6-(6-amino-3-pyridinyl)-N-(4-fluorophenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(2-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(3-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;3-[[6-(2-aminopyrimidin-5-yl)-2-morpholin-4-ylpyrimidin-4-yl]amino]benzonitrile;5-[2-morpholin-4-yl-6-(2H-tetrazol-5-yl)pyrimidin-4-yl]pyridin-2-amine

C90H94FN37O7 — CID 158958316

IUPAC6-(6-amino-3-pyridinyl)-N-(4-fluorophenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(2-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(3-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;3-[[6-(2-aminopyrimidin-5-yl)-2-morpholin-4-ylpyrimidin-4-yl]amino]benzonitrile;5-[2-morpholin-4-yl-6-(2H-tetrazol-5-yl)pyrimidin-4-yl]pyridin-2-amine
SMILESCOc1cccc(Nc2cc(-c3cnc(N)nc3)nc(N3CCOCC3)n2)c1.COc1ccccc1Nc1cc(-c2cnc(N)nc2)nc(N2CCOCC2)n1.N#Cc1cccc(Nc2cc(-c3cnc(N)nc3)nc(N3CCOCC3)n2)c1.Nc1ccc(-c2cc(-c3nn[nH]n3)nc(N3CCOCC3)n2)cn1.Nc1ccc(-c2cc(Nc3ccc(F)cc3)nc(N3CCOCC3)n2)cn1
InChIInChI=1S/C19H19FN6O.C19H18N8O.2C19H21N7O2.C14H15N9O/c20-14-2-4-15(5-3-14)23-18-11-16(13-1-6-17(21)22-12-13)24-19(25-18)26-7-9-27-10-8-26;20-10-13-2-1-3-15(8-13)24-17-9-16(14-11-22-18(21)23-12-14)25-19(26-17)27-4-6-28-7-5-27;1-27-15-4-2-3-14(9-15)23-17-10-16(13-11-21-18(20)22-12-13)24-19(25-17)26-5-7-28-8-6-26;1-27-16-5-3-2-4-14(16)23-17-10-15(13-11-21-18(20)22-12-13)24-19(25-17)26-6-8-28-9-7-26;15-12-2-1-9(8-16-12)10-7-11(13-19-21-22-20-13)18-14(17-10)23-3-5-24-6-4-23/h1-6,11-12H,7-10H2,(H2,21,22)(H,23,24,25);1-3,8-9,11-12H,4-7H2,(H2,21,22,23)(H,24,25,26);2-4,9-12H,5-8H2,1H3,(H2,20,21,22)(H,23,24,25);2-5,10-12H,6-9H2,1H3,(H2,20,21,22)(H,23,24,25);1-2,7-8H,3-6H2,(H2,15,16)(H,19,20,21,22)
InChIKeyJMHHTSIQIAGUQT-UHFFFAOYSA-N
MW1824.99 g/mol
LogP9.15
Rot. Bonds21

About 6-(6-amino-3-pyridinyl)-N-(4-fluorophenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(2-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(3-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;3-[[6-(2-aminopyrimidin-5-yl)-2-morpholin-4-ylpyrimidin-4-yl]amino]benzonitrile;5-[2-morpholin-4-yl-6-(2H-tetrazol-5-yl)pyrimidin-4-yl]pyridin-2-amine

6-(6-amino-3-pyridinyl)-N-(4-fluorophenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(2-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(3-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;3-[[6-(2-aminopyrimidin-5-yl)-2-morpholin-4-ylpyrimidin-4-yl]amino]benzonitrile;5-[2-morpholin-4-yl-6-(2H-tetrazol-5-yl)pyrimidin-4-yl]pyridin-2-amine (PubChem CID 158958316) has the molecular formula C90H94FN37O7 and a molecular weight of 1824.99 g/mol. Its IUPAC name is 6-(6-amino-3-pyridinyl)-N-(4-fluorophenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(2-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(3-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;3-[[6-(2-aminopyrimidin-5-yl)-2-morpholin-4-ylpyrimidin-4-yl]amino]benzonitrile;5-[2-morpholin-4-yl-6-(2H-tetrazol-5-yl)pyrimidin-4-yl]pyridin-2-amine.

Molecular Properties

Compound Name6-(6-amino-3-pyridinyl)-N-(4-fluorophenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(2-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(3-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;3-[[6-(2-aminopyrimidin-5-yl)-2-morpholin-4-ylpyrimidin-4-yl]amino]benzonitrile;5-[2-morpholin-4-yl-6-(2H-tetrazol-5-yl)pyrimidin-4-yl]pyridin-2-amine
PubChem CID158958316
Molecular FormulaC90H94FN37O7
Molecular Weight1824.99 g/mol
Exact Mass1823.81
IUPAC Name6-(6-amino-3-pyridinyl)-N-(4-fluorophenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(2-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(3-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;3-[[6-(2-aminopyrimidin-5-yl)-2-morpholin-4-ylpyrimidin-4-yl]amino]benzonitrile;5-[2-morpholin-4-yl-6-(2H-tetrazol-5-yl)pyrimidin-4-yl]pyridin-2-amine
SMILESCOc1cccc(Nc2cc(-c3cnc(N)nc3)nc(N3CCOCC3)n2)c1.COc1ccccc1Nc1cc(-c2cnc(N)nc2)nc(N2CCOCC2)n1.N#Cc1cccc(Nc2cc(-c3cnc(N)nc3)nc(N3CCOCC3)n2)c1.Nc1ccc(-c2cc(-c3nn[nH]n3)nc(N3CCOCC3)n2)cn1.Nc1ccc(-c2cc(Nc3ccc(F)cc3)nc(N3CCOCC3)n2)cn1
InChIInChI=1S/C19H19FN6O.C19H18N8O.2C19H21N7O2.C14H15N9O/c20-14-2-4-15(5-3-14)23-18-11-16(13-1-6-17(21)22-12-13)24-19(25-18)26-7-9-27-10-8-26;20-10-13-2-1-3-15(8-13)24-17-9-16(14-11-22-18(21)23-12-14)25-19(26-17)27-4-6-28-7-5-27;1-27-15-4-2-3-14(9-15)23-17-10-16(13-11-21-18(20)22-12-13)24-19(25-17)26-5-7-28-8-6-26;1-27-16-5-3-2-4-14(16)23-17-10-15(13-11-21-18(20)22-12-13)24-19(25-17)26-6-8-28-9-7-26;15-12-2-1-9(8-16-12)10-7-11(13-19-21-22-20-13)18-14(17-10)23-3-5-24-6-4-23/h1-6,11-12H,7-10H2,(H2,21,22)(H,23,24,25);1-3,8-9,11-12H,4-7H2,(H2,21,22,23)(H,24,25,26);2-4,9-12H,5-8H2,1H3,(H2,20,21,22)(H,23,24,25);2-5,10-12H,6-9H2,1H3,(H2,20,21,22)(H,23,24,25);1-2,7-8H,3-6H2,(H2,15,16)(H,19,20,21,22)
InChIKeyJMHHTSIQIAGUQT-UHFFFAOYSA-N
XLogP9.15
TPSA569.30 Ų
H-Bond Donors10
H-Bond Acceptors43
Rotatable Bonds21
Heavy Atoms135
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001824.99
LogP ≤ 59.15
H-Bond Donors ≤ 510
H-Bond Acceptors ≤ 1043

Analyze 6-(6-amino-3-pyridinyl)-N-(4-fluorophenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(2-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(3-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;3-[[6-(2-aminopyrimidin-5-yl)-2-morpholin-4-ylpyrimidin-4-yl]amino]benzonitrile;5-[2-morpholin-4-yl-6-(2H-tetrazol-5-yl)pyrimidin-4-yl]pyridin-2-amine with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

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Related Compounds

4-[4-[(2-methoxyethylamino)methyl]-3-phenylpyrazol-1-yl]-N-[2-methoxy-5-methyl-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidin-2-amine
CID 172462410
4-(3-fluoro-5-morpholin-4-ylphenyl)-N-[4-[3-(6-methoxy-2-pyridinyl)-1,2,4-triazol-1-yl]phenyl]pyrimidin-2-amine
CID 25222485
3-[6-[2-[6-[3-(2,6-difluoro-3-methoxyanilino)pyrazin-2-yl]pyrimidin-4-yl]-2-[5-(morpholin-4-ylmethyl)-2-pyridinyl]hydrazinyl]pyrimidin-4-yl]-N-(2,6-difluoro-3-methoxyphenyl)pyrazin-2-amine
CID 67174048
3-[6-[[[6-[3-(2,6-difluoro-3-methoxyanilino)pyrazin-2-yl]pyrimidin-4-yl]-[4-(morpholin-4-ylmethyl)-2-pyridinyl]amino]-[5-(morpholin-4-ylmethyl)-2-pyridinyl]amino]pyrimidin-4-yl]-N-(2,6-difluoro-3-methoxyphenyl)pyrazin-2-amine
CID 87609086
4-[8-[4-[(5-fluoro-2,6-dimethylpyrimidin-4-yl)amino]cyclohexyl]oxyquinoxalin-6-yl]-N-[4-(7-morpholin-4-ylquinoxalin-5-yl)oxycyclohexyl]-N-[5-(2H-tetrazol-5-yl)pyrimidin-2-yl]morpholin-2-amine
CID 156254595
6-[5-amino-3-(2-methoxy-4-morpholin-4-ylanilino)-1,2,4-triazol-1-yl]pyridine-3-carbonitrile;3-N-(2-methoxy-4-morpholin-4-ylphenyl)-1-[6-(trifluoromethyl)-2-pyridinyl]-1,2,4-triazole-3,5-diamine;3-N-(4-morpholin-4-ylphenyl)-1-[6-(trifluoromethyl)-2-pyridinyl]-1,2,4-triazole-3,5-diamine
CID 159277638
6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-N-[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-amine;4-[[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]amino]benzonitrile;5-[[6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-ylpyrimidin-4-yl]amino]pyridine-2-carbonitrile;6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-[4-(2H-tetrazol-5-yl)phenyl]pyrimidin-4-amine;6-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-2-morpholin-4-yl-N-[6-(2H-tetrazol-5-yl)-3-pyridinyl]pyrimidin-4-amine
CID 160302597
N-[3-[difluoro-[5-fluoro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]methyl]phenyl]prop-2-enamide;N-[3-[difluoro-[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]-5-methoxypyrimidin-4-yl]methyl]phenyl]prop-2-enamide;N-[3-[difluoro-[5-fluoro-2-[[6-(4-methylpiperazin-1-yl)-3-pyridinyl]amino]pyrimidin-4-yl]methyl]phenyl]prop-2-enamide;N-[3-[difluoro-[5-methoxy-2-[[6-(4-methylpiperazin-1-yl)-3-pyridinyl]amino]pyrimidin-4-yl]methyl]phenyl]prop-2-enamide
CID 161534006
CID 163574005
CID 163574005
CID 163992355
CID 163992355
6-[(3R)-3-(5-fluoro-3-pyridinyl)-1,2-oxazolidin-2-yl]-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidin-4-amine
CID 166135356
6-[(3S)-3-(5-fluoro-3-pyridinyl)-1,2-oxazolidin-2-yl]-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidin-4-amine
CID 166135432

Frequently Asked Questions

What is the IUPAC name of 6-(6-amino-3-pyridinyl)-N-(4-fluorophenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(2-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(3-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;3-[[6-(2-aminopyrimidin-5-yl)-2-morpholin-4-ylpyrimidin-4-yl]amino]benzonitrile;5-[2-morpholin-4-yl-6-(2H-tetrazol-5-yl)pyrimidin-4-yl]pyridin-2-amine?
The IUPAC name of 6-(6-amino-3-pyridinyl)-N-(4-fluorophenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(2-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(3-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;3-[[6-(2-aminopyrimidin-5-yl)-2-morpholin-4-ylpyrimidin-4-yl]amino]benzonitrile;5-[2-morpholin-4-yl-6-(2H-tetrazol-5-yl)pyrimidin-4-yl]pyridin-2-amine (CID 158958316) is 6-(6-amino-3-pyridinyl)-N-(4-fluorophenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(2-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(3-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;3-[[6-(2-aminopyrimidin-5-yl)-2-morpholin-4-ylpyrimidin-4-yl]amino]benzonitrile;5-[2-morpholin-4-yl-6-(2H-tetrazol-5-yl)pyrimidin-4-yl]pyridin-2-amine.
What is the SMILES notation for 6-(6-amino-3-pyridinyl)-N-(4-fluorophenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(2-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(3-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;3-[[6-(2-aminopyrimidin-5-yl)-2-morpholin-4-ylpyrimidin-4-yl]amino]benzonitrile;5-[2-morpholin-4-yl-6-(2H-tetrazol-5-yl)pyrimidin-4-yl]pyridin-2-amine?
The canonical SMILES for 6-(6-amino-3-pyridinyl)-N-(4-fluorophenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(2-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(3-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;3-[[6-(2-aminopyrimidin-5-yl)-2-morpholin-4-ylpyrimidin-4-yl]amino]benzonitrile;5-[2-morpholin-4-yl-6-(2H-tetrazol-5-yl)pyrimidin-4-yl]pyridin-2-amine is COc1cccc(Nc2cc(-c3cnc(N)nc3)nc(N3CCOCC3)n2)c1.COc1ccccc1Nc1cc(-c2cnc(N)nc2)nc(N2CCOCC2)n1.N#Cc1cccc(Nc2cc(-c3cnc(N)nc3)nc(N3CCOCC3)n2)c1.Nc1ccc(-c2cc(-c3nn[nH]n3)nc(N3CCOCC3)n2)cn1.Nc1ccc(-c2cc(Nc3ccc(F)cc3)nc(N3CCOCC3)n2)cn1.
What is the InChIKey of 6-(6-amino-3-pyridinyl)-N-(4-fluorophenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(2-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(3-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;3-[[6-(2-aminopyrimidin-5-yl)-2-morpholin-4-ylpyrimidin-4-yl]amino]benzonitrile;5-[2-morpholin-4-yl-6-(2H-tetrazol-5-yl)pyrimidin-4-yl]pyridin-2-amine?
The InChIKey is JMHHTSIQIAGUQT-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H19FN6O.C19H18N8O.2C19H21N7O2.C14H15N9O/c20-14-2-4-15(5-3-14)23-18-11-16(13-1-6-17(21)22-12-13)24-19(25-18)26-7-9-27-10-8-26;20-10-13-2-1-3-15(8-13)24-17-9-16(14-11-22-18(21)23-12-14)25-19(26-17)27-4-6-28-7-5-27;1-27-15-4-2-3-14(9-15)23-17-10-16(13-11-21-18(20)22-12-13)24-19(25-17)26-5-7-28-8-6-26;1-27-16-5-3-2-4-14(16)23-17-10-15(13-11-21-18(20)22-12-13)24-19(25-17)26-6-8-28-9-7-26;15-12-2-1-9(8-16-12)10-7-11(13-19-21-22-20-13)18-14(17-10)23-3-5-24-6-4-23/h1-6,11-12H,7-10H2,(H2,21,22)(H,23,24,25);1-3,8-9,11-12H,4-7H2,(H2,21,22,23)(H,24,25,26);2-4,9-12H,5-8H2,1H3,(H2,20,21,22)(H,23,24,25);2-5,10-12H,6-9H2,1H3,(H2,20,21,22)(H,23,24,25);1-2,7-8H,3-6H2,(H2,15,16)(H,19,20,21,22).
What are the key properties of 6-(6-amino-3-pyridinyl)-N-(4-fluorophenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(2-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(3-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;3-[[6-(2-aminopyrimidin-5-yl)-2-morpholin-4-ylpyrimidin-4-yl]amino]benzonitrile;5-[2-morpholin-4-yl-6-(2H-tetrazol-5-yl)pyrimidin-4-yl]pyridin-2-amine?
6-(6-amino-3-pyridinyl)-N-(4-fluorophenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(2-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(3-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;3-[[6-(2-aminopyrimidin-5-yl)-2-morpholin-4-ylpyrimidin-4-yl]amino]benzonitrile;5-[2-morpholin-4-yl-6-(2H-tetrazol-5-yl)pyrimidin-4-yl]pyridin-2-amine has a molecular weight of 1824.99 g/mol, XLogP of 9.15, 21 rotatable bonds, 10 hydrogen bond donors, and 43 hydrogen bond acceptors.
Where does this data come from?
All data for 6-(6-amino-3-pyridinyl)-N-(4-fluorophenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(2-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;6-(2-aminopyrimidin-5-yl)-N-(3-methoxyphenyl)-2-morpholin-4-ylpyrimidin-4-amine;3-[[6-(2-aminopyrimidin-5-yl)-2-morpholin-4-ylpyrimidin-4-yl]amino]benzonitrile;5-[2-morpholin-4-yl-6-(2H-tetrazol-5-yl)pyrimidin-4-yl]pyridin-2-amine is sourced from PubChem (CID 158958316), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).