5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(4-pyrrolidin-1-ylanilino)pyridine-2-carbohydrazide

C123H141ClF8N44O11 — CID 159056937

IUPAC5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(4-pyrrolidin-1-ylanilino)pyridine-2-carbohydrazide
SMILESCc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(N2CCN(CCO)CC2)c1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(Cl)cc(N3CCNCC3)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2ccc(N3CCCC3)cc2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2ccc(N3CCCCN3)cc2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2ccc(N3CCCN3)c(C(F)(F)F)c2)cn1
InChIInChI=1S/C27H34FN9O3.C24H27ClFN9O2.C24H25F4N9O2.C24H28FN9O2.C24H27FN8O2/c1-19-14-21(16-22(15-19)36-6-4-35(5-7-36)8-11-38)31-20-2-3-24(29-17-20)26(39)33-34-27-30-18-23(28)25(32-27)37-9-12-40-13-10-37;25-16-11-18(13-19(12-16)34-5-3-27-4-6-34)30-17-1-2-21(28-14-17)23(36)32-33-24-29-15-20(26)22(31-24)35-7-9-37-10-8-35;25-18-14-30-23(33-21(18)36-8-10-39-11-9-36)35-34-22(38)19-4-2-16(13-29-19)32-15-3-5-20(37-7-1-6-31-37)17(12-15)24(26,27)28;25-20-16-27-24(30-22(20)33-11-13-36-14-12-33)32-31-23(35)21-8-5-18(15-26-21)29-17-3-6-19(7-4-17)34-10-2-1-9-28-34;25-20-16-27-24(29-22(20)33-11-13-35-14-12-33)31-30-23(34)21-8-5-18(15-26-21)28-17-3-6-19(7-4-17)32-9-1-2-10-32/h2-3,14-18,31,38H,4-13H2,1H3,(H,33,39)(H,30,32,34);1-2,11-15,27,30H,3-10H2,(H,32,36)(H,29,31,33);2-5,12-14,31-32H,1,6-11H2,(H,34,38)(H,30,33,35);3-8,15-16,28-29H,1-2,9-14H2,(H,31,35)(H,27,30,32);3-8,15-16,28H,1-2,9-14H2,(H,30,34)(H,27,29,31)
InChIKeyJXYZYPZINJWZSA-UHFFFAOYSA-N
MW2599.21 g/mol
LogP12.66
Rot. Bonds37

About 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(4-pyrrolidin-1-ylanilino)pyridine-2-carbohydrazide

5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(4-pyrrolidin-1-ylanilino)pyridine-2-carbohydrazide (PubChem CID 159056937) has the molecular formula C123H141ClF8N44O11 and a molecular weight of 2599.21 g/mol. Its IUPAC name is 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(4-pyrrolidin-1-ylanilino)pyridine-2-carbohydrazide.

Molecular Properties

Compound Name5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(4-pyrrolidin-1-ylanilino)pyridine-2-carbohydrazide
PubChem CID159056937
Molecular FormulaC123H141ClF8N44O11
Molecular Weight2599.21 g/mol
Exact Mass2597.14
IUPAC Name5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(4-pyrrolidin-1-ylanilino)pyridine-2-carbohydrazide
SMILESCc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(N2CCN(CCO)CC2)c1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(Cl)cc(N3CCNCC3)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2ccc(N3CCCC3)cc2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2ccc(N3CCCCN3)cc2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2ccc(N3CCCN3)c(C(F)(F)F)c2)cn1
InChIInChI=1S/C27H34FN9O3.C24H27ClFN9O2.C24H25F4N9O2.C24H28FN9O2.C24H27FN8O2/c1-19-14-21(16-22(15-19)36-6-4-35(5-7-36)8-11-38)31-20-2-3-24(29-17-20)26(39)33-34-27-30-18-23(28)25(32-27)37-9-12-40-13-10-37;25-16-11-18(13-19(12-16)34-5-3-27-4-6-34)30-17-1-2-21(28-14-17)23(36)32-33-24-29-15-20(26)22(31-24)35-7-9-37-10-8-35;25-18-14-30-23(33-21(18)36-8-10-39-11-9-36)35-34-22(38)19-4-2-16(13-29-19)32-15-3-5-20(37-7-1-6-31-37)17(12-15)24(26,27)28;25-20-16-27-24(30-22(20)33-11-13-36-14-12-33)32-31-23(35)21-8-5-18(15-26-21)29-17-3-6-19(7-4-17)34-10-2-1-9-28-34;25-20-16-27-24(29-22(20)33-11-13-35-14-12-33)31-30-23(34)21-8-5-18(15-26-21)28-17-3-6-19(7-4-17)32-9-1-2-10-32/h2-3,14-18,31,38H,4-13H2,1H3,(H,33,39)(H,30,32,34);1-2,11-15,27,30H,3-10H2,(H,32,36)(H,29,31,33);2-5,12-14,31-32H,1,6-11H2,(H,34,38)(H,30,33,35);3-8,15-16,28-29H,1-2,9-14H2,(H,31,35)(H,27,30,32);3-8,15-16,28H,1-2,9-14H2,(H,30,34)(H,27,29,31)
InChIKeyJXYZYPZINJWZSA-UHFFFAOYSA-N
XLogP12.66
TPSA597.26 Ų
H-Bond Donors19
H-Bond Acceptors50
Rotatable Bonds37
Heavy Atoms187
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002599.21
LogP ≤ 512.66
H-Bond Donors ≤ 519
H-Bond Acceptors ≤ 1050

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'anil_di_alk_A(478)', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}

Analyze 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(4-pyrrolidin-1-ylanilino)pyridine-2-carbohydrazide with MolForge

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Related Compounds

5-(3-chloro-5-pyridin-3-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide
CID 58876735
5-(3-chloro-5-pyrimidin-4-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide
CID 58876768
5-(2-chloro-6-methyl-4-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide
CID 58877238
N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide
CID 58877258
5-(3-chloro-5-pyrimidin-5-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide
CID 58877306
5-(3-chloro-5-pyrimidin-2-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide
CID 58877326
5-[3-[5-[4-[2-[2-[5-(3-chloro-5-pyrazolidin-1-ylanilino)pyridine-2-carbonyl]hydrazinyl]-5-fluoropyrimidin-4-yl]morpholin-2-yl]diazinan-1-yl]anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide
CID 129106565
5-[2-chloro-4-[(dimethylamino)methyl]anilino]-N'-[5-fluoro-4-[2-[[[3-[[6-[[(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)amino]carbamoyl]pyridin-3-yl]amino]-5-(trifluoromethyl)phenyl]methyl-methylamino]methyl]morpholin-4-yl]pyrimidin-2-yl]pyridine-2-carbohydrazide
CID 129106567
N'-[5-fluoro-4-[2-[1-[4-[[6-[[(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)amino]carbamoyl]pyridin-3-yl]amino]-2-(trifluoromethyl)phenyl]pyrazolidin-3-yl]morpholin-4-yl]pyrimidin-2-yl]-5-(4-pyrrolidin-1-ylanilino)pyridine-2-carbohydrazide
CID 129106607
N'-[4-[2-[2-[3-chloro-5-[[6-[[(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)amino]carbamoyl]pyridin-3-yl]amino]phenyl]pyrazolidin-3-yl]morpholin-4-yl]-5-fluoropyrimidin-2-yl]-5-[3-pyrrolidin-1-yl-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide
CID 130197436
N'-[5-fluoro-4-[2-[2-[3-[[6-[[(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)amino]carbamoyl]pyridin-3-yl]amino]-5-(trifluoromethyl)phenyl]-5-methylpyrazolidin-3-yl]morpholin-4-yl]pyrimidin-2-yl]-5-[3-(5-methylpyrazolidin-1-yl)-5-(trifluoromethyl)anilino]pyridine-2-carbohydrazide
CID 130197455
5-[3-[[[4-[2-[2-[5-[3-[(dimethylamino)methyl]-5-(trifluoromethyl)anilino]pyridine-2-carbonyl]hydrazinyl]-5-fluoropyrimidin-4-yl]morpholin-2-yl]methyl-methylamino]methyl]anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide
CID 146244806

Frequently Asked Questions

What is the IUPAC name of 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(4-pyrrolidin-1-ylanilino)pyridine-2-carbohydrazide?
The IUPAC name of 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(4-pyrrolidin-1-ylanilino)pyridine-2-carbohydrazide (CID 159056937) is 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(4-pyrrolidin-1-ylanilino)pyridine-2-carbohydrazide.
What is the SMILES notation for 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(4-pyrrolidin-1-ylanilino)pyridine-2-carbohydrazide?
The canonical SMILES for 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(4-pyrrolidin-1-ylanilino)pyridine-2-carbohydrazide is Cc1cc(Nc2ccc(C(=O)NNc3ncc(F)c(N4CCOCC4)n3)nc2)cc(N2CCN(CCO)CC2)c1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2cc(Cl)cc(N3CCNCC3)c2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2ccc(N3CCCC3)cc2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2ccc(N3CCCCN3)cc2)cn1.O=C(NNc1ncc(F)c(N2CCOCC2)n1)c1ccc(Nc2ccc(N3CCCN3)c(C(F)(F)F)c2)cn1.
What is the InChIKey of 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(4-pyrrolidin-1-ylanilino)pyridine-2-carbohydrazide?
The InChIKey is JXYZYPZINJWZSA-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H34FN9O3.C24H27ClFN9O2.C24H25F4N9O2.C24H28FN9O2.C24H27FN8O2/c1-19-14-21(16-22(15-19)36-6-4-35(5-7-36)8-11-38)31-20-2-3-24(29-17-20)26(39)33-34-27-30-18-23(28)25(32-27)37-9-12-40-13-10-37;25-16-11-18(13-19(12-16)34-5-3-27-4-6-34)30-17-1-2-21(28-14-17)23(36)32-33-24-29-15-20(26)22(31-24)35-7-9-37-10-8-35;25-18-14-30-23(33-21(18)36-8-10-39-11-9-36)35-34-22(38)19-4-2-16(13-29-19)32-15-3-5-20(37-7-1-6-31-37)17(12-15)24(26,27)28;25-20-16-27-24(30-22(20)33-11-13-36-14-12-33)32-31-23(35)21-8-5-18(15-26-21)29-17-3-6-19(7-4-17)34-10-2-1-9-28-34;25-20-16-27-24(29-22(20)33-11-13-35-14-12-33)31-30-23(34)21-8-5-18(15-26-21)28-17-3-6-19(7-4-17)32-9-1-2-10-32/h2-3,14-18,31,38H,4-13H2,1H3,(H,33,39)(H,30,32,34);1-2,11-15,27,30H,3-10H2,(H,32,36)(H,29,31,33);2-5,12-14,31-32H,1,6-11H2,(H,34,38)(H,30,33,35);3-8,15-16,28-29H,1-2,9-14H2,(H,31,35)(H,27,30,32);3-8,15-16,28H,1-2,9-14H2,(H,30,34)(H,27,29,31).
What are the key properties of 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(4-pyrrolidin-1-ylanilino)pyridine-2-carbohydrazide?
5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(4-pyrrolidin-1-ylanilino)pyridine-2-carbohydrazide has a molecular weight of 2599.21 g/mol, XLogP of 12.66, 37 rotatable bonds, 19 hydrogen bond donors, and 50 hydrogen bond acceptors.
Where does this data come from?
All data for 5-(3-chloro-5-piperazin-1-ylanilino)-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;5-[4-(diazinan-1-yl)anilino]-N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-5-methylanilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-[4-pyrazolidin-1-yl-3-(trifluoromethyl)anilino]pyridine-2-carbohydrazide;N'-(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)-5-(4-pyrrolidin-1-ylanilino)pyridine-2-carbohydrazide is sourced from PubChem (CID 159056937), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).