5-amino-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;1-[4-(2-aminoethoxy)-3-methoxyphenyl]-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;2-[2-bromo-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetic acid;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-fluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-5-hydroxypentan-1-one;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4,5-dihydroxypentan-1-one;4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxy-1-[3-methoxy-4-(methylsulfonylmethoxy)phenyl]pentan-1-one;2-[2-fluoro-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide

C190H196BrF15N10O39S — CID 159025533

IUPAC5-amino-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;1-[4-(2-aminoethoxy)-3-methoxyphenyl]-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;2-[2-bromo-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetic acid;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-fluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-5-hydroxypentan-1-one;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4,5-dihydroxypentan-1-one;4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxy-1-[3-methoxy-4-(methylsulfonylmethoxy)phenyl]pentan-1-one;2-[2-fluoro-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide
SMILESCOc1cc(C(=O)CCC(C)(O)c2ccc(OC)c(-c3ccc(F)c(C)c3)n2)ccc1OCCN.COc1cc(C(=O)CCC(C)(O)c2ccc(OC)c(-c3ccc(F)c(C)c3)n2)ccc1OCS(C)(=O)=O.COc1cc(C(=O)CCC(F)(CO)c2ccc(OC)c(-c3ccc(F)c(C)c3)n2)ccc1OC1CC1.COc1cc(C(=O)CCC(O)(CN)c2ccc(OC)c(-c3ccc(F)c(C)c3)n2)ccc1OC1CC1.COc1cc(C(=O)CCC(O)(CO)c2ccc(OC)c(-c3ccc(F)c(C)c3)n2)ccc1OC1CC1.COc1ccc(C(O)(CCC(=O)c2ccc(OCC(=O)O)c(Br)c2)C(F)(F)F)nc1-c1ccc(F)c(C)c1.COc1ccc(C(O)(CCC(=O)c2ccc(OCC(N)=O)c(F)c2)C(F)(F)F)nc1-c1ccc(F)c(C)c1
InChIInChI=1S/C28H29F2NO5.C28H31FN2O5.C28H30FNO6.C27H31FN2O5.C27H30FNO7S.C26H22BrF4NO6.C26H23F5N2O5/c1-17-14-19(4-8-21(17)29)27-24(34-2)10-11-26(31-27)28(30,16-32)13-12-22(33)18-5-9-23(25(15-18)35-3)36-20-6-7-20;1-17-14-19(4-8-21(17)29)27-24(34-2)10-11-26(31-27)28(33,16-30)13-12-22(32)18-5-9-23(25(15-18)35-3)36-20-6-7-20;1-17-14-19(4-8-21(17)29)27-24(34-2)10-11-26(30-27)28(33,16-31)13-12-22(32)18-5-9-23(25(15-18)35-3)36-20-6-7-20;1-17-15-19(5-7-20(17)28)26-23(33-3)9-10-25(30-26)27(2,32)12-11-21(31)18-6-8-22(35-14-13-29)24(16-18)34-4;1-17-14-19(6-8-20(17)28)26-23(34-3)10-11-25(29-26)27(2,31)13-12-21(30)18-7-9-22(24(15-18)35-4)36-16-37(5,32)33;1-14-11-16(3-5-18(14)28)24-21(37-2)7-8-22(32-24)25(36,26(29,30)31)10-9-19(33)15-4-6-20(17(27)12-15)38-13-23(34)35;1-14-11-16(3-5-17(14)27)24-21(37-2)7-8-22(33-24)25(36,26(29,30)31)10-9-19(34)15-4-6-20(18(28)12-15)38-13-23(32)35/h4-5,8-11,14-15,20,32H,6-7,12-13,16H2,1-3H3;4-5,8-11,14-15,20,33H,6-7,12-13,16,30H2,1-3H3;4-5,8-11,14-15,20,31,33H,6-7,12-13,16H2,1-3H3;5-10,15-16,32H,11-14,29H2,1-4H3;6-11,14-15,31H,12-13,16H2,1-5H3;3-8,11-12,36H,9-10,13H2,1-2H3,(H,34,35);3-8,11-12,36H,9-10,13H2,1-2H3,(H2,32,35)
InChIKeyJUFSZXWDIZPEIQ-UHFFFAOYSA-N
MW3640.63 g/mol
LogP34.09
Rot. Bonds75

About 5-amino-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;1-[4-(2-aminoethoxy)-3-methoxyphenyl]-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;2-[2-bromo-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetic acid;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-fluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-5-hydroxypentan-1-one;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4,5-dihydroxypentan-1-one;4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxy-1-[3-methoxy-4-(methylsulfonylmethoxy)phenyl]pentan-1-one;2-[2-fluoro-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide

5-amino-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;1-[4-(2-aminoethoxy)-3-methoxyphenyl]-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;2-[2-bromo-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetic acid;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-fluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-5-hydroxypentan-1-one;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4,5-dihydroxypentan-1-one;4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxy-1-[3-methoxy-4-(methylsulfonylmethoxy)phenyl]pentan-1-one;2-[2-fluoro-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide (PubChem CID 159025533) has the molecular formula C190H196BrF15N10O39S and a molecular weight of 3640.63 g/mol. Its IUPAC name is 5-amino-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;1-[4-(2-aminoethoxy)-3-methoxyphenyl]-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;2-[2-bromo-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetic acid;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-fluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-5-hydroxypentan-1-one;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4,5-dihydroxypentan-1-one;4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxy-1-[3-methoxy-4-(methylsulfonylmethoxy)phenyl]pentan-1-one;2-[2-fluoro-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide.

Molecular Properties

Compound Name5-amino-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;1-[4-(2-aminoethoxy)-3-methoxyphenyl]-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;2-[2-bromo-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetic acid;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-fluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-5-hydroxypentan-1-one;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4,5-dihydroxypentan-1-one;4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxy-1-[3-methoxy-4-(methylsulfonylmethoxy)phenyl]pentan-1-one;2-[2-fluoro-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide
PubChem CID159025533
Molecular FormulaC190H196BrF15N10O39S
Molecular Weight3640.63 g/mol
Exact Mass3637.23
IUPAC Name5-amino-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;1-[4-(2-aminoethoxy)-3-methoxyphenyl]-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;2-[2-bromo-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetic acid;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-fluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-5-hydroxypentan-1-one;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4,5-dihydroxypentan-1-one;4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxy-1-[3-methoxy-4-(methylsulfonylmethoxy)phenyl]pentan-1-one;2-[2-fluoro-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide
SMILESCOc1cc(C(=O)CCC(C)(O)c2ccc(OC)c(-c3ccc(F)c(C)c3)n2)ccc1OCCN.COc1cc(C(=O)CCC(C)(O)c2ccc(OC)c(-c3ccc(F)c(C)c3)n2)ccc1OCS(C)(=O)=O.COc1cc(C(=O)CCC(F)(CO)c2ccc(OC)c(-c3ccc(F)c(C)c3)n2)ccc1OC1CC1.COc1cc(C(=O)CCC(O)(CN)c2ccc(OC)c(-c3ccc(F)c(C)c3)n2)ccc1OC1CC1.COc1cc(C(=O)CCC(O)(CO)c2ccc(OC)c(-c3ccc(F)c(C)c3)n2)ccc1OC1CC1.COc1ccc(C(O)(CCC(=O)c2ccc(OCC(=O)O)c(Br)c2)C(F)(F)F)nc1-c1ccc(F)c(C)c1.COc1ccc(C(O)(CCC(=O)c2ccc(OCC(N)=O)c(F)c2)C(F)(F)F)nc1-c1ccc(F)c(C)c1
InChIInChI=1S/C28H29F2NO5.C28H31FN2O5.C28H30FNO6.C27H31FN2O5.C27H30FNO7S.C26H22BrF4NO6.C26H23F5N2O5/c1-17-14-19(4-8-21(17)29)27-24(34-2)10-11-26(31-27)28(30,16-32)13-12-22(33)18-5-9-23(25(15-18)35-3)36-20-6-7-20;1-17-14-19(4-8-21(17)29)27-24(34-2)10-11-26(31-27)28(33,16-30)13-12-22(32)18-5-9-23(25(15-18)35-3)36-20-6-7-20;1-17-14-19(4-8-21(17)29)27-24(34-2)10-11-26(30-27)28(33,16-31)13-12-22(32)18-5-9-23(25(15-18)35-3)36-20-6-7-20;1-17-15-19(5-7-20(17)28)26-23(33-3)9-10-25(30-26)27(2,32)12-11-21(31)18-6-8-22(35-14-13-29)24(16-18)34-4;1-17-14-19(6-8-20(17)28)26-23(34-3)10-11-25(29-26)27(2,31)13-12-21(30)18-7-9-22(24(15-18)35-4)36-16-37(5,32)33;1-14-11-16(3-5-18(14)28)24-21(37-2)7-8-22(32-24)25(36,26(29,30)31)10-9-19(33)15-4-6-20(17(27)12-15)38-13-23(34)35;1-14-11-16(3-5-17(14)27)24-21(37-2)7-8-22(33-24)25(36,26(29,30)31)10-9-19(34)15-4-6-20(18(28)12-15)38-13-23(32)35/h4-5,8-11,14-15,20,32H,6-7,12-13,16H2,1-3H3;4-5,8-11,14-15,20,33H,6-7,12-13,16,30H2,1-3H3;4-5,8-11,14-15,20,31,33H,6-7,12-13,16H2,1-3H3;5-10,15-16,32H,11-14,29H2,1-4H3;6-11,14-15,31H,12-13,16H2,1-5H3;3-8,11-12,36H,9-10,13H2,1-2H3,(H,34,35);3-8,11-12,36H,9-10,13H2,1-2H3,(H2,32,35)
InChIKeyJUFSZXWDIZPEIQ-UHFFFAOYSA-N
XLogP34.09
TPSA713.50 Ų
H-Bond Donors12
H-Bond Acceptors47
Rotatable Bonds75
Heavy Atoms256
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003640.63
LogP ≤ 534.09
H-Bond Donors ≤ 512
H-Bond Acceptors ≤ 1047

Analyze 5-amino-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;1-[4-(2-aminoethoxy)-3-methoxyphenyl]-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;2-[2-bromo-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetic acid;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-fluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-5-hydroxypentan-1-one;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4,5-dihydroxypentan-1-one;4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxy-1-[3-methoxy-4-(methylsulfonylmethoxy)phenyl]pentan-1-one;2-[2-fluoro-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide with MolForge

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Related Compounds

3-Amino-2-(6-bromo-5-methoxy-2-pyridinyl)-1,1,1-trifluoropropan-2-ol;5-bromo-2-fluorobenzaldehyde;4-bromo-1-fluoro-2-(1-fluoroethyl)benzene;1-(5-bromo-2-fluorophenyl)ethanol;2-bromo-6-iodo-3-methoxypyridine;1-(6-bromo-5-methoxy-2-pyridinyl)ethanone;bis(2-[4-[4-(6-bromo-5-methoxy-2-pyridinyl)-5,5,5-trifluoro-4-hydroxypentanoyl]-2-methoxyphenoxy]acetamide);2-(6-bromo-5-methoxy-2-pyridinyl)-1,1,1-trifluoro-3-nitropropan-2-ol;2-[4-fluoro-3-(1-fluoroethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;methane;bis(2-[2-methoxy-4-[5,5,5-trifluoro-4-[6-[4-fluoro-3-(1-fluoroethyl)phenyl]-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide)
CID 157957545
2-[4-[4-(6-Bromo-5-methoxy-2-pyridinyl)-5,5,5-trifluoro-4-hydroxypentanoyl]-2-methoxyphenoxy]acetamide;tetrakis(2-[2-methoxy-4-[5,5,5-trifluoro-4-[6-[4-fluoro-3-(1-fluoroethyl)phenyl]-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide)
CID 159216773
2-[4-[4-[4-(2-acetamidopropan-2-yl)-6-(4-methylphenyl)-2-pyridinyl]-5,5,5-trifluoro-4-hydroxypentanoyl]-2-methoxyphenoxy]acetamide;2-[4-[4-[4-(2-aminopropan-2-yl)-6-(4-fluoro-3-methylphenyl)-2-pyridinyl]-5,5,5-trifluoro-4-hydroxypentanoyl]-2-methoxyphenoxy]-N-methylsulfonylacetamide;(4R)-4-[4-(2-aminopropan-2-yl)-6-(4-methylphenyl)-2-pyridinyl]-5,5,5-trifluoro-4-hydroxy-1-[4-(2-hydroxyethoxy)-3-methoxyphenyl]pentan-1-one;N-[2-[2-(4-fluoro-3-methylphenyl)-6-[1,1,1-trifluoro-2-hydroxy-5-[4-[(2R)-2-hydroxypropoxy]-3-methoxyphenyl]-5-oxopentan-2-yl]-4-pyridinyl]propan-2-yl]acetamide;methyl 2-amino-2-[2-[5-(4-cyclopropyloxy-3-methoxyphenyl)-1,1,1-trifluoro-2-hydroxy-5-oxopentan-2-yl]-6-(4-methylphenyl)-4-pyridinyl]propanoate;5,5,5-trifluoro-4-hydroxy-1-[4-(2-hydroxyethoxy)-3-methoxyphenyl]-4-[5-methoxy-6-(4-methylphenyl)-2-pyridinyl]pentan-1-one
CID 160658315
CID 160929269
CID 160929269
4-[4-(1-aminoethyl)-6-(4-fluoro-3-methylphenyl)-2-pyridinyl]-1-(4-cyclopropyloxy-3-methoxyphenyl)-5,5,5-trifluoro-4-hydroxypentan-1-one;4-[4-(2-aminopropan-2-yl)-6-(4-fluoro-3-methylphenyl)-2-pyridinyl]-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-hydroxypentan-1-one;4-(azetidin-3-yl)-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxybutan-1-one;5-(azetidin-1-yl)-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;5-(azetidin-3-yl)-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;2-[2-methoxy-4-[5,5,5-trifluoro-4-[6-[4-fluoro-3-[(1R)-1-fluoroethyl]phenyl]-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide
CID 161029107
2-[2-Methoxy-4-[5,5,5-trifluoro-4-[6-[4-fluoro-3-(1-fluoroethyl)phenyl]-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide
CID 161416029
1-[4-(2-Aminoethoxy)-3-methoxyphenyl]-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;2-[2-bromo-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetic acid;2-[4-[4-[3-fluoro-6-(4-fluoro-3-methylphenyl)-2-pyridinyl]-4-hydroxypentanoyl]-2-methoxyphenoxy]acetamide;4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxy-1-(3-methoxy-4-propan-2-yloxyphenyl)pentan-1-one;[4-[4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]-2-methoxyphenoxy]methanesulfonyl fluoride;2-[2-fluoro-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide
CID 167568267
4-[4-(1-aminocyclobutyl)-6-(4-fluoro-3-methylphenyl)-2-pyridinyl]-1-(4-cyclopropyloxy-3-methoxyphenyl)-5,5,5-trifluoro-4-hydroxypentan-1-one;1-[4-(2-aminoethoxy)-3-methoxyphenyl]-4-[4-ethyl-6-(4-fluoro-3-methylphenyl)-2-pyridinyl]-4-hydroxypentan-1-one;4-[4-(aminomethyl)-6-(4-fluoro-3-methylphenyl)-2-pyridinyl]-5,5,5-trifluoro-4-hydroxy-1-[4-(2-hydroxypropoxy)-3-methoxyphenyl]pentan-1-one;1-(4-cyclopropyloxy-3-methoxyphenyl)-5,5,5-trifluoro-4-[4-[2-(2-fluoroethylamino)propan-2-yl]-6-(4-fluoro-3-methylphenyl)-2-pyridinyl]-4-hydroxypentan-1-one;N-[1-[2-[5-(4-cyclopropyloxy-3-methoxyphenyl)-1,1,1-trifluoro-2-hydroxy-5-oxopentan-2-yl]-6-(4-fluoro-3-methylphenyl)-4-pyridinyl]cyclobutyl]acetamide;1-[4-(2,2-difluorocyclopropyl)oxy-3-methoxyphenyl]-5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one
CID 167611367
(4R)-4-cyclopropyl-1-[4-(2-fluoroethoxy)-3-methoxyphenyl]-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxybutan-1-one;(4S)-4-cyclopropyl-1-[4-(2-fluoroethoxy)-3-methoxyphenyl]-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxybutan-1-one;2-[4-[(4R)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]-2-methoxyphenoxy]acetamide;2-[4-[(4S)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]-2-methoxyphenoxy]acetamide;2-[4-[4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]-2-methoxyphenoxy]acetamide;2-[2-methoxy-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]-N-methylacetamide
CID 167614004
2-[4-[4-[4-(2-acetamidopropan-2-yl)-6-(4-methylphenyl)-2-pyridinyl]-5,5,5-trifluoro-4-hydroxypentanoyl]-2-methoxyphenoxy]acetamide;(4S)-4-[4-(2-aminopropan-2-yl)-6-(4-methylphenyl)-2-pyridinyl]-5,5,5-trifluoro-4-hydroxy-1-[4-(2-hydroxyethoxy)-3-methoxyphenyl]pentan-1-one;(4R)-4-[4-(2-aminopropan-2-yl)-6-(4-methylphenyl)-2-pyridinyl]-5,5,5-trifluoro-4-hydroxy-1-[4-(2-hydroxyethoxy)-3-methoxyphenyl]pentan-1-one;N-[2-[2-(4-fluoro-3-methylphenyl)-6-[1,1,1-trifluoro-2-hydroxy-5-[4-[(2R)-2-hydroxypropoxy]-3-methoxyphenyl]-5-oxopentan-2-yl]-4-pyridinyl]propan-2-yl]acetamide;methyl 2-amino-2-[2-[5-(4-cyclopropyloxy-3-methoxyphenyl)-1,1,1-trifluoro-2-hydroxy-5-oxopentan-2-yl]-6-(4-methylphenyl)-4-pyridinyl]propanoate;5,5,5-trifluoro-4-hydroxy-1-[4-(2-hydroxyethoxy)-3-methoxyphenyl]-4-[5-methoxy-6-(4-methylphenyl)-2-pyridinyl]pentan-1-one
CID 167662812
(4R)-4-cyclopropyl-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxy-1-[4-(2-hydroxyethoxy)-3-methoxyphenyl]butan-1-one;(4S)-4-cyclopropyl-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxy-1-[4-(2-hydroxyethoxy)-3-methoxyphenyl]butan-1-one;4-cyclopropyl-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxy-1-[4-(2-hydroxyethoxy)-3-methoxyphenyl]butan-1-one;1-[4-(3,3-difluorocyclobutyl)oxy-3-methoxyphenyl]-5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;2-[4-[4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]-2-methoxyphenoxy]acetamide;2-[2-methoxy-4-[(4S)-5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide
CID 167684378
4-[5-(2-aminoethoxy)-6-(4-fluorophenyl)-2-pyridinyl]-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-hydroxypentan-1-one;tert-butyl N-[2-[[6-(1-amino-2-hydroxypropan-2-yl)-2-(4-fluorophenyl)-3-pyridinyl]oxy]ethyl]carbamate;tert-butyl N-[2-[[6-[5-(4-cyclopropyloxy-3-methoxyphenyl)-2-hydroxy-5-oxopentan-2-yl]-2-(4-fluorophenyl)-3-pyridinyl]oxy]ethyl]carbamate;tert-butyl N-[2-[[2-(4-fluorophenyl)-6-(2-methyloxiran-2-yl)-3-pyridinyl]oxy]ethyl]carbamate;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[5-[2-(dimethylamino)ethoxy]-6-(4-fluorophenyl)-2-pyridinyl]-4-hydroxypentan-1-one
CID 158595499

Frequently Asked Questions

What is the IUPAC name of 5-amino-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;1-[4-(2-aminoethoxy)-3-methoxyphenyl]-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;2-[2-bromo-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetic acid;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-fluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-5-hydroxypentan-1-one;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4,5-dihydroxypentan-1-one;4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxy-1-[3-methoxy-4-(methylsulfonylmethoxy)phenyl]pentan-1-one;2-[2-fluoro-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide?
The IUPAC name of 5-amino-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;1-[4-(2-aminoethoxy)-3-methoxyphenyl]-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;2-[2-bromo-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetic acid;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-fluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-5-hydroxypentan-1-one;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4,5-dihydroxypentan-1-one;4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxy-1-[3-methoxy-4-(methylsulfonylmethoxy)phenyl]pentan-1-one;2-[2-fluoro-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide (CID 159025533) is 5-amino-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;1-[4-(2-aminoethoxy)-3-methoxyphenyl]-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;2-[2-bromo-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetic acid;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-fluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-5-hydroxypentan-1-one;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4,5-dihydroxypentan-1-one;4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxy-1-[3-methoxy-4-(methylsulfonylmethoxy)phenyl]pentan-1-one;2-[2-fluoro-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide.
What is the SMILES notation for 5-amino-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;1-[4-(2-aminoethoxy)-3-methoxyphenyl]-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;2-[2-bromo-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetic acid;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-fluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-5-hydroxypentan-1-one;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4,5-dihydroxypentan-1-one;4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxy-1-[3-methoxy-4-(methylsulfonylmethoxy)phenyl]pentan-1-one;2-[2-fluoro-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide?
The canonical SMILES for 5-amino-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;1-[4-(2-aminoethoxy)-3-methoxyphenyl]-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;2-[2-bromo-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetic acid;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-fluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-5-hydroxypentan-1-one;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4,5-dihydroxypentan-1-one;4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxy-1-[3-methoxy-4-(methylsulfonylmethoxy)phenyl]pentan-1-one;2-[2-fluoro-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide is COc1cc(C(=O)CCC(C)(O)c2ccc(OC)c(-c3ccc(F)c(C)c3)n2)ccc1OCCN.COc1cc(C(=O)CCC(C)(O)c2ccc(OC)c(-c3ccc(F)c(C)c3)n2)ccc1OCS(C)(=O)=O.COc1cc(C(=O)CCC(F)(CO)c2ccc(OC)c(-c3ccc(F)c(C)c3)n2)ccc1OC1CC1.COc1cc(C(=O)CCC(O)(CN)c2ccc(OC)c(-c3ccc(F)c(C)c3)n2)ccc1OC1CC1.COc1cc(C(=O)CCC(O)(CO)c2ccc(OC)c(-c3ccc(F)c(C)c3)n2)ccc1OC1CC1.COc1ccc(C(O)(CCC(=O)c2ccc(OCC(=O)O)c(Br)c2)C(F)(F)F)nc1-c1ccc(F)c(C)c1.COc1ccc(C(O)(CCC(=O)c2ccc(OCC(N)=O)c(F)c2)C(F)(F)F)nc1-c1ccc(F)c(C)c1.
What is the InChIKey of 5-amino-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;1-[4-(2-aminoethoxy)-3-methoxyphenyl]-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;2-[2-bromo-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetic acid;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-fluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-5-hydroxypentan-1-one;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4,5-dihydroxypentan-1-one;4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxy-1-[3-methoxy-4-(methylsulfonylmethoxy)phenyl]pentan-1-one;2-[2-fluoro-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide?
The InChIKey is JUFSZXWDIZPEIQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H29F2NO5.C28H31FN2O5.C28H30FNO6.C27H31FN2O5.C27H30FNO7S.C26H22BrF4NO6.C26H23F5N2O5/c1-17-14-19(4-8-21(17)29)27-24(34-2)10-11-26(31-27)28(30,16-32)13-12-22(33)18-5-9-23(25(15-18)35-3)36-20-6-7-20;1-17-14-19(4-8-21(17)29)27-24(34-2)10-11-26(31-27)28(33,16-30)13-12-22(32)18-5-9-23(25(15-18)35-3)36-20-6-7-20;1-17-14-19(4-8-21(17)29)27-24(34-2)10-11-26(30-27)28(33,16-31)13-12-22(32)18-5-9-23(25(15-18)35-3)36-20-6-7-20;1-17-15-19(5-7-20(17)28)26-23(33-3)9-10-25(30-26)27(2,32)12-11-21(31)18-6-8-22(35-14-13-29)24(16-18)34-4;1-17-14-19(6-8-20(17)28)26-23(34-3)10-11-25(29-26)27(2,31)13-12-21(30)18-7-9-22(24(15-18)35-4)36-16-37(5,32)33;1-14-11-16(3-5-18(14)28)24-21(37-2)7-8-22(32-24)25(36,26(29,30)31)10-9-19(33)15-4-6-20(17(27)12-15)38-13-23(34)35;1-14-11-16(3-5-17(14)27)24-21(37-2)7-8-22(33-24)25(36,26(29,30)31)10-9-19(34)15-4-6-20(18(28)12-15)38-13-23(32)35/h4-5,8-11,14-15,20,32H,6-7,12-13,16H2,1-3H3;4-5,8-11,14-15,20,33H,6-7,12-13,16,30H2,1-3H3;4-5,8-11,14-15,20,31,33H,6-7,12-13,16H2,1-3H3;5-10,15-16,32H,11-14,29H2,1-4H3;6-11,14-15,31H,12-13,16H2,1-5H3;3-8,11-12,36H,9-10,13H2,1-2H3,(H,34,35);3-8,11-12,36H,9-10,13H2,1-2H3,(H2,32,35).
What are the key properties of 5-amino-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;1-[4-(2-aminoethoxy)-3-methoxyphenyl]-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;2-[2-bromo-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetic acid;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-fluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-5-hydroxypentan-1-one;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4,5-dihydroxypentan-1-one;4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxy-1-[3-methoxy-4-(methylsulfonylmethoxy)phenyl]pentan-1-one;2-[2-fluoro-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide?
5-amino-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;1-[4-(2-aminoethoxy)-3-methoxyphenyl]-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;2-[2-bromo-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetic acid;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-fluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-5-hydroxypentan-1-one;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4,5-dihydroxypentan-1-one;4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxy-1-[3-methoxy-4-(methylsulfonylmethoxy)phenyl]pentan-1-one;2-[2-fluoro-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide has a molecular weight of 3640.63 g/mol, XLogP of 34.09, 75 rotatable bonds, 12 hydrogen bond donors, and 47 hydrogen bond acceptors.
Where does this data come from?
All data for 5-amino-1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;1-[4-(2-aminoethoxy)-3-methoxyphenyl]-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentan-1-one;2-[2-bromo-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetic acid;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-fluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-5-hydroxypentan-1-one;1-(4-cyclopropyloxy-3-methoxyphenyl)-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4,5-dihydroxypentan-1-one;4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxy-1-[3-methoxy-4-(methylsulfonylmethoxy)phenyl]pentan-1-one;2-[2-fluoro-4-[5,5,5-trifluoro-4-[6-(4-fluoro-3-methylphenyl)-5-methoxy-2-pyridinyl]-4-hydroxypentanoyl]phenoxy]acetamide is sourced from PubChem (CID 159025533), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).