2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylacetamide;3-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylpropanamide;2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N-propan-2-ylacetamide;4-[6-(4-formylpiperazin-1-yl)-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2S)-2-hydroxybutyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(2-hydroxy-3,3-dimethylbutyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1S,2S)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(1-methyl-2-oxopyrrolidin-3-yl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[6-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile

C264H281N85O10 — CID 158869930

IUPAC2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylacetamide;3-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylpropanamide;2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N-propan-2-ylacetamide;4-[6-(4-formylpiperazin-1-yl)-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2S)-2-hydroxybutyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(2-hydroxy-3,3-dimethylbutyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1S,2S)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(1-methyl-2-oxopyrrolidin-3-yl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[6-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile
SMILESCC(C)NC(=O)CN1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.CC[C@H](O)CN1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.CN(C)C(=O)CCN1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.CN(C)C(=O)CN1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.CN1CCC(N2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cn5ncc(C#N)c45)cn3)CC2)C1=O.C[C@@H]([C@@H](O)c1ccccc1)N1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.C[C@H]([C@H](O)c1ccccc1)N1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.Cn1cc(-c2cc(-c3ccc(N4CCN(C=O)CC4)nc3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(CC(=O)N5CCCC5)CC4)nc3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(CC(O)C(C)(C)C)CC4)nc3)c3c(C#N)cnn3c2)cn1
InChIInChI=1S/2C30H30N8O.C27H29N9O.C27H32N8O.C26H27N9O.2C26H29N9O.C25H27N9O.C25H28N8O.C22H20N8O/c2*1-21(30(39)22-6-4-3-5-7-22)36-10-12-37(13-11-36)28-9-8-23(16-32-28)27-14-24(26-18-33-35(2)19-26)20-38-29(27)25(15-31)17-34-38;1-32-17-23(16-30-32)21-12-24(27-22(13-28)15-31-36(27)18-21)20-4-5-25(29-14-20)34-10-8-33(9-11-34)19-26(37)35-6-2-3-7-35;1-27(2,3)24(36)18-33-7-9-34(10-8-33)25-6-5-19(13-29-25)23-11-20(22-15-30-32(4)16-22)17-35-26(23)21(12-28)14-31-35;1-31-6-5-23(26(31)36)33-7-9-34(10-8-33)24-4-3-18(13-28-24)22-11-19(21-15-29-32(2)16-21)17-35-25(22)20(12-27)14-30-35;1-18(2)31-25(36)17-33-6-8-34(9-7-33)24-5-4-19(12-28-24)23-10-20(22-14-29-32(3)15-22)16-35-26(23)21(11-27)13-30-35;1-31(2)25(36)6-7-33-8-10-34(11-9-33)24-5-4-19(14-28-24)23-12-20(22-16-29-32(3)17-22)18-35-26(23)21(13-27)15-30-35;1-30(2)24(35)17-32-6-8-33(9-7-32)23-5-4-18(12-27-23)22-10-19(21-14-28-31(3)15-21)16-34-25(22)20(11-26)13-29-34;1-3-22(34)17-31-6-8-32(9-7-31)24-5-4-18(12-27-24)23-10-19(21-14-28-30(2)15-21)16-33-25(23)20(11-26)13-29-33;1-27-13-19(12-25-27)17-8-20(22-18(9-23)11-26-30(22)14-17)16-2-3-21(24-10-16)29-6-4-28(15-31)5-7-29/h2*3-9,14,16-21,30,39H,10-13H2,1-2H3;4-5,12,14-18H,2-3,6-11,19H2,1H3;5-6,11,13-17,24,36H,7-10,18H2,1-4H3;3-4,11,13-17,23H,5-10H2,1-2H3;4-5,10,12-16,18H,6-9,17H2,1-3H3,(H,31,36);4-5,12,14-18H,6-11H2,1-3H3;4-5,10,12-16H,6-9,17H2,1-3H3;4-5,10,12-16,22,34H,3,6-9,17H2,1-2H3;2-3,8,10-15H,4-7H2,1H3/t2*21-,30+;;;;;;;22-;/m10......0./s1
InChIKeyJBSHBZKHNATVSG-QIQBRWKPSA-N
MW4804.74 g/mol
LogP26.43
Rot. Bonds53

About 2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylacetamide;3-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylpropanamide;2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N-propan-2-ylacetamide;4-[6-(4-formylpiperazin-1-yl)-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2S)-2-hydroxybutyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(2-hydroxy-3,3-dimethylbutyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1S,2S)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(1-methyl-2-oxopyrrolidin-3-yl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[6-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile

2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylacetamide;3-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylpropanamide;2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N-propan-2-ylacetamide;4-[6-(4-formylpiperazin-1-yl)-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2S)-2-hydroxybutyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(2-hydroxy-3,3-dimethylbutyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1S,2S)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(1-methyl-2-oxopyrrolidin-3-yl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[6-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile (PubChem CID 158869930) has the molecular formula C264H281N85O10 and a molecular weight of 4804.74 g/mol. Its IUPAC name is 2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylacetamide;3-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylpropanamide;2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N-propan-2-ylacetamide;4-[6-(4-formylpiperazin-1-yl)-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2S)-2-hydroxybutyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(2-hydroxy-3,3-dimethylbutyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1S,2S)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(1-methyl-2-oxopyrrolidin-3-yl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[6-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile.

Molecular Properties

Compound Name2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylacetamide;3-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylpropanamide;2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N-propan-2-ylacetamide;4-[6-(4-formylpiperazin-1-yl)-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2S)-2-hydroxybutyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(2-hydroxy-3,3-dimethylbutyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1S,2S)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(1-methyl-2-oxopyrrolidin-3-yl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[6-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile
PubChem CID158869930
Molecular FormulaC264H281N85O10
Molecular Weight4804.74 g/mol
Exact Mass4801.41
IUPAC Name2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylacetamide;3-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylpropanamide;2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N-propan-2-ylacetamide;4-[6-(4-formylpiperazin-1-yl)-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2S)-2-hydroxybutyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(2-hydroxy-3,3-dimethylbutyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1S,2S)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(1-methyl-2-oxopyrrolidin-3-yl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[6-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile
SMILESCC(C)NC(=O)CN1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.CC[C@H](O)CN1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.CN(C)C(=O)CCN1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.CN(C)C(=O)CN1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.CN1CCC(N2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cn5ncc(C#N)c45)cn3)CC2)C1=O.C[C@@H]([C@@H](O)c1ccccc1)N1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.C[C@H]([C@H](O)c1ccccc1)N1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.Cn1cc(-c2cc(-c3ccc(N4CCN(C=O)CC4)nc3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(CC(=O)N5CCCC5)CC4)nc3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(CC(O)C(C)(C)C)CC4)nc3)c3c(C#N)cnn3c2)cn1
InChIInChI=1S/2C30H30N8O.C27H29N9O.C27H32N8O.C26H27N9O.2C26H29N9O.C25H27N9O.C25H28N8O.C22H20N8O/c2*1-21(30(39)22-6-4-3-5-7-22)36-10-12-37(13-11-36)28-9-8-23(16-32-28)27-14-24(26-18-33-35(2)19-26)20-38-29(27)25(15-31)17-34-38;1-32-17-23(16-30-32)21-12-24(27-22(13-28)15-31-36(27)18-21)20-4-5-25(29-14-20)34-10-8-33(9-11-34)19-26(37)35-6-2-3-7-35;1-27(2,3)24(36)18-33-7-9-34(10-8-33)25-6-5-19(13-29-25)23-11-20(22-15-30-32(4)16-22)17-35-26(23)21(12-28)14-31-35;1-31-6-5-23(26(31)36)33-7-9-34(10-8-33)24-4-3-18(13-28-24)22-11-19(21-15-29-32(2)16-21)17-35-25(22)20(12-27)14-30-35;1-18(2)31-25(36)17-33-6-8-34(9-7-33)24-5-4-19(12-28-24)23-10-20(22-14-29-32(3)15-22)16-35-26(23)21(11-27)13-30-35;1-31(2)25(36)6-7-33-8-10-34(11-9-33)24-5-4-19(14-28-24)23-12-20(22-16-29-32(3)17-22)18-35-26(23)21(13-27)15-30-35;1-30(2)24(35)17-32-6-8-33(9-7-32)23-5-4-18(12-27-23)22-10-19(21-14-28-31(3)15-21)16-34-25(22)20(11-26)13-29-34;1-3-22(34)17-31-6-8-32(9-7-31)24-5-4-18(12-27-24)23-10-19(21-14-28-30(2)15-21)16-33-25(23)20(11-26)13-29-33;1-27-13-19(12-25-27)17-8-20(22-18(9-23)11-26-30(22)14-17)16-2-3-21(24-10-16)29-6-4-28(15-31)5-7-29/h2*3-9,14,16-21,30,39H,10-13H2,1-2H3;4-5,12,14-18H,2-3,6-11,19H2,1H3;5-6,11,13-17,24,36H,7-10,18H2,1-4H3;3-4,11,13-17,23H,5-10H2,1-2H3;4-5,10,12-16,18H,6-9,17H2,1-3H3,(H,31,36);4-5,12,14-18H,6-11H2,1-3H3;4-5,10,12-16H,6-9,17H2,1-3H3;4-5,10,12-16,22,34H,3,6-9,17H2,1-2H3;2-3,8,10-15H,4-7H2,1H3/t2*21-,30+;;;;;;;22-;/m10......0./s1
InChIKeyJBSHBZKHNATVSG-QIQBRWKPSA-N
XLogP26.43
TPSA991.13 Ų
H-Bond Donors5
H-Bond Acceptors89
Rotatable Bonds53
Heavy Atoms359
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5004804.74
LogP ≤ 526.43
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1089

Analyze 2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylacetamide;3-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylpropanamide;2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N-propan-2-ylacetamide;4-[6-(4-formylpiperazin-1-yl)-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2S)-2-hydroxybutyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(2-hydroxy-3,3-dimethylbutyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1S,2S)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(1-methyl-2-oxopyrrolidin-3-yl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[6-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile with MolForge

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Frequently Asked Questions

What is the IUPAC name of 2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylacetamide;3-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylpropanamide;2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N-propan-2-ylacetamide;4-[6-(4-formylpiperazin-1-yl)-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2S)-2-hydroxybutyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(2-hydroxy-3,3-dimethylbutyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1S,2S)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(1-methyl-2-oxopyrrolidin-3-yl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[6-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile?
The IUPAC name of 2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylacetamide;3-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylpropanamide;2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N-propan-2-ylacetamide;4-[6-(4-formylpiperazin-1-yl)-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2S)-2-hydroxybutyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(2-hydroxy-3,3-dimethylbutyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1S,2S)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(1-methyl-2-oxopyrrolidin-3-yl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[6-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile (CID 158869930) is 2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylacetamide;3-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylpropanamide;2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N-propan-2-ylacetamide;4-[6-(4-formylpiperazin-1-yl)-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2S)-2-hydroxybutyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(2-hydroxy-3,3-dimethylbutyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1S,2S)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(1-methyl-2-oxopyrrolidin-3-yl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[6-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile.
What is the SMILES notation for 2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylacetamide;3-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylpropanamide;2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N-propan-2-ylacetamide;4-[6-(4-formylpiperazin-1-yl)-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2S)-2-hydroxybutyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(2-hydroxy-3,3-dimethylbutyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1S,2S)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(1-methyl-2-oxopyrrolidin-3-yl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[6-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile?
The canonical SMILES for 2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylacetamide;3-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylpropanamide;2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N-propan-2-ylacetamide;4-[6-(4-formylpiperazin-1-yl)-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2S)-2-hydroxybutyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(2-hydroxy-3,3-dimethylbutyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1S,2S)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(1-methyl-2-oxopyrrolidin-3-yl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[6-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile is CC(C)NC(=O)CN1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.CC[C@H](O)CN1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.CN(C)C(=O)CCN1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.CN(C)C(=O)CN1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.CN1CCC(N2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cn5ncc(C#N)c45)cn3)CC2)C1=O.C[C@@H]([C@@H](O)c1ccccc1)N1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.C[C@H]([C@H](O)c1ccccc1)N1CCN(c2ccc(-c3cc(-c4cnn(C)c4)cn4ncc(C#N)c34)cn2)CC1.Cn1cc(-c2cc(-c3ccc(N4CCN(C=O)CC4)nc3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(CC(=O)N5CCCC5)CC4)nc3)c3c(C#N)cnn3c2)cn1.Cn1cc(-c2cc(-c3ccc(N4CCN(CC(O)C(C)(C)C)CC4)nc3)c3c(C#N)cnn3c2)cn1.
What is the InChIKey of 2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylacetamide;3-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylpropanamide;2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N-propan-2-ylacetamide;4-[6-(4-formylpiperazin-1-yl)-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2S)-2-hydroxybutyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(2-hydroxy-3,3-dimethylbutyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1S,2S)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(1-methyl-2-oxopyrrolidin-3-yl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[6-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile?
The InChIKey is JBSHBZKHNATVSG-QIQBRWKPSA-N. The full InChI is InChI=1S/2C30H30N8O.C27H29N9O.C27H32N8O.C26H27N9O.2C26H29N9O.C25H27N9O.C25H28N8O.C22H20N8O/c2*1-21(30(39)22-6-4-3-5-7-22)36-10-12-37(13-11-36)28-9-8-23(16-32-28)27-14-24(26-18-33-35(2)19-26)20-38-29(27)25(15-31)17-34-38;1-32-17-23(16-30-32)21-12-24(27-22(13-28)15-31-36(27)18-21)20-4-5-25(29-14-20)34-10-8-33(9-11-34)19-26(37)35-6-2-3-7-35;1-27(2,3)24(36)18-33-7-9-34(10-8-33)25-6-5-19(13-29-25)23-11-20(22-15-30-32(4)16-22)17-35-26(23)21(12-28)14-31-35;1-31-6-5-23(26(31)36)33-7-9-34(10-8-33)24-4-3-18(13-28-24)22-11-19(21-15-29-32(2)16-21)17-35-25(22)20(12-27)14-30-35;1-18(2)31-25(36)17-33-6-8-34(9-7-33)24-5-4-19(12-28-24)23-10-20(22-14-29-32(3)15-22)16-35-26(23)21(11-27)13-30-35;1-31(2)25(36)6-7-33-8-10-34(11-9-33)24-5-4-19(14-28-24)23-12-20(22-16-29-32(3)17-22)18-35-26(23)21(13-27)15-30-35;1-30(2)24(35)17-32-6-8-33(9-7-32)23-5-4-18(12-27-23)22-10-19(21-14-28-31(3)15-21)16-34-25(22)20(11-26)13-29-34;1-3-22(34)17-31-6-8-32(9-7-31)24-5-4-18(12-27-24)23-10-19(21-14-28-30(2)15-21)16-33-25(23)20(11-26)13-29-33;1-27-13-19(12-25-27)17-8-20(22-18(9-23)11-26-30(22)14-17)16-2-3-21(24-10-16)29-6-4-28(15-31)5-7-29/h2*3-9,14,16-21,30,39H,10-13H2,1-2H3;4-5,12,14-18H,2-3,6-11,19H2,1H3;5-6,11,13-17,24,36H,7-10,18H2,1-4H3;3-4,11,13-17,23H,5-10H2,1-2H3;4-5,10,12-16,18H,6-9,17H2,1-3H3,(H,31,36);4-5,12,14-18H,6-11H2,1-3H3;4-5,10,12-16H,6-9,17H2,1-3H3;4-5,10,12-16,22,34H,3,6-9,17H2,1-2H3;2-3,8,10-15H,4-7H2,1H3/t2*21-,30+;;;;;;;22-;/m10......0./s1.
What are the key properties of 2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylacetamide;3-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylpropanamide;2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N-propan-2-ylacetamide;4-[6-(4-formylpiperazin-1-yl)-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2S)-2-hydroxybutyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(2-hydroxy-3,3-dimethylbutyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1S,2S)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(1-methyl-2-oxopyrrolidin-3-yl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[6-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile?
2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylacetamide;3-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylpropanamide;2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N-propan-2-ylacetamide;4-[6-(4-formylpiperazin-1-yl)-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2S)-2-hydroxybutyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(2-hydroxy-3,3-dimethylbutyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1S,2S)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(1-methyl-2-oxopyrrolidin-3-yl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[6-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile has a molecular weight of 4804.74 g/mol, XLogP of 26.43, 53 rotatable bonds, 5 hydrogen bond donors, and 89 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylacetamide;3-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N,N-dimethylpropanamide;2-[4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]piperazin-1-yl]-N-propan-2-ylacetamide;4-[6-(4-formylpiperazin-1-yl)-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2S)-2-hydroxybutyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(2-hydroxy-3,3-dimethylbutyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(1S,2S)-1-hydroxy-1-phenylpropan-2-yl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(1-methyl-2-oxopyrrolidin-3-yl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[6-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile is sourced from PubChem (CID 158869930), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).