N-[1-[1-[6-[2-(3-chloro-4-methylphenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-(2,3-dihydro-1H-inden-2-yl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpiperidin-4-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide

C173H246Cl2F3N33O18S6 — CID 159062595

IUPACN-[1-[1-[6-[2-(3-chloro-4-methylphenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-(2,3-dihydro-1H-inden-2-yl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpiperidin-4-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide
SMILESCc1c(CCC2CCN(c3ccccc3)C2)ncnc1C(=O)N1CCC(N2CCC(N(C)S(C)(=O)=O)CC2)CC1.Cc1c(CCC2CCN(c3ccccc3)C2)ncnc1C(=O)N1CCC(N2CCC(NS(C)(=O)=O)CC2)CC1.Cc1c(CCC2CCN(c3ccccc3)CC2)ncnc1C(=O)N1CCC(N2CCC(N(C)S(C)(=O)=O)CC2)CC1.Cc1c(CCC2Cc3ccccc3C2)ncnc1C(=O)N1CCC(N2CCC(N(C)S(C)(=O)=O)CC2)CC1.Cc1c(CCc2ccc(C(F)(F)F)c(Cl)c2)ncnc1C(=O)N1CCC(N2CCC(N(C)S(C)(=O)=O)CC2)CC1.Cc1ccc(CCc2ncnc(C(=O)N3CCC(N4CCC(N(C)S(C)(=O)=O)CC4)CC3)c2C)cc1Cl
InChIInChI=1S/C31H46N6O3S.C30H44N6O3S.C29H42N6O3S.C29H41N5O3S.C27H35ClF3N5O3S.C27H38ClN5O3S/c1-24-29(10-9-25-11-17-35(18-12-25)27-7-5-4-6-8-27)32-23-33-30(24)31(38)37-21-15-28(16-22-37)36-19-13-26(14-20-36)34(2)41(3,39)40;1-23-28(10-9-24-11-16-36(21-24)26-7-5-4-6-8-26)31-22-32-29(23)30(37)35-19-14-27(15-20-35)34-17-12-25(13-18-34)33(2)40(3,38)39;1-22-27(9-8-23-10-15-35(20-23)25-6-4-3-5-7-25)30-21-31-28(22)29(36)34-18-13-26(14-19-34)33-16-11-24(12-17-33)32-39(2,37)38;1-21-27(9-8-22-18-23-6-4-5-7-24(23)19-22)30-20-31-28(21)29(35)34-16-12-26(13-17-34)33-14-10-25(11-15-33)32(2)38(3,36)37;1-18-24(7-5-19-4-6-22(23(28)16-19)27(29,30)31)32-17-33-25(18)26(37)36-14-10-21(11-15-36)35-12-8-20(9-13-35)34(2)40(3,38)39;1-19-5-6-21(17-24(19)28)7-8-25-20(2)26(30-18-29-25)27(34)33-15-11-23(12-16-33)32-13-9-22(10-14-32)31(3)37(4,35)36/h4-8,23,25-26,28H,9-22H2,1-3H3;4-8,22,24-25,27H,9-21H2,1-3H3;3-7,21,23-24,26,32H,8-20H2,1-2H3;4-7,20,22,25-26H,8-19H2,1-3H3;4,6,16-17,20-21H,5,7-15H2,1-3H3;5-6,17-18,22-23H,7-16H2,1-4H3
InChIKeyJYQRWRKITGIZSI-UHFFFAOYSA-N
MW3396.39 g/mol
LogP20.45
Rot. Bonds45

About N-[1-[1-[6-[2-(3-chloro-4-methylphenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-(2,3-dihydro-1H-inden-2-yl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpiperidin-4-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide

N-[1-[1-[6-[2-(3-chloro-4-methylphenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-(2,3-dihydro-1H-inden-2-yl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpiperidin-4-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide (PubChem CID 159062595) has the molecular formula C173H246Cl2F3N33O18S6 and a molecular weight of 3396.39 g/mol. Its IUPAC name is N-[1-[1-[6-[2-(3-chloro-4-methylphenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-(2,3-dihydro-1H-inden-2-yl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpiperidin-4-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide.

Molecular Properties

Compound NameN-[1-[1-[6-[2-(3-chloro-4-methylphenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-(2,3-dihydro-1H-inden-2-yl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpiperidin-4-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide
PubChem CID159062595
Molecular FormulaC173H246Cl2F3N33O18S6
Molecular Weight3396.39 g/mol
Exact Mass3392.70
IUPAC NameN-[1-[1-[6-[2-(3-chloro-4-methylphenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-(2,3-dihydro-1H-inden-2-yl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpiperidin-4-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide
SMILESCc1c(CCC2CCN(c3ccccc3)C2)ncnc1C(=O)N1CCC(N2CCC(N(C)S(C)(=O)=O)CC2)CC1.Cc1c(CCC2CCN(c3ccccc3)C2)ncnc1C(=O)N1CCC(N2CCC(NS(C)(=O)=O)CC2)CC1.Cc1c(CCC2CCN(c3ccccc3)CC2)ncnc1C(=O)N1CCC(N2CCC(N(C)S(C)(=O)=O)CC2)CC1.Cc1c(CCC2Cc3ccccc3C2)ncnc1C(=O)N1CCC(N2CCC(N(C)S(C)(=O)=O)CC2)CC1.Cc1c(CCc2ccc(C(F)(F)F)c(Cl)c2)ncnc1C(=O)N1CCC(N2CCC(N(C)S(C)(=O)=O)CC2)CC1.Cc1ccc(CCc2ncnc(C(=O)N3CCC(N4CCC(N(C)S(C)(=O)=O)CC4)CC3)c2C)cc1Cl
InChIInChI=1S/C31H46N6O3S.C30H44N6O3S.C29H42N6O3S.C29H41N5O3S.C27H35ClF3N5O3S.C27H38ClN5O3S/c1-24-29(10-9-25-11-17-35(18-12-25)27-7-5-4-6-8-27)32-23-33-30(24)31(38)37-21-15-28(16-22-37)36-19-13-26(14-20-36)34(2)41(3,39)40;1-23-28(10-9-24-11-16-36(21-24)26-7-5-4-6-8-26)31-22-32-29(23)30(37)35-19-14-27(15-20-35)34-17-12-25(13-18-34)33(2)40(3,38)39;1-22-27(9-8-23-10-15-35(20-23)25-6-4-3-5-7-25)30-21-31-28(22)29(36)34-18-13-26(14-19-34)33-16-11-24(12-17-33)32-39(2,37)38;1-21-27(9-8-22-18-23-6-4-5-7-24(23)19-22)30-20-31-28(21)29(35)34-16-12-26(13-17-34)33-14-10-25(11-15-33)32(2)38(3,36)37;1-18-24(7-5-19-4-6-22(23(28)16-19)27(29,30)31)32-17-33-25(18)26(37)36-14-10-21(11-15-36)35-12-8-20(9-13-35)34(2)40(3,38)39;1-19-5-6-21(17-24(19)28)7-8-25-20(2)26(30-18-29-25)27(34)33-15-11-23(12-16-33)32-13-9-22(10-14-32)31(3)37(4,35)36/h4-8,23,25-26,28H,9-22H2,1-3H3;4-8,22,24-25,27H,9-21H2,1-3H3;3-7,21,23-24,26,32H,8-20H2,1-2H3;4-7,20,22,25-26H,8-19H2,1-3H3;4,6,16-17,20-21H,5,7-15H2,1-3H3;5-6,17-18,22-23H,7-16H2,1-4H3
InChIKeyJYQRWRKITGIZSI-UHFFFAOYSA-N
XLogP20.45
TPSA538.77 Ų
H-Bond Donors1
H-Bond Acceptors39
Rotatable Bonds45
Heavy Atoms235
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5003396.39
LogP ≤ 520.45
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 1039

Analyze N-[1-[1-[6-[2-(3-chloro-4-methylphenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-(2,3-dihydro-1H-inden-2-yl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpiperidin-4-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-[1-[1-[6-[2-(4-chloro-3-fluorophenyl)ethyl]-2,5-dimethylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;(3R)-1-[1-[6-[2-(4-chloro-3-fluorophenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]-N-methylpyrrolidine-3-carboxamide;N-[1-[1-[6-[2-(4-chloro-3-fluorophenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-[1-[1-[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-2,5-dimethylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;(3R)-1-[1-[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]-N-methylpyrrolidine-3-carboxamide
CID 157809697
N-[1-[1-[6-[(3-chloro-4-methylphenyl)methylamino]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylethanesulfonamide;[6-(2,3-dihydro-1H-inden-2-ylmethylamino)-5-methylpyrimidin-4-yl]-[4-(4-hydroxypiperidin-1-yl)piperidin-1-yl]methanone;[6-[(3,4-dimethylphenyl)methylamino]-5-methylpyrimidin-4-yl]-[4-(4-hydroxypiperidin-1-yl)piperidin-1-yl]methanone;[6-[[2-fluoro-4-(trifluoromethyl)phenyl]methylamino]-5-methylpyrimidin-4-yl]-[4-(4-hydroxypiperidin-1-yl)piperidin-1-yl]methanone;[4-(4-hydroxypiperidin-1-yl)piperidin-1-yl]-[5-methyl-6-[(1-phenylpyrrolidin-3-yl)methylamino]pyrimidin-4-yl]methanone
CID 158350305
N-[1-[1-[6-[4-(3-chlorophenyl)piperidin-1-yl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[4-(4-chlorophenyl)piperidin-1-yl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-(4-phenylpiperidin-1-yl)pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide
CID 159157731
N-[1-[1-[6-[(3-chloro-4-methylphenyl)methylamino]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylethanesulfonamide;[6-(2,3-dihydro-1H-inden-2-ylmethylamino)-5-methylpyrimidin-4-yl]-[4-(4-hydroxypiperidin-1-yl)piperidin-1-yl]methanone;[6-[(3,4-dimethylphenyl)methylamino]-5-methylpyrimidin-4-yl]-[4-(4-hydroxypiperidin-1-yl)piperidin-1-yl]methanone;[6-[[2-fluoro-4-(trifluoromethyl)phenyl]methylamino]-5-methylpyrimidin-4-yl]-[4-(4-hydroxypiperidin-1-yl)piperidin-1-yl]methanone;[4-(4-hydroxypiperidin-1-yl)piperidin-1-yl]-[5-methyl-6-[(4-phenylcyclohexyl)methyl]pyrimidin-4-yl]methanone;[4-(4-hydroxypiperidin-1-yl)piperidin-1-yl]-[5-methyl-6-[(1-phenylpyrrolidin-3-yl)methylamino]pyrimidin-4-yl]methanone
CID 159691551
N-[1-[1-[6-[2-(4-chloro-3-fluorophenyl)ethyl]-2,5-dimethylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;(3R)-1-[1-[6-[2-(4-chloro-3-fluorophenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]-N-methylpyrrolidine-3-carboxamide;N-[1-[1-[6-[2-(4-chloro-3-fluorophenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-[1-[1-[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-2,5-dimethylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;(3R)-1-[1-[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]-N-methylpyrrolidine-3-carboxamide;N-[1-[1-[2,5-dimethyl-6-[(3-phenylcyclohexyl)methyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide
CID 159985774
[6-[2-(4-chloro-3-fluorophenyl)ethyl]-5-methylpyrimidin-4-yl]-(4-morpholin-4-ylpiperidin-1-yl)methanone;[6-[2-(3-chloro-4-methylphenyl)ethyl]-5-methylpyrimidin-4-yl]-(4-morpholin-4-ylpiperidin-1-yl)methanone;[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-5-methylpyrimidin-4-yl]-(4-morpholin-4-ylpiperidin-1-yl)methanone;[6-[2-(3,4-difluorophenyl)ethyl]-5-methylpyrimidin-4-yl]-(4-morpholin-4-ylpiperidin-1-yl)methanone;[6-[2-(2,3-dihydro-1H-inden-2-yl)ethyl]-5-methylpyrimidin-4-yl]-(4-morpholin-4-ylpiperidin-1-yl)methanone;[6-[2-(3-fluoro-4-methylphenyl)ethyl]-5-methylpyrimidin-4-yl]-(4-morpholin-4-ylpiperidin-1-yl)methanone;[5-methyl-6-[(1-phenylpyrrolidin-3-yl)methylamino]pyrimidin-4-yl]-(4-morpholin-4-ylpiperidin-1-yl)methanone
CID 160031761
6-[5-(1-acetylpiperidin-2-yl)-3-chloro-2-pyridinyl]-2-[4-[(1-methylpyrrolidin-3-yl)amino]anilino]-8-propan-2-ylpyrido[2,3-d]pyrimidin-7-one;6-[2-(1-acetylpiperidin-4-yl)-4-methylphenyl]-8-(1-methylsulfonylpiperidin-4-yl)-2-[4-(piperidin-3-ylamino)anilino]pyrido[2,3-d]pyrimidin-7-one;6-[2-(1-acetylpyrrolidin-2-yl)-4-methyl-3H-pyrrol-5-yl]-2-(3-methyl-4-piperazin-1-ylanilino)-8-[[2-(trifluoromethyl)phenyl]methyl]pyrido[2,3-d]pyrimidin-7-one;6-[2-chloro-4-(1-prop-1-en-2-ylpiperidin-3-yl)phenyl]-8-ethyl-2-[4-(piperidin-4-ylamino)anilino]pyrido[2,3-d]pyrimidin-7-one
CID 161483600
N-[1-[1-[6-[2-(4-tert-butylphenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylethanesulfonamide;N-[1-[1-[6-[2-(3,4-dichlorophenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylethanesulfonamide;N-[1-[1-[6-[3-(3,4-dichlorophenyl)propyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylethanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[(1-phenylpiperidin-3-yl)methylamino]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]ethanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[(4-propan-2-ylphenyl)methylamino]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]ethanesulfonamide
CID 158348828
N-[1-[1-[6-[2-(4-tert-butylphenyl)ethyl]-2-methoxy-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-[3-(4-chlorophenyl)cyclopentyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-(cyclohexylmethylamino)-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(3-phenylcyclopentyl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(4-propan-2-ylcyclohexyl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide
CID 159611273
N-methyl-N-[1-[1-[5-methyl-6-[2-[(1R,3S)-3-phenylcyclohexyl]ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-[(1S,3S)-3-phenylcyclohexyl]ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[[(3S)-1-phenylpyrrolidin-3-yl]methylamino]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-(1,2,3,4-tetrahydronaphthalen-1-ylmethylamino)pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide
CID 160254192
1-[1-[6-[2-[3-(4-chlorophenyl)cyclohexyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]-N-methylpiperidine-4-carboxamide;N-[1-[1-[6-[[3-(4-chlorophenyl)cyclohexyl]methylamino]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-[1-[1-[6-[[3-(4-chlorophenyl)cyclohexyl]methylamino]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;1-[1-[6-[2-[3-(4-fluorophenyl)cyclohexyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]-N-methylpiperidine-4-carboxamide;N-[1-[1-[6-[[3-(4-fluorophenyl)cyclohexyl]methylamino]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide
CID 160878656
N-[1-[1-[6-[2-(3,4-dichlorophenyl)ethyl]-2,5-dimethylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-[1-[1-[6-(2,3-dihydro-1H-inden-2-ylmethylamino)-2,5-dimethylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[2,5-dimethyl-6-[2-(1-phenylpiperidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[2,5-dimethyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[2,5-dimethyl-6-[[(3S)-1-phenylpyrrolidin-3-yl]methylamino]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide
CID 161760189

Frequently Asked Questions

What is the IUPAC name of N-[1-[1-[6-[2-(3-chloro-4-methylphenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-(2,3-dihydro-1H-inden-2-yl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpiperidin-4-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide?
The IUPAC name of N-[1-[1-[6-[2-(3-chloro-4-methylphenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-(2,3-dihydro-1H-inden-2-yl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpiperidin-4-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide (CID 159062595) is N-[1-[1-[6-[2-(3-chloro-4-methylphenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-(2,3-dihydro-1H-inden-2-yl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpiperidin-4-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide.
What is the SMILES notation for N-[1-[1-[6-[2-(3-chloro-4-methylphenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-(2,3-dihydro-1H-inden-2-yl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpiperidin-4-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide?
The canonical SMILES for N-[1-[1-[6-[2-(3-chloro-4-methylphenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-(2,3-dihydro-1H-inden-2-yl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpiperidin-4-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide is Cc1c(CCC2CCN(c3ccccc3)C2)ncnc1C(=O)N1CCC(N2CCC(N(C)S(C)(=O)=O)CC2)CC1.Cc1c(CCC2CCN(c3ccccc3)C2)ncnc1C(=O)N1CCC(N2CCC(NS(C)(=O)=O)CC2)CC1.Cc1c(CCC2CCN(c3ccccc3)CC2)ncnc1C(=O)N1CCC(N2CCC(N(C)S(C)(=O)=O)CC2)CC1.Cc1c(CCC2Cc3ccccc3C2)ncnc1C(=O)N1CCC(N2CCC(N(C)S(C)(=O)=O)CC2)CC1.Cc1c(CCc2ccc(C(F)(F)F)c(Cl)c2)ncnc1C(=O)N1CCC(N2CCC(N(C)S(C)(=O)=O)CC2)CC1.Cc1ccc(CCc2ncnc(C(=O)N3CCC(N4CCC(N(C)S(C)(=O)=O)CC4)CC3)c2C)cc1Cl.
What is the InChIKey of N-[1-[1-[6-[2-(3-chloro-4-methylphenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-(2,3-dihydro-1H-inden-2-yl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpiperidin-4-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide?
The InChIKey is JYQRWRKITGIZSI-UHFFFAOYSA-N. The full InChI is InChI=1S/C31H46N6O3S.C30H44N6O3S.C29H42N6O3S.C29H41N5O3S.C27H35ClF3N5O3S.C27H38ClN5O3S/c1-24-29(10-9-25-11-17-35(18-12-25)27-7-5-4-6-8-27)32-23-33-30(24)31(38)37-21-15-28(16-22-37)36-19-13-26(14-20-36)34(2)41(3,39)40;1-23-28(10-9-24-11-16-36(21-24)26-7-5-4-6-8-26)31-22-32-29(23)30(37)35-19-14-27(15-20-35)34-17-12-25(13-18-34)33(2)40(3,38)39;1-22-27(9-8-23-10-15-35(20-23)25-6-4-3-5-7-25)30-21-31-28(22)29(36)34-18-13-26(14-19-34)33-16-11-24(12-17-33)32-39(2,37)38;1-21-27(9-8-22-18-23-6-4-5-7-24(23)19-22)30-20-31-28(21)29(35)34-16-12-26(13-17-34)33-14-10-25(11-15-33)32(2)38(3,36)37;1-18-24(7-5-19-4-6-22(23(28)16-19)27(29,30)31)32-17-33-25(18)26(37)36-14-10-21(11-15-36)35-12-8-20(9-13-35)34(2)40(3,38)39;1-19-5-6-21(17-24(19)28)7-8-25-20(2)26(30-18-29-25)27(34)33-15-11-23(12-16-33)32-13-9-22(10-14-32)31(3)37(4,35)36/h4-8,23,25-26,28H,9-22H2,1-3H3;4-8,22,24-25,27H,9-21H2,1-3H3;3-7,21,23-24,26,32H,8-20H2,1-2H3;4-7,20,22,25-26H,8-19H2,1-3H3;4,6,16-17,20-21H,5,7-15H2,1-3H3;5-6,17-18,22-23H,7-16H2,1-4H3.
What are the key properties of N-[1-[1-[6-[2-(3-chloro-4-methylphenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-(2,3-dihydro-1H-inden-2-yl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpiperidin-4-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide?
N-[1-[1-[6-[2-(3-chloro-4-methylphenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-(2,3-dihydro-1H-inden-2-yl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpiperidin-4-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide has a molecular weight of 3396.39 g/mol, XLogP of 20.45, 45 rotatable bonds, 1 hydrogen bond donors, and 39 hydrogen bond acceptors.
Where does this data come from?
All data for N-[1-[1-[6-[2-(3-chloro-4-methylphenyl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-[1-[1-[6-[2-(2,3-dihydro-1H-inden-2-yl)ethyl]-5-methylpyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]-N-methylmethanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpiperidin-4-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-methyl-N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide;N-[1-[1-[5-methyl-6-[2-(1-phenylpyrrolidin-3-yl)ethyl]pyrimidine-4-carbonyl]piperidin-4-yl]piperidin-4-yl]methanesulfonamide is sourced from PubChem (CID 159062595), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).