N-[6-(4-benzyl-5-oxo-1,4-diazepan-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-(4-benzyl-3-oxopiperazin-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-(benzylsulfamoyl)piperidin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[hydroxy(phenyl)methyl]piperidin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide

C144H157F15N30O16S — CID 158878753

IUPACN-[6-(4-benzyl-5-oxo-1,4-diazepan-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-(4-benzyl-3-oxopiperazin-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-(benzylsulfamoyl)piperidin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[hydroxy(phenyl)methyl]piperidin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide
SMILESCC1CCCN(c2nc(C(F)(F)F)c(C(=O)Nc3ccc(N4CCC(=O)N(Cc5ccccc5)CC4)nc3)o2)C1.CC1CCCN(c2nc(C(F)(F)F)c(C(=O)Nc3ccc(N4CCC(C(O)c5ccccc5)CC4)nc3)o2)C1.CC1CCCN(c2nc(C(F)(F)F)c(C(=O)Nc3ccc(N4CCC(n5c(=O)[nH]c6ccccc65)CC4)nc3)o2)C1.CC1CCCN(c2nc(C(F)(F)F)c(C(=O)Nc3ccc(N4CCN(Cc5ccccc5)C(=O)C4)nc3)o2)C1.O=C(Nc1ccc(N2CCC(S(=O)(=O)NCc3ccccc3)CC2)nc1)c1oc(N2CCC(c3ccccc3)CC2)nc1C(F)(F)F
InChIInChI=1S/C33H35F3N6O4S.C28H30F3N7O3.C28H31F3N6O3.C28H32F3N5O3.C27H29F3N6O3/c34-33(35,36)30-29(46-32(40-30)42-17-13-25(14-18-42)24-9-5-2-6-10-24)31(43)39-26-11-12-28(37-22-26)41-19-15-27(16-20-41)47(44,45)38-21-23-7-3-1-4-8-23;1-17-5-4-12-37(16-17)27-35-24(28(29,30)31)23(41-27)25(39)33-18-8-9-22(32-15-18)36-13-10-19(11-14-36)38-21-7-3-2-6-20(21)34-26(38)40;1-19-6-5-12-37(17-19)27-34-25(28(29,30)31)24(40-27)26(39)33-21-9-10-22(32-16-21)35-13-11-23(38)36(15-14-35)18-20-7-3-2-4-8-20;1-18-6-5-13-36(17-18)27-34-25(28(29,30)31)24(39-27)26(38)33-21-9-10-22(32-16-21)35-14-11-20(12-15-35)23(37)19-7-3-2-4-8-19;1-18-6-5-11-36(15-18)26-33-24(27(28,29)30)23(39-26)25(38)32-20-9-10-21(31-14-20)34-12-13-35(22(37)17-34)16-19-7-3-2-4-8-19/h1-12,22,25,27,38H,13-21H2,(H,39,43);2-3,6-9,15,17,19H,4-5,10-14,16H2,1H3,(H,33,39)(H,34,40);2-4,7-10,16,19H,5-6,11-15,17-18H2,1H3,(H,33,39);2-4,7-10,16,18,20,23,37H,5-6,11-15,17H2,1H3,(H,33,38);2-4,7-10,14,18H,5-6,11-13,15-17H2,1H3,(H,32,38)
InChIKeyJCTRKCZNRXHHMH-UHFFFAOYSA-N
MW2881.07 g/mol
LogP25.64
Rot. Bonds32

About N-[6-(4-benzyl-5-oxo-1,4-diazepan-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-(4-benzyl-3-oxopiperazin-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-(benzylsulfamoyl)piperidin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[hydroxy(phenyl)methyl]piperidin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide

N-[6-(4-benzyl-5-oxo-1,4-diazepan-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-(4-benzyl-3-oxopiperazin-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-(benzylsulfamoyl)piperidin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[hydroxy(phenyl)methyl]piperidin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide (PubChem CID 158878753) has the molecular formula C144H157F15N30O16S and a molecular weight of 2881.07 g/mol. Its IUPAC name is N-[6-(4-benzyl-5-oxo-1,4-diazepan-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-(4-benzyl-3-oxopiperazin-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-(benzylsulfamoyl)piperidin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[hydroxy(phenyl)methyl]piperidin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide.

Molecular Properties

Compound NameN-[6-(4-benzyl-5-oxo-1,4-diazepan-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-(4-benzyl-3-oxopiperazin-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-(benzylsulfamoyl)piperidin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[hydroxy(phenyl)methyl]piperidin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide
PubChem CID158878753
Molecular FormulaC144H157F15N30O16S
Molecular Weight2881.07 g/mol
Exact Mass2879.19
IUPAC NameN-[6-(4-benzyl-5-oxo-1,4-diazepan-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-(4-benzyl-3-oxopiperazin-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-(benzylsulfamoyl)piperidin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[hydroxy(phenyl)methyl]piperidin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide
SMILESCC1CCCN(c2nc(C(F)(F)F)c(C(=O)Nc3ccc(N4CCC(=O)N(Cc5ccccc5)CC4)nc3)o2)C1.CC1CCCN(c2nc(C(F)(F)F)c(C(=O)Nc3ccc(N4CCC(C(O)c5ccccc5)CC4)nc3)o2)C1.CC1CCCN(c2nc(C(F)(F)F)c(C(=O)Nc3ccc(N4CCC(n5c(=O)[nH]c6ccccc65)CC4)nc3)o2)C1.CC1CCCN(c2nc(C(F)(F)F)c(C(=O)Nc3ccc(N4CCN(Cc5ccccc5)C(=O)C4)nc3)o2)C1.O=C(Nc1ccc(N2CCC(S(=O)(=O)NCc3ccccc3)CC2)nc1)c1oc(N2CCC(c3ccccc3)CC2)nc1C(F)(F)F
InChIInChI=1S/C33H35F3N6O4S.C28H30F3N7O3.C28H31F3N6O3.C28H32F3N5O3.C27H29F3N6O3/c34-33(35,36)30-29(46-32(40-30)42-17-13-25(14-18-42)24-9-5-2-6-10-24)31(43)39-26-11-12-28(37-22-26)41-19-15-27(16-20-41)47(44,45)38-21-23-7-3-1-4-8-23;1-17-5-4-12-37(16-17)27-35-24(28(29,30)31)23(41-27)25(39)33-18-8-9-22(32-15-18)36-13-10-19(11-14-36)38-21-7-3-2-6-20(21)34-26(38)40;1-19-6-5-12-37(17-19)27-34-25(28(29,30)31)24(40-27)26(39)33-21-9-10-22(32-16-21)35-13-11-23(38)36(15-14-35)18-20-7-3-2-4-8-20;1-18-6-5-13-36(17-18)27-34-25(28(29,30)31)24(39-27)26(38)33-21-9-10-22(32-16-21)35-14-11-20(12-15-35)23(37)19-7-3-2-4-8-19;1-18-6-5-11-36(15-18)26-33-24(27(28,29)30)23(39-26)25(38)32-20-9-10-21(31-14-20)34-12-13-35(22(37)17-34)16-19-7-3-2-4-8-19/h1-12,22,25,27,38H,13-21H2,(H,39,43);2-3,6-9,15,17,19H,4-5,10-14,16H2,1H3,(H,33,39)(H,34,40);2-4,7-10,16,19H,5-6,11-15,17-18H2,1H3,(H,33,39);2-4,7-10,16,18,20,23,37H,5-6,11-15,17H2,1H3,(H,33,38);2-4,7-10,14,18H,5-6,11-13,15-17H2,1H3,(H,32,38)
InChIKeyJCTRKCZNRXHHMH-UHFFFAOYSA-N
XLogP25.64
TPSA517.31 Ų
H-Bond Donors8
H-Bond Acceptors37
Rotatable Bonds32
Heavy Atoms206
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002881.07
LogP ≤ 525.64
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1037

Analyze N-[6-(4-benzyl-5-oxo-1,4-diazepan-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-(4-benzyl-3-oxopiperazin-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-(benzylsulfamoyl)piperidin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[hydroxy(phenyl)methyl]piperidin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide with MolForge

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Launch Full Analysis

Related Compounds

N-[6-[4-[amino(2,3-dihydro-1H-indol-2-yl)methyl]piperazin-1-yl]-3-pyridinyl]-2-[4-[4-[4-[1-hydroxy-2-[4-[5-[[2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carbonyl]amino]-2-pyridinyl]piperazin-1-yl]-2-oxoethyl]cyclohexyl]phenyl]piperidin-1-yl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide
CID 90757598
N-[6-[4-[2-(3,5-difluorophenyl)-2-hydroxyacetyl]-1,4-diazepan-1-yl]pyridin-3-yl]-2-[4-[4-[4-fluoro-3-[2-oxo-2-[4-[5-[[2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carbonyl]amino]pyridin-2-yl]piperazin-1-yl]ethyl]phenyl]phenyl]piperidin-1-yl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide
CID 91063345
(2R)-2-cyclohexyl-2-hydroxy-1-[4-[5-[2-[2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazol-5-yl]-2-oxoethyl]-2-pyridinyl]piperazin-1-yl]ethanone;3,3-difluoro-2-hydroxy-1-[4-[5-[2-[2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazol-5-yl]-2-oxoethyl]-2-pyridinyl]-1,4-diazepan-1-yl]butan-1-one;3,3-difluoro-2-hydroxy-1-[4-[5-[2-[2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazol-5-yl]-2-oxoethyl]-2-pyridinyl]piperazin-1-yl]butan-1-one;2-[6-[4-(2,3-dihydro-1H-indole-2-carbonyl)piperazin-1-yl]-3-pyridinyl]-1-[2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazol-5-yl]ethanone;(2R)-2-hydroxy-1-[4-[5-[2-[2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazol-5-yl]-2-oxoethyl]-2-pyridinyl]piperazin-1-yl]-2-phenylethanone;(2R)-2-hydroxy-1-[4-[5-[2-oxo-2-[2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazol-5-yl]ethyl]-2-pyridinyl]piperazin-1-yl]-2-phenylethanone
CID 157866263
2-[6-(4-benzyl-5-methylidene-1,4-diazepan-1-yl)-3-pyridinyl]-1-[2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazol-5-yl]ethanone;1-benzyl-4-[5-[2-[2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazol-5-yl]-2-oxoethyl]-2-pyridinyl]piperazin-2-one;N-benzyl-1-[5-[2-oxo-2-[2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazol-5-yl]ethyl]-2-pyridinyl]piperidine-4-sulfonamide;1-[1-[5-[2-[2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazol-5-yl]-2-oxoethyl]-2-pyridinyl]piperidin-4-yl]-3H-indol-2-one;1-[2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazol-5-yl]-2-[6-[4-(1-phenylethyl)piperidin-1-yl]-3-pyridinyl]ethanone
CID 157881588
N-[6-[4-(benzylsulfamoyl)piperidin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(diethylamino)-N-[6-(4-phenylpiperidin-1-yl)-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-[4-(2-phenylethyl)piperidin-1-yl]-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-(4-phenylmethoxypiperidin-1-yl)-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-phenylpiperidin-1-yl)-N-[6-(4-phenylpiperidin-1-yl)-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-(4-phenylpiperidin-1-yl)-3-pyridinyl]-2-pyrrolidin-1-yl-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide
CID 158512496
N-[6-[4-[(2R)-2-cyclohexyl-2-hydroxyacetyl]piperazin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[2-(3,5-difluorophenyl)-2-hydroxyacetyl]-1,4-diazepan-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-(2,3-dihydro-1H-indole-2-carbonyl)piperazin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[2-(2-fluorophenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide
CID 158899626
N-[6-[4-(benzylsulfamoyl)piperidin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;cyclopentyl 4-[5-[[2-pyrrolidin-1-yl-4-(trifluoromethyl)-1,3-oxazole-5-carbonyl]amino]-2-pyridinyl]piperazine-1-carboxylate;N-[6-[4-[hydroxy(phenyl)methyl]piperidin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-[4-(2-phenylethyl)piperidin-1-yl]-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-(4-phenylmethoxypiperidin-1-yl)-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide
CID 159037695
2-(3-Fluoro-5-methylphenyl)-2-hydroxy-1-[4-[5-[2-oxo-2-[2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazol-5-yl]ethyl]-2-pyridinyl]-1,4-diazepan-1-yl]ethanone;2-[6-[4-[2-(2-fluorophenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-1-[2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazol-5-yl]ethanone;2-[6-[4-[2-(2-hydroxyphenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-1-[2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazol-5-yl]ethanone;1-[2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazol-5-yl]-2-[6-[4-(1,2,3,4-tetrahydronaphthalene-1-carbonyl)piperazin-1-yl]-3-pyridinyl]ethanone;1-[2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazol-5-yl]-2-[6-[4-(1,2,3,4-tetrahydroquinoline-2-carbonyl)piperazin-1-yl]-3-pyridinyl]ethanone
CID 159099413
N-[4-[4-[(2-methoxyphenyl)carbamoyl]phenyl]phenyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-(3-methyl-2-oxobenzimidazol-1-yl)piperidin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-(3-methyl-2-oxobenzimidazol-1-yl)piperidin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[4-[4-[(2-methylphenyl)carbamoyl]phenyl]phenyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[4-[4-[(2-methylphenyl)carbamoyl]phenyl]phenyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide
CID 159101787
1-(2-Fluorophenyl)-3-[1-[5-[2-[2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazol-5-yl]-2-oxoethyl]-2-pyridinyl]azetidin-3-yl]urea;2-[6-[4-[4-(1-hydroxyethenyl)cyclohexanecarbonyl]-1,4-diazepan-1-yl]-3-pyridinyl]-1-[2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazol-5-yl]ethanone;1-methyl-3-[1-[5-[2-[2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazol-5-yl]-2-oxoethyl]-2-pyridinyl]piperidin-4-yl]benzimidazol-2-one;1-methyl-3-[1-[5-[2-oxo-2-[2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazol-5-yl]ethyl]-2-pyridinyl]piperidin-4-yl]benzimidazol-2-one
CID 159224843
N-[6-(4-benzoylpiperidin-1-yl)-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-(4-benzyl-5-oxo-1,4-diazepan-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-(benzylsulfamoyl)piperidin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide
CID 160088332
N-[6-[4-(4-acetylcyclohexanecarbonyl)piperazin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[(2-fluorophenyl)carbamoyl]piperazin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[2-(2-fluorophenyl)-2-oxoethyl]piperazin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-[[4-[5-[[2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carbonyl]amino]-2-pyridinyl]piperazine-1-carbonyl]amino]benzoic acid;2-[[4-[5-[[2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carbonyl]amino]-2-pyridinyl]piperazine-1-carbonyl]amino]benzoic acid
CID 160367095

Frequently Asked Questions

What is the IUPAC name of N-[6-(4-benzyl-5-oxo-1,4-diazepan-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-(4-benzyl-3-oxopiperazin-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-(benzylsulfamoyl)piperidin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[hydroxy(phenyl)methyl]piperidin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide?
The IUPAC name of N-[6-(4-benzyl-5-oxo-1,4-diazepan-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-(4-benzyl-3-oxopiperazin-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-(benzylsulfamoyl)piperidin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[hydroxy(phenyl)methyl]piperidin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide (CID 158878753) is N-[6-(4-benzyl-5-oxo-1,4-diazepan-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-(4-benzyl-3-oxopiperazin-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-(benzylsulfamoyl)piperidin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[hydroxy(phenyl)methyl]piperidin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide.
What is the SMILES notation for N-[6-(4-benzyl-5-oxo-1,4-diazepan-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-(4-benzyl-3-oxopiperazin-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-(benzylsulfamoyl)piperidin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[hydroxy(phenyl)methyl]piperidin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide?
The canonical SMILES for N-[6-(4-benzyl-5-oxo-1,4-diazepan-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-(4-benzyl-3-oxopiperazin-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-(benzylsulfamoyl)piperidin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[hydroxy(phenyl)methyl]piperidin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide is CC1CCCN(c2nc(C(F)(F)F)c(C(=O)Nc3ccc(N4CCC(=O)N(Cc5ccccc5)CC4)nc3)o2)C1.CC1CCCN(c2nc(C(F)(F)F)c(C(=O)Nc3ccc(N4CCC(C(O)c5ccccc5)CC4)nc3)o2)C1.CC1CCCN(c2nc(C(F)(F)F)c(C(=O)Nc3ccc(N4CCC(n5c(=O)[nH]c6ccccc65)CC4)nc3)o2)C1.CC1CCCN(c2nc(C(F)(F)F)c(C(=O)Nc3ccc(N4CCN(Cc5ccccc5)C(=O)C4)nc3)o2)C1.O=C(Nc1ccc(N2CCC(S(=O)(=O)NCc3ccccc3)CC2)nc1)c1oc(N2CCC(c3ccccc3)CC2)nc1C(F)(F)F.
What is the InChIKey of N-[6-(4-benzyl-5-oxo-1,4-diazepan-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-(4-benzyl-3-oxopiperazin-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-(benzylsulfamoyl)piperidin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[hydroxy(phenyl)methyl]piperidin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide?
The InChIKey is JCTRKCZNRXHHMH-UHFFFAOYSA-N. The full InChI is InChI=1S/C33H35F3N6O4S.C28H30F3N7O3.C28H31F3N6O3.C28H32F3N5O3.C27H29F3N6O3/c34-33(35,36)30-29(46-32(40-30)42-17-13-25(14-18-42)24-9-5-2-6-10-24)31(43)39-26-11-12-28(37-22-26)41-19-15-27(16-20-41)47(44,45)38-21-23-7-3-1-4-8-23;1-17-5-4-12-37(16-17)27-35-24(28(29,30)31)23(41-27)25(39)33-18-8-9-22(32-15-18)36-13-10-19(11-14-36)38-21-7-3-2-6-20(21)34-26(38)40;1-19-6-5-12-37(17-19)27-34-25(28(29,30)31)24(40-27)26(39)33-21-9-10-22(32-16-21)35-13-11-23(38)36(15-14-35)18-20-7-3-2-4-8-20;1-18-6-5-13-36(17-18)27-34-25(28(29,30)31)24(39-27)26(38)33-21-9-10-22(32-16-21)35-14-11-20(12-15-35)23(37)19-7-3-2-4-8-19;1-18-6-5-11-36(15-18)26-33-24(27(28,29)30)23(39-26)25(38)32-20-9-10-21(31-14-20)34-12-13-35(22(37)17-34)16-19-7-3-2-4-8-19/h1-12,22,25,27,38H,13-21H2,(H,39,43);2-3,6-9,15,17,19H,4-5,10-14,16H2,1H3,(H,33,39)(H,34,40);2-4,7-10,16,19H,5-6,11-15,17-18H2,1H3,(H,33,39);2-4,7-10,16,18,20,23,37H,5-6,11-15,17H2,1H3,(H,33,38);2-4,7-10,14,18H,5-6,11-13,15-17H2,1H3,(H,32,38).
What are the key properties of N-[6-(4-benzyl-5-oxo-1,4-diazepan-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-(4-benzyl-3-oxopiperazin-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-(benzylsulfamoyl)piperidin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[hydroxy(phenyl)methyl]piperidin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide?
N-[6-(4-benzyl-5-oxo-1,4-diazepan-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-(4-benzyl-3-oxopiperazin-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-(benzylsulfamoyl)piperidin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[hydroxy(phenyl)methyl]piperidin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide has a molecular weight of 2881.07 g/mol, XLogP of 25.64, 32 rotatable bonds, 8 hydrogen bond donors, and 37 hydrogen bond acceptors.
Where does this data come from?
All data for N-[6-(4-benzyl-5-oxo-1,4-diazepan-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-(4-benzyl-3-oxopiperazin-1-yl)-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-(benzylsulfamoyl)piperidin-1-yl]-3-pyridinyl]-2-(4-phenylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;N-[6-[4-[hydroxy(phenyl)methyl]piperidin-1-yl]-3-pyridinyl]-2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide;2-(3-methylpiperidin-1-yl)-N-[6-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]-3-pyridinyl]-4-(trifluoromethyl)-1,3-oxazole-5-carboxamide is sourced from PubChem (CID 158878753), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).