4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N,N-dimethylbenzamide;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-3-(5-methoxypyrazin-2-yl)-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;5-[1-(cyclopropylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-1H-pyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-hydroxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(3-methoxypropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile

C259H329F3N52O17 — CID 159048837

IUPAC4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N,N-dimethylbenzamide;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-3-(5-methoxypyrazin-2-yl)-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;5-[1-(cyclopropylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-1H-pyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-hydroxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(3-methoxypropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile
SMILESCC(C)CN1C(=O)N(c2cnc(C#N)nc2)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C(=O)c1ccc(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)cc1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc(C(N)=O)cc1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(=O)[nH]c1)C(=O)N2CC1(O)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)nc1)C(=O)N2CC1CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)nc1)C(=O)N2CCO.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(C(F)(F)F)nc1)C(=O)N2CC1CCC1.CNC1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)cc1C)C(=O)N2CC1CCC1.CNC1(c2ccccc2)CCC2(CC1)CN(c1cnc(OC)cn1)C(=O)N2CC1CCC1.COCCCN1C(=O)N(c2cnc(C#N)nc2)CC12CCC(c1ccccc1)(N(C)C)CC2
InChIInChI=1S/C30H40N4O2.C28H36N4O2.C27H33N5O.C26H32F3N5O.C25H32N6O2.C25H30N6O.C25H32N6O.C25H33N5O3.C25H33N5O2.C23H28N6O2/c1-31(2)27(35)24-13-15-26(16-14-24)33-22-29(34(28(33)36)21-23-9-8-10-23)17-19-30(20-18-29,32(3)4)25-11-6-5-7-12-25;1-30(2)28(23-9-4-3-5-10-23)17-15-27(16-18-28)20-31(24-13-11-22(12-14-24)25(29)33)26(34)32(27)19-21-7-6-8-21;1-20-15-23(16-28)30-17-24(20)31-19-26(32(25(31)33)18-21-7-6-8-21)11-13-27(29-2,14-12-26)22-9-4-3-5-10-22;1-32(2)25(20-9-4-3-5-10-20)13-11-24(12-14-25)18-33(23(35)34(24)17-19-7-6-8-19)21-15-30-22(31-16-21)26(27,28)29;1-29(2)25(20-8-5-4-6-9-20)12-10-24(11-13-25)19-30(21-17-27-22(16-26)28-18-21)23(32)31(24)14-7-15-33-3;1-29(2)25(20-6-4-3-5-7-20)12-10-24(11-13-25)18-30(21-15-27-22(14-26)28-16-21)23(32)31(24)17-19-8-9-19;1-19(2)17-31-23(32)30(21-15-27-22(14-26)28-16-21)18-24(31)10-12-25(13-11-24,29(3)4)20-8-6-5-7-9-20;1-28(2)25(19-7-4-3-5-8-19)13-11-23(12-14-25)17-29(20-15-26-21(31)27-16-20)22(32)30(23)18-24(33)9-6-10-24;1-26-25(20-9-4-3-5-10-20)13-11-24(12-14-25)18-29(21-15-28-22(32-2)16-27-21)23(31)30(24)17-19-7-6-8-19;1-27(2)23(18-6-4-3-5-7-18)10-8-22(9-11-23)17-28(21(31)29(22)12-13-30)19-15-25-20(14-24)26-16-19/h5-7,11-16,23H,8-10,17-22H2,1-4H3;3-5,9-14,21H,6-8,15-20H2,1-2H3,(H2,29,33);3-5,9-10,15,17,21,29H,6-8,11-14,18-19H2,1-2H3;3-5,9-10,15-16,19H,6-8,11-14,17-18H2,1-2H3;4-6,8-9,17-18H,7,10-15,19H2,1-3H3;3-7,15-16,19H,8-13,17-18H2,1-2H3;5-9,15-16,19H,10-13,17-18H2,1-4H3;3-5,7-8,15-16,33H,6,9-14,17-18H2,1-2H3,(H,26,27,31);3-5,9-10,15-16,19,26H,6-8,11-14,17-18H2,1-2H3;3-7,15-16,30H,8-13,17H2,1-2H3
InChIKeyJWZSKRMFTVPYCU-UHFFFAOYSA-N
MW4499.82 g/mol
LogP40.02
Rot. Bonds55

About 4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N,N-dimethylbenzamide;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-3-(5-methoxypyrazin-2-yl)-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;5-[1-(cyclopropylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-1H-pyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-hydroxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(3-methoxypropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile

4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N,N-dimethylbenzamide;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-3-(5-methoxypyrazin-2-yl)-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;5-[1-(cyclopropylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-1H-pyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-hydroxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(3-methoxypropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile (PubChem CID 159048837) has the molecular formula C259H329F3N52O17 and a molecular weight of 4499.82 g/mol. Its IUPAC name is 4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N,N-dimethylbenzamide;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-3-(5-methoxypyrazin-2-yl)-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;5-[1-(cyclopropylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-1H-pyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-hydroxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(3-methoxypropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile.

Molecular Properties

Compound Name4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N,N-dimethylbenzamide;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-3-(5-methoxypyrazin-2-yl)-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;5-[1-(cyclopropylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-1H-pyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-hydroxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(3-methoxypropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile
PubChem CID159048837
Molecular FormulaC259H329F3N52O17
Molecular Weight4499.82 g/mol
Exact Mass4496.64
IUPAC Name4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N,N-dimethylbenzamide;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-3-(5-methoxypyrazin-2-yl)-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;5-[1-(cyclopropylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-1H-pyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-hydroxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(3-methoxypropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile
SMILESCC(C)CN1C(=O)N(c2cnc(C#N)nc2)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C(=O)c1ccc(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)cc1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc(C(N)=O)cc1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(=O)[nH]c1)C(=O)N2CC1(O)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)nc1)C(=O)N2CC1CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)nc1)C(=O)N2CCO.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(C(F)(F)F)nc1)C(=O)N2CC1CCC1.CNC1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)cc1C)C(=O)N2CC1CCC1.CNC1(c2ccccc2)CCC2(CC1)CN(c1cnc(OC)cn1)C(=O)N2CC1CCC1.COCCCN1C(=O)N(c2cnc(C#N)nc2)CC12CCC(c1ccccc1)(N(C)C)CC2
InChIInChI=1S/C30H40N4O2.C28H36N4O2.C27H33N5O.C26H32F3N5O.C25H32N6O2.C25H30N6O.C25H32N6O.C25H33N5O3.C25H33N5O2.C23H28N6O2/c1-31(2)27(35)24-13-15-26(16-14-24)33-22-29(34(28(33)36)21-23-9-8-10-23)17-19-30(20-18-29,32(3)4)25-11-6-5-7-12-25;1-30(2)28(23-9-4-3-5-10-23)17-15-27(16-18-28)20-31(24-13-11-22(12-14-24)25(29)33)26(34)32(27)19-21-7-6-8-21;1-20-15-23(16-28)30-17-24(20)31-19-26(32(25(31)33)18-21-7-6-8-21)11-13-27(29-2,14-12-26)22-9-4-3-5-10-22;1-32(2)25(20-9-4-3-5-10-20)13-11-24(12-14-25)18-33(23(35)34(24)17-19-7-6-8-19)21-15-30-22(31-16-21)26(27,28)29;1-29(2)25(20-8-5-4-6-9-20)12-10-24(11-13-25)19-30(21-17-27-22(16-26)28-18-21)23(32)31(24)14-7-15-33-3;1-29(2)25(20-6-4-3-5-7-20)12-10-24(11-13-25)18-30(21-15-27-22(14-26)28-16-21)23(32)31(24)17-19-8-9-19;1-19(2)17-31-23(32)30(21-15-27-22(14-26)28-16-21)18-24(31)10-12-25(13-11-24,29(3)4)20-8-6-5-7-9-20;1-28(2)25(19-7-4-3-5-8-19)13-11-23(12-14-25)17-29(20-15-26-21(31)27-16-20)22(32)30(23)18-24(33)9-6-10-24;1-26-25(20-9-4-3-5-10-20)13-11-24(12-14-25)18-29(21-15-28-22(32-2)16-27-21)23(31)30(24)17-19-7-6-8-19;1-27(2)23(18-6-4-3-5-7-18)10-8-22(9-11-23)17-28(21(31)29(22)12-13-30)19-15-25-20(14-24)26-16-19/h5-7,11-16,23H,8-10,17-22H2,1-4H3;3-5,9-14,21H,6-8,15-20H2,1-2H3,(H2,29,33);3-5,9-10,15,17,21,29H,6-8,11-14,18-19H2,1-2H3;3-5,9-10,15-16,19H,6-8,11-14,17-18H2,1-2H3;4-6,8-9,17-18H,7,10-15,19H2,1-3H3;3-7,15-16,19H,8-13,17-18H2,1-2H3;5-9,15-16,19H,10-13,17-18H2,1-4H3;3-5,7-8,15-16,33H,6,9-14,17-18H2,1-2H3,(H,26,27,31);3-5,9-10,15-16,19,26H,6-8,11-14,17-18H2,1-2H3;3-7,15-16,30H,8-13,17H2,1-2H3
InChIKeyJWZSKRMFTVPYCU-UHFFFAOYSA-N
XLogP40.02
TPSA740.07 Ų
H-Bond Donors6
H-Bond Acceptors46
Rotatable Bonds55
Heavy Atoms331
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004499.82
LogP ≤ 540.02
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1046

Analyze 4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N,N-dimethylbenzamide;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-3-(5-methoxypyrazin-2-yl)-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;5-[1-(cyclopropylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-1H-pyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-hydroxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(3-methoxypropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile with MolForge

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What is the IUPAC name of 4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N,N-dimethylbenzamide;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-3-(5-methoxypyrazin-2-yl)-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;5-[1-(cyclopropylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-1H-pyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-hydroxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(3-methoxypropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile?
The IUPAC name of 4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N,N-dimethylbenzamide;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-3-(5-methoxypyrazin-2-yl)-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;5-[1-(cyclopropylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-1H-pyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-hydroxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(3-methoxypropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile (CID 159048837) is 4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N,N-dimethylbenzamide;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-3-(5-methoxypyrazin-2-yl)-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;5-[1-(cyclopropylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-1H-pyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-hydroxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(3-methoxypropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile.
What is the SMILES notation for 4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N,N-dimethylbenzamide;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-3-(5-methoxypyrazin-2-yl)-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;5-[1-(cyclopropylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-1H-pyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-hydroxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(3-methoxypropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile?
The canonical SMILES for 4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N,N-dimethylbenzamide;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-3-(5-methoxypyrazin-2-yl)-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;5-[1-(cyclopropylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-1H-pyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-hydroxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(3-methoxypropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile is CC(C)CN1C(=O)N(c2cnc(C#N)nc2)CC12CCC(c1ccccc1)(N(C)C)CC2.CN(C)C(=O)c1ccc(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)cc1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc(C(N)=O)cc1)C(=O)N2CC1CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(=O)[nH]c1)C(=O)N2CC1(O)CCC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)nc1)C(=O)N2CC1CC1.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)nc1)C(=O)N2CCO.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cnc(C(F)(F)F)nc1)C(=O)N2CC1CCC1.CNC1(c2ccccc2)CCC2(CC1)CN(c1cnc(C#N)cc1C)C(=O)N2CC1CCC1.CNC1(c2ccccc2)CCC2(CC1)CN(c1cnc(OC)cn1)C(=O)N2CC1CCC1.COCCCN1C(=O)N(c2cnc(C#N)nc2)CC12CCC(c1ccccc1)(N(C)C)CC2.
What is the InChIKey of 4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N,N-dimethylbenzamide;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-3-(5-methoxypyrazin-2-yl)-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;5-[1-(cyclopropylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-1H-pyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-hydroxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(3-methoxypropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile?
The InChIKey is JWZSKRMFTVPYCU-UHFFFAOYSA-N. The full InChI is InChI=1S/C30H40N4O2.C28H36N4O2.C27H33N5O.C26H32F3N5O.C25H32N6O2.C25H30N6O.C25H32N6O.C25H33N5O3.C25H33N5O2.C23H28N6O2/c1-31(2)27(35)24-13-15-26(16-14-24)33-22-29(34(28(33)36)21-23-9-8-10-23)17-19-30(20-18-29,32(3)4)25-11-6-5-7-12-25;1-30(2)28(23-9-4-3-5-10-23)17-15-27(16-18-28)20-31(24-13-11-22(12-14-24)25(29)33)26(34)32(27)19-21-7-6-8-21;1-20-15-23(16-28)30-17-24(20)31-19-26(32(25(31)33)18-21-7-6-8-21)11-13-27(29-2,14-12-26)22-9-4-3-5-10-22;1-32(2)25(20-9-4-3-5-10-20)13-11-24(12-14-25)18-33(23(35)34(24)17-19-7-6-8-19)21-15-30-22(31-16-21)26(27,28)29;1-29(2)25(20-8-5-4-6-9-20)12-10-24(11-13-25)19-30(21-17-27-22(16-26)28-18-21)23(32)31(24)14-7-15-33-3;1-29(2)25(20-6-4-3-5-7-20)12-10-24(11-13-25)18-30(21-15-27-22(14-26)28-16-21)23(32)31(24)17-19-8-9-19;1-19(2)17-31-23(32)30(21-15-27-22(14-26)28-16-21)18-24(31)10-12-25(13-11-24,29(3)4)20-8-6-5-7-9-20;1-28(2)25(19-7-4-3-5-8-19)13-11-23(12-14-25)17-29(20-15-26-21(31)27-16-20)22(32)30(23)18-24(33)9-6-10-24;1-26-25(20-9-4-3-5-10-20)13-11-24(12-14-25)18-29(21-15-28-22(32-2)16-27-21)23(31)30(24)17-19-7-6-8-19;1-27(2)23(18-6-4-3-5-7-18)10-8-22(9-11-23)17-28(21(31)29(22)12-13-30)19-15-25-20(14-24)26-16-19/h5-7,11-16,23H,8-10,17-22H2,1-4H3;3-5,9-14,21H,6-8,15-20H2,1-2H3,(H2,29,33);3-5,9-10,15,17,21,29H,6-8,11-14,18-19H2,1-2H3;3-5,9-10,15-16,19H,6-8,11-14,17-18H2,1-2H3;4-6,8-9,17-18H,7,10-15,19H2,1-3H3;3-7,15-16,19H,8-13,17-18H2,1-2H3;5-9,15-16,19H,10-13,17-18H2,1-4H3;3-5,7-8,15-16,33H,6,9-14,17-18H2,1-2H3,(H,26,27,31);3-5,9-10,15-16,19,26H,6-8,11-14,17-18H2,1-2H3;3-7,15-16,30H,8-13,17H2,1-2H3.
What are the key properties of 4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N,N-dimethylbenzamide;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-3-(5-methoxypyrazin-2-yl)-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;5-[1-(cyclopropylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-1H-pyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-hydroxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(3-methoxypropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile?
4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N,N-dimethylbenzamide;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-3-(5-methoxypyrazin-2-yl)-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;5-[1-(cyclopropylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-1H-pyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-hydroxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(3-methoxypropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile has a molecular weight of 4499.82 g/mol, XLogP of 40.02, 55 rotatable bonds, 6 hydrogen bond donors, and 46 hydrogen bond acceptors.
Where does this data come from?
All data for 4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]benzamide;4-[1-(cyclobutylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N,N-dimethylbenzamide;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-3-(5-methoxypyrazin-2-yl)-8-(methylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[1-(cyclobutylmethyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;5-[1-(cyclopropylmethyl)-8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;8-(dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-oxo-1H-pyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-1-(2-hydroxyethyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(3-methoxypropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile;5-[8-(dimethylamino)-1-(2-methylpropyl)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carbonitrile is sourced from PubChem (CID 159048837), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).