1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(2-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(3-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(4-fluorophenyl)imidazolidin-2-one

C78H67Cl2F6N21O6S3 — CID 158971458

IUPAC1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(2-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(3-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(4-fluorophenyl)imidazolidin-2-one
SMILESNc1nccc(-c2nc(N3CCOCC3)sc2-c2cccc(N3CCN(c4ccc(F)c(Cl)c4)C3=O)c2F)n1.Nc1nccc(-c2nc(N3CCOCC3)sc2-c2cccc(N3CCN(c4ccc(F)cc4)C3=O)c2F)n1.Nc1nccc(-c2nc(N3CCOCC3)sc2-c2cccc(N3CCN(c4ccc(F)cc4Cl)C3=O)c2F)n1
InChIInChI=1S/2C26H22ClF2N7O2S.C26H23F2N7O2S/c27-17-14-15(28)4-5-19(17)35-8-9-36(26(35)37)20-3-1-2-16(21(20)29)23-22(18-6-7-31-24(30)32-18)33-25(39-23)34-10-12-38-13-11-34;27-17-14-15(4-5-18(17)28)35-8-9-36(26(35)37)20-3-1-2-16(21(20)29)23-22(19-6-7-31-24(30)32-19)33-25(39-23)34-10-12-38-13-11-34;27-16-4-6-17(7-5-16)34-10-11-35(26(34)36)20-3-1-2-18(21(20)28)23-22(19-8-9-30-24(29)31-19)32-25(38-23)33-12-14-37-15-13-33/h2*1-7,14H,8-13H2,(H2,30,31,32);1-9H,10-15H2,(H2,29,30,31)
InChIKeyJNWISOKFZLZWPE-UHFFFAOYSA-N
MW1675.63 g/mol
LogP14.54
Rot. Bonds15

About 1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(2-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(3-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(4-fluorophenyl)imidazolidin-2-one

1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(2-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(3-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(4-fluorophenyl)imidazolidin-2-one (PubChem CID 158971458) has the molecular formula C78H67Cl2F6N21O6S3 and a molecular weight of 1675.63 g/mol. Its IUPAC name is 1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(2-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(3-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(4-fluorophenyl)imidazolidin-2-one.

Molecular Properties

Compound Name1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(2-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(3-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(4-fluorophenyl)imidazolidin-2-one
PubChem CID158971458
Molecular FormulaC78H67Cl2F6N21O6S3
Molecular Weight1675.63 g/mol
Exact Mass1673.40
IUPAC Name1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(2-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(3-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(4-fluorophenyl)imidazolidin-2-one
SMILESNc1nccc(-c2nc(N3CCOCC3)sc2-c2cccc(N3CCN(c4ccc(F)c(Cl)c4)C3=O)c2F)n1.Nc1nccc(-c2nc(N3CCOCC3)sc2-c2cccc(N3CCN(c4ccc(F)cc4)C3=O)c2F)n1.Nc1nccc(-c2nc(N3CCOCC3)sc2-c2cccc(N3CCN(c4ccc(F)cc4Cl)C3=O)c2F)n1
InChIInChI=1S/2C26H22ClF2N7O2S.C26H23F2N7O2S/c27-17-14-15(28)4-5-19(17)35-8-9-36(26(35)37)20-3-1-2-16(21(20)29)23-22(18-6-7-31-24(30)32-18)33-25(39-23)34-10-12-38-13-11-34;27-17-14-15(4-5-18(17)28)35-8-9-36(26(35)37)20-3-1-2-16(21(20)29)23-22(19-6-7-31-24(30)32-19)33-25(39-23)34-10-12-38-13-11-34;27-16-4-6-17(7-5-16)34-10-11-35(26(34)36)20-3-1-2-18(21(20)28)23-22(19-8-9-30-24(29)31-19)32-25(38-23)33-12-14-37-15-13-33/h2*1-7,14H,8-13H2,(H2,30,31,32);1-9H,10-15H2,(H2,29,30,31)
InChIKeyJNWISOKFZLZWPE-UHFFFAOYSA-N
XLogP14.54
TPSA302.13 Ų
H-Bond Donors3
H-Bond Acceptors24
Rotatable Bonds15
Heavy Atoms116
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001675.63
LogP ≤ 514.54
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 1024

Analyze 1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(2-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(3-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(4-fluorophenyl)imidazolidin-2-one with MolForge

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Related Compounds

1-[3-[4-(2-Aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]phenyl]-3-(3-chloro-4-fluorophenyl)imidazolidin-2-one
CID 90326659
1-[3-[4-(2-Aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]phenyl]-3-(2-chloro-4-fluorophenyl)imidazolidin-2-one
CID 90326665
1-[3-[4-(2-Aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(2-chloro-4-fluorophenyl)imidazolidin-2-one
CID 90326676
1-[3-[4-(2-Aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(3-chloro-4-fluorophenyl)imidazolidin-2-one
CID 90326677
1-[5-[4-(2-Aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(3-chloro-4-fluorophenyl)imidazolidin-2-one
CID 90326692
1-[5-[4-(2-Aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(2-chloro-4-fluorophenyl)imidazolidin-2-one
CID 90326693
1-[3-[2-[2-[2-Amino-6-[5-[3-[3-(4-chlorophenyl)-2-oxoimidazolidin-1-yl]-2-fluorophenyl]-2-morpholin-4-yl-1,3-thiazol-4-yl]pyrimidin-4-yl]morpholin-4-yl]-4-(2-aminopyrimidin-4-yl)-1,3-thiazol-5-yl]-2-fluorophenyl]-3-[4-(trifluoromethyl)phenyl]imidazolidin-2-one
CID 123227880
1-[3-[2-[2-[2-Amino-6-[5-[3-[3-(3-chloro-4-fluorophenyl)-2-oxoimidazolidin-1-yl]phenyl]-2-morpholin-4-yl-1,3-thiazol-4-yl]pyrimidin-4-yl]morpholin-4-yl]-4-(2-aminopyrimidin-4-yl)-1,3-thiazol-5-yl]phenyl]-3-(4-fluorophenyl)imidazolidin-2-one
CID 123380368
1-[5-[2-[2-[2-Amino-6-[5-[3-[3-(3-chloro-4-fluorophenyl)-2-oxoimidazolidin-1-yl]-4-fluorophenyl]-2-morpholin-4-yl-1,3-thiazol-4-yl]pyrimidin-4-yl]morpholin-4-yl]-4-(2-aminopyrimidin-4-yl)-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(4-fluorophenyl)imidazolidin-2-one
CID 123513248
1-[3-[2-[2-[2-Amino-6-[5-[3-[3-(3-chloro-4-fluorophenyl)-2-oxoimidazolidin-1-yl]-2-fluorophenyl]-2-morpholin-4-yl-1,3-thiazol-4-yl]pyrimidin-4-yl]morpholin-4-yl]-4-(2-aminopyrimidin-4-yl)-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(4-fluorophenyl)imidazolidin-2-one
CID 123821179
1-[5-[4-(2-Aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(4-chlorophenyl)imidazolidin-2-one;1-[5-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(2,4-difluorophenyl)urea;1-[5-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-[4-(trifluoromethyl)phenyl]imidazolidin-2-one
CID 157966788
5-chloro-2-propan-2-ylpyridine;N',N'-dimethyl-N-(4-propan-2-yl-1,3-thiazol-2-yl)ethane-1,2-diamine;5-fluoro-2-propan-2-ylpyridine;methane;N-(2-methoxyethyl)-4-propan-2-yl-1,3-thiazol-2-amine;N-(2-methyl-4-propan-2-ylphenyl)acetamide;2-methyl-5-propan-2-ylpyridine;2-methyl-6-propan-2-ylpyridine;4-methyl-2-propan-2-ylpyridine;bis(5-methyl-2-propan-2-ylpyridine);N-(2-morpholin-4-ylethyl)-4-propan-2-yl-1,3-thiazol-2-amine;N-(2-piperidin-1-ylethyl)-4-propan-2-yl-1,3-thiazol-2-amine;3-propan-2-ylaniline;4-propan-2-ylaniline;N-(4-propan-2-yl-1,3-thiazol-2-yl)acetamide;2-propan-2-yl-5-(trifluoromethyl)pyridine
CID 158030848

Frequently Asked Questions

What is the IUPAC name of 1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(2-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(3-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(4-fluorophenyl)imidazolidin-2-one?
The IUPAC name of 1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(2-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(3-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(4-fluorophenyl)imidazolidin-2-one (CID 158971458) is 1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(2-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(3-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(4-fluorophenyl)imidazolidin-2-one.
What is the SMILES notation for 1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(2-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(3-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(4-fluorophenyl)imidazolidin-2-one?
The canonical SMILES for 1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(2-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(3-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(4-fluorophenyl)imidazolidin-2-one is Nc1nccc(-c2nc(N3CCOCC3)sc2-c2cccc(N3CCN(c4ccc(F)c(Cl)c4)C3=O)c2F)n1.Nc1nccc(-c2nc(N3CCOCC3)sc2-c2cccc(N3CCN(c4ccc(F)cc4)C3=O)c2F)n1.Nc1nccc(-c2nc(N3CCOCC3)sc2-c2cccc(N3CCN(c4ccc(F)cc4Cl)C3=O)c2F)n1.
What is the InChIKey of 1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(2-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(3-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(4-fluorophenyl)imidazolidin-2-one?
The InChIKey is JNWISOKFZLZWPE-UHFFFAOYSA-N. The full InChI is InChI=1S/2C26H22ClF2N7O2S.C26H23F2N7O2S/c27-17-14-15(28)4-5-19(17)35-8-9-36(26(35)37)20-3-1-2-16(21(20)29)23-22(18-6-7-31-24(30)32-18)33-25(39-23)34-10-12-38-13-11-34;27-17-14-15(4-5-18(17)28)35-8-9-36(26(35)37)20-3-1-2-16(21(20)29)23-22(19-6-7-31-24(30)32-19)33-25(39-23)34-10-12-38-13-11-34;27-16-4-6-17(7-5-16)34-10-11-35(26(34)36)20-3-1-2-18(21(20)28)23-22(19-8-9-30-24(29)31-19)32-25(38-23)33-12-14-37-15-13-33/h2*1-7,14H,8-13H2,(H2,30,31,32);1-9H,10-15H2,(H2,29,30,31).
What are the key properties of 1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(2-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(3-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(4-fluorophenyl)imidazolidin-2-one?
1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(2-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(3-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(4-fluorophenyl)imidazolidin-2-one has a molecular weight of 1675.63 g/mol, XLogP of 14.54, 15 rotatable bonds, 3 hydrogen bond donors, and 24 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(2-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(3-chloro-4-fluorophenyl)imidazolidin-2-one;1-[3-[4-(2-aminopyrimidin-4-yl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-2-fluorophenyl]-3-(4-fluorophenyl)imidazolidin-2-one is sourced from PubChem (CID 158971458), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).