N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-fluorobenzamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-methoxybenzamide;2-chloro-N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]benzamide;2-chloro-N-[6-fluoro-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-4-methylbenzamide

C125H92Cl3F24N29O11 — CID 159066939

About N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-fluorobenzamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-methoxybenzamide;2-chloro-N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]benzamide;2-chloro-N-[6-fluoro-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-4-methylbenzamide

N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-fluorobenzamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-methoxybenzamide;2-chloro-N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]benzamide;2-chloro-N-[6-fluoro-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-4-methylbenzamide (PubChem CID 159066939) has the molecular formula C125H92Cl3F24N29O11 and a molecular weight of 2738.61 g/mol. Its IUPAC name is N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-fluorobenzamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-methoxybenzamide;2-chloro-N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]benzamide;2-chloro-N-[6-fluoro-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-4-methylbenzamide.

Molecular Properties

• Compound Name: N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-fluorobenzamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-methoxybenzamide;2-chloro-N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]benzamide;2-chloro-N-[6-fluoro-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-4-methylbenzamide
• PubChem CID: 159066939
• Molecular Formula: C125H92Cl3F24N29O11
• Molecular Weight: 2738.61 g/mol
• Exact Mass: 2735.62
• IUPAC Name: N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-fluorobenzamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-methoxybenzamide;2-chloro-N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]benzamide;2-chloro-N-[6-fluoro-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-4-methylbenzamide
• SMILES: COc1ccccc1C(=O)Nc1ccc(-c2cc(C(F)(F)F)nn2C)c(N)n1.Cc1ccc(C(=O)Nc2ncc(-c3cc(C(F)(F)F)nn3C)cc2O)c(F)c1.Cn1c(-c2ccc(NC(=O)c3ccccc3Cl)nc2F)cc2ccccc21.Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)c2ccccc2Cl)nc1F.Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)c2ccccc2F)nc1N.Cn1nc(C(F)(F)F)cc1-c1cnc(NC(=O)c2c(F)cccc2F)c(O)c1.Cn1nc(C(F)(F)F)cc1-c1cnc(NC(=O)c2ccccc2Cl)c(O)c1
• InChI: InChI=1S/C21H15ClFN3O.C18H14F4N4O2.C18H16F3N5O2.C17H11ClF4N4O.C17H12ClF3N4O2.C17H11F5N4O2.C17H13F4N5O/c1-26-17-9-5-2-6-13(17)12-18(26)15-10-11-19(24-20(15)23)25-21(27)14-7-3-4-8-16(14)22;1-9-3-4-11(12(19)5-9)17(28)24-16-14(27)6-10(8-23-16)13-7-15(18(20,21)22)25-26(13)2;1-26-12(9-14(25-26)18(19,20)21)10-7-8-15(23-16(10)22)24-17(27)11-5-3-4-6-13(11)28-2;1-26-12(8-13(25-26)17(20,21)22)10-6-7-14(23-15(10)19)24-16(27)9-4-2-3-5-11(9)18;1-25-12(7-14(24-25)17(19,20)21)9-6-13(26)15(22-8-9)23-16(27)10-4-2-3-5-11(10)18;1-26-11(6-13(25-26)17(20,21)22)8-5-12(27)15(23-7-8)24-16(28)14-9(18)3-2-4-10(14)19;1-26-12(8-13(25-26)17(19,20)21)10-6-7-14(23-15(10)22)24-16(27)9-4-2-3-5-11(9)18/h2-12H,1H3,(H,24,25,27);3-8,27H,1-2H3,(H,23,24,28);3-9H,1-2H3,(H3,22,23,24,27);2-8H,1H3,(H,23,24,27);2-8,26H,1H3,(H,22,23,27);2-7,27H,1H3,(H,23,24,28);2-8H,1H3,(H3,22,23,24,27)
• InChIKey: JZEBTMKAOXTDOB-UHFFFAOYSA-N
• XLogP: 28.40
• TPSA: 527.74 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 33
• Rotatable Bonds: 22
• Heavy Atoms: 192
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2738.61
LogP ≤ 5	28.40
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	33

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-fluorobenzamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-methoxybenzamide;2-chloro-N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]benzamide;2-chloro-N-[6-fluoro-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-4-methylbenzamide?

The IUPAC name of N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-fluorobenzamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-methoxybenzamide;2-chloro-N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]benzamide;2-chloro-N-[6-fluoro-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-4-methylbenzamide (CID 159066939) is N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-fluorobenzamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-methoxybenzamide;2-chloro-N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]benzamide;2-chloro-N-[6-fluoro-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-4-methylbenzamide.

What is the SMILES notation for N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-fluorobenzamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-methoxybenzamide;2-chloro-N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]benzamide;2-chloro-N-[6-fluoro-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-4-methylbenzamide?

The canonical SMILES for N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-fluorobenzamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-methoxybenzamide;2-chloro-N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]benzamide;2-chloro-N-[6-fluoro-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-4-methylbenzamide is COc1ccccc1C(=O)Nc1ccc(-c2cc(C(F)(F)F)nn2C)c(N)n1.Cc1ccc(C(=O)Nc2ncc(-c3cc(C(F)(F)F)nn3C)cc2O)c(F)c1.Cn1c(-c2ccc(NC(=O)c3ccccc3Cl)nc2F)cc2ccccc21.Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)c2ccccc2Cl)nc1F.Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)c2ccccc2F)nc1N.Cn1nc(C(F)(F)F)cc1-c1cnc(NC(=O)c2c(F)cccc2F)c(O)c1.Cn1nc(C(F)(F)F)cc1-c1cnc(NC(=O)c2ccccc2Cl)c(O)c1.

What is the InChIKey of N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-fluorobenzamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-methoxybenzamide;2-chloro-N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]benzamide;2-chloro-N-[6-fluoro-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-4-methylbenzamide?

The InChIKey is JZEBTMKAOXTDOB-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H15ClFN3O.C18H14F4N4O2.C18H16F3N5O2.C17H11ClF4N4O.C17H12ClF3N4O2.C17H11F5N4O2.C17H13F4N5O/c1-26-17-9-5-2-6-13(17)12-18(26)15-10-11-19(24-20(15)23)25-21(27)14-7-3-4-8-16(14)22;1-9-3-4-11(12(19)5-9)17(28)24-16-14(27)6-10(8-23-16)13-7-15(18(20,21)22)25-26(13)2;1-26-12(9-14(25-26)18(19,20)21)10-7-8-15(23-16(10)22)24-17(27)11-5-3-4-6-13(11)28-2;1-26-12(8-13(25-26)17(20,21)22)10-6-7-14(23-15(10)19)24-16(27)9-4-2-3-5-11(9)18;1-25-12(7-14(24-25)17(19,20)21)9-6-13(26)15(22-8-9)23-16(27)10-4-2-3-5-11(10)18;1-26-11(6-13(25-26)17(20,21)22)8-5-12(27)15(23-7-8)24-16(28)14-9(18)3-2-4-10(14)19;1-26-12(8-13(25-26)17(19,20)21)10-6-7-14(23-15(10)22)24-16(27)9-4-2-3-5-11(9)18/h2-12H,1H3,(H,24,25,27);3-8,27H,1-2H3,(H,23,24,28);3-9H,1-2H3,(H3,22,23,24,27);2-8H,1H3,(H,23,24,27);2-8,26H,1H3,(H,22,23,27);2-7,27H,1H3,(H,23,24,28);2-8H,1H3,(H3,22,23,24,27).

What are the key properties of N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-fluorobenzamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-methoxybenzamide;2-chloro-N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]benzamide;2-chloro-N-[6-fluoro-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-4-methylbenzamide?

N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-fluorobenzamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-methoxybenzamide;2-chloro-N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]benzamide;2-chloro-N-[6-fluoro-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-4-methylbenzamide has a molecular weight of 2738.61 g/mol, XLogP of 28.40, 22 rotatable bonds, 12 hydrogen bond donors, and 33 hydrogen bond acceptors.

Where does this data come from?

All data for N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-fluorobenzamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-methoxybenzamide;2-chloro-N-[6-fluoro-5-(1-methylindol-2-yl)-2-pyridinyl]benzamide;2-chloro-N-[6-fluoro-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-chloro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2,6-difluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]benzamide;2-fluoro-N-[3-hydroxy-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-4-methylbenzamide is sourced from PubChem (CID 159066939), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).