6-(2-ethoxyethoxy)-N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)quinazolin-4-amine;4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-ol;2-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]oxyethanol;N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)-6-(3-methylsulfonylpropoxy)quinazolin-4-amine;6-[5-(4-methylsulfonylbutyl)furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;(2R)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxybutan-2-ol

C153H140N32O19S2 — CID 158860486

About 6-(2-ethoxyethoxy)-N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)quinazolin-4-amine;4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-ol;2-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]oxyethanol;N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)-6-(3-methylsulfonylpropoxy)quinazolin-4-amine;6-[5-(4-methylsulfonylbutyl)furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;(2R)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxybutan-2-ol

6-(2-ethoxyethoxy)-N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)quinazolin-4-amine;4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-ol;2-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]oxyethanol;N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)-6-(3-methylsulfonylpropoxy)quinazolin-4-amine;6-[5-(4-methylsulfonylbutyl)furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;(2R)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxybutan-2-ol (PubChem CID 158860486) has the molecular formula C153H140N32O19S2 and a molecular weight of 2795.14 g/mol. Its IUPAC name is 6-(2-ethoxyethoxy)-N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)quinazolin-4-amine;4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-ol;2-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]oxyethanol;N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)-6-(3-methylsulfonylpropoxy)quinazolin-4-amine;6-[5-(4-methylsulfonylbutyl)furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;(2R)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxybutan-2-ol.

Molecular Properties

• Compound Name: 6-(2-ethoxyethoxy)-N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)quinazolin-4-amine;4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-ol;2-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]oxyethanol;N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)-6-(3-methylsulfonylpropoxy)quinazolin-4-amine;6-[5-(4-methylsulfonylbutyl)furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;(2R)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxybutan-2-ol
• PubChem CID: 158860486
• Molecular Formula: C153H140N32O19S2
• Molecular Weight: 2795.14 g/mol
• Exact Mass: 2793.04
• IUPAC Name: 6-(2-ethoxyethoxy)-N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)quinazolin-4-amine;4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-ol;2-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]oxyethanol;N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)-6-(3-methylsulfonylpropoxy)quinazolin-4-amine;6-[5-(4-methylsulfonylbutyl)furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;(2R)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxybutan-2-ol
• SMILES: CCOCCOc1ccc2ncnc(Nc3ccc(Oc4ccn5ccnc5c4)c(C)c3)c2c1.CC[C@@H](O)COc1ccc2ncnc(Nc3ccc(Oc4ccn5ncnc5c4)c(C)c3)c2c1.Cc1cc(Nc2ncnc3ccc(-c4ccc(CCCCS(C)(=O)=O)o4)cc23)ccc1Oc1ccn2ncnc2c1.Cc1cc(Nc2ncnc3ccc(O)cc23)ccc1Oc1ccn2ccnc2c1.Cc1cc(Nc2ncnc3ccc(OCCCS(C)(=O)=O)cc23)ccc1Oc1ccn2ccnc2c1.Cc1cc(Nc2ncnc3ccc(OCCO)cc23)ccc1Oc1ccn2ccnc2c1
• InChI: InChI=1S/C30H28N6O4S.C26H25N5O4S.C26H25N5O3.C25H24N6O3.C24H21N5O3.C22H17N5O2/c1-20-15-22(7-10-27(20)40-24-12-13-36-29(17-24)32-19-34-36)35-30-25-16-21(6-9-26(25)31-18-33-30)28-11-8-23(39-28)5-3-4-14-41(2,37)38;1-18-14-19(4-7-24(18)35-21-8-10-31-11-9-27-25(31)16-21)30-26-22-15-20(5-6-23(22)28-17-29-26)34-12-3-13-36(2,32)33;1-3-32-12-13-33-20-5-6-23-22(15-20)26(29-17-28-23)30-19-4-7-24(18(2)14-19)34-21-8-10-31-11-9-27-25(31)16-21;1-3-18(32)13-33-19-5-6-22-21(11-19)25(28-14-26-22)30-17-4-7-23(16(2)10-17)34-20-8-9-31-24(12-20)27-15-29-31;1-16-12-17(2-5-22(16)32-19-6-8-29-9-7-25-23(29)14-19)28-24-20-13-18(31-11-10-30)3-4-21(20)26-15-27-24;1-14-10-15(26-22-18-11-16(28)3-4-19(18)24-13-25-22)2-5-20(14)29-17-6-8-27-9-7-23-21(27)12-17/h6-13,15-19H,3-5,14H2,1-2H3,(H,31,33,35);4-11,14-17H,3,12-13H2,1-2H3,(H,28,29,30);4-11,14-17H,3,12-13H2,1-2H3,(H,28,29,30);4-12,14-15,18,32H,3,13H2,1-2H3,(H,26,28,30);2-9,12-15,30H,10-11H2,1H3,(H,26,27,28);2-13,28H,1H3,(H,24,25,26)/t;;;18-;;/m...1../s1
• InChIKey: JAPAERNILVZOAT-AXHIIXHBSA-N
• XLogP: 30.60
• TPSA: 600.08 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 51
• Rotatable Bonds: 47
• Heavy Atoms: 206
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2795.14
LogP ≤ 5	30.60
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	51

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 6-(2-ethoxyethoxy)-N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)quinazolin-4-amine;4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-ol;2-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]oxyethanol;N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)-6-(3-methylsulfonylpropoxy)quinazolin-4-amine;6-[5-(4-methylsulfonylbutyl)furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;(2R)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxybutan-2-ol?

The IUPAC name of 6-(2-ethoxyethoxy)-N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)quinazolin-4-amine;4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-ol;2-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]oxyethanol;N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)-6-(3-methylsulfonylpropoxy)quinazolin-4-amine;6-[5-(4-methylsulfonylbutyl)furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;(2R)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxybutan-2-ol (CID 158860486) is 6-(2-ethoxyethoxy)-N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)quinazolin-4-amine;4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-ol;2-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]oxyethanol;N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)-6-(3-methylsulfonylpropoxy)quinazolin-4-amine;6-[5-(4-methylsulfonylbutyl)furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;(2R)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxybutan-2-ol.

What is the SMILES notation for 6-(2-ethoxyethoxy)-N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)quinazolin-4-amine;4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-ol;2-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]oxyethanol;N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)-6-(3-methylsulfonylpropoxy)quinazolin-4-amine;6-[5-(4-methylsulfonylbutyl)furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;(2R)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxybutan-2-ol?

The canonical SMILES for 6-(2-ethoxyethoxy)-N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)quinazolin-4-amine;4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-ol;2-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]oxyethanol;N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)-6-(3-methylsulfonylpropoxy)quinazolin-4-amine;6-[5-(4-methylsulfonylbutyl)furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;(2R)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxybutan-2-ol is CCOCCOc1ccc2ncnc(Nc3ccc(Oc4ccn5ccnc5c4)c(C)c3)c2c1.CC[C@@H](O)COc1ccc2ncnc(Nc3ccc(Oc4ccn5ncnc5c4)c(C)c3)c2c1.Cc1cc(Nc2ncnc3ccc(-c4ccc(CCCCS(C)(=O)=O)o4)cc23)ccc1Oc1ccn2ncnc2c1.Cc1cc(Nc2ncnc3ccc(O)cc23)ccc1Oc1ccn2ccnc2c1.Cc1cc(Nc2ncnc3ccc(OCCCS(C)(=O)=O)cc23)ccc1Oc1ccn2ccnc2c1.Cc1cc(Nc2ncnc3ccc(OCCO)cc23)ccc1Oc1ccn2ccnc2c1.

What is the InChIKey of 6-(2-ethoxyethoxy)-N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)quinazolin-4-amine;4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-ol;2-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]oxyethanol;N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)-6-(3-methylsulfonylpropoxy)quinazolin-4-amine;6-[5-(4-methylsulfonylbutyl)furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;(2R)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxybutan-2-ol?

The InChIKey is JAPAERNILVZOAT-AXHIIXHBSA-N. The full InChI is InChI=1S/C30H28N6O4S.C26H25N5O4S.C26H25N5O3.C25H24N6O3.C24H21N5O3.C22H17N5O2/c1-20-15-22(7-10-27(20)40-24-12-13-36-29(17-24)32-19-34-36)35-30-25-16-21(6-9-26(25)31-18-33-30)28-11-8-23(39-28)5-3-4-14-41(2,37)38;1-18-14-19(4-7-24(18)35-21-8-10-31-11-9-27-25(31)16-21)30-26-22-15-20(5-6-23(22)28-17-29-26)34-12-3-13-36(2,32)33;1-3-32-12-13-33-20-5-6-23-22(15-20)26(29-17-28-23)30-19-4-7-24(18(2)14-19)34-21-8-10-31-11-9-27-25(31)16-21;1-3-18(32)13-33-19-5-6-22-21(11-19)25(28-14-26-22)30-17-4-7-23(16(2)10-17)34-20-8-9-31-24(12-20)27-15-29-31;1-16-12-17(2-5-22(16)32-19-6-8-29-9-7-25-23(29)14-19)28-24-20-13-18(31-11-10-30)3-4-21(20)26-15-27-24;1-14-10-15(26-22-18-11-16(28)3-4-19(18)24-13-25-22)2-5-20(14)29-17-6-8-27-9-7-23-21(27)12-17/h6-13,15-19H,3-5,14H2,1-2H3,(H,31,33,35);4-11,14-17H,3,12-13H2,1-2H3,(H,28,29,30);4-11,14-17H,3,12-13H2,1-2H3,(H,28,29,30);4-12,14-15,18,32H,3,13H2,1-2H3,(H,26,28,30);2-9,12-15,30H,10-11H2,1H3,(H,26,27,28);2-13,28H,1H3,(H,24,25,26)/t;;;18-;;/m...1../s1.

What are the key properties of 6-(2-ethoxyethoxy)-N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)quinazolin-4-amine;4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-ol;2-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]oxyethanol;N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)-6-(3-methylsulfonylpropoxy)quinazolin-4-amine;6-[5-(4-methylsulfonylbutyl)furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;(2R)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxybutan-2-ol?

6-(2-ethoxyethoxy)-N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)quinazolin-4-amine;4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-ol;2-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]oxyethanol;N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)-6-(3-methylsulfonylpropoxy)quinazolin-4-amine;6-[5-(4-methylsulfonylbutyl)furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;(2R)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxybutan-2-ol has a molecular weight of 2795.14 g/mol, XLogP of 30.60, 47 rotatable bonds, 9 hydrogen bond donors, and 51 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(2-ethoxyethoxy)-N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)quinazolin-4-amine;4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-ol;2-[4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]oxyethanol;N-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylphenyl)-6-(3-methylsulfonylpropoxy)quinazolin-4-amine;6-[5-(4-methylsulfonylbutyl)furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine;(2R)-1-[4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]oxybutan-2-ol is sourced from PubChem (CID 158860486), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).