4-(8-anilinoimidazo[1,2-a]pyrazin-6-yl)-N-(2-hydroxyethyl)benzamide;3-[8-(cyclopropylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;4-[8-(cyclopropylmethylamino)imidazo[1,2-a]pyrazin-6-yl]-2-methoxyphenol;3-[8-(ethylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;N-phenyl-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine

C84H78N22O6 — CID 158893452

IUPAC4-(8-anilinoimidazo[1,2-a]pyrazin-6-yl)-N-(2-hydroxyethyl)benzamide;3-[8-(cyclopropylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;4-[8-(cyclopropylmethylamino)imidazo[1,2-a]pyrazin-6-yl]-2-methoxyphenol;3-[8-(ethylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;N-phenyl-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine
SMILESCCNc1nc(-c2cccc(O)c2)cn2ccnc12.COc1cc(-c2cn3ccnc3c(NCC3CC3)n2)ccc1O.O=C(NCCO)c1ccc(-c2cn3ccnc3c(Nc3ccccc3)n2)cc1.Oc1cccc(-c2cn3ccnc3c(NC3CC3)n2)c1.c1ccc(Nc2nc(-c3cccnc3)cn3ccnc23)cc1
InChIInChI=1S/C21H19N5O2.C17H13N5.C17H18N4O2.C15H14N4O.C14H14N4O/c27-13-11-23-21(28)16-8-6-15(7-9-16)18-14-26-12-10-22-20(26)19(25-18)24-17-4-2-1-3-5-17;1-2-6-14(7-3-1)20-16-17-19-9-10-22(17)12-15(21-16)13-5-4-8-18-11-13;1-23-15-8-12(4-5-14(15)22)13-10-21-7-6-18-17(21)16(20-13)19-9-11-2-3-11;20-12-3-1-2-10(8-12)13-9-19-7-6-16-15(19)14(18-13)17-11-4-5-11;1-2-15-13-14-16-6-7-18(14)9-12(17-13)10-4-3-5-11(19)8-10/h1-10,12,14,27H,11,13H2,(H,23,28)(H,24,25);1-12H,(H,20,21);4-8,10-11,22H,2-3,9H2,1H3,(H,19,20);1-3,6-9,11,20H,4-5H2,(H,17,18);3-9,19H,2H2,1H3,(H,15,17)
InChIKeyJENLPUJVAPVQRO-UHFFFAOYSA-N
MW1491.70 g/mol
LogP14.54
Rot. Bonds20

About 4-(8-anilinoimidazo[1,2-a]pyrazin-6-yl)-N-(2-hydroxyethyl)benzamide;3-[8-(cyclopropylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;4-[8-(cyclopropylmethylamino)imidazo[1,2-a]pyrazin-6-yl]-2-methoxyphenol;3-[8-(ethylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;N-phenyl-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine

4-(8-anilinoimidazo[1,2-a]pyrazin-6-yl)-N-(2-hydroxyethyl)benzamide;3-[8-(cyclopropylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;4-[8-(cyclopropylmethylamino)imidazo[1,2-a]pyrazin-6-yl]-2-methoxyphenol;3-[8-(ethylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;N-phenyl-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine (PubChem CID 158893452) has the molecular formula C84H78N22O6 and a molecular weight of 1491.70 g/mol. Its IUPAC name is 4-(8-anilinoimidazo[1,2-a]pyrazin-6-yl)-N-(2-hydroxyethyl)benzamide;3-[8-(cyclopropylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;4-[8-(cyclopropylmethylamino)imidazo[1,2-a]pyrazin-6-yl]-2-methoxyphenol;3-[8-(ethylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;N-phenyl-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine.

Molecular Properties

Compound Name4-(8-anilinoimidazo[1,2-a]pyrazin-6-yl)-N-(2-hydroxyethyl)benzamide;3-[8-(cyclopropylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;4-[8-(cyclopropylmethylamino)imidazo[1,2-a]pyrazin-6-yl]-2-methoxyphenol;3-[8-(ethylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;N-phenyl-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine
PubChem CID158893452
Molecular FormulaC84H78N22O6
Molecular Weight1491.70 g/mol
Exact Mass1490.65
IUPAC Name4-(8-anilinoimidazo[1,2-a]pyrazin-6-yl)-N-(2-hydroxyethyl)benzamide;3-[8-(cyclopropylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;4-[8-(cyclopropylmethylamino)imidazo[1,2-a]pyrazin-6-yl]-2-methoxyphenol;3-[8-(ethylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;N-phenyl-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine
SMILESCCNc1nc(-c2cccc(O)c2)cn2ccnc12.COc1cc(-c2cn3ccnc3c(NCC3CC3)n2)ccc1O.O=C(NCCO)c1ccc(-c2cn3ccnc3c(Nc3ccccc3)n2)cc1.Oc1cccc(-c2cn3ccnc3c(NC3CC3)n2)c1.c1ccc(Nc2nc(-c3cccnc3)cn3ccnc23)cc1
InChIInChI=1S/C21H19N5O2.C17H13N5.C17H18N4O2.C15H14N4O.C14H14N4O/c27-13-11-23-21(28)16-8-6-15(7-9-16)18-14-26-12-10-22-20(26)19(25-18)24-17-4-2-1-3-5-17;1-2-6-14(7-3-1)20-16-17-19-9-10-22(17)12-15(21-16)13-5-4-8-18-11-13;1-23-15-8-12(4-5-14(15)22)13-10-21-7-6-18-17(21)16(20-13)19-9-11-2-3-11;20-12-3-1-2-10(8-12)13-9-19-7-6-16-15(19)14(18-13)17-11-4-5-11;1-2-15-13-14-16-6-7-18(14)9-12(17-13)10-4-3-5-11(19)8-10/h1-10,12,14,27H,11,13H2,(H,23,28)(H,24,25);1-12H,(H,20,21);4-8,10-11,22H,2-3,9H2,1H3,(H,19,20);1-3,6-9,11,20H,4-5H2,(H,17,18);3-9,19H,2H2,1H3,(H,15,17)
InChIKeyJENLPUJVAPVQRO-UHFFFAOYSA-N
XLogP14.54
TPSA343.24 Ų
H-Bond Donors10
H-Bond Acceptors27
Rotatable Bonds20
Heavy Atoms112
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001491.70
LogP ≤ 514.54
H-Bond Donors ≤ 510
H-Bond Acceptors ≤ 1027

Analyze 4-(8-anilinoimidazo[1,2-a]pyrazin-6-yl)-N-(2-hydroxyethyl)benzamide;3-[8-(cyclopropylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;4-[8-(cyclopropylmethylamino)imidazo[1,2-a]pyrazin-6-yl]-2-methoxyphenol;3-[8-(ethylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;N-phenyl-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine with MolForge

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Related Compounds

N-[2-tert-butyl-1-(2-hydroxyethyl)pyrrolo[2,3-c]pyridin-5-yl]-1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carboxamide;N-(2-tert-butyl-1H-pyrrolo[2,3-b]pyridin-5-yl)-1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carboxamide;N-(2-tert-butyl-1H-pyrrolo[3,2-b]pyridin-5-yl)-1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carboxamide;N-(2-tert-butyl-1H-pyrrolo[2,3-c]pyridin-5-yl)-1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carboxamide;N-(2-cyclobutyl-1H-pyrrolo[2,3-c]pyridin-5-yl)-1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carboxamide;1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[2-(1-methylcyclopropyl)-1H-pyrrolo[2,3-c]pyridin-5-yl]cyclopropane-1-carboxamide;molecular hydrogen
CID 157973001
4-(8-anilinoimidazo[1,2-a]pyrazin-6-yl)-N-(2-hydroxyethyl)benzamide;N-phenyl-6-[3-(trifluoromethoxy)phenyl]imidazo[1,2-a]pyrazin-8-amine;N-phenyl-6-(3,4,5-trimethoxyphenyl)imidazo[1,2-a]pyrazin-8-amine
CID 158119016
2-amino-N-[(2S,3R,5R)-5-(7-aminoimidazo[4,5-b]pyridin-3-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-hydroxyphenyl)propanamide;N-[(2S,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-methoxybenzamide;N-[(2S,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]pyridine-3-carboxamide
CID 91007562
2-amino-N-[(2S,3R,5R)-5-(7-aminoimidazo[4,5-b]pyridin-3-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-hydroxyphenyl)propanamide;N-[(2S,3R,5R)-5-(7-aminoimidazo[4,5-b]pyridin-3-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-methoxybenzamide;N-[(2S,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]pyridine-3-carboxamide
CID 91264882
4-[6-(2-aminopyrimidin-5-yl)-8-(diethylamino)-2-morpholin-4-ylpurin-9-yl]-N-methylbutanamide;1-[4-[[[6-(2-aminopyrimidin-5-yl)-2-morpholin-4-yl-9-propan-2-ylpurin-8-yl]amino]methyl]phenyl]-2-hydroxyethanone;4-[9-ethyl-8-[[[4-[(1E)-3-(hydroxyamino)buta-1,3-dienyl]phenyl]methyl-methylamino]methyl]-6-morpholin-4-ylpurin-2-yl]benzamide;N-hydroxy-7-[4-(6-morpholin-4-yl-9-propan-2-ylpurin-2-yl)phenoxy]heptanamide
CID 157073860
4-[3-[(2S)-1-but-2-ynoylpiperidin-2-yl]-8-methylimidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide;methane;1-[(2S)-2-[8-methyl-1-[3-[(3-methylphenyl)methoxy]phenyl]imidazo[1,5-a]pyrazin-3-yl]piperidin-1-yl]but-2-yn-1-one;4-[8-methyl-3-[(2S)-1-prop-2-enoylpiperidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide;4-[5-methyl-3-[(2S)-1-prop-2-enoylpyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide
CID 157077282
2-cyclopentyl-7-[3-(3-hydroxyphenyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(pyridin-2-ylmethyl)heptanamide;2-cyclopentyl-7-[3-(4-hydroxyphenyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(pyridin-2-ylmethyl)heptanamide;2-cyclopentyl-7-[3-[3-(2-methoxyethoxy)phenyl]pyrrolo[2,3-b]pyridin-1-yl]-N-(pyridin-2-ylmethyl)heptanamide;2-cyclopentyl-7-[3-[4-(2-methoxyethoxy)phenyl]pyrrolo[2,3-b]pyridin-1-yl]-N-(pyridin-2-ylmethyl)heptanamide;bis(2-methoxyethanol)
CID 157083580
2-[N-ethyl-4-[[6-[2-(hydroxymethyl)phenyl]imidazo[1,2-a]pyrazin-8-yl]amino]anilino]ethanol;6-(2-fluorophenyl)-N-(pyridin-2-ylmethyl)imidazo[1,2-a]pyrazin-8-amine;N-[4-[[6-(4-hydroxyphenyl)imidazo[1,2-a]pyrazin-8-yl]amino]phenyl]acetamide;N-(pyridin-2-ylmethyl)-6-(3,4,5-trimethoxyphenyl)imidazo[1,2-a]pyrazin-8-amine
CID 157124425
[3-[cyclohexylmethoxy-(3-methylphenyl)methyl]-2-methylimidazo[1,2-a]pyridin-6-yl]-piperidin-1-ylmethanone;[3-[3-(cyclohexylmethoxy)phenyl]-2-methylimidazo[1,2-a]pyridin-6-yl]-piperidin-1-ylmethanone;cyclohexyl-[4-[3-[2-methyl-6-(piperidine-1-carbonyl)imidazo[1,2-a]pyridin-3-yl]phenyl]piperazin-1-yl]methanone;[3-[hydroxy-(3-methylphenyl)methyl]-2-methylimidazo[1,2-a]pyridin-6-yl]-piperidin-1-ylmethanone;[2-methyl-3-(3-methylbenzoyl)imidazo[1,2-a]pyridin-6-yl]-piperidin-1-ylmethanone;[2-methyl-3-[1-(3-methylphenyl)ethyl]imidazo[1,2-a]pyridin-6-yl]-piperidin-1-ylmethanone;N-(2-methyl-3-phenylimidazo[1,2-a]pyridin-6-yl)oxane-4-carboxamide
CID 157169588
N-(cyclopropylmethyl)-4-[5-(2-phenoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]benzamide;N-cyclopropyl-4-[5-(2-phenoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]benzamide;N-(2-hydroxyethyl)-4-[5-(2-phenoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]benzamide;N-(2-methoxyethyl)-4-[5-(2-phenoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]benzamide;4-[5-(2-phenoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-N-pyridin-3-ylbenzamide
CID 157338888
N-methyl-2-[3-(2-morpholin-4-yl-9-propan-2-ylpurin-6-yl)phenoxy]acetamide;N-methyl-7-[4-(2-morpholin-4-yl-9-propan-2-ylpurin-6-yl)phenoxy]heptanamide;N-methyl-4-[[3-(2-morpholin-4-yl-9-propan-2-ylpurin-6-yl)phenoxy]methyl]benzamide;N-methyl-5-[[4-(2-morpholin-4-yl-9-propan-2-ylpurin-6-yl)phenyl]methoxy]pentanamide
CID 157349022
ethyl 4-[2-methyl-6-(piperidine-1-carbonyl)imidazo[1,2-a]pyridin-3-yl]benzoate;[3-(3-hydroxyphenyl)-2-methylimidazo[1,2-a]pyridin-6-yl]-piperidin-1-ylmethanone;[3-(4-methoxyphenyl)-2-methylimidazo[1,2-a]pyridin-6-yl]-piperidin-1-ylmethanone;[2-methyl-3-(3-methylphenyl)imidazo[1,2-a]pyridin-6-yl]-piperidin-1-ylmethanone;[2-methyl-3-(4-methylphenyl)imidazo[1,2-a]pyridin-6-yl]-piperidin-1-ylmethanone;N-[3-[2-methyl-6-(piperidine-1-carbonyl)imidazo[1,2-a]pyridin-3-yl]phenyl]acetamide;[2-methyl-3-(3-propan-2-yloxyphenyl)imidazo[1,2-a]pyridin-6-yl]-piperidin-1-ylmethanone
CID 157368765

Frequently Asked Questions

What is the IUPAC name of 4-(8-anilinoimidazo[1,2-a]pyrazin-6-yl)-N-(2-hydroxyethyl)benzamide;3-[8-(cyclopropylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;4-[8-(cyclopropylmethylamino)imidazo[1,2-a]pyrazin-6-yl]-2-methoxyphenol;3-[8-(ethylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;N-phenyl-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine?
The IUPAC name of 4-(8-anilinoimidazo[1,2-a]pyrazin-6-yl)-N-(2-hydroxyethyl)benzamide;3-[8-(cyclopropylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;4-[8-(cyclopropylmethylamino)imidazo[1,2-a]pyrazin-6-yl]-2-methoxyphenol;3-[8-(ethylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;N-phenyl-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine (CID 158893452) is 4-(8-anilinoimidazo[1,2-a]pyrazin-6-yl)-N-(2-hydroxyethyl)benzamide;3-[8-(cyclopropylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;4-[8-(cyclopropylmethylamino)imidazo[1,2-a]pyrazin-6-yl]-2-methoxyphenol;3-[8-(ethylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;N-phenyl-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine.
What is the SMILES notation for 4-(8-anilinoimidazo[1,2-a]pyrazin-6-yl)-N-(2-hydroxyethyl)benzamide;3-[8-(cyclopropylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;4-[8-(cyclopropylmethylamino)imidazo[1,2-a]pyrazin-6-yl]-2-methoxyphenol;3-[8-(ethylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;N-phenyl-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine?
The canonical SMILES for 4-(8-anilinoimidazo[1,2-a]pyrazin-6-yl)-N-(2-hydroxyethyl)benzamide;3-[8-(cyclopropylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;4-[8-(cyclopropylmethylamino)imidazo[1,2-a]pyrazin-6-yl]-2-methoxyphenol;3-[8-(ethylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;N-phenyl-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine is CCNc1nc(-c2cccc(O)c2)cn2ccnc12.COc1cc(-c2cn3ccnc3c(NCC3CC3)n2)ccc1O.O=C(NCCO)c1ccc(-c2cn3ccnc3c(Nc3ccccc3)n2)cc1.Oc1cccc(-c2cn3ccnc3c(NC3CC3)n2)c1.c1ccc(Nc2nc(-c3cccnc3)cn3ccnc23)cc1.
What is the InChIKey of 4-(8-anilinoimidazo[1,2-a]pyrazin-6-yl)-N-(2-hydroxyethyl)benzamide;3-[8-(cyclopropylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;4-[8-(cyclopropylmethylamino)imidazo[1,2-a]pyrazin-6-yl]-2-methoxyphenol;3-[8-(ethylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;N-phenyl-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine?
The InChIKey is JENLPUJVAPVQRO-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H19N5O2.C17H13N5.C17H18N4O2.C15H14N4O.C14H14N4O/c27-13-11-23-21(28)16-8-6-15(7-9-16)18-14-26-12-10-22-20(26)19(25-18)24-17-4-2-1-3-5-17;1-2-6-14(7-3-1)20-16-17-19-9-10-22(17)12-15(21-16)13-5-4-8-18-11-13;1-23-15-8-12(4-5-14(15)22)13-10-21-7-6-18-17(21)16(20-13)19-9-11-2-3-11;20-12-3-1-2-10(8-12)13-9-19-7-6-16-15(19)14(18-13)17-11-4-5-11;1-2-15-13-14-16-6-7-18(14)9-12(17-13)10-4-3-5-11(19)8-10/h1-10,12,14,27H,11,13H2,(H,23,28)(H,24,25);1-12H,(H,20,21);4-8,10-11,22H,2-3,9H2,1H3,(H,19,20);1-3,6-9,11,20H,4-5H2,(H,17,18);3-9,19H,2H2,1H3,(H,15,17).
What are the key properties of 4-(8-anilinoimidazo[1,2-a]pyrazin-6-yl)-N-(2-hydroxyethyl)benzamide;3-[8-(cyclopropylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;4-[8-(cyclopropylmethylamino)imidazo[1,2-a]pyrazin-6-yl]-2-methoxyphenol;3-[8-(ethylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;N-phenyl-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine?
4-(8-anilinoimidazo[1,2-a]pyrazin-6-yl)-N-(2-hydroxyethyl)benzamide;3-[8-(cyclopropylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;4-[8-(cyclopropylmethylamino)imidazo[1,2-a]pyrazin-6-yl]-2-methoxyphenol;3-[8-(ethylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;N-phenyl-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine has a molecular weight of 1491.70 g/mol, XLogP of 14.54, 20 rotatable bonds, 10 hydrogen bond donors, and 27 hydrogen bond acceptors.
Where does this data come from?
All data for 4-(8-anilinoimidazo[1,2-a]pyrazin-6-yl)-N-(2-hydroxyethyl)benzamide;3-[8-(cyclopropylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;4-[8-(cyclopropylmethylamino)imidazo[1,2-a]pyrazin-6-yl]-2-methoxyphenol;3-[8-(ethylamino)imidazo[1,2-a]pyrazin-6-yl]phenol;N-phenyl-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine is sourced from PubChem (CID 158893452), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).