N-[3,3-bis(4-fluorophenyl)propyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-(naphthalen-1-ylmethyl)-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-phenylphenyl)ethyl]-4-(pyridin-2-ylmethyl)piperidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]piperidine-1-carboxamide

C162H180ClF9N32O17 — CID 158926093

IUPACN-[3,3-bis(4-fluorophenyl)propyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-(naphthalen-1-ylmethyl)-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-phenylphenyl)ethyl]-4-(pyridin-2-ylmethyl)piperidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]piperidine-1-carboxamide
SMILESCOc1ccc(CCNC(=O)N2CCC(Oc3ncccn3)CC2)cc1.C[C@H](CNC(=O)N1CCC(Oc2ncccn2)CC1)c1ccccc1.O=C(NCCC(c1ccc(F)cc1)c1ccc(F)cc1)N1CCC(Oc2ncccn2)CC1.O=C(NCCc1ccc(-c2ccccc2)cc1)N1CCC(Cc2ccccn2)CC1.O=C(NCc1ccc(C(F)(F)F)nc1)N1CCC(Oc2ncccn2)CC1.O=C(NCc1ccc(F)cc1Cl)N1CCC(Oc2ncccn2)CC1.O=C(NCc1cccc(OC(F)(F)F)c1)N1CCC(Oc2ncccn2)CC1.O=C(NCc1cccc2ccccc12)N1CCC(Oc2ncccn2)CC1
InChIInChI=1S/C26H29N3O.C25H26F2N4O2.C21H22N4O2.C19H24N4O3.C19H24N4O2.C18H19F3N4O3.C17H18ClFN4O2.C17H18F3N5O2/c30-26(29-18-14-22(15-19-29)20-25-8-4-5-16-27-25)28-17-13-21-9-11-24(12-10-21)23-6-2-1-3-7-23;26-20-6-2-18(3-7-20)23(19-4-8-21(27)9-5-19)10-15-30-25(32)31-16-11-22(12-17-31)33-24-28-13-1-14-29-24;26-21(24-15-17-7-3-6-16-5-1-2-8-19(16)17)25-13-9-18(10-14-25)27-20-22-11-4-12-23-20;1-25-16-5-3-15(4-6-16)7-12-22-19(24)23-13-8-17(9-14-23)26-18-20-10-2-11-21-18;1-15(16-6-3-2-4-7-16)14-22-19(24)23-12-8-17(9-13-23)25-18-20-10-5-11-21-18;19-18(20,21)28-15-4-1-3-13(11-15)12-24-17(26)25-9-5-14(6-10-25)27-16-22-7-2-8-23-16;18-15-10-13(19)3-2-12(15)11-22-17(24)23-8-4-14(5-9-23)25-16-20-6-1-7-21-16;18-17(19,20)14-3-2-12(10-23-14)11-24-16(26)25-8-4-13(5-9-25)27-15-21-6-1-7-22-15/h1-12,16,22H,13-15,17-20H2,(H,28,30);1-9,13-14,22-23H,10-12,15-17H2,(H,30,32);1-8,11-12,18H,9-10,13-15H2,(H,24,26);2-6,10-11,17H,7-9,12-14H2,1H3,(H,22,24);2-7,10-11,15,17H,8-9,12-14H2,1H3,(H,22,24);1-4,7-8,11,14H,5-6,9-10,12H2,(H,24,26);1-3,6-7,10,14H,4-5,8-9,11H2,(H,22,24);1-3,6-7,10,13H,4-5,8-9,11H2,(H,24,26)/t;;;;15-;;;/m....1.../s1
InChIKeyJILODFYAYINEQD-RJGLIUARSA-N
MW3053.86 g/mol
LogP26.78
Rot. Bonds41

About N-[3,3-bis(4-fluorophenyl)propyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-(naphthalen-1-ylmethyl)-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-phenylphenyl)ethyl]-4-(pyridin-2-ylmethyl)piperidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]piperidine-1-carboxamide

N-[3,3-bis(4-fluorophenyl)propyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-(naphthalen-1-ylmethyl)-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-phenylphenyl)ethyl]-4-(pyridin-2-ylmethyl)piperidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]piperidine-1-carboxamide (PubChem CID 158926093) has the molecular formula C162H180ClF9N32O17 and a molecular weight of 3053.86 g/mol. Its IUPAC name is N-[3,3-bis(4-fluorophenyl)propyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-(naphthalen-1-ylmethyl)-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-phenylphenyl)ethyl]-4-(pyridin-2-ylmethyl)piperidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]piperidine-1-carboxamide.

Molecular Properties

Compound NameN-[3,3-bis(4-fluorophenyl)propyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-(naphthalen-1-ylmethyl)-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-phenylphenyl)ethyl]-4-(pyridin-2-ylmethyl)piperidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]piperidine-1-carboxamide
PubChem CID158926093
Molecular FormulaC162H180ClF9N32O17
Molecular Weight3053.86 g/mol
Exact Mass3051.37
IUPAC NameN-[3,3-bis(4-fluorophenyl)propyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-(naphthalen-1-ylmethyl)-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-phenylphenyl)ethyl]-4-(pyridin-2-ylmethyl)piperidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]piperidine-1-carboxamide
SMILESCOc1ccc(CCNC(=O)N2CCC(Oc3ncccn3)CC2)cc1.C[C@H](CNC(=O)N1CCC(Oc2ncccn2)CC1)c1ccccc1.O=C(NCCC(c1ccc(F)cc1)c1ccc(F)cc1)N1CCC(Oc2ncccn2)CC1.O=C(NCCc1ccc(-c2ccccc2)cc1)N1CCC(Cc2ccccn2)CC1.O=C(NCc1ccc(C(F)(F)F)nc1)N1CCC(Oc2ncccn2)CC1.O=C(NCc1ccc(F)cc1Cl)N1CCC(Oc2ncccn2)CC1.O=C(NCc1cccc(OC(F)(F)F)c1)N1CCC(Oc2ncccn2)CC1.O=C(NCc1cccc2ccccc12)N1CCC(Oc2ncccn2)CC1
InChIInChI=1S/C26H29N3O.C25H26F2N4O2.C21H22N4O2.C19H24N4O3.C19H24N4O2.C18H19F3N4O3.C17H18ClFN4O2.C17H18F3N5O2/c30-26(29-18-14-22(15-19-29)20-25-8-4-5-16-27-25)28-17-13-21-9-11-24(12-10-21)23-6-2-1-3-7-23;26-20-6-2-18(3-7-20)23(19-4-8-21(27)9-5-19)10-15-30-25(32)31-16-11-22(12-17-31)33-24-28-13-1-14-29-24;26-21(24-15-17-7-3-6-16-5-1-2-8-19(16)17)25-13-9-18(10-14-25)27-20-22-11-4-12-23-20;1-25-16-5-3-15(4-6-16)7-12-22-19(24)23-13-8-17(9-14-23)26-18-20-10-2-11-21-18;1-15(16-6-3-2-4-7-16)14-22-19(24)23-12-8-17(9-13-23)25-18-20-10-5-11-21-18;19-18(20,21)28-15-4-1-3-13(11-15)12-24-17(26)25-9-5-14(6-10-25)27-16-22-7-2-8-23-16;18-15-10-13(19)3-2-12(15)11-22-17(24)23-8-4-14(5-9-23)25-16-20-6-1-7-21-16;18-17(19,20)14-3-2-12(10-23-14)11-24-16(26)25-8-4-13(5-9-25)27-15-21-6-1-7-22-15/h1-12,16,22H,13-15,17-20H2,(H,28,30);1-9,13-14,22-23H,10-12,15-17H2,(H,30,32);1-8,11-12,18H,9-10,13-15H2,(H,24,26);2-6,10-11,17H,7-9,12-14H2,1H3,(H,22,24);2-7,10-11,15,17H,8-9,12-14H2,1H3,(H,22,24);1-4,7-8,11,14H,5-6,9-10,12H2,(H,24,26);1-3,6-7,10,14H,4-5,8-9,11H2,(H,22,24);1-3,6-7,10,13H,4-5,8-9,11H2,(H,24,26)/t;;;;15-;;;/m....1.../s1
InChIKeyJILODFYAYINEQD-RJGLIUARSA-N
XLogP26.78
TPSA548.03 Ų
H-Bond Donors8
H-Bond Acceptors33
Rotatable Bonds41
Heavy Atoms221
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003053.86
LogP ≤ 526.78
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1033

Analyze N-[3,3-bis(4-fluorophenyl)propyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-(naphthalen-1-ylmethyl)-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-phenylphenyl)ethyl]-4-(pyridin-2-ylmethyl)piperidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]piperidine-1-carboxamide with MolForge

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Related Compounds

2,2,2-trifluoro-N-((1-(4-(6-methoxynaphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methyl)acetamide (4-(4-(6-Methoxynaphthalen-2-yl)pyrimidin-2-yl)cyclohexyl)methanamine
CID 86627989
2,2,2-trifluoro-N-((1-(4-(6-hydroxynaphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methyl)acetamide 2,2,2-trifluoro-N-((1-(4-(6-methoxynaphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methyl)acetamide
CID 136346729
N-[[1-[4-(6-ethoxynaphthalen-2-yl)pyrimidin-2-yl]piperidin-4-yl]methyl]-2,2,2-trifluoroacetamide;2,2,2-trifluoro-N-[[1-[4-(6-hydroxynaphthalen-2-yl)pyrimidin-2-yl]piperidin-4-yl]methyl]acetamide
CID 136363978
1-[1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-(piperidin-3-ylamino)pyrimidin-4-yl]pyridin-2-one;1-[1-(1H-inden-5-yl)ethyl]-4-[2-(oxan-4-ylamino)pyrimidin-4-yl]pyridin-2-one;1-(1H-inden-5-ylmethyl)-4-[2-(oxan-4-ylamino)pyrimidin-4-yl]pyridin-2-one;1-[2-(4-methoxyphenyl)ethyl]-4-[2-(oxan-4-ylamino)pyrimidin-4-yl]pyridin-2-one;1-[2-(3-methylphenyl)ethyl]-4-[2-(oxan-4-ylamino)pyrimidin-4-yl]pyridin-2-one;4-[2-(oxan-4-ylamino)pyrimidin-4-yl]-1-[2-[3-(trifluoromethyl)phenyl]ethyl]pyridin-2-one;4-[2-(oxan-4-ylamino)pyrimidin-4-yl]-1-[2-[4-(trifluoromethyl)phenyl]ethyl]pyridin-2-one
CID 157186610
N-[3,3-bis(4-fluorophenyl)propyl]-3-pyridin-4-ylpyrrolidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-3-pyridin-4-ylpyrrolidine-1-carboxamide;N-[(2,4-dichlorophenyl)methyl]-3-pyridin-4-ylpyrrolidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-4-(pyridin-3-ylmethyl)piperidine-1-carboxamide;N-(naphthalen-1-ylmethyl)-3-pyridin-4-ylpyrrolidine-1-carboxamide;N-[2-(4-phenylphenyl)ethyl]-3-pyridin-4-ylpyrrolidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-4-(pyridin-3-ylmethyl)piperidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-3-pyridin-4-ylpyrrolidine-1-carboxamide;4-(pyridin-3-ylmethyl)-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidine-1-carboxamide;4-(pyridin-3-ylmethyl)-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]piperidine-1-carboxamide
CID 157364598
bis(1-chloro-2-methyl-4-propan-2-ylbenzene);4-chloro-2-methyl-1-propan-2-ylbenzene;2-chloro-1-propan-2-yl-4-(trifluoromethyl)benzene;4-chloro-1-propan-2-yl-2-(trifluoromethyl)benzene;cumene;2,4-dichloro-1-propan-2-ylbenzene;1,2-difluoro-4-propan-2-ylbenzene;2-fluoro-1-methoxy-4-propan-2-ylbenzene;1-fluoro-2-methyl-4-propan-2-ylbenzene;4-fluoro-2-methyl-1-propan-2-ylbenzene;4-methoxy-2-methyl-1-propan-2-ylbenzene;1-methoxy-4-propan-2-ylbenzene;1-methyl-2-propan-2-ylbenzene;bis(1-methyl-4-propan-2-ylbenzene);2-methyl-5-propan-2-ylpyridine;bis(2-methyl-1-propan-2-yl-4-(trifluoromethyl)benzene);2-propan-2-ylpyrazine;2-propan-2-ylpyridine;3-propan-2-ylpyridine;4-propan-2-ylpyridine;2-propan-2-ylpyrimidine;5-propan-2-ylpyrimidine;4-propan-2-yl-3H-pyrrole;1-propan-2-yl-4-(trifluoromethyl)benzene;5-propan-2-yl-2-(trifluoromethyl)pyridine
CID 157653688
N-[3,3-bis(4-fluorophenyl)propyl]-4-(pyridin-2-ylmethyl)piperidine-1-carboxamide;N-[(2,4-dichlorophenyl)methyl]-4-pyridin-2-yloxypiperidine-1-carboxamide;bis(N-[2-(4-methoxyphenyl)ethyl]-4-pyridin-2-yloxypiperidine-1-carboxamide);N-[2-(4-phenylphenyl)ethyl]-4-(pyridin-2-ylmethyl)piperidine-1-carboxamide;N-[2-(4-phenylphenyl)ethyl]-4-pyridin-2-yloxypiperidine-1-carboxamide;4-pyridin-2-yloxy-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidine-1-carboxamide;4-pyridin-2-yloxy-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]piperidine-1-carboxamide
CID 157702089
N-[3,3-bis(4-fluorophenyl)propyl]-4-(pyridin-3-ylmethyl)piperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-(pyridin-3-ylmethyl)piperidine-1-carboxamide;N-[(2,4-dichlorophenyl)methyl]-4-(pyridin-3-ylmethyl)piperidine-1-carboxamide;3-(hydroxymethyl)-N-[2-(4-methoxyphenyl)ethyl]piperidine-1-carboxamide;3-(hydroxymethyl)-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidine-1-carboxamide;3-(hydroxymethyl)-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]piperidine-1-carboxamide;N-(naphthalen-1-ylmethyl)-4-(pyridin-3-ylmethyl)piperidine-1-carboxamide;N-[2-(4-phenylphenyl)ethyl]-4-pyridin-3-yloxypiperidine-1-carboxamide
CID 157762463
N-[3,3-bis(4-fluorophenyl)propyl]-3-pyridin-3-ylpyrrolidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-3-pyridin-3-ylpyrrolidine-1-carboxamide;N-[(2,4-dichlorophenyl)methyl]-3-pyridin-3-ylpyrrolidine-1-carboxamide;4-(4-fluorophenoxy)-N-[2-(4-methoxyphenyl)ethyl]piperidine-1-carboxamide;4-(4-fluorophenoxy)-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidine-1-carboxamide;4-(4-fluorophenoxy)-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]piperidine-1-carboxamide;N-(naphthalen-1-ylmethyl)-3-pyridin-3-ylpyrrolidine-1-carboxamide;N-[2-(4-phenylphenyl)ethyl]-3-pyridin-3-ylpyrrolidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-3-pyridin-3-ylpyrrolidine-1-carboxamide;3-pyridin-3-yl-N-(pyridin-2-ylmethyl)pyrrolidine-1-carboxamide
CID 157807412
1-[1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-(piperidin-3-ylamino)pyrimidin-4-yl]pyridin-2-one;1-[2-(4-chlorophenyl)ethyl]-4-[2-(oxan-4-ylamino)pyrimidin-4-yl]pyridin-2-one;1-(1H-inden-5-ylmethyl)-4-[2-(oxan-4-ylamino)pyrimidin-4-yl]pyridin-2-one;1-[2-(3-methoxyphenyl)ethyl]-4-[2-(oxan-4-ylamino)pyrimidin-4-yl]pyridin-2-one;1-[2-(4-methylphenyl)ethyl]-4-[2-(oxan-4-ylamino)pyrimidin-4-yl]pyridin-2-one;4-[2-(oxan-4-ylamino)pyrimidin-4-yl]-1-[2-[4-(trifluoromethyl)phenyl]ethyl]pyridin-2-one
CID 157968577
tert-butylbenzene;1-tert-butyl-4-chloro-2-methylbenzene;1-tert-butyl-2,4-dichlorobenzene;1-tert-butyl-4-fluoro-2-methylbenzene;bis(1-tert-butyl-4-methylbenzene);2-tert-butylpyridine;3-tert-butylpyridine;4-tert-butylpyridine;4-tert-butyl-3H-pyrrole;2-chloro-1-propan-2-yl-4-(trifluoromethyl)benzene;4-chloro-1-propan-2-yl-2-(trifluoromethyl)benzene;cumene;4-methoxy-2-methyl-1-propan-2-ylbenzene;1-methoxy-4-propan-2-ylbenzene;1-methyl-2-propan-2-ylbenzene;2-methyl-5-propan-2-ylpyridine;2-methyl-1-propan-2-yl-4-(trifluoromethyl)benzene;2-propan-2-ylpyridine;2-propan-2-ylpyrimidine;1-propan-2-yl-4-(trifluoromethyl)benzene;5-propan-2-yl-2-(trifluoromethyl)pyridine
CID 158402779
CID 158517499
CID 158517499

Frequently Asked Questions

What is the IUPAC name of N-[3,3-bis(4-fluorophenyl)propyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-(naphthalen-1-ylmethyl)-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-phenylphenyl)ethyl]-4-(pyridin-2-ylmethyl)piperidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]piperidine-1-carboxamide?
The IUPAC name of N-[3,3-bis(4-fluorophenyl)propyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-(naphthalen-1-ylmethyl)-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-phenylphenyl)ethyl]-4-(pyridin-2-ylmethyl)piperidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]piperidine-1-carboxamide (CID 158926093) is N-[3,3-bis(4-fluorophenyl)propyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-(naphthalen-1-ylmethyl)-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-phenylphenyl)ethyl]-4-(pyridin-2-ylmethyl)piperidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]piperidine-1-carboxamide.
What is the SMILES notation for N-[3,3-bis(4-fluorophenyl)propyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-(naphthalen-1-ylmethyl)-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-phenylphenyl)ethyl]-4-(pyridin-2-ylmethyl)piperidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]piperidine-1-carboxamide?
The canonical SMILES for N-[3,3-bis(4-fluorophenyl)propyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-(naphthalen-1-ylmethyl)-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-phenylphenyl)ethyl]-4-(pyridin-2-ylmethyl)piperidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]piperidine-1-carboxamide is COc1ccc(CCNC(=O)N2CCC(Oc3ncccn3)CC2)cc1.C[C@H](CNC(=O)N1CCC(Oc2ncccn2)CC1)c1ccccc1.O=C(NCCC(c1ccc(F)cc1)c1ccc(F)cc1)N1CCC(Oc2ncccn2)CC1.O=C(NCCc1ccc(-c2ccccc2)cc1)N1CCC(Cc2ccccn2)CC1.O=C(NCc1ccc(C(F)(F)F)nc1)N1CCC(Oc2ncccn2)CC1.O=C(NCc1ccc(F)cc1Cl)N1CCC(Oc2ncccn2)CC1.O=C(NCc1cccc(OC(F)(F)F)c1)N1CCC(Oc2ncccn2)CC1.O=C(NCc1cccc2ccccc12)N1CCC(Oc2ncccn2)CC1.
What is the InChIKey of N-[3,3-bis(4-fluorophenyl)propyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-(naphthalen-1-ylmethyl)-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-phenylphenyl)ethyl]-4-(pyridin-2-ylmethyl)piperidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]piperidine-1-carboxamide?
The InChIKey is JILODFYAYINEQD-RJGLIUARSA-N. The full InChI is InChI=1S/C26H29N3O.C25H26F2N4O2.C21H22N4O2.C19H24N4O3.C19H24N4O2.C18H19F3N4O3.C17H18ClFN4O2.C17H18F3N5O2/c30-26(29-18-14-22(15-19-29)20-25-8-4-5-16-27-25)28-17-13-21-9-11-24(12-10-21)23-6-2-1-3-7-23;26-20-6-2-18(3-7-20)23(19-4-8-21(27)9-5-19)10-15-30-25(32)31-16-11-22(12-17-31)33-24-28-13-1-14-29-24;26-21(24-15-17-7-3-6-16-5-1-2-8-19(16)17)25-13-9-18(10-14-25)27-20-22-11-4-12-23-20;1-25-16-5-3-15(4-6-16)7-12-22-19(24)23-13-8-17(9-14-23)26-18-20-10-2-11-21-18;1-15(16-6-3-2-4-7-16)14-22-19(24)23-12-8-17(9-13-23)25-18-20-10-5-11-21-18;19-18(20,21)28-15-4-1-3-13(11-15)12-24-17(26)25-9-5-14(6-10-25)27-16-22-7-2-8-23-16;18-15-10-13(19)3-2-12(15)11-22-17(24)23-8-4-14(5-9-23)25-16-20-6-1-7-21-16;18-17(19,20)14-3-2-12(10-23-14)11-24-16(26)25-8-4-13(5-9-25)27-15-21-6-1-7-22-15/h1-12,16,22H,13-15,17-20H2,(H,28,30);1-9,13-14,22-23H,10-12,15-17H2,(H,30,32);1-8,11-12,18H,9-10,13-15H2,(H,24,26);2-6,10-11,17H,7-9,12-14H2,1H3,(H,22,24);2-7,10-11,15,17H,8-9,12-14H2,1H3,(H,22,24);1-4,7-8,11,14H,5-6,9-10,12H2,(H,24,26);1-3,6-7,10,14H,4-5,8-9,11H2,(H,22,24);1-3,6-7,10,13H,4-5,8-9,11H2,(H,24,26)/t;;;;15-;;;/m....1.../s1.
What are the key properties of N-[3,3-bis(4-fluorophenyl)propyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-(naphthalen-1-ylmethyl)-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-phenylphenyl)ethyl]-4-(pyridin-2-ylmethyl)piperidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]piperidine-1-carboxamide?
N-[3,3-bis(4-fluorophenyl)propyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-(naphthalen-1-ylmethyl)-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-phenylphenyl)ethyl]-4-(pyridin-2-ylmethyl)piperidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]piperidine-1-carboxamide has a molecular weight of 3053.86 g/mol, XLogP of 26.78, 41 rotatable bonds, 8 hydrogen bond donors, and 33 hydrogen bond acceptors.
Where does this data come from?
All data for N-[3,3-bis(4-fluorophenyl)propyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-(naphthalen-1-ylmethyl)-4-pyrimidin-2-yloxypiperidine-1-carboxamide;N-[2-(4-phenylphenyl)ethyl]-4-(pyridin-2-ylmethyl)piperidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-4-pyrimidin-2-yloxypiperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[3-(trifluoromethoxy)phenyl]methyl]piperidine-1-carboxamide;4-pyrimidin-2-yloxy-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]piperidine-1-carboxamide is sourced from PubChem (CID 158926093), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).