol-1-yl)phenyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-(1-methylbenzimidazol-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[3-(1,3-oxazol-5-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(pyrazol-1-ylmethyl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)imidazo[1,2-a]pyrazin-8-amine?

N-(1-benzothiophen-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-fluoro-4-(1,2,4-triazol-1-yl)phenyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-(1-methylbenzimidazol-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[3-(1,3-oxazol-5-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(pyrazol-1-ylmethyl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)imidazo[1,2-a]pyrazin-8-amine has a molecular weight of 2125.31 g/mol, XLogP of 18.00, 22 rotatable bonds, 6 hydrogen bond donors, and 49 hydrogen bond acceptors.

Where does this data come from?

All data for N-(1-benzothiophen-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-[3-fluoro-4-(1,2,4-triazol-1-yl)phenyl]-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;N-(1-methylbenzimidazol-5-yl)-3-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[3-(1,3-oxazol-5-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-[4-(pyrazol-1-ylmethyl)phenyl]imidazo[1,2-a]pyrazin-8-amine;3-(1-methylpyrazol-4-yl)-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)imidazo[1,2-a]pyrazin-8-amine is sourced from PubChem (CID 158846713), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).