(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(1,3-dimethylpyrazol-4-yl)isoquinolin-8-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one

C125H126F4N30O5 — CID 159034977

About (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(1,3-dimethylpyrazol-4-yl)isoquinolin-8-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one

(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(1,3-dimethylpyrazol-4-yl)isoquinolin-8-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one (PubChem CID 159034977) has the molecular formula C125H126F4N30O5 and a molecular weight of 2204.58 g/mol. Its IUPAC name is (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(1,3-dimethylpyrazol-4-yl)isoquinolin-8-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one.

Molecular Properties

• Compound Name: (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(1,3-dimethylpyrazol-4-yl)isoquinolin-8-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one
• PubChem CID: 159034977
• Molecular Formula: C125H126F4N30O5
• Molecular Weight: 2204.58 g/mol
• Exact Mass: 2203.05
• IUPAC Name: (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(1,3-dimethylpyrazol-4-yl)isoquinolin-8-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one
• SMILES: C[C@@H]1C(=O)N(C)Cc2c(-c3cccc4cc(-c5ccn(C)n5)ncc34)nc(C3CC3)n21.C[C@H]1C(=O)N(C)Cc2c(-c3cccc4cc(-c5ccn(C)n5)ncc34)nc(C3CC3)n21.Cc1c(-c2nc3cccc(-c4nc(C5CC5)n5c4CN(C)C(=O)[C@@H]5C)c3cc2C(F)F)cnn1C.Cc1c(-c2nc3cccc(-c4nc(C5CC5)n5c4CN(C)C(=O)[C@H]5C)c3cc2C(F)F)cnn1C.Cc1nn(C)cc1-c1cc2cccc(-c3nc(C4CC4)n4c3CN(C)C(=O)[C@H]4C)c2cn1
• InChI: InChI=1S/2C26H26F2N6O.C25H26N6O.2C24H24N6O/c2*1-13-19(11-29-33(13)4)22-18(24(27)28)10-17-16(6-5-7-20(17)30-22)23-21-12-32(3)26(35)14(2)34(21)25(31-23)15-8-9-15;1-14-20(12-30(4)28-14)21-10-17-6-5-7-18(19(17)11-26-21)23-22-13-29(3)25(32)15(2)31(22)24(27-23)16-8-9-16;2*1-14-24(31)28(2)13-21-22(26-23(30(14)21)15-7-8-15)17-6-4-5-16-11-20(25-12-18(16)17)19-9-10-29(3)27-19/h2*5-7,10-11,14-15,24H,8-9,12H2,1-4H3;5-7,10-12,15-16H,8-9,13H2,1-4H3;2*4-6,9-12,14-15H,7-8,13H2,1-3H3/t2*14-;15-;2*14-/m10110/s1
• InChIKey: JVIRYCFZYWKJJE-HZANLVSLSA-N
• XLogP: 22.35
• TPSA: 344.20 Ų
• H-Bond Acceptors: 30
• Rotatable Bonds: 17
• Heavy Atoms: 164
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2204.58
LogP ≤ 5	22.35
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	30

Frequently Asked Questions

What is the IUPAC name of (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(1,3-dimethylpyrazol-4-yl)isoquinolin-8-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one?

The IUPAC name of (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(1,3-dimethylpyrazol-4-yl)isoquinolin-8-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one (CID 159034977) is (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(1,3-dimethylpyrazol-4-yl)isoquinolin-8-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one.

What is the SMILES notation for (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(1,3-dimethylpyrazol-4-yl)isoquinolin-8-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one?

The canonical SMILES for (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(1,3-dimethylpyrazol-4-yl)isoquinolin-8-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one is C[C@@H]1C(=O)N(C)Cc2c(-c3cccc4cc(-c5ccn(C)n5)ncc34)nc(C3CC3)n21.C[C@H]1C(=O)N(C)Cc2c(-c3cccc4cc(-c5ccn(C)n5)ncc34)nc(C3CC3)n21.Cc1c(-c2nc3cccc(-c4nc(C5CC5)n5c4CN(C)C(=O)[C@@H]5C)c3cc2C(F)F)cnn1C.Cc1c(-c2nc3cccc(-c4nc(C5CC5)n5c4CN(C)C(=O)[C@H]5C)c3cc2C(F)F)cnn1C.Cc1nn(C)cc1-c1cc2cccc(-c3nc(C4CC4)n4c3CN(C)C(=O)[C@H]4C)c2cn1.

What is the InChIKey of (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(1,3-dimethylpyrazol-4-yl)isoquinolin-8-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one?

The InChIKey is JVIRYCFZYWKJJE-HZANLVSLSA-N. The full InChI is InChI=1S/2C26H26F2N6O.C25H26N6O.2C24H24N6O/c2*1-13-19(11-29-33(13)4)22-18(24(27)28)10-17-16(6-5-7-20(17)30-22)23-21-12-32(3)26(35)14(2)34(21)25(31-23)15-8-9-15;1-14-20(12-30(4)28-14)21-10-17-6-5-7-18(19(17)11-26-21)23-22-13-29(3)25(32)15(2)31(22)24(27-23)16-8-9-16;2*1-14-24(31)28(2)13-21-22(26-23(30(14)21)15-7-8-15)17-6-4-5-16-11-20(25-12-18(16)17)19-9-10-29(3)27-19/h2*5-7,10-11,14-15,24H,8-9,12H2,1-4H3;5-7,10-12,15-16H,8-9,13H2,1-4H3;2*4-6,9-12,14-15H,7-8,13H2,1-3H3/t2*14-;15-;2*14-/m10110/s1.

What are the key properties of (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(1,3-dimethylpyrazol-4-yl)isoquinolin-8-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one?

(5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(1,3-dimethylpyrazol-4-yl)isoquinolin-8-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one has a molecular weight of 2204.58 g/mol, XLogP of 22.35, 17 rotatable bonds, 0 hydrogen bond donors, and 30 hydrogen bond acceptors.

Where does this data come from?

All data for (5R)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-1-[3-(difluoromethyl)-2-(1,5-dimethylpyrazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5S)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-5,7-dimethyl-1-[3-(1-methylpyrazol-3-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;(5R)-3-cyclopropyl-1-[3-(1,3-dimethylpyrazol-4-yl)isoquinolin-8-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one is sourced from PubChem (CID 159034977), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).