About 5-[[4-[[2-amino-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methylindole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-4-methyl-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-prop-1-en-2-ylpiperidin-4-yl)propyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-5-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile
5-[[4-[[2-amino-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methylindole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-4-methyl-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-prop-1-en-2-ylpiperidin-4-yl)propyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-5-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile (PubChem CID 158852628) has the molecular formula C240H293F21N50O4S11
and a molecular weight of 4694.03 g/mol. Its IUPAC name is 5-[[4-[[2-amino-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methylindole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-4-methyl-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-prop-1-en-2-ylpiperidin-4-yl)propyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-5-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile.
Frequently Asked Questions
What is the IUPAC name of 5-[[4-[[2-amino-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methylindole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-4-methyl-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-prop-1-en-2-ylpiperidin-4-yl)propyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-5-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile?
The IUPAC name of 5-[[4-[[2-amino-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methylindole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-4-methyl-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-prop-1-en-2-ylpiperidin-4-yl)propyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-5-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile (CID 158852628) is 5-[[4-[[2-amino-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methylindole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-4-methyl-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-prop-1-en-2-ylpiperidin-4-yl)propyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-5-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile.
What is the SMILES notation for 5-[[4-[[2-amino-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methylindole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-4-methyl-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-prop-1-en-2-ylpiperidin-4-yl)propyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-5-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile?
The canonical SMILES for 5-[[4-[[2-amino-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methylindole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-4-methyl-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-prop-1-en-2-ylpiperidin-4-yl)propyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-5-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile is C=C(C)N1CCC([C@@H](C)Cn2c(C#N)cc3c(C)c(CN4CCC(Nc5nc(CC)nc6sc(CC(F)(F)F)cc56)CC4)ccc32)CC1.C=CN1CCC([C@@H](C)Cn2c(C#N)cc3c(C)c(CN4CCC(Nc5nc(C)nc6sc(CC(F)(F)F)cc56)CC4)ccc32)CC1.C=CN1CCC([C@@H](C)Cn2c(C#N)cc3c(C)c(CN4CCC(Nc5nc(CC)nc6sc(CC(F)(F)F)cc56)CC4)ccc32)CC1.C=S1(=O)CC([C@@H](C)Cn2c(C#N)cc3c(C)c(CN4CCC(Nc5nc(C)nc6sc(CC(F)(F)F)cc56)CC4)ccc32)CCN1.C=S1(=O)CCC([C@@H](C)Cn2c(C#N)cc3c(C)c(CN4CCC(Nc5nc(C)nc6sc(CC(F)(F)F)cc56)CC4)ccc32)CN1.C=S1(=O)CCC([C@@H](C)Cn2c(C#N)cc3c(C)c(CN4CCC(Nc5nc(CC)nc6sc(CC(F)(F)F)cc56)CC4)ccc32)CN1.C=S1(=O)CCC([C@@H](C)Cn2c(C#N)cc3c(C)c(CN4CCC(Nc5nc(N)nc6sc(CC(F)(F)F)cc56)CC4)ccc32)CN1.
What is the InChIKey of 5-[[4-[[2-amino-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methylindole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-4-methyl-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-prop-1-en-2-ylpiperidin-4-yl)propyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-5-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile?
The InChIKey is IZQRHAYITRGDLU-KNWVKSDYSA-N. The full InChI is InChI=1S/C37H46F3N7S.C36H44F3N7S.C35H42F3N7S.C34H42F3N7OS2.2C33H40F3N7OS2.C32H39F3N8OS2/c1-6-34-43-35(32-18-30(19-37(38,39)40)48-36(32)44-34)42-28-11-13-45(14-12-28)22-27-7-8-33-31(25(27)5)17-29(20-41)47(33)21-24(4)26-9-15-46(16-10-26)23(2)3;1-5-33-42-34(31-18-29(19-36(37,38)39)47-35(31)43-33)41-27-11-15-45(16-12-27)22-26-7-8-32-30(24(26)4)17-28(20-40)46(32)21-23(3)25-9-13-44(6-2)14-10-25;1-5-43-12-8-25(9-13-43)22(2)20-45-28(19-39)16-30-23(3)26(6-7-32(30)45)21-44-14-10-27(11-15-44)42-33-31-17-29(18-35(36,37)38)46-34(31)41-24(4)40-33;1-5-31-41-32(29-15-27(16-34(35,36)37)46-33(29)42-31)40-25-8-11-43(12-9-25)20-24-6-7-30-28(22(24)3)14-26(17-38)44(30)19-21(2)23-10-13-47(4,45)39-18-23;1-20(23-9-12-46(4,44)38-17-23)18-43-26(16-37)13-28-21(2)24(5-6-30(28)43)19-42-10-7-25(8-11-42)41-31-29-14-27(15-33(34,35)36)45-32(29)40-22(3)39-31;1-20(24-7-10-38-46(4,44)19-24)17-43-26(16-37)13-28-21(2)23(5-6-30(28)43)18-42-11-8-25(9-12-42)41-31-29-14-27(15-33(34,35)36)45-32(29)40-22(3)39-31;1-19(21-8-11-46(3,44)38-16-21)17-43-24(15-36)12-26-20(2)22(4-5-28(26)43)18-42-9-6-23(7-10-42)39-29-27-13-25(14-32(33,34)35)45-30(27)41-31(37)40-29/h7-8,17-18,24,26,28H,2,6,9-16,19,21-22H2,1,3-5H3,(H,42,43,44);6-8,17-18,23,25,27H,2,5,9-16,19,21-22H2,1,3-4H3,(H,41,42,43);5-7,16-17,22,25,27H,1,8-15,18,20-21H2,2-4H3,(H,40,41,42);6-7,14-15,21,23,25H,4-5,8-13,16,18-20H2,1-3H3,(H,39,45)(H,40,41,42);5-6,13-14,20,23,25H,4,7-12,15,17-19H2,1-3H3,(H,38,44)(H,39,40,41);5-6,13-14,20,24-25H,4,7-12,15,17-19H2,1-3H3,(H,38,44)(H,39,40,41);4-5,12-13,19,21,23H,3,6-11,14,16-18H2,1-2H3,(H,38,44)(H3,37,39,40,41)/t24-;23-;22-;21-,23?,47?;20-,23?,46?;20-,24?,46?;19-,21?,46?/m0000000/s1.
What are the key properties of 5-[[4-[[2-amino-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methylindole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-4-methyl-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-prop-1-en-2-ylpiperidin-4-yl)propyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-5-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile?
5-[[4-[[2-amino-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methylindole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-4-methyl-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-prop-1-en-2-ylpiperidin-4-yl)propyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-5-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile has a molecular weight of 4694.03 g/mol, XLogP of 48.62, 62 rotatable bonds, 12 hydrogen bond donors, and 57 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[[4-[[2-amino-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methylindole-2-carbonitrile;1-[(2R)-2-(1-ethenylpiperidin-4-yl)propyl]-4-methyl-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]indole-2-carbonitrile;5-[[4-[[2-ethyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-4-methyl-1-[(2R)-2-(1-prop-1-en-2-ylpiperidin-4-yl)propyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-4-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-[(2R)-2-(1-methylidene-1-oxothiazinan-5-yl)propyl]-5-[[4-[[2-methyl-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile is sourced from PubChem (CID 158852628), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).