4-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile;5-(3-methoxyphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N,N-dimethylbenzamide;N-(2-methyl-4-pyridinyl)-5-(3-propan-2-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[2-(4-morpholin-4-ylanilino)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]benzonitrile;N-(4-morpholin-4-ylphenyl)-5-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine

C125H114F3N31O6 — CID 159042929

About 4-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile;5-(3-methoxyphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N,N-dimethylbenzamide;N-(2-methyl-4-pyridinyl)-5-(3-propan-2-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[2-(4-morpholin-4-ylanilino)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]benzonitrile;N-(4-morpholin-4-ylphenyl)-5-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine

4-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile;5-(3-methoxyphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N,N-dimethylbenzamide;N-(2-methyl-4-pyridinyl)-5-(3-propan-2-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[2-(4-morpholin-4-ylanilino)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]benzonitrile;N-(4-morpholin-4-ylphenyl)-5-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine (PubChem CID 159042929) has the molecular formula C125H114F3N31O6 and a molecular weight of 2203.49 g/mol. Its IUPAC name is 4-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile;5-(3-methoxyphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N,N-dimethylbenzamide;N-(2-methyl-4-pyridinyl)-5-(3-propan-2-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[2-(4-morpholin-4-ylanilino)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]benzonitrile;N-(4-morpholin-4-ylphenyl)-5-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine.

Molecular Properties

• Compound Name: 4-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile;5-(3-methoxyphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N,N-dimethylbenzamide;N-(2-methyl-4-pyridinyl)-5-(3-propan-2-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[2-(4-morpholin-4-ylanilino)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]benzonitrile;N-(4-morpholin-4-ylphenyl)-5-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine
• PubChem CID: 159042929
• Molecular Formula: C125H114F3N31O6
• Molecular Weight: 2203.49 g/mol
• Exact Mass: 2201.95
• IUPAC Name: 4-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile;5-(3-methoxyphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N,N-dimethylbenzamide;N-(2-methyl-4-pyridinyl)-5-(3-propan-2-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[2-(4-morpholin-4-ylanilino)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]benzonitrile;N-(4-morpholin-4-ylphenyl)-5-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine
• SMILES: COc1cccc(-c2cccc3nc(Nc4ccc(C(=O)N(C)C)cc4)nn23)c1.COc1cccc(-c2cccc3nc(Nc4ccc(N5CCOCC5)cc4)nn23)c1.Cc1cc(Nc2nc3cccc(-c4cccc(C(C)C)c4)n3n2)ccn1.FC(F)(F)c1cccc(-c2cccc3nc(Nc4ccc(N5CCOCC5)cc4)nn23)c1.N#Cc1ccc(-c2cccc3nc(N)nn23)cc1.N#Cc1ccc(-c2cccc3nc(Nc4ccc(N5CCOCC5)cc4)nn23)cc1
• InChI: InChI=1S/C23H20F3N5O.C23H20N6O.C23H23N5O2.C22H21N5O2.C21H21N5.C13H9N5/c24-23(25,26)17-4-1-3-16(15-17)20-5-2-6-21-28-22(29-31(20)21)27-18-7-9-19(10-8-18)30-11-13-32-14-12-30;24-16-17-4-6-18(7-5-17)21-2-1-3-22-26-23(27-29(21)22)25-19-8-10-20(11-9-19)28-12-14-30-15-13-28;1-29-20-5-2-4-17(16-20)21-6-3-7-22-25-23(26-28(21)22)24-18-8-10-19(11-9-18)27-12-14-30-15-13-27;1-26(2)21(28)15-10-12-17(13-11-15)23-22-24-20-9-5-8-19(27(20)25-22)16-6-4-7-18(14-16)29-3;1-14(2)16-6-4-7-17(13-16)19-8-5-9-20-24-21(25-26(19)20)23-18-10-11-22-15(3)12-18;14-8-9-4-6-10(7-5-9)11-2-1-3-12-16-13(15)17-18(11)12/h1-10,15H,11-14H2,(H,27,29);1-11H,12-15H2,(H,25,27);2-11,16H,12-15H2,1H3,(H,24,26);4-14H,1-3H3,(H,23,25);4-14H,1-3H3,(H,22,23,25);1-7H,(H2,15,17)
• InChIKey: JWHIDZFLMVLQFK-UHFFFAOYSA-N
• XLogP: 23.50
• TPSA: 403.96 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 36
• Rotatable Bonds: 23
• Heavy Atoms: 165
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2203.49
LogP ≤ 5	23.50
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	36

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'anil_di_alk_A(478)', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 4-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile;5-(3-methoxyphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N,N-dimethylbenzamide;N-(2-methyl-4-pyridinyl)-5-(3-propan-2-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[2-(4-morpholin-4-ylanilino)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]benzonitrile;N-(4-morpholin-4-ylphenyl)-5-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine?

The IUPAC name of 4-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile;5-(3-methoxyphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N,N-dimethylbenzamide;N-(2-methyl-4-pyridinyl)-5-(3-propan-2-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[2-(4-morpholin-4-ylanilino)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]benzonitrile;N-(4-morpholin-4-ylphenyl)-5-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine (CID 159042929) is 4-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile;5-(3-methoxyphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N,N-dimethylbenzamide;N-(2-methyl-4-pyridinyl)-5-(3-propan-2-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[2-(4-morpholin-4-ylanilino)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]benzonitrile;N-(4-morpholin-4-ylphenyl)-5-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine.

What is the SMILES notation for 4-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile;5-(3-methoxyphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N,N-dimethylbenzamide;N-(2-methyl-4-pyridinyl)-5-(3-propan-2-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[2-(4-morpholin-4-ylanilino)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]benzonitrile;N-(4-morpholin-4-ylphenyl)-5-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine?

The canonical SMILES for 4-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile;5-(3-methoxyphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N,N-dimethylbenzamide;N-(2-methyl-4-pyridinyl)-5-(3-propan-2-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[2-(4-morpholin-4-ylanilino)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]benzonitrile;N-(4-morpholin-4-ylphenyl)-5-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine is COc1cccc(-c2cccc3nc(Nc4ccc(C(=O)N(C)C)cc4)nn23)c1.COc1cccc(-c2cccc3nc(Nc4ccc(N5CCOCC5)cc4)nn23)c1.Cc1cc(Nc2nc3cccc(-c4cccc(C(C)C)c4)n3n2)ccn1.FC(F)(F)c1cccc(-c2cccc3nc(Nc4ccc(N5CCOCC5)cc4)nn23)c1.N#Cc1ccc(-c2cccc3nc(N)nn23)cc1.N#Cc1ccc(-c2cccc3nc(Nc4ccc(N5CCOCC5)cc4)nn23)cc1.

What is the InChIKey of 4-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile;5-(3-methoxyphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N,N-dimethylbenzamide;N-(2-methyl-4-pyridinyl)-5-(3-propan-2-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[2-(4-morpholin-4-ylanilino)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]benzonitrile;N-(4-morpholin-4-ylphenyl)-5-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine?

The InChIKey is JWHIDZFLMVLQFK-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H20F3N5O.C23H20N6O.C23H23N5O2.C22H21N5O2.C21H21N5.C13H9N5/c24-23(25,26)17-4-1-3-16(15-17)20-5-2-6-21-28-22(29-31(20)21)27-18-7-9-19(10-8-18)30-11-13-32-14-12-30;24-16-17-4-6-18(7-5-17)21-2-1-3-22-26-23(27-29(21)22)25-19-8-10-20(11-9-19)28-12-14-30-15-13-28;1-29-20-5-2-4-17(16-20)21-6-3-7-22-25-23(26-28(21)22)24-18-8-10-19(11-9-18)27-12-14-30-15-13-27;1-26(2)21(28)15-10-12-17(13-11-15)23-22-24-20-9-5-8-19(27(20)25-22)16-6-4-7-18(14-16)29-3;1-14(2)16-6-4-7-17(13-16)19-8-5-9-20-24-21(25-26(19)20)23-18-10-11-22-15(3)12-18;14-8-9-4-6-10(7-5-9)11-2-1-3-12-16-13(15)17-18(11)12/h1-10,15H,11-14H2,(H,27,29);1-11H,12-15H2,(H,25,27);2-11,16H,12-15H2,1H3,(H,24,26);4-14H,1-3H3,(H,23,25);4-14H,1-3H3,(H,22,23,25);1-7H,(H2,15,17).

What are the key properties of 4-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile;5-(3-methoxyphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N,N-dimethylbenzamide;N-(2-methyl-4-pyridinyl)-5-(3-propan-2-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[2-(4-morpholin-4-ylanilino)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]benzonitrile;N-(4-morpholin-4-ylphenyl)-5-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine?

4-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile;5-(3-methoxyphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N,N-dimethylbenzamide;N-(2-methyl-4-pyridinyl)-5-(3-propan-2-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[2-(4-morpholin-4-ylanilino)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]benzonitrile;N-(4-morpholin-4-ylphenyl)-5-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine has a molecular weight of 2203.49 g/mol, XLogP of 23.50, 23 rotatable bonds, 6 hydrogen bond donors, and 36 hydrogen bond acceptors.

Where does this data come from?

All data for 4-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile;5-(3-methoxyphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[[5-(3-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]-N,N-dimethylbenzamide;N-(2-methyl-4-pyridinyl)-5-(3-propan-2-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;4-[2-(4-morpholin-4-ylanilino)-[1,2,4]triazolo[1,5-a]pyridin-5-yl]benzonitrile;N-(4-morpholin-4-ylphenyl)-5-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine is sourced from PubChem (CID 159042929), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).