8-(2-ethoxy-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methoxy-5-methyl-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-[6-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-amine

C68H61F6N15O5 — CID 158906370

About 8-(2-ethoxy-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methoxy-5-methyl-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-[6-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-amine

8-(2-ethoxy-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methoxy-5-methyl-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-[6-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-amine (PubChem CID 158906370) has the molecular formula C68H61F6N15O5 and a molecular weight of 1282.32 g/mol. Its IUPAC name is 8-(2-ethoxy-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methoxy-5-methyl-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-[6-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-amine.

Molecular Properties

• Compound Name: 8-(2-ethoxy-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methoxy-5-methyl-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-[6-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-amine
• PubChem CID: 158906370
• Molecular Formula: C68H61F6N15O5
• Molecular Weight: 1282.32 g/mol
• Exact Mass: 1281.49
• IUPAC Name: 8-(2-ethoxy-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methoxy-5-methyl-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-[6-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-amine
• SMILES: CCOc1ncccc1-c1cnc(NCc2c(F)ccc3c2CCO3)n2cc(C)nc12.COc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cc(C)nc23)c(C)cn1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3ccc(C(F)(F)F)nc3)c2n1
• InChI: InChI=1S/2C23H22FN5O2.C22H17F4N5O/c1-13-9-25-21(30-3)8-16(13)18-11-27-23(29-12-14(2)28-22(18)29)26-10-17-15-6-7-31-20(15)5-4-19(17)24;1-3-30-22-16(5-4-9-25-22)18-12-27-23(29-13-14(2)28-21(18)29)26-11-17-15-8-10-31-20(15)7-6-19(17)24;1-12-11-31-20(30-12)15(13-2-5-19(27-8-13)22(24,25)26)9-28-21(31)29-10-16-14-6-7-32-18(14)4-3-17(16)23/h4-5,8-9,11-12H,6-7,10H2,1-3H3,(H,26,27);4-7,9,12-13H,3,8,10-11H2,1-2H3,(H,26,27);2-5,8-9,11H,6-7,10H2,1H3,(H,28,29)
• InChIKey: JGCBVJPVAKQETI-UHFFFAOYSA-N
• XLogP: 13.09
• TPSA: 211.48 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 20
• Rotatable Bonds: 15
• Heavy Atoms: 94
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1282.32
LogP ≤ 5	13.09
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	20

Frequently Asked Questions

What is the IUPAC name of 8-(2-ethoxy-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methoxy-5-methyl-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-[6-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-amine?

The IUPAC name of 8-(2-ethoxy-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methoxy-5-methyl-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-[6-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-amine (CID 158906370) is 8-(2-ethoxy-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methoxy-5-methyl-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-[6-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-amine.

What is the SMILES notation for 8-(2-ethoxy-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methoxy-5-methyl-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-[6-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-amine?

The canonical SMILES for 8-(2-ethoxy-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methoxy-5-methyl-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-[6-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-amine is CCOc1ncccc1-c1cnc(NCc2c(F)ccc3c2CCO3)n2cc(C)nc12.COc1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cc(C)nc23)c(C)cn1.Cc1cn2c(NCc3c(F)ccc4c3CCO4)ncc(-c3ccc(C(F)(F)F)nc3)c2n1.

What is the InChIKey of 8-(2-ethoxy-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methoxy-5-methyl-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-[6-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-amine?

The InChIKey is JGCBVJPVAKQETI-UHFFFAOYSA-N. The full InChI is InChI=1S/2C23H22FN5O2.C22H17F4N5O/c1-13-9-25-21(30-3)8-16(13)18-11-27-23(29-12-14(2)28-22(18)29)26-10-17-15-6-7-31-20(15)5-4-19(17)24;1-3-30-22-16(5-4-9-25-22)18-12-27-23(29-13-14(2)28-21(18)29)26-11-17-15-8-10-31-20(15)7-6-19(17)24;1-12-11-31-20(30-12)15(13-2-5-19(27-8-13)22(24,25)26)9-28-21(31)29-10-16-14-6-7-32-18(14)4-3-17(16)23/h4-5,8-9,11-12H,6-7,10H2,1-3H3,(H,26,27);4-7,9,12-13H,3,8,10-11H2,1-2H3,(H,26,27);2-5,8-9,11H,6-7,10H2,1H3,(H,28,29).

What are the key properties of 8-(2-ethoxy-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methoxy-5-methyl-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-[6-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-amine?

8-(2-ethoxy-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methoxy-5-methyl-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-[6-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-amine has a molecular weight of 1282.32 g/mol, XLogP of 13.09, 15 rotatable bonds, 3 hydrogen bond donors, and 20 hydrogen bond acceptors.

Where does this data come from?

All data for 8-(2-ethoxy-3-pyridinyl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methoxy-5-methyl-4-pyridinyl)-2-methylimidazo[1,2-c]pyrimidin-5-amine;N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-2-methyl-8-[6-(trifluoromethyl)-3-pyridinyl]imidazo[1,2-c]pyrimidin-5-amine is sourced from PubChem (CID 158906370), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).