5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(4-fluorophenyl)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide

C87H71F7N18O3 — CID 158907261

About 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(4-fluorophenyl)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide

5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(4-fluorophenyl)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide (PubChem CID 158907261) has the molecular formula C87H71F7N18O3 and a molecular weight of 1549.63 g/mol. Its IUPAC name is 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(4-fluorophenyl)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide.

Molecular Properties

• Compound Name: 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(4-fluorophenyl)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide
• PubChem CID: 158907261
• Molecular Formula: C87H71F7N18O3
• Molecular Weight: 1549.63 g/mol
• Exact Mass: 1548.58
• IUPAC Name: 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(4-fluorophenyl)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide
• SMILES: O=C(Nc1ccc(-c2ccc(F)cc2)nc1)c1n[nH]c2ccc(-c3cncc(CN4CCC(F)(F)C4)c3)cc12.O=C(Nc1ccc(-c2ccc(F)cc2)nc1)c1n[nH]c2ccc(-c3cncc(CN4CCC(F)(F)CC4)c3)cc12.O=C(Nc1ccc(-c2ccc(F)cc2)nc1)c1n[nH]c2ccc(-c3cncc(N4CCCC4)c3)cc12
• InChI: InChI=1S/C30H25F3N6O.C29H23F3N6O.C28H23FN6O/c31-23-4-1-20(2-5-23)26-8-6-24(17-35-26)36-29(40)28-25-14-21(3-7-27(25)37-38-28)22-13-19(15-34-16-22)18-39-11-9-30(32,33)10-12-39;30-22-4-1-19(2-5-22)25-8-6-23(15-34-25)35-28(39)27-24-12-20(3-7-26(24)36-37-27)21-11-18(13-33-14-21)16-38-10-9-29(31,32)17-38;29-21-6-3-18(4-7-21)25-10-8-22(16-31-25)32-28(36)27-24-14-19(5-9-26(24)33-34-27)20-13-23(17-30-15-20)35-11-1-2-12-35/h1-8,13-17H,9-12,18H2,(H,36,40)(H,37,38);1-8,11-15H,9-10,16-17H2,(H,35,39)(H,36,37);3-10,13-17H,1-2,11-12H2,(H,32,36)(H,33,34)
• InChIKey: JGEVFBYSDADYOS-UHFFFAOYSA-N
• XLogP: 17.91
• TPSA: 260.40 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 15
• Rotatable Bonds: 17
• Heavy Atoms: 115
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1549.63
LogP ≤ 5	17.91
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	15

Frequently Asked Questions

What is the IUPAC name of 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(4-fluorophenyl)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide?

The IUPAC name of 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(4-fluorophenyl)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide (CID 158907261) is 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(4-fluorophenyl)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide.

What is the SMILES notation for 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(4-fluorophenyl)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide?

The canonical SMILES for 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(4-fluorophenyl)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide is O=C(Nc1ccc(-c2ccc(F)cc2)nc1)c1n[nH]c2ccc(-c3cncc(CN4CCC(F)(F)C4)c3)cc12.O=C(Nc1ccc(-c2ccc(F)cc2)nc1)c1n[nH]c2ccc(-c3cncc(CN4CCC(F)(F)CC4)c3)cc12.O=C(Nc1ccc(-c2ccc(F)cc2)nc1)c1n[nH]c2ccc(-c3cncc(N4CCCC4)c3)cc12.

What is the InChIKey of 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(4-fluorophenyl)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide?

The InChIKey is JGEVFBYSDADYOS-UHFFFAOYSA-N. The full InChI is InChI=1S/C30H25F3N6O.C29H23F3N6O.C28H23FN6O/c31-23-4-1-20(2-5-23)26-8-6-24(17-35-26)36-29(40)28-25-14-21(3-7-27(25)37-38-28)22-13-19(15-34-16-22)18-39-11-9-30(32,33)10-12-39;30-22-4-1-19(2-5-22)25-8-6-23(15-34-25)35-28(39)27-24-12-20(3-7-26(24)36-37-27)21-11-18(13-33-14-21)16-38-10-9-29(31,32)17-38;29-21-6-3-18(4-7-21)25-10-8-22(16-31-25)32-28(36)27-24-14-19(5-9-26(24)33-34-27)20-13-23(17-30-15-20)35-11-1-2-12-35/h1-8,13-17H,9-12,18H2,(H,36,40)(H,37,38);1-8,11-15H,9-10,16-17H2,(H,35,39)(H,36,37);3-10,13-17H,1-2,11-12H2,(H,32,36)(H,33,34).

What are the key properties of 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(4-fluorophenyl)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide?

5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(4-fluorophenyl)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide has a molecular weight of 1549.63 g/mol, XLogP of 17.91, 17 rotatable bonds, 6 hydrogen bond donors, and 15 hydrogen bond acceptors.

Where does this data come from?

All data for 5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-fluorophenyl)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(4-fluorophenyl)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide is sourced from PubChem (CID 158907261), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).