2-(4-hydroxy-3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;2-(3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(1-methyl-2-oxoimidazo[4,5-c]pyridin-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(3-methyl-2-oxoimidazo[4,5-c]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2R)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2S)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide

C139H163N45O17S6 — CID 159038284

About 2-(4-hydroxy-3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;2-(3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(1-methyl-2-oxoimidazo[4,5-c]pyridin-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(3-methyl-2-oxoimidazo[4,5-c]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2R)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2S)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide

2-(4-hydroxy-3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;2-(3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(1-methyl-2-oxoimidazo[4,5-c]pyridin-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(3-methyl-2-oxoimidazo[4,5-c]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2R)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2S)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide (PubChem CID 159038284) has the molecular formula C139H163N45O17S6 and a molecular weight of 2928.53 g/mol. Its IUPAC name is 2-(4-hydroxy-3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;2-(3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(1-methyl-2-oxoimidazo[4,5-c]pyridin-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(3-methyl-2-oxoimidazo[4,5-c]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2R)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2S)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide.

Molecular Properties

• Compound Name: 2-(4-hydroxy-3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;2-(3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(1-methyl-2-oxoimidazo[4,5-c]pyridin-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(3-methyl-2-oxoimidazo[4,5-c]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2R)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2S)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide
• PubChem CID: 159038284
• Molecular Formula: C139H163N45O17S6
• Molecular Weight: 2928.53 g/mol
• Exact Mass: 2926.16
• IUPAC Name: 2-(4-hydroxy-3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;2-(3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(1-methyl-2-oxoimidazo[4,5-c]pyridin-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(3-methyl-2-oxoimidazo[4,5-c]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2R)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2S)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide
• SMILES: C.C.C.C.C.C.Cn1c(=O)n(-c2nc(C(=O)Nc3cnccc3N3CCNCC3)cs2)c2cccc(O)c21.Cn1c(=O)n(-c2nc(C(=O)Nc3cnccc3N3CCNCC3)cs2)c2cccc(OC[C@@H]3CCCO3)c21.Cn1c(=O)n(-c2nc(C(=O)Nc3cnccc3N3CCNCC3)cs2)c2cccc(OC[C@H]3CCCO3)c21.Cn1c(=O)n(-c2nc(C(=O)Nc3cnccc3N3CCNCC3)cs2)c2cccnc21.Cn1c(=O)n(-c2nc(C(=O)Nc3cnccc3N3CCNCC3)cs2)c2ccncc21.Cn1c(=O)n(-c2nc(C(=O)Nc3cnccc3N3CCNCC3)cs2)c2cnccc21
• InChI: InChI=1S/2C26H29N7O4S.C21H21N7O3S.3C20H20N8O2S.6CH4/c2*1-31-23-21(5-2-6-22(23)37-15-17-4-3-13-36-17)33(26(31)35)25-30-19(16-38-25)24(34)29-18-14-28-8-7-20(18)32-11-9-27-10-12-32;1-26-18-16(3-2-4-17(18)29)28(21(26)31)20-25-14(12-32-20)19(30)24-13-11-23-6-5-15(13)27-9-7-22-8-10-27;1-26-17-11-23-5-3-16(17)28(20(26)30)19-25-14(12-31-19)18(29)24-13-10-22-4-2-15(13)27-8-6-21-7-9-27;1-26-16-3-5-23-11-17(16)28(20(26)30)19-25-14(12-31-19)18(29)24-13-10-22-4-2-15(13)27-8-6-21-7-9-27;1-26-17-16(3-2-5-23-17)28(20(26)30)19-25-14(12-31-19)18(29)24-13-11-22-6-4-15(13)27-9-7-21-8-10-27;;;;;;/h2*2,5-8,14,16-17,27H,3-4,9-13,15H2,1H3,(H,29,34);2-6,11-12,22,29H,7-10H2,1H3,(H,24,30);2*2-5,10-12,21H,6-9H2,1H3,(H,24,29);2-6,11-12,21H,7-10H2,1H3,(H,24,29);6*1H4/t2*17-;;;;;;;;;;/m10........../s1
• InChIKey: JVSNNWQMAYUHLG-GBWXJMATSA-N
• XLogP: 13.88
• TPSA: 678.30 Ų
• H-Bond Donors: 13
• H-Bond Acceptors: 62
• Rotatable Bonds: 30
• Heavy Atoms: 207
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2928.53
LogP ≤ 5	13.88
H-Bond Donors ≤ 5	13
H-Bond Acceptors ≤ 10	62

Frequently Asked Questions

What is the IUPAC name of 2-(4-hydroxy-3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;2-(3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(1-methyl-2-oxoimidazo[4,5-c]pyridin-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(3-methyl-2-oxoimidazo[4,5-c]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2R)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2S)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide?

The IUPAC name of 2-(4-hydroxy-3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;2-(3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(1-methyl-2-oxoimidazo[4,5-c]pyridin-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(3-methyl-2-oxoimidazo[4,5-c]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2R)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2S)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide (CID 159038284) is 2-(4-hydroxy-3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;2-(3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(1-methyl-2-oxoimidazo[4,5-c]pyridin-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(3-methyl-2-oxoimidazo[4,5-c]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2R)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2S)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide.

What is the SMILES notation for 2-(4-hydroxy-3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;2-(3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(1-methyl-2-oxoimidazo[4,5-c]pyridin-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(3-methyl-2-oxoimidazo[4,5-c]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2R)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2S)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide?

The canonical SMILES for 2-(4-hydroxy-3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;2-(3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(1-methyl-2-oxoimidazo[4,5-c]pyridin-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(3-methyl-2-oxoimidazo[4,5-c]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2R)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2S)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide is C.C.C.C.C.C.Cn1c(=O)n(-c2nc(C(=O)Nc3cnccc3N3CCNCC3)cs2)c2cccc(O)c21.Cn1c(=O)n(-c2nc(C(=O)Nc3cnccc3N3CCNCC3)cs2)c2cccc(OC[C@@H]3CCCO3)c21.Cn1c(=O)n(-c2nc(C(=O)Nc3cnccc3N3CCNCC3)cs2)c2cccc(OC[C@H]3CCCO3)c21.Cn1c(=O)n(-c2nc(C(=O)Nc3cnccc3N3CCNCC3)cs2)c2cccnc21.Cn1c(=O)n(-c2nc(C(=O)Nc3cnccc3N3CCNCC3)cs2)c2ccncc21.Cn1c(=O)n(-c2nc(C(=O)Nc3cnccc3N3CCNCC3)cs2)c2cnccc21.

What is the InChIKey of 2-(4-hydroxy-3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;2-(3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(1-methyl-2-oxoimidazo[4,5-c]pyridin-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(3-methyl-2-oxoimidazo[4,5-c]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2R)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2S)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide?

The InChIKey is JVSNNWQMAYUHLG-GBWXJMATSA-N. The full InChI is InChI=1S/2C26H29N7O4S.C21H21N7O3S.3C20H20N8O2S.6CH4/c2*1-31-23-21(5-2-6-22(23)37-15-17-4-3-13-36-17)33(26(31)35)25-30-19(16-38-25)24(34)29-18-14-28-8-7-20(18)32-11-9-27-10-12-32;1-26-18-16(3-2-4-17(18)29)28(21(26)31)20-25-14(12-32-20)19(30)24-13-11-23-6-5-15(13)27-9-7-22-8-10-27;1-26-17-11-23-5-3-16(17)28(20(26)30)19-25-14(12-31-19)18(29)24-13-10-22-4-2-15(13)27-8-6-21-7-9-27;1-26-16-3-5-23-11-17(16)28(20(26)30)19-25-14(12-31-19)18(29)24-13-10-22-4-2-15(13)27-8-6-21-7-9-27;1-26-17-16(3-2-5-23-17)28(20(26)30)19-25-14(12-31-19)18(29)24-13-11-22-6-4-15(13)27-9-7-21-8-10-27;;;;;;/h2*2,5-8,14,16-17,27H,3-4,9-13,15H2,1H3,(H,29,34);2-6,11-12,22,29H,7-10H2,1H3,(H,24,30);2*2-5,10-12,21H,6-9H2,1H3,(H,24,29);2-6,11-12,21H,7-10H2,1H3,(H,24,29);6*1H4/t2*17-;;;;;;;;;;/m10........../s1.

What are the key properties of 2-(4-hydroxy-3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;2-(3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(1-methyl-2-oxoimidazo[4,5-c]pyridin-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(3-methyl-2-oxoimidazo[4,5-c]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2R)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2S)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide?

2-(4-hydroxy-3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;2-(3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(1-methyl-2-oxoimidazo[4,5-c]pyridin-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(3-methyl-2-oxoimidazo[4,5-c]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2R)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2S)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide has a molecular weight of 2928.53 g/mol, XLogP of 13.88, 30 rotatable bonds, 13 hydrogen bond donors, and 62 hydrogen bond acceptors.

Where does this data come from?

All data for 2-(4-hydroxy-3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;methane;2-(3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(1-methyl-2-oxoimidazo[4,5-c]pyridin-3-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-(3-methyl-2-oxoimidazo[4,5-c]pyridin-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2R)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;2-[3-methyl-2-oxo-4-[[(2S)-oxolan-2-yl]methoxy]benzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide is sourced from PubChem (CID 159038284), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).