2-[2-chloro-6-fluoro-3-((18F)fluoromethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-[2,6-difluoro-3-(2-(18F)fluoroethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-(3,5-difluoro-4-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(2-(18F)fluoroethoxy)imidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-(2-(18F)fluoroethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-((18F)fluoromethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine

C120H105ClF10N16O19 — CID 158982183

About 2-[2-chloro-6-fluoro-3-((18F)fluoromethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-[2,6-difluoro-3-(2-(18F)fluoroethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-(3,5-difluoro-4-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(2-(18F)fluoroethoxy)imidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-(2-(18F)fluoroethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-((18F)fluoromethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine

2-[2-chloro-6-fluoro-3-((18F)fluoromethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-[2,6-difluoro-3-(2-(18F)fluoroethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-(3,5-difluoro-4-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(2-(18F)fluoroethoxy)imidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-(2-(18F)fluoroethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-((18F)fluoromethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine (PubChem CID 158982183) has the molecular formula C120H105ClF10N16O19 and a molecular weight of 2295.70 g/mol. Its IUPAC name is 2-[2-chloro-6-fluoro-3-((18F)fluoromethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-[2,6-difluoro-3-(2-(18F)fluoroethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-(3,5-difluoro-4-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(2-(18F)fluoroethoxy)imidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-(2-(18F)fluoroethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-((18F)fluoromethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine.

Molecular Properties

• Compound Name: 2-[2-chloro-6-fluoro-3-((18F)fluoromethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-[2,6-difluoro-3-(2-(18F)fluoroethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-(3,5-difluoro-4-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(2-(18F)fluoroethoxy)imidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-(2-(18F)fluoroethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-((18F)fluoromethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine
• PubChem CID: 158982183
• Molecular Formula: C120H105ClF10N16O19
• Molecular Weight: 2295.70 g/mol
• Exact Mass: 2293.74
• IUPAC Name: 2-[2-chloro-6-fluoro-3-((18F)fluoromethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-[2,6-difluoro-3-(2-(18F)fluoroethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-(3,5-difluoro-4-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(2-(18F)fluoroethoxy)imidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-(2-(18F)fluoroethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-((18F)fluoromethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine
• SMILES: COc1cccc2nc(-c3c(C)cc(OCC[18F])cc3C)c(Nc3ccc4c(c3)OCCO4)n12.COc1cccc2nc(-c3c(C)cc(OC[18F])cc3C)c(Nc3ccc4c(c3)OCCO4)n12.COc1cccc2nc(-c3c(F)ccc(OCC[18F])c3F)c(Nc3ccc4c(c3)OCCO4)n12.COc1cccc2nc(-c3c(F)ccc(OC[18F])c3Cl)c(Nc3ccc4c(c3)OCCO4)n12.Fc1cncc(F)c1-c1nc2cccc(OCC[18F])n2c1Nc1ccc2c(c1)OCCO2
• InChI: InChI=1S/C26H26FN3O4.C25H24FN3O4.C24H20F3N3O4.C23H18ClF2N3O4.C22H17F3N4O3/c1-16-13-19(32-10-9-27)14-17(2)24(16)25-26(30-22(29-25)5-4-6-23(30)31-3)28-18-7-8-20-21(15-18)34-12-11-33-20;1-15-11-18(33-14-26)12-16(2)23(15)24-25(29-21(28-24)5-4-6-22(29)30-3)27-17-7-8-19-20(13-17)32-10-9-31-19;1-31-20-4-2-3-19-29-23(21-15(26)6-8-17(22(21)27)32-10-9-25)24(30(19)20)28-14-5-7-16-18(13-14)34-12-11-33-16;1-30-19-4-2-3-18-28-22(20-14(26)6-8-16(21(20)24)33-12-25)23(29(18)19)27-13-5-7-15-17(11-13)32-10-9-31-15;23-6-7-32-19-3-1-2-18-28-21(20-14(24)11-26-12-15(20)25)22(29(18)19)27-13-4-5-16-17(10-13)31-9-8-30-16/h4-8,13-15,28H,9-12H2,1-3H3;4-8,11-13,27H,9-10,14H2,1-3H3;2-8,13,28H,9-12H2,1H3;2-8,11,27H,9-10,12H2,1H3;1-5,10-12,27H,6-9H2/i27-1;26-1;2*25-1;23-1
• InChIKey: JPDDZYNGQYGMSF-WQNPBHBXSA-N
• XLogP: 26.25
• TPSA: 334.91 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 35
• Rotatable Bonds: 32
• Heavy Atoms: 166
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2295.70
LogP ≤ 5	26.25
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	35

Frequently Asked Questions

What is the IUPAC name of 2-[2-chloro-6-fluoro-3-((18F)fluoromethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-[2,6-difluoro-3-(2-(18F)fluoroethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-(3,5-difluoro-4-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(2-(18F)fluoroethoxy)imidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-(2-(18F)fluoroethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-((18F)fluoromethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine?

The IUPAC name of 2-[2-chloro-6-fluoro-3-((18F)fluoromethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-[2,6-difluoro-3-(2-(18F)fluoroethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-(3,5-difluoro-4-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(2-(18F)fluoroethoxy)imidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-(2-(18F)fluoroethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-((18F)fluoromethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine (CID 158982183) is 2-[2-chloro-6-fluoro-3-((18F)fluoromethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-[2,6-difluoro-3-(2-(18F)fluoroethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-(3,5-difluoro-4-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(2-(18F)fluoroethoxy)imidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-(2-(18F)fluoroethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-((18F)fluoromethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine.

What is the SMILES notation for 2-[2-chloro-6-fluoro-3-((18F)fluoromethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-[2,6-difluoro-3-(2-(18F)fluoroethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-(3,5-difluoro-4-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(2-(18F)fluoroethoxy)imidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-(2-(18F)fluoroethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-((18F)fluoromethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine?

The canonical SMILES for 2-[2-chloro-6-fluoro-3-((18F)fluoromethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-[2,6-difluoro-3-(2-(18F)fluoroethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-(3,5-difluoro-4-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(2-(18F)fluoroethoxy)imidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-(2-(18F)fluoroethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-((18F)fluoromethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine is COc1cccc2nc(-c3c(C)cc(OCC[18F])cc3C)c(Nc3ccc4c(c3)OCCO4)n12.COc1cccc2nc(-c3c(C)cc(OC[18F])cc3C)c(Nc3ccc4c(c3)OCCO4)n12.COc1cccc2nc(-c3c(F)ccc(OCC[18F])c3F)c(Nc3ccc4c(c3)OCCO4)n12.COc1cccc2nc(-c3c(F)ccc(OC[18F])c3Cl)c(Nc3ccc4c(c3)OCCO4)n12.Fc1cncc(F)c1-c1nc2cccc(OCC[18F])n2c1Nc1ccc2c(c1)OCCO2.

What is the InChIKey of 2-[2-chloro-6-fluoro-3-((18F)fluoromethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-[2,6-difluoro-3-(2-(18F)fluoroethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-(3,5-difluoro-4-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(2-(18F)fluoroethoxy)imidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-(2-(18F)fluoroethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-((18F)fluoromethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine?

The InChIKey is JPDDZYNGQYGMSF-WQNPBHBXSA-N. The full InChI is InChI=1S/C26H26FN3O4.C25H24FN3O4.C24H20F3N3O4.C23H18ClF2N3O4.C22H17F3N4O3/c1-16-13-19(32-10-9-27)14-17(2)24(16)25-26(30-22(29-25)5-4-6-23(30)31-3)28-18-7-8-20-21(15-18)34-12-11-33-20;1-15-11-18(33-14-26)12-16(2)23(15)24-25(29-21(28-24)5-4-6-22(29)30-3)27-17-7-8-19-20(13-17)32-10-9-31-19;1-31-20-4-2-3-19-29-23(21-15(26)6-8-17(22(21)27)32-10-9-25)24(30(19)20)28-14-5-7-16-18(13-14)34-12-11-33-16;1-30-19-4-2-3-18-28-22(20-14(26)6-8-16(21(20)24)33-12-25)23(29(18)19)27-13-5-7-15-17(11-13)32-10-9-31-15;23-6-7-32-19-3-1-2-18-28-21(20-14(24)11-26-12-15(20)25)22(29(18)19)27-13-4-5-16-17(10-13)31-9-8-30-16/h4-8,13-15,28H,9-12H2,1-3H3;4-8,11-13,27H,9-10,14H2,1-3H3;2-8,13,28H,9-12H2,1H3;2-8,11,27H,9-10,12H2,1H3;1-5,10-12,27H,6-9H2/i27-1;26-1;2*25-1;23-1.

What are the key properties of 2-[2-chloro-6-fluoro-3-((18F)fluoromethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-[2,6-difluoro-3-(2-(18F)fluoroethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-(3,5-difluoro-4-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(2-(18F)fluoroethoxy)imidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-(2-(18F)fluoroethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-((18F)fluoromethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine?

2-[2-chloro-6-fluoro-3-((18F)fluoromethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-[2,6-difluoro-3-(2-(18F)fluoroethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-(3,5-difluoro-4-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(2-(18F)fluoroethoxy)imidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-(2-(18F)fluoroethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-((18F)fluoromethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine has a molecular weight of 2295.70 g/mol, XLogP of 26.25, 32 rotatable bonds, 5 hydrogen bond donors, and 35 hydrogen bond acceptors.

Where does this data come from?

All data for 2-[2-chloro-6-fluoro-3-((18F)fluoromethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-[2,6-difluoro-3-(2-(18F)fluoroethoxy)phenyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyimidazo[1,2-a]pyridin-3-amine;2-(3,5-difluoro-4-pyridinyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(2-(18F)fluoroethoxy)imidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-(2-(18F)fluoroethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-((18F)fluoromethoxy)-2,6-dimethylphenyl]-5-methoxyimidazo[1,2-a]pyridin-3-amine is sourced from PubChem (CID 158982183), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).