7-[(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(3,3-dimethyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(1,3-dioxo-2-azaspiro[4.4]nonan-2-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,4-dioxo-1,3-oxazolidin-3-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carbonitrile

C111H88F5N17O14 — CID 158930229

About 7-[(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(3,3-dimethyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(1,3-dioxo-2-azaspiro[4.4]nonan-2-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,4-dioxo-1,3-oxazolidin-3-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carbonitrile

7-[(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(3,3-dimethyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(1,3-dioxo-2-azaspiro[4.4]nonan-2-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,4-dioxo-1,3-oxazolidin-3-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carbonitrile (PubChem CID 158930229) has the molecular formula C111H88F5N17O14 and a molecular weight of 1979.02 g/mol. Its IUPAC name is 7-[(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(3,3-dimethyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(1,3-dioxo-2-azaspiro[4.4]nonan-2-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,4-dioxo-1,3-oxazolidin-3-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carbonitrile.

Molecular Properties

• Compound Name: 7-[(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(3,3-dimethyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(1,3-dioxo-2-azaspiro[4.4]nonan-2-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,4-dioxo-1,3-oxazolidin-3-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carbonitrile
• PubChem CID: 158930229
• Molecular Formula: C111H88F5N17O14
• Molecular Weight: 1979.02 g/mol
• Exact Mass: 1977.66
• IUPAC Name: 7-[(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(3,3-dimethyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(1,3-dioxo-2-azaspiro[4.4]nonan-2-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,4-dioxo-1,3-oxazolidin-3-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carbonitrile
• SMILES: CC1(C)CC(=O)N(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)C1=O.CC1(C)NC(=O)N(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)C1=O.CN1CC(=O)N(Cc2ccc3c(-c4ccc(F)cc4)cc(C#N)nc3c2)C1=O.N#Cc1cc(-c2ccc(F)cc2)c2ccc(CN3C(=O)COC3=O)cc2n1.NC(=O)c1cc(-c2ccc(F)cc2)c2ccc(CN3C(=O)CC4(CCCC4)C3=O)cc2n1
• InChI: InChI=1S/C25H22FN3O3.C23H20FN3O3.C22H19FN4O3.C21H15FN4O2.C20H12FN3O3/c26-17-6-4-16(5-7-17)19-12-21(23(27)31)28-20-11-15(3-8-18(19)20)14-29-22(30)13-25(24(29)32)9-1-2-10-25;1-23(2)11-20(28)27(22(23)30)12-13-3-8-16-17(14-4-6-15(24)7-5-14)10-19(21(25)29)26-18(16)9-13;1-22(2)20(29)27(21(30)26-22)11-12-3-8-15-16(13-4-6-14(23)7-5-13)10-18(19(24)28)25-17(15)9-12;1-25-12-20(27)26(21(25)28)11-13-2-7-17-18(14-3-5-15(22)6-4-14)9-16(10-23)24-19(17)8-13;21-14-4-2-13(3-5-14)17-8-15(9-22)23-18-7-12(1-6-16(17)18)10-24-19(25)11-27-20(24)26/h3-8,11-12H,1-2,9-10,13-14H2,(H2,27,31);3-10H,11-12H2,1-2H3,(H2,25,29);3-10H,11H2,1-2H3,(H2,24,28)(H,26,30);2-9H,11-12H2,1H3;1-8H,10-11H2
• InChIKey: JIYPFVSJTQQQSY-UHFFFAOYSA-N
• XLogP: 17.05
• TPSA: 452.70 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 21
• Rotatable Bonds: 18
• Heavy Atoms: 147
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1979.02
LogP ≤ 5	17.05
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	21

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydantoin', 'substructure': 'N/A'}, {'alert_name': 'phthalimide', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 7-[(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(3,3-dimethyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(1,3-dioxo-2-azaspiro[4.4]nonan-2-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,4-dioxo-1,3-oxazolidin-3-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carbonitrile?

The IUPAC name of 7-[(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(3,3-dimethyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(1,3-dioxo-2-azaspiro[4.4]nonan-2-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,4-dioxo-1,3-oxazolidin-3-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carbonitrile (CID 158930229) is 7-[(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(3,3-dimethyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(1,3-dioxo-2-azaspiro[4.4]nonan-2-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,4-dioxo-1,3-oxazolidin-3-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carbonitrile.

What is the SMILES notation for 7-[(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(3,3-dimethyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(1,3-dioxo-2-azaspiro[4.4]nonan-2-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,4-dioxo-1,3-oxazolidin-3-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carbonitrile?

The canonical SMILES for 7-[(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(3,3-dimethyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(1,3-dioxo-2-azaspiro[4.4]nonan-2-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,4-dioxo-1,3-oxazolidin-3-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carbonitrile is CC1(C)CC(=O)N(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)C1=O.CC1(C)NC(=O)N(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)C1=O.CN1CC(=O)N(Cc2ccc3c(-c4ccc(F)cc4)cc(C#N)nc3c2)C1=O.N#Cc1cc(-c2ccc(F)cc2)c2ccc(CN3C(=O)COC3=O)cc2n1.NC(=O)c1cc(-c2ccc(F)cc2)c2ccc(CN3C(=O)CC4(CCCC4)C3=O)cc2n1.

What is the InChIKey of 7-[(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(3,3-dimethyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(1,3-dioxo-2-azaspiro[4.4]nonan-2-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,4-dioxo-1,3-oxazolidin-3-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carbonitrile?

The InChIKey is JIYPFVSJTQQQSY-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H22FN3O3.C23H20FN3O3.C22H19FN4O3.C21H15FN4O2.C20H12FN3O3/c26-17-6-4-16(5-7-17)19-12-21(23(27)31)28-20-11-15(3-8-18(19)20)14-29-22(30)13-25(24(29)32)9-1-2-10-25;1-23(2)11-20(28)27(22(23)30)12-13-3-8-16-17(14-4-6-15(24)7-5-14)10-19(21(25)29)26-18(16)9-13;1-22(2)20(29)27(21(30)26-22)11-12-3-8-15-16(13-4-6-14(23)7-5-13)10-18(19(24)28)25-17(15)9-12;1-25-12-20(27)26(21(25)28)11-13-2-7-17-18(14-3-5-15(22)6-4-14)9-16(10-23)24-19(17)8-13;21-14-4-2-13(3-5-14)17-8-15(9-22)23-18-7-12(1-6-16(17)18)10-24-19(25)11-27-20(24)26/h3-8,11-12H,1-2,9-10,13-14H2,(H2,27,31);3-10H,11-12H2,1-2H3,(H2,25,29);3-10H,11H2,1-2H3,(H2,24,28)(H,26,30);2-9H,11-12H2,1H3;1-8H,10-11H2.

What are the key properties of 7-[(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(3,3-dimethyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(1,3-dioxo-2-azaspiro[4.4]nonan-2-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,4-dioxo-1,3-oxazolidin-3-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carbonitrile?

7-[(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(3,3-dimethyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(1,3-dioxo-2-azaspiro[4.4]nonan-2-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,4-dioxo-1,3-oxazolidin-3-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carbonitrile has a molecular weight of 1979.02 g/mol, XLogP of 17.05, 18 rotatable bonds, 4 hydrogen bond donors, and 21 hydrogen bond acceptors.

Where does this data come from?

All data for 7-[(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(3,3-dimethyl-2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(1,3-dioxo-2-azaspiro[4.4]nonan-2-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide;7-[(2,4-dioxo-1,3-oxazolidin-3-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carbonitrile;4-(4-fluorophenyl)-7-[(3-methyl-2,5-dioxoimidazolidin-1-yl)methyl]quinoline-2-carbonitrile is sourced from PubChem (CID 158930229), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).