2-[4-[2-[(1-cyclopentyl-3-methylpyrazol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-[(5-cyclopropyl-2H-pyrrol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-(3,4-dihydro-2H-pyrrolo[2,1-b][1,3]oxazin-8-ylmethyl)pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(1-methyl-6-methylidene-3-pyridinyl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(3H-pyrrol-5-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-3-yl]acetamide;2-[4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide

C242H214F35N47O19 — CID 158939175

IUPAC2-[4-[2-[(1-cyclopentyl-3-methylpyrazol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-[(5-cyclopropyl-2H-pyrrol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-(3,4-dihydro-2H-pyrrolo[2,1-b][1,3]oxazin-8-ylmethyl)pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(1-methyl-6-methylidene-3-pyridinyl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(3H-pyrrol-5-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-3-yl]acetamide;2-[4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide
SMILESC=C1C=CC(Cc2ncc(-c3ccc(CC(=O)Nc4cc(C5(C(F)(F)F)CC5)on4)c(F)c3)cn2)=CN1C.CC(C)(c1cc(NC(=O)Cc2ccc(-c3cnc(Cc4ccn5c4CCCC5)nc3)cc2F)no1)C(F)(F)F.Cc1cc(Cc2ncc(-c3ccc(CC(=O)Nc4cc(C5(C(F)(F)F)CC5)on4)c(F)c3)cn2)n[nH]1.Cc1nn(C2CCCC2)cc1Cc1ncc(-c2ccc(CC(=O)Nc3cc(C4(C(F)(F)F)CC4)on3)c(F)c2)cn1.O=C(Cc1ccc(-c2cnc(CC3=CCC=N3)nc2)cc1F)Nc1cc(C2(C(F)(F)F)CC2)on1.O=C(Cc1ccc(-c2cnc(CC3=CCN=C3C3CC3)nc2)cc1F)Nc1cc(C2(C(F)(F)F)CC2)on1.O=C(Cc1ccc(-c2cnc(Cc3ccn4c3CCCC4)nc2)cc1)Nc1cc(C2(C(F)(F)F)CC2)on1.O=C(Cc1ccc(-c2cnc(Cc3ccn4c3CCCC4)nc2)cc1F)Nc1cc(C2(C(F)(F)F)CC2)on1.O=C(Cc1ccc(-c2cnc(Cc3ccn4c3OCCC4)nc2)cc1F)Nc1cc(C2(C(F)(F)F)CC2)on1
InChIInChI=1S/C29H28F4N6O2.C28H25F4N5O2.C28H27F4N5O2.C28H26F3N5O2.C27H23F4N5O3.2C27H23F4N5O2.C24H20F4N6O2.C24H19F4N5O2/c1-17-20(16-39(37-17)22-4-2-3-5-22)11-25-34-14-21(15-35-25)18-6-7-19(23(30)10-18)12-27(40)36-26-13-24(41-38-26)28(8-9-28)29(31,32)33;29-21-11-17(20-15-33-24(34-16-20)12-19-6-10-37-9-2-1-3-22(19)37)4-5-18(21)13-26(38)35-25-14-23(39-36-25)27(7-8-27)28(30,31)32;1-27(2,28(30,31)32)23-14-25(36-39-23)35-26(38)13-18-7-6-17(11-21(18)29)20-15-33-24(34-16-20)12-19-8-10-37-9-4-3-5-22(19)37;29-28(30,31)27(9-10-27)23-15-25(35-38-23)34-26(37)13-18-4-6-19(7-5-18)21-16-32-24(33-17-21)14-20-8-12-36-11-2-1-3-22(20)36;28-20-10-16(19-14-32-22(33-15-19)11-18-4-8-36-7-1-9-38-25(18)36)2-3-17(20)12-24(37)34-23-13-21(39-35-23)26(5-6-26)27(29,30)31;28-20-9-16(19-13-33-22(34-14-19)10-18-5-8-32-25(18)15-1-2-15)3-4-17(20)11-24(37)35-23-12-21(38-36-23)26(6-7-26)27(29,30)31;1-16-3-4-17(15-36(16)2)9-23-32-13-20(14-33-23)18-5-6-19(21(28)10-18)11-25(37)34-24-12-22(38-35-24)26(7-8-26)27(29,30)31;1-13-6-17(33-32-13)9-20-29-11-16(12-30-20)14-2-3-15(18(25)7-14)8-22(35)31-21-10-19(36-34-21)23(4-5-23)24(26,27)28;25-18-8-14(16-12-30-20(31-13-16)10-17-2-1-7-29-17)3-4-15(18)9-22(34)32-21-11-19(35-33-21)23(5-6-23)24(26,27)28/h6-7,10,13-16,22H,2-5,8-9,11-12H2,1H3,(H,36,38,40);4-6,10-11,14-16H,1-3,7-9,12-13H2,(H,35,36,38);6-8,10-11,14-16H,3-5,9,12-13H2,1-2H3,(H,35,36,38);4-8,12,15-17H,1-3,9-11,13-14H2,(H,34,35,37);2-4,8,10,13-15H,1,5-7,9,11-12H2,(H,34,35,37);3-5,9,12-15H,1-2,6-8,10-11H2,(H,35,36,37);3-6,10,12-15H,1,7-9,11H2,2H3,(H,34,35,37);2-3,6-7,10-12H,4-5,8-9H2,1H3,(H,32,33)(H,31,34,35);2-4,7-8,11-13H,1,5-6,9-10H2,(H,32,33,34)
InChIKeyJKANPJAZEDPNGG-UHFFFAOYSA-N
MW4749.61 g/mol
LogP49.39
Rot. Bonds65

About 2-[4-[2-[(1-cyclopentyl-3-methylpyrazol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-[(5-cyclopropyl-2H-pyrrol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-(3,4-dihydro-2H-pyrrolo[2,1-b][1,3]oxazin-8-ylmethyl)pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(1-methyl-6-methylidene-3-pyridinyl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(3H-pyrrol-5-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-3-yl]acetamide;2-[4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide

2-[4-[2-[(1-cyclopentyl-3-methylpyrazol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-[(5-cyclopropyl-2H-pyrrol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-(3,4-dihydro-2H-pyrrolo[2,1-b][1,3]oxazin-8-ylmethyl)pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(1-methyl-6-methylidene-3-pyridinyl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(3H-pyrrol-5-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-3-yl]acetamide;2-[4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide (PubChem CID 158939175) has the molecular formula C242H214F35N47O19 and a molecular weight of 4749.61 g/mol. Its IUPAC name is 2-[4-[2-[(1-cyclopentyl-3-methylpyrazol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-[(5-cyclopropyl-2H-pyrrol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-(3,4-dihydro-2H-pyrrolo[2,1-b][1,3]oxazin-8-ylmethyl)pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(1-methyl-6-methylidene-3-pyridinyl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(3H-pyrrol-5-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-3-yl]acetamide;2-[4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide.

Molecular Properties

Compound Name2-[4-[2-[(1-cyclopentyl-3-methylpyrazol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-[(5-cyclopropyl-2H-pyrrol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-(3,4-dihydro-2H-pyrrolo[2,1-b][1,3]oxazin-8-ylmethyl)pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(1-methyl-6-methylidene-3-pyridinyl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(3H-pyrrol-5-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-3-yl]acetamide;2-[4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide
PubChem CID158939175
Molecular FormulaC242H214F35N47O19
Molecular Weight4749.61 g/mol
Exact Mass4746.67
IUPAC Name2-[4-[2-[(1-cyclopentyl-3-methylpyrazol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-[(5-cyclopropyl-2H-pyrrol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-(3,4-dihydro-2H-pyrrolo[2,1-b][1,3]oxazin-8-ylmethyl)pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(1-methyl-6-methylidene-3-pyridinyl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(3H-pyrrol-5-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-3-yl]acetamide;2-[4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide
SMILESC=C1C=CC(Cc2ncc(-c3ccc(CC(=O)Nc4cc(C5(C(F)(F)F)CC5)on4)c(F)c3)cn2)=CN1C.CC(C)(c1cc(NC(=O)Cc2ccc(-c3cnc(Cc4ccn5c4CCCC5)nc3)cc2F)no1)C(F)(F)F.Cc1cc(Cc2ncc(-c3ccc(CC(=O)Nc4cc(C5(C(F)(F)F)CC5)on4)c(F)c3)cn2)n[nH]1.Cc1nn(C2CCCC2)cc1Cc1ncc(-c2ccc(CC(=O)Nc3cc(C4(C(F)(F)F)CC4)on3)c(F)c2)cn1.O=C(Cc1ccc(-c2cnc(CC3=CCC=N3)nc2)cc1F)Nc1cc(C2(C(F)(F)F)CC2)on1.O=C(Cc1ccc(-c2cnc(CC3=CCN=C3C3CC3)nc2)cc1F)Nc1cc(C2(C(F)(F)F)CC2)on1.O=C(Cc1ccc(-c2cnc(Cc3ccn4c3CCCC4)nc2)cc1)Nc1cc(C2(C(F)(F)F)CC2)on1.O=C(Cc1ccc(-c2cnc(Cc3ccn4c3CCCC4)nc2)cc1F)Nc1cc(C2(C(F)(F)F)CC2)on1.O=C(Cc1ccc(-c2cnc(Cc3ccn4c3OCCC4)nc2)cc1F)Nc1cc(C2(C(F)(F)F)CC2)on1
InChIInChI=1S/C29H28F4N6O2.C28H25F4N5O2.C28H27F4N5O2.C28H26F3N5O2.C27H23F4N5O3.2C27H23F4N5O2.C24H20F4N6O2.C24H19F4N5O2/c1-17-20(16-39(37-17)22-4-2-3-5-22)11-25-34-14-21(15-35-25)18-6-7-19(23(30)10-18)12-27(40)36-26-13-24(41-38-26)28(8-9-28)29(31,32)33;29-21-11-17(20-15-33-24(34-16-20)12-19-6-10-37-9-2-1-3-22(19)37)4-5-18(21)13-26(38)35-25-14-23(39-36-25)27(7-8-27)28(30,31)32;1-27(2,28(30,31)32)23-14-25(36-39-23)35-26(38)13-18-7-6-17(11-21(18)29)20-15-33-24(34-16-20)12-19-8-10-37-9-4-3-5-22(19)37;29-28(30,31)27(9-10-27)23-15-25(35-38-23)34-26(37)13-18-4-6-19(7-5-18)21-16-32-24(33-17-21)14-20-8-12-36-11-2-1-3-22(20)36;28-20-10-16(19-14-32-22(33-15-19)11-18-4-8-36-7-1-9-38-25(18)36)2-3-17(20)12-24(37)34-23-13-21(39-35-23)26(5-6-26)27(29,30)31;28-20-9-16(19-13-33-22(34-14-19)10-18-5-8-32-25(18)15-1-2-15)3-4-17(20)11-24(37)35-23-12-21(38-36-23)26(6-7-26)27(29,30)31;1-16-3-4-17(15-36(16)2)9-23-32-13-20(14-33-23)18-5-6-19(21(28)10-18)11-25(37)34-24-12-22(38-35-24)26(7-8-26)27(29,30)31;1-13-6-17(33-32-13)9-20-29-11-16(12-30-20)14-2-3-15(18(25)7-14)8-22(35)31-21-10-19(36-34-21)23(4-5-23)24(26,27)28;25-18-8-14(16-12-30-20(31-13-16)10-17-2-1-7-29-17)3-4-15(18)9-22(34)32-21-11-19(35-33-21)23(5-6-23)24(26,27)28/h6-7,10,13-16,22H,2-5,8-9,11-12H2,1H3,(H,36,38,40);4-6,10-11,14-16H,1-3,7-9,12-13H2,(H,35,36,38);6-8,10-11,14-16H,3-5,9,12-13H2,1-2H3,(H,35,36,38);4-8,12,15-17H,1-3,9-11,13-14H2,(H,34,35,37);2-4,8,10,13-15H,1,5-7,9,11-12H2,(H,34,35,37);3-5,9,12-15H,1-2,6-8,10-11H2,(H,35,36,37);3-6,10,12-15H,1,7-9,11H2,2H3,(H,34,35,37);2-3,6-7,10-12H,4-5,8-9H2,1H3,(H,32,33)(H,31,34,35);2-4,7-8,11-13H,1,5-6,9-10H2,(H,32,33,34)
InChIKeyJKANPJAZEDPNGG-UHFFFAOYSA-N
XLogP49.39
TPSA831.60 Ų
H-Bond Donors10
H-Bond Acceptors56
Rotatable Bonds65
Heavy Atoms343
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004749.61
LogP ≤ 549.39
H-Bond Donors ≤ 510
H-Bond Acceptors ≤ 1056

Analyze 2-[4-[2-[(1-cyclopentyl-3-methylpyrazol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-[(5-cyclopropyl-2H-pyrrol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-(3,4-dihydro-2H-pyrrolo[2,1-b][1,3]oxazin-8-ylmethyl)pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(1-methyl-6-methylidene-3-pyridinyl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(3H-pyrrol-5-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-3-yl]acetamide;2-[4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of 2-[4-[2-[(1-cyclopentyl-3-methylpyrazol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-[(5-cyclopropyl-2H-pyrrol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-(3,4-dihydro-2H-pyrrolo[2,1-b][1,3]oxazin-8-ylmethyl)pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(1-methyl-6-methylidene-3-pyridinyl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(3H-pyrrol-5-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-3-yl]acetamide;2-[4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide?
The IUPAC name of 2-[4-[2-[(1-cyclopentyl-3-methylpyrazol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-[(5-cyclopropyl-2H-pyrrol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-(3,4-dihydro-2H-pyrrolo[2,1-b][1,3]oxazin-8-ylmethyl)pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(1-methyl-6-methylidene-3-pyridinyl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(3H-pyrrol-5-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-3-yl]acetamide;2-[4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide (CID 158939175) is 2-[4-[2-[(1-cyclopentyl-3-methylpyrazol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-[(5-cyclopropyl-2H-pyrrol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-(3,4-dihydro-2H-pyrrolo[2,1-b][1,3]oxazin-8-ylmethyl)pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(1-methyl-6-methylidene-3-pyridinyl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(3H-pyrrol-5-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-3-yl]acetamide;2-[4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide.
What is the SMILES notation for 2-[4-[2-[(1-cyclopentyl-3-methylpyrazol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-[(5-cyclopropyl-2H-pyrrol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-(3,4-dihydro-2H-pyrrolo[2,1-b][1,3]oxazin-8-ylmethyl)pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(1-methyl-6-methylidene-3-pyridinyl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(3H-pyrrol-5-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-3-yl]acetamide;2-[4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide?
The canonical SMILES for 2-[4-[2-[(1-cyclopentyl-3-methylpyrazol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-[(5-cyclopropyl-2H-pyrrol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-(3,4-dihydro-2H-pyrrolo[2,1-b][1,3]oxazin-8-ylmethyl)pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(1-methyl-6-methylidene-3-pyridinyl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(3H-pyrrol-5-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-3-yl]acetamide;2-[4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide is C=C1C=CC(Cc2ncc(-c3ccc(CC(=O)Nc4cc(C5(C(F)(F)F)CC5)on4)c(F)c3)cn2)=CN1C.CC(C)(c1cc(NC(=O)Cc2ccc(-c3cnc(Cc4ccn5c4CCCC5)nc3)cc2F)no1)C(F)(F)F.Cc1cc(Cc2ncc(-c3ccc(CC(=O)Nc4cc(C5(C(F)(F)F)CC5)on4)c(F)c3)cn2)n[nH]1.Cc1nn(C2CCCC2)cc1Cc1ncc(-c2ccc(CC(=O)Nc3cc(C4(C(F)(F)F)CC4)on3)c(F)c2)cn1.O=C(Cc1ccc(-c2cnc(CC3=CCC=N3)nc2)cc1F)Nc1cc(C2(C(F)(F)F)CC2)on1.O=C(Cc1ccc(-c2cnc(CC3=CCN=C3C3CC3)nc2)cc1F)Nc1cc(C2(C(F)(F)F)CC2)on1.O=C(Cc1ccc(-c2cnc(Cc3ccn4c3CCCC4)nc2)cc1)Nc1cc(C2(C(F)(F)F)CC2)on1.O=C(Cc1ccc(-c2cnc(Cc3ccn4c3CCCC4)nc2)cc1F)Nc1cc(C2(C(F)(F)F)CC2)on1.O=C(Cc1ccc(-c2cnc(Cc3ccn4c3OCCC4)nc2)cc1F)Nc1cc(C2(C(F)(F)F)CC2)on1.
What is the InChIKey of 2-[4-[2-[(1-cyclopentyl-3-methylpyrazol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-[(5-cyclopropyl-2H-pyrrol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-(3,4-dihydro-2H-pyrrolo[2,1-b][1,3]oxazin-8-ylmethyl)pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(1-methyl-6-methylidene-3-pyridinyl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(3H-pyrrol-5-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-3-yl]acetamide;2-[4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide?
The InChIKey is JKANPJAZEDPNGG-UHFFFAOYSA-N. The full InChI is InChI=1S/C29H28F4N6O2.C28H25F4N5O2.C28H27F4N5O2.C28H26F3N5O2.C27H23F4N5O3.2C27H23F4N5O2.C24H20F4N6O2.C24H19F4N5O2/c1-17-20(16-39(37-17)22-4-2-3-5-22)11-25-34-14-21(15-35-25)18-6-7-19(23(30)10-18)12-27(40)36-26-13-24(41-38-26)28(8-9-28)29(31,32)33;29-21-11-17(20-15-33-24(34-16-20)12-19-6-10-37-9-2-1-3-22(19)37)4-5-18(21)13-26(38)35-25-14-23(39-36-25)27(7-8-27)28(30,31)32;1-27(2,28(30,31)32)23-14-25(36-39-23)35-26(38)13-18-7-6-17(11-21(18)29)20-15-33-24(34-16-20)12-19-8-10-37-9-4-3-5-22(19)37;29-28(30,31)27(9-10-27)23-15-25(35-38-23)34-26(37)13-18-4-6-19(7-5-18)21-16-32-24(33-17-21)14-20-8-12-36-11-2-1-3-22(20)36;28-20-10-16(19-14-32-22(33-15-19)11-18-4-8-36-7-1-9-38-25(18)36)2-3-17(20)12-24(37)34-23-13-21(39-35-23)26(5-6-26)27(29,30)31;28-20-9-16(19-13-33-22(34-14-19)10-18-5-8-32-25(18)15-1-2-15)3-4-17(20)11-24(37)35-23-12-21(38-36-23)26(6-7-26)27(29,30)31;1-16-3-4-17(15-36(16)2)9-23-32-13-20(14-33-23)18-5-6-19(21(28)10-18)11-25(37)34-24-12-22(38-35-24)26(7-8-26)27(29,30)31;1-13-6-17(33-32-13)9-20-29-11-16(12-30-20)14-2-3-15(18(25)7-14)8-22(35)31-21-10-19(36-34-21)23(4-5-23)24(26,27)28;25-18-8-14(16-12-30-20(31-13-16)10-17-2-1-7-29-17)3-4-15(18)9-22(34)32-21-11-19(35-33-21)23(5-6-23)24(26,27)28/h6-7,10,13-16,22H,2-5,8-9,11-12H2,1H3,(H,36,38,40);4-6,10-11,14-16H,1-3,7-9,12-13H2,(H,35,36,38);6-8,10-11,14-16H,3-5,9,12-13H2,1-2H3,(H,35,36,38);4-8,12,15-17H,1-3,9-11,13-14H2,(H,34,35,37);2-4,8,10,13-15H,1,5-7,9,11-12H2,(H,34,35,37);3-5,9,12-15H,1-2,6-8,10-11H2,(H,35,36,37);3-6,10,12-15H,1,7-9,11H2,2H3,(H,34,35,37);2-3,6-7,10-12H,4-5,8-9H2,1H3,(H,32,33)(H,31,34,35);2-4,7-8,11-13H,1,5-6,9-10H2,(H,32,33,34).
What are the key properties of 2-[4-[2-[(1-cyclopentyl-3-methylpyrazol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-[(5-cyclopropyl-2H-pyrrol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-(3,4-dihydro-2H-pyrrolo[2,1-b][1,3]oxazin-8-ylmethyl)pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(1-methyl-6-methylidene-3-pyridinyl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(3H-pyrrol-5-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-3-yl]acetamide;2-[4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide?
2-[4-[2-[(1-cyclopentyl-3-methylpyrazol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-[(5-cyclopropyl-2H-pyrrol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-(3,4-dihydro-2H-pyrrolo[2,1-b][1,3]oxazin-8-ylmethyl)pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(1-methyl-6-methylidene-3-pyridinyl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(3H-pyrrol-5-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-3-yl]acetamide;2-[4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide has a molecular weight of 4749.61 g/mol, XLogP of 49.39, 65 rotatable bonds, 10 hydrogen bond donors, and 56 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[4-[2-[(1-cyclopentyl-3-methylpyrazol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-[(5-cyclopropyl-2H-pyrrol-4-yl)methyl]pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[4-[2-(3,4-dihydro-2H-pyrrolo[2,1-b][1,3]oxazin-8-ylmethyl)pyrimidin-5-yl]-2-fluorophenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(1-methyl-6-methylidene-3-pyridinyl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-[(5-methyl-1H-pyrazol-3-yl)methyl]pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(3H-pyrrol-5-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide;2-[2-fluoro-4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-(1,1,1-trifluoro-2-methylpropan-2-yl)-1,2-oxazol-3-yl]acetamide;2-[4-[2-(5,6,7,8-tetrahydroindolizin-1-ylmethyl)pyrimidin-5-yl]phenyl]-N-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]acetamide is sourced from PubChem (CID 158939175), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).