N-benzyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-tert-butyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-(cyclopentylmethyl)-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-piperidin-4-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-propan-2-ylpyrazolo[1,5-a]pyrimidin-7-amine;2-[[3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-yl]amino]ethanol

C178H240BrN65O2 — CID 158934601

IUPACN-benzyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-tert-butyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-(cyclopentylmethyl)-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-piperidin-4-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-propan-2-ylpyrazolo[1,5-a]pyrimidin-7-amine;2-[[3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-yl]amino]ethanol
SMILESCC(C)Nc1cc(C2CCCNC2)nc2c(-c3cnn(C)c3)cnn12.Cn1cc(-c2cnn3c(NC(C)(C)C)cc(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NC4CCCC4)c(Br)c(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NC4CCCC4)cc(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NC4CCNCC4)cc(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NCC4CCCC4)cc(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NCCN4CCOCC4)cc(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NCCO)cc(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NCc4ccccc4)cc(C4CCCNC4)nc23)cn1
InChIInChI=1S/C22H25N7.C21H30N8O.C21H29N7.C20H26BrN7.C20H28N8.C20H27N7.C19H27N7.C18H25N7.C17H23N7O/c1-28-15-18(13-25-28)19-14-26-29-21(24-11-16-6-3-2-4-7-16)10-20(27-22(19)29)17-8-5-9-23-12-17;1-27-15-17(13-24-27)18-14-25-29-20(23-5-6-28-7-9-30-10-8-28)11-19(26-21(18)29)16-3-2-4-22-12-16;1-27-14-17(12-24-27)18-13-25-28-20(23-10-15-5-2-3-6-15)9-19(26-21(18)28)16-7-4-8-22-11-16;1-27-12-14(10-23-27)16-11-24-28-19(16)26-18(13-5-4-8-22-9-13)17(21)20(28)25-15-6-2-3-7-15;1-27-13-15(11-23-27)17-12-24-28-19(25-16-4-7-21-8-5-16)9-18(26-20(17)28)14-3-2-6-22-10-14;1-26-13-15(11-22-26)17-12-23-27-19(24-16-6-2-3-7-16)9-18(25-20(17)27)14-5-4-8-21-10-14;1-19(2,3)24-17-8-16(13-6-5-7-20-9-13)23-18-15(11-22-26(17)18)14-10-21-25(4)12-14;1-12(2)22-17-7-16(13-5-4-6-19-8-13)23-18-15(10-21-25(17)18)14-9-20-24(3)11-14;1-23-11-13(9-20-23)14-10-21-24-16(19-5-6-25)7-15(22-17(14)24)12-3-2-4-18-8-12/h2-4,6-7,10,13-15,17,23-24H,5,8-9,11-12H2,1H3;11,13-16,22-23H,2-10,12H2,1H3;9,12-16,22-23H,2-8,10-11H2,1H3;10-13,15,22,25H,2-9H2,1H3;9,11-14,16,21-22,25H,2-8,10H2,1H3;9,11-14,16,21,24H,2-8,10H2,1H3;8,10-13,20,24H,5-7,9H2,1-4H3;7,9-13,19,22H,4-6,8H2,1-3H3;7,9-12,18-19,25H,2-6,8H2,1H3
InChIKeyJJMKGHJTSDSJFE-UHFFFAOYSA-N
MW3402.23 g/mol
LogP22.40
Rot. Bonds40

About N-benzyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-tert-butyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-(cyclopentylmethyl)-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-piperidin-4-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-propan-2-ylpyrazolo[1,5-a]pyrimidin-7-amine;2-[[3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-yl]amino]ethanol

N-benzyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-tert-butyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-(cyclopentylmethyl)-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-piperidin-4-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-propan-2-ylpyrazolo[1,5-a]pyrimidin-7-amine;2-[[3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-yl]amino]ethanol (PubChem CID 158934601) has the molecular formula C178H240BrN65O2 and a molecular weight of 3402.23 g/mol. Its IUPAC name is N-benzyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-tert-butyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-(cyclopentylmethyl)-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-piperidin-4-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-propan-2-ylpyrazolo[1,5-a]pyrimidin-7-amine;2-[[3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-yl]amino]ethanol.

Molecular Properties

Compound NameN-benzyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-tert-butyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-(cyclopentylmethyl)-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-piperidin-4-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-propan-2-ylpyrazolo[1,5-a]pyrimidin-7-amine;2-[[3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-yl]amino]ethanol
PubChem CID158934601
Molecular FormulaC178H240BrN65O2
Molecular Weight3402.23 g/mol
Exact Mass3398.99
IUPAC NameN-benzyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-tert-butyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-(cyclopentylmethyl)-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-piperidin-4-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-propan-2-ylpyrazolo[1,5-a]pyrimidin-7-amine;2-[[3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-yl]amino]ethanol
SMILESCC(C)Nc1cc(C2CCCNC2)nc2c(-c3cnn(C)c3)cnn12.Cn1cc(-c2cnn3c(NC(C)(C)C)cc(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NC4CCCC4)c(Br)c(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NC4CCCC4)cc(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NC4CCNCC4)cc(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NCC4CCCC4)cc(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NCCN4CCOCC4)cc(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NCCO)cc(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NCc4ccccc4)cc(C4CCCNC4)nc23)cn1
InChIInChI=1S/C22H25N7.C21H30N8O.C21H29N7.C20H26BrN7.C20H28N8.C20H27N7.C19H27N7.C18H25N7.C17H23N7O/c1-28-15-18(13-25-28)19-14-26-29-21(24-11-16-6-3-2-4-7-16)10-20(27-22(19)29)17-8-5-9-23-12-17;1-27-15-17(13-24-27)18-14-25-29-20(23-5-6-28-7-9-30-10-8-28)11-19(26-21(18)29)16-3-2-4-22-12-16;1-27-14-17(12-24-27)18-13-25-28-20(23-10-15-5-2-3-6-15)9-19(26-21(18)28)16-7-4-8-22-11-16;1-27-12-14(10-23-27)16-11-24-28-19(16)26-18(13-5-4-8-22-9-13)17(21)20(28)25-15-6-2-3-7-15;1-27-13-15(11-23-27)17-12-24-28-19(25-16-4-7-21-8-5-16)9-18(26-20(17)28)14-3-2-6-22-10-14;1-26-13-15(11-22-26)17-12-23-27-19(24-16-6-2-3-7-16)9-18(25-20(17)27)14-5-4-8-21-10-14;1-19(2,3)24-17-8-16(13-6-5-7-20-9-13)23-18-15(11-22-26(17)18)14-10-21-25(4)12-14;1-12(2)22-17-7-16(13-5-4-6-19-8-13)23-18-15(10-21-25(17)18)14-9-20-24(3)11-14;1-23-11-13(9-20-23)14-10-21-24-16(19-5-6-25)7-15(22-17(14)24)12-3-2-4-18-8-12/h2-4,6-7,10,13-15,17,23-24H,5,8-9,11-12H2,1H3;11,13-16,22-23H,2-10,12H2,1H3;9,12-16,22-23H,2-8,10-11H2,1H3;10-13,15,22,25H,2-9H2,1H3;9,11-14,16,21-22,25H,2-8,10H2,1H3;9,11-14,16,21,24H,2-8,10H2,1H3;8,10-13,20,24H,5-7,9H2,1-4H3;7,9-13,19,22H,4-6,8H2,1-3H3;7,9-12,18-19,25H,2-6,8H2,1H3
InChIKeyJJMKGHJTSDSJFE-UHFFFAOYSA-N
XLogP22.40
TPSA693.36 Ų
H-Bond Donors20
H-Bond Acceptors67
Rotatable Bonds40
Heavy Atoms246
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003402.23
LogP ≤ 522.40
H-Bond Donors ≤ 520
H-Bond Acceptors ≤ 1067

Analyze N-benzyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-tert-butyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-(cyclopentylmethyl)-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-piperidin-4-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-propan-2-ylpyrazolo[1,5-a]pyrimidin-7-amine;2-[[3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-yl]amino]ethanol with MolForge

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Related Compounds

1-[4-[[8-[4-[[4-Fluoro-3-[2-[[1-(2-hydroxy-2-methylpropyl)pyrazol-4-yl]amino]-8-[4-(morpholin-4-ylmethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-5-yl]piperidin-1-yl]methyl]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]pyrazol-1-yl]-2-methylpropan-2-ol
CID 90877281
1-[(2R)-2-hydroxypropyl]-3-[4-(4-morpholin-4-ylpyrrolo[2,1-f][1,2,4]triazin-2-yl)phenyl]urea;5-(4-morpholin-4-yl-7-prop-1-en-2-ylpyrrolo[2,1-f][1,2,4]triazin-2-yl)pyrimidin-2-amine;1-[4-(4-morpholin-4-ylpyrrolo[2,1-f][1,2,4]triazin-2-yl)phenyl]-3-(2,2,2-trifluoroethyl)urea;5-(4-morpholin-4-ylpyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine;5-(4-morpholin-4-ylpyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyrimidin-2-amine
CID 159365484
3-bromo-5-(oxan-4-yl)-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine;3-ethyl-N-[(1-hydroxypyridin-1-ium-3-yl)methyl]-5-phenylpyrazolo[1,5-a]pyrimidin-7-amine;N-[(1-hydroxypyridin-1-ium-3-yl)methyl]-5-phenyl-3-(2,2,2-trifluoroethyl)pyrazolo[1,5-a]pyrimidin-7-amine;5-phenyl-N-(pyridin-3-ylmethyl)-3-(2,2,2-trifluoroethyl)pyrazolo[1,5-a]pyrimidin-7-amine
CID 159700391
3-[(3-bromoindolizin-6-yl)methyl]-5-(1-methylpyrazol-4-yl)triazolo[4,5-b]pyrazine;5-(1-ethylpyrazol-4-yl)-3-(indolizin-6-ylmethyl)triazolo[4,5-b]pyrazine;3-[(1S)-1-indolizin-6-ylethyl]-5-(1-methylpyrazol-4-yl)triazolo[4,5-b]pyrazine;5-(1-methylpyrazol-4-yl)-3-(7H-pyrrolo[3,4-b]pyridin-5-ylmethyl)triazolo[4,5-b]pyrazine;3-(pyrrolo[1,2-b]pyridazin-2-ylmethyl)-5-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]triazolo[4,5-b]pyrazine;2-[4-[3-(1H-pyrrolo[2,3-b]pyridin-2-ylmethyl)triazolo[4,5-b]pyrazin-5-yl]pyrazol-1-yl]ethanol
CID 160544267
3,3-difluoro-N-[(1R,3S)-3-[[5-fluoro-2-(1-methylpyrazolo[5,4-b]pyridin-3-yl)pyrimidin-4-yl]amino]cyclohexyl]pyrrolidine-1-carboxamide;(3R)-3-fluoro-N-[(1R)-3-[[5-fluoro-2-(5-fluoro-1-methylpyrazolo[5,4-b]pyridin-3-yl)pyrimidin-4-yl]methyl]cyclohexyl]pyrrolidine-1-carboxamide;N-[(1R)-3-[[5-fluoro-2-(5-fluoro-1-methylpyrazolo[5,4-b]pyridin-3-yl)pyrimidin-4-yl]methyl]cyclohexyl]morpholine-4-carboxamide;(2S)-N-[(1R,3S)-3-[[5-fluoro-2-(1-methylpyrazolo[5,4-b]pyridin-3-yl)pyrimidin-4-yl]amino]cyclohexyl]-2-methylpyrrolidine-1-carboxamide;N-[(1R,3S)-3-[[5-fluoro-2-(1-methylpyrazolo[5,4-b]pyridin-3-yl)pyrimidin-4-yl]amino]cyclohexyl]piperidine-1-carboxamide;N-[(1R)-3-[[5-fluoro-2-(1-methylpyrazolo[5,4-b]pyridin-3-yl)pyrimidin-4-yl]methyl]cyclohexyl]pyrrolidine-1-carboxamide
CID 160957594
6-[[bis[(6-amino-2-pyridinyl)methyl]amino]methyl]pyridin-2-amine;2-(3,5-dimethylpyrazol-1-yl)-N,N-bis[2-(3,5-dimethylpyrazol-1-yl)ethyl]ethanamine;bis(1-(3,5-dimethylpyrazol-1-yl)-N,N-bis[(3,5-dimethylpyrazol-1-yl)methyl]methanamine);1-(3,5-dimethyl-1,2,4-triazol-1-yl)-N,N-bis[(3,5-dimethyl-1,2,4-triazol-1-yl)methyl]methanamine;1-(6-methyl-2-pyridinyl)-N,N-bis[(6-methyl-2-pyridinyl)methyl]methanamine;1-morpholin-3-yl-N,N-bis(morpholin-3-ylmethyl)methanamine;1-piperidin-2-yl-N,N-bis(piperidin-2-ylmethyl)methanamine;2-pyrazol-1-yl-N,N-bis(2-pyrazol-1-ylethyl)ethanamine;1-[6-(trifluoromethyl)-2-pyridinyl]-N,N-bis[[6-(trifluoromethyl)-2-pyridinyl]methyl]methanamine
CID 162090366
(3R)-4-[6-[1-(azetidin-3-ylmethyl)-3,5-dimethylpyrazol-4-yl]-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl]-3-methylmorpholine;(3R)-4-[6-[2-(difluoromethyl)-4-pyridinyl]-2-(1,3,5-trimethylpyrazol-4-yl)pyrimidin-4-yl]-3-methylmorpholine;(3R)-4-[6-(3,5-dimethyl-1-piperidin-4-ylpyrazol-4-yl)-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl]-3-methylmorpholine;(3R)-4-[6-[1,5-dimethyl-3-(trifluoromethyl)pyrazol-4-yl]-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl]-3-methylmorpholine
CID 167598752
2-[[3-(3,3-difluoropyrrolidin-1-yl)azetidin-1-yl]methyl]-8-propan-2-yl-7-[(2-pyrazol-1-ylphenyl)methyl]pyrazolo[1,5-a][1,3,5]triazin-4-amine;2-[[methyl(3-piperidin-1-ylpropyl)amino]methyl]-8-propan-2-yl-7-[(2-pyrazol-1-ylphenyl)methyl]pyrazolo[1,5-a][1,3,5]triazin-4-amine;2-[[methyl(2-pyrrolidin-1-ylethyl)amino]methyl]-8-propan-2-yl-N-[(2-pyrazol-1-ylphenyl)methyl]pyrazolo[1,5-a][1,3,5]triazin-4-amine;2-[(2-morpholin-4-ylethylamino)methyl]-8-propan-2-yl-7-[(2-pyrazol-1-ylphenyl)methyl]pyrazolo[1,5-a][1,3,5]triazin-4-amine;8-propan-2-yl-7-[(2-pyrazol-1-ylphenyl)methyl]-2-[(2-pyrrolidin-1-ylethylamino)methyl]pyrazolo[1,5-a][1,3,5]triazin-4-amine
CID 173668939
5-[(1R,3R)-3-[4-[7-amino-5-[(1R,3S)-3-[4-[7-amino-5-[(1R,3R)-3-aminocyclopentyl]pyrazolo[1,5-a]pyrimidin-3-yl]-1-methylpyrrol-2-yl]cyclopentyl]pyrazolo[1,5-a]pyrimidin-3-yl]-1-methylpyrrol-2-yl]cyclopentyl]-6-bromo-3-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine
CID 58853459
[(1R,2S,5S)-3-[3-bromo-7-[[6-[(3S)-3-[[3-bromo-7-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-5-yl]-methylamino]-2-methylbutan-2-yl]-3-pyridinyl]methylamino]pyrazolo[1,5-a]pyrimidin-5-yl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2-yl]methanol
CID 70806305
[(1R,2S,5S)-6-[5-[[[5-[(4-aminocyclohexyl)amino]-3-bromopyrazolo[1,5-a]pyrimidin-7-yl]amino]methyl]-2-pyridinyl]-3-[3-bromo-7-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-5-yl]-6-methyl-3-azabicyclo[3.1.0]hexan-2-yl]methanol
CID 70877112
[(1R,2S,5S)-6-[5-[[[3-bromo-5-[[4-(methylamino)cyclohexyl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]amino]methyl]-2-pyridinyl]-3-[3-bromo-7-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-5-yl]-6-methyl-3-azabicyclo[3.1.0]hexan-2-yl]methanol
CID 70878984

Frequently Asked Questions

What is the IUPAC name of N-benzyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-tert-butyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-(cyclopentylmethyl)-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-piperidin-4-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-propan-2-ylpyrazolo[1,5-a]pyrimidin-7-amine;2-[[3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-yl]amino]ethanol?
The IUPAC name of N-benzyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-tert-butyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-(cyclopentylmethyl)-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-piperidin-4-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-propan-2-ylpyrazolo[1,5-a]pyrimidin-7-amine;2-[[3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-yl]amino]ethanol (CID 158934601) is N-benzyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-tert-butyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-(cyclopentylmethyl)-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-piperidin-4-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-propan-2-ylpyrazolo[1,5-a]pyrimidin-7-amine;2-[[3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-yl]amino]ethanol.
What is the SMILES notation for N-benzyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-tert-butyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-(cyclopentylmethyl)-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-piperidin-4-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-propan-2-ylpyrazolo[1,5-a]pyrimidin-7-amine;2-[[3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-yl]amino]ethanol?
The canonical SMILES for N-benzyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-tert-butyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-(cyclopentylmethyl)-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-piperidin-4-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-propan-2-ylpyrazolo[1,5-a]pyrimidin-7-amine;2-[[3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-yl]amino]ethanol is CC(C)Nc1cc(C2CCCNC2)nc2c(-c3cnn(C)c3)cnn12.Cn1cc(-c2cnn3c(NC(C)(C)C)cc(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NC4CCCC4)c(Br)c(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NC4CCCC4)cc(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NC4CCNCC4)cc(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NCC4CCCC4)cc(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NCCN4CCOCC4)cc(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NCCO)cc(C4CCCNC4)nc23)cn1.Cn1cc(-c2cnn3c(NCc4ccccc4)cc(C4CCCNC4)nc23)cn1.
What is the InChIKey of N-benzyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-tert-butyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-(cyclopentylmethyl)-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-piperidin-4-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-propan-2-ylpyrazolo[1,5-a]pyrimidin-7-amine;2-[[3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-yl]amino]ethanol?
The InChIKey is JJMKGHJTSDSJFE-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H25N7.C21H30N8O.C21H29N7.C20H26BrN7.C20H28N8.C20H27N7.C19H27N7.C18H25N7.C17H23N7O/c1-28-15-18(13-25-28)19-14-26-29-21(24-11-16-6-3-2-4-7-16)10-20(27-22(19)29)17-8-5-9-23-12-17;1-27-15-17(13-24-27)18-14-25-29-20(23-5-6-28-7-9-30-10-8-28)11-19(26-21(18)29)16-3-2-4-22-12-16;1-27-14-17(12-24-27)18-13-25-28-20(23-10-15-5-2-3-6-15)9-19(26-21(18)28)16-7-4-8-22-11-16;1-27-12-14(10-23-27)16-11-24-28-19(16)26-18(13-5-4-8-22-9-13)17(21)20(28)25-15-6-2-3-7-15;1-27-13-15(11-23-27)17-12-24-28-19(25-16-4-7-21-8-5-16)9-18(26-20(17)28)14-3-2-6-22-10-14;1-26-13-15(11-22-26)17-12-23-27-19(24-16-6-2-3-7-16)9-18(25-20(17)27)14-5-4-8-21-10-14;1-19(2,3)24-17-8-16(13-6-5-7-20-9-13)23-18-15(11-22-26(17)18)14-10-21-25(4)12-14;1-12(2)22-17-7-16(13-5-4-6-19-8-13)23-18-15(10-21-25(17)18)14-9-20-24(3)11-14;1-23-11-13(9-20-23)14-10-21-24-16(19-5-6-25)7-15(22-17(14)24)12-3-2-4-18-8-12/h2-4,6-7,10,13-15,17,23-24H,5,8-9,11-12H2,1H3;11,13-16,22-23H,2-10,12H2,1H3;9,12-16,22-23H,2-8,10-11H2,1H3;10-13,15,22,25H,2-9H2,1H3;9,11-14,16,21-22,25H,2-8,10H2,1H3;9,11-14,16,21,24H,2-8,10H2,1H3;8,10-13,20,24H,5-7,9H2,1-4H3;7,9-13,19,22H,4-6,8H2,1-3H3;7,9-12,18-19,25H,2-6,8H2,1H3.
What are the key properties of N-benzyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-tert-butyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-(cyclopentylmethyl)-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-piperidin-4-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-propan-2-ylpyrazolo[1,5-a]pyrimidin-7-amine;2-[[3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-yl]amino]ethanol?
N-benzyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-tert-butyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-(cyclopentylmethyl)-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-piperidin-4-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-propan-2-ylpyrazolo[1,5-a]pyrimidin-7-amine;2-[[3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-yl]amino]ethanol has a molecular weight of 3402.23 g/mol, XLogP of 22.40, 40 rotatable bonds, 20 hydrogen bond donors, and 67 hydrogen bond acceptors.
Where does this data come from?
All data for N-benzyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;6-bromo-N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-tert-butyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-(cyclopentylmethyl)-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;N-cyclopentyl-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-N-(2-morpholin-4-ylethyl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-piperidin-4-ylpyrazolo[1,5-a]pyrimidin-7-amine;3-(1-methylpyrazol-4-yl)-5-piperidin-3-yl-N-propan-2-ylpyrazolo[1,5-a]pyrimidin-7-amine;2-[[3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-yl]amino]ethanol is sourced from PubChem (CID 158934601), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).