1-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;(2S)-2-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-1-ol;2-[[4-amino-5-[(2-chloro-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-2-yl]amino]butan-1-ol;1-[[2-amino-5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-methoxyethyl)pyrimidine-2,4-diamine;[5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]hydrazine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-piperidin-1-ylethyl)pyrimidine-2,4-diamine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-pyrrolidin-1-ylethyl)pyrimidine-2,4-diamine;5-[[5-(cyclopenten-1-yl)-2-methoxy-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(5-cyclopentyl-2-methoxy-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[[2-[(dimethylamino)methyl]-5-propan-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[[2-(ethylamino)-5-prop-1-en-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-N,2-dimethylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methyl-N-propan-2-ylpyrimidin-4-amine;2-[[5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]amino]ethanol;5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[(2-methoxy-5-morpholin-4-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;2-methyl-5-[(2-methylsulfanyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-amine

C289H364Br6ClN85O28S — CID 159070759

IUPAC1-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;(2S)-2-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-1-ol;2-[[4-amino-5-[(2-chloro-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-2-yl]amino]butan-1-ol;1-[[2-amino-5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-methoxyethyl)pyrimidine-2,4-diamine;[5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]hydrazine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-piperidin-1-ylethyl)pyrimidine-2,4-diamine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-pyrrolidin-1-ylethyl)pyrimidine-2,4-diamine;5-[[5-(cyclopenten-1-yl)-2-methoxy-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(5-cyclopentyl-2-methoxy-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[[2-[(dimethylamino)methyl]-5-propan-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[[2-(ethylamino)-5-prop-1-en-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-N,2-dimethylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methyl-N-propan-2-ylpyrimidin-4-amine;2-[[5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]amino]ethanol;5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[(2-methoxy-5-morpholin-4-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;2-methyl-5-[(2-methylsulfanyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-amine
SMILESC#Cc1cc(Oc2cnc(C)nc2N)c(C(=C)C)cn1.C#Cc1cc(Oc2cnc(C)nc2NC(C)C)c(C(C)C)cn1.C#Cc1cc(Oc2cnc(C)nc2NC)c(C(C)C)cn1.C#Cc1cc(Oc2cnc(C)nc2NCCO)c(C(C)C)cn1.C#Cc1cc(Oc2cnc(N)nc2NCC(O)CC)c(C(=C)C)cn1.C=C(C)c1cnc(NCC)cc1Oc1cnc(C)nc1N.C=C(C)c1cnc(SC)cc1Oc1cnc(C)nc1N.CC(C)c1cnc(Br)cc1Oc1cnc(N)nc1NCCN1CCCC1.CC(C)c1cnc(Br)cc1Oc1cnc(N)nc1NCCN1CCCCC1.CCC(CO)Nc1ncc(Oc2cc(Cl)ncc2C(C)C)c(N)n1.CCC(O)CNc1nc(N)ncc1Oc1cc(Br)ncc1C(C)C.CC[C@@H](CO)Nc1nc(N)ncc1Oc1cc(Br)ncc1C(C)C.COCCNc1nc(N)ncc1Oc1cc(Br)ncc1C(C)C.COc1cc(Oc2cnc(C)nc2N)c(C2=CCCC2)cn1.COc1cc(Oc2cnc(C)nc2N)c(C2CCCC2)cn1.COc1cc(Oc2cnc(C)nc2N)c(N2CCOCC2)cn1.Cc1ncc(Oc2cc(Br)ncc2C(C)C)c(NN)n1.Cc1ncc(Oc2cc(CN(C)C)ncc2C(C)C)c(N)n1
InChIInChI=1S/C19H27BrN6O.C18H25BrN6O.C18H21N5O2.C18H22N4O.C17H20N4O2.2C16H22BrN5O2.C16H22ClN5O2.C16H23N5O.C16H20N4O2.C16H18N4O2.C16H18N4O.C15H20BrN5O2.C15H19N5O3.C15H19N5O.C15H14N4O.C14H16N4OS.C13H16BrN5O/c1-13(2)14-11-23-17(20)10-15(14)27-16-12-24-19(21)25-18(16)22-6-9-26-7-4-3-5-8-26;1-12(2)13-10-22-16(19)9-14(13)26-15-11-23-18(20)24-17(15)21-5-8-25-6-3-4-7-25;1-5-12-7-15(14(9-20-12)11(3)4)25-16-10-22-18(19)23-17(16)21-8-13(24)6-2;1-7-14-8-16(15(9-20-14)11(2)3)23-17-10-19-13(6)22-18(17)21-12(4)5;1-5-13-8-15(14(9-20-13)11(2)3)23-16-10-19-12(4)21-17(16)18-6-7-22;1-4-10(8-23)21-15-13(7-20-16(18)22-15)24-12-5-14(17)19-6-11(12)9(2)3;1-4-10(23)6-20-15-13(8-21-16(18)22-15)24-12-5-14(17)19-7-11(12)9(2)3;1-4-10(8-23)21-16-20-7-13(15(18)22-16)24-12-5-14(17)19-6-11(12)9(2)3;1-10(2)13-7-19-12(9-21(4)5)6-14(13)22-15-8-18-11(3)20-16(15)17;2*1-10-18-9-14(16(17)20-10)22-13-7-15(21-2)19-8-12(13)11-5-3-4-6-11;1-6-12-7-14(13(8-19-12)10(2)3)21-15-9-18-11(4)20-16(15)17-5;1-9(2)10-7-19-13(16)6-11(10)23-12-8-20-15(17)21-14(12)18-4-5-22-3;1-10-17-9-13(15(16)19-10)23-12-7-14(21-2)18-8-11(12)20-3-5-22-6-4-20;1-5-17-14-6-12(11(7-19-14)9(2)3)21-13-8-18-10(4)20-15(13)16;1-5-11-6-13(12(7-18-11)9(2)3)20-14-8-17-10(4)19-15(14)16;1-8(2)10-6-17-13(20-4)5-11(10)19-12-7-16-9(3)18-14(12)15;1-7(2)9-5-17-12(14)4-10(9)20-11-6-16-8(3)18-13(11)19-15/h10-13H,3-9H2,1-2H3,(H3,21,22,24,25);9-12H,3-8H2,1-2H3,(H3,20,21,23,24);1,7,9-10,13,24H,3,6,8H2,2,4H3,(H3,19,21,22,23);1,8-12H,2-6H3,(H,19,21,22);1,8-11,22H,6-7H2,2-4H3,(H,18,19,21);5-7,9-10,23H,4,8H2,1-3H3,(H3,18,20,21,22);5,7-10,23H,4,6H2,1-3H3,(H3,18,20,21,22);5-7,9-10,23H,4,8H2,1-3H3,(H3,18,20,21,22);6-8,10H,9H2,1-5H3,(H2,17,18,20);7-9,11H,3-6H2,1-2H3,(H2,17,18,20);5,7-9H,3-4,6H2,1-2H3,(H2,17,18,20);1,7-10H,2-5H3,(H,17,18,20);6-9H,4-5H2,1-3H3,(H3,17,18,20,21);7-9H,3-6H2,1-2H3,(H2,16,17,19);6-8H,2,5H2,1,3-4H3,(H,17,19)(H2,16,18,20);1,6-8H,2H2,3-4H3,(H2,16,17,19);5-7H,1H2,2-4H3,(H2,15,16,18);4-7H,15H2,1-3H3,(H,16,18,19)/t;;;;;10-;;;;;;;;;;;;/m.....0............/s1
InChIKeyJZPRQBJOGSNMEY-SGHTYZDJSA-N
MW6023.60 g/mol
LogP55.17
Rot. Bonds97

About 1-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;(2S)-2-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-1-ol;2-[[4-amino-5-[(2-chloro-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-2-yl]amino]butan-1-ol;1-[[2-amino-5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-methoxyethyl)pyrimidine-2,4-diamine;[5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]hydrazine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-piperidin-1-ylethyl)pyrimidine-2,4-diamine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-pyrrolidin-1-ylethyl)pyrimidine-2,4-diamine;5-[[5-(cyclopenten-1-yl)-2-methoxy-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(5-cyclopentyl-2-methoxy-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[[2-[(dimethylamino)methyl]-5-propan-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[[2-(ethylamino)-5-prop-1-en-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-N,2-dimethylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methyl-N-propan-2-ylpyrimidin-4-amine;2-[[5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]amino]ethanol;5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[(2-methoxy-5-morpholin-4-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;2-methyl-5-[(2-methylsulfanyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-amine

1-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;(2S)-2-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-1-ol;2-[[4-amino-5-[(2-chloro-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-2-yl]amino]butan-1-ol;1-[[2-amino-5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-methoxyethyl)pyrimidine-2,4-diamine;[5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]hydrazine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-piperidin-1-ylethyl)pyrimidine-2,4-diamine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-pyrrolidin-1-ylethyl)pyrimidine-2,4-diamine;5-[[5-(cyclopenten-1-yl)-2-methoxy-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(5-cyclopentyl-2-methoxy-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[[2-[(dimethylamino)methyl]-5-propan-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[[2-(ethylamino)-5-prop-1-en-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-N,2-dimethylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methyl-N-propan-2-ylpyrimidin-4-amine;2-[[5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]amino]ethanol;5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[(2-methoxy-5-morpholin-4-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;2-methyl-5-[(2-methylsulfanyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-amine (PubChem CID 159070759) has the molecular formula C289H364Br6ClN85O28S and a molecular weight of 6023.60 g/mol. Its IUPAC name is 1-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;(2S)-2-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-1-ol;2-[[4-amino-5-[(2-chloro-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-2-yl]amino]butan-1-ol;1-[[2-amino-5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-methoxyethyl)pyrimidine-2,4-diamine;[5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]hydrazine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-piperidin-1-ylethyl)pyrimidine-2,4-diamine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-pyrrolidin-1-ylethyl)pyrimidine-2,4-diamine;5-[[5-(cyclopenten-1-yl)-2-methoxy-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(5-cyclopentyl-2-methoxy-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[[2-[(dimethylamino)methyl]-5-propan-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[[2-(ethylamino)-5-prop-1-en-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-N,2-dimethylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methyl-N-propan-2-ylpyrimidin-4-amine;2-[[5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]amino]ethanol;5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[(2-methoxy-5-morpholin-4-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;2-methyl-5-[(2-methylsulfanyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-amine.

Molecular Properties

Compound Name1-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;(2S)-2-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-1-ol;2-[[4-amino-5-[(2-chloro-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-2-yl]amino]butan-1-ol;1-[[2-amino-5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-methoxyethyl)pyrimidine-2,4-diamine;[5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]hydrazine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-piperidin-1-ylethyl)pyrimidine-2,4-diamine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-pyrrolidin-1-ylethyl)pyrimidine-2,4-diamine;5-[[5-(cyclopenten-1-yl)-2-methoxy-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(5-cyclopentyl-2-methoxy-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[[2-[(dimethylamino)methyl]-5-propan-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[[2-(ethylamino)-5-prop-1-en-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-N,2-dimethylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methyl-N-propan-2-ylpyrimidin-4-amine;2-[[5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]amino]ethanol;5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[(2-methoxy-5-morpholin-4-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;2-methyl-5-[(2-methylsulfanyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-amine
PubChem CID159070759
Molecular FormulaC289H364Br6ClN85O28S
Molecular Weight6023.60 g/mol
Exact Mass6013.42
IUPAC Name1-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;(2S)-2-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-1-ol;2-[[4-amino-5-[(2-chloro-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-2-yl]amino]butan-1-ol;1-[[2-amino-5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-methoxyethyl)pyrimidine-2,4-diamine;[5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]hydrazine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-piperidin-1-ylethyl)pyrimidine-2,4-diamine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-pyrrolidin-1-ylethyl)pyrimidine-2,4-diamine;5-[[5-(cyclopenten-1-yl)-2-methoxy-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(5-cyclopentyl-2-methoxy-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[[2-[(dimethylamino)methyl]-5-propan-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[[2-(ethylamino)-5-prop-1-en-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-N,2-dimethylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methyl-N-propan-2-ylpyrimidin-4-amine;2-[[5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]amino]ethanol;5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[(2-methoxy-5-morpholin-4-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;2-methyl-5-[(2-methylsulfanyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-amine
SMILESC#Cc1cc(Oc2cnc(C)nc2N)c(C(=C)C)cn1.C#Cc1cc(Oc2cnc(C)nc2NC(C)C)c(C(C)C)cn1.C#Cc1cc(Oc2cnc(C)nc2NC)c(C(C)C)cn1.C#Cc1cc(Oc2cnc(C)nc2NCCO)c(C(C)C)cn1.C#Cc1cc(Oc2cnc(N)nc2NCC(O)CC)c(C(=C)C)cn1.C=C(C)c1cnc(NCC)cc1Oc1cnc(C)nc1N.C=C(C)c1cnc(SC)cc1Oc1cnc(C)nc1N.CC(C)c1cnc(Br)cc1Oc1cnc(N)nc1NCCN1CCCC1.CC(C)c1cnc(Br)cc1Oc1cnc(N)nc1NCCN1CCCCC1.CCC(CO)Nc1ncc(Oc2cc(Cl)ncc2C(C)C)c(N)n1.CCC(O)CNc1nc(N)ncc1Oc1cc(Br)ncc1C(C)C.CC[C@@H](CO)Nc1nc(N)ncc1Oc1cc(Br)ncc1C(C)C.COCCNc1nc(N)ncc1Oc1cc(Br)ncc1C(C)C.COc1cc(Oc2cnc(C)nc2N)c(C2=CCCC2)cn1.COc1cc(Oc2cnc(C)nc2N)c(C2CCCC2)cn1.COc1cc(Oc2cnc(C)nc2N)c(N2CCOCC2)cn1.Cc1ncc(Oc2cc(Br)ncc2C(C)C)c(NN)n1.Cc1ncc(Oc2cc(CN(C)C)ncc2C(C)C)c(N)n1
InChIInChI=1S/C19H27BrN6O.C18H25BrN6O.C18H21N5O2.C18H22N4O.C17H20N4O2.2C16H22BrN5O2.C16H22ClN5O2.C16H23N5O.C16H20N4O2.C16H18N4O2.C16H18N4O.C15H20BrN5O2.C15H19N5O3.C15H19N5O.C15H14N4O.C14H16N4OS.C13H16BrN5O/c1-13(2)14-11-23-17(20)10-15(14)27-16-12-24-19(21)25-18(16)22-6-9-26-7-4-3-5-8-26;1-12(2)13-10-22-16(19)9-14(13)26-15-11-23-18(20)24-17(15)21-5-8-25-6-3-4-7-25;1-5-12-7-15(14(9-20-12)11(3)4)25-16-10-22-18(19)23-17(16)21-8-13(24)6-2;1-7-14-8-16(15(9-20-14)11(2)3)23-17-10-19-13(6)22-18(17)21-12(4)5;1-5-13-8-15(14(9-20-13)11(2)3)23-16-10-19-12(4)21-17(16)18-6-7-22;1-4-10(8-23)21-15-13(7-20-16(18)22-15)24-12-5-14(17)19-6-11(12)9(2)3;1-4-10(23)6-20-15-13(8-21-16(18)22-15)24-12-5-14(17)19-7-11(12)9(2)3;1-4-10(8-23)21-16-20-7-13(15(18)22-16)24-12-5-14(17)19-6-11(12)9(2)3;1-10(2)13-7-19-12(9-21(4)5)6-14(13)22-15-8-18-11(3)20-16(15)17;2*1-10-18-9-14(16(17)20-10)22-13-7-15(21-2)19-8-12(13)11-5-3-4-6-11;1-6-12-7-14(13(8-19-12)10(2)3)21-15-9-18-11(4)20-16(15)17-5;1-9(2)10-7-19-13(16)6-11(10)23-12-8-20-15(17)21-14(12)18-4-5-22-3;1-10-17-9-13(15(16)19-10)23-12-7-14(21-2)18-8-11(12)20-3-5-22-6-4-20;1-5-17-14-6-12(11(7-19-14)9(2)3)21-13-8-18-10(4)20-15(13)16;1-5-11-6-13(12(7-18-11)9(2)3)20-14-8-17-10(4)19-15(14)16;1-8(2)10-6-17-13(20-4)5-11(10)19-12-7-16-9(3)18-14(12)15;1-7(2)9-5-17-12(14)4-10(9)20-11-6-16-8(3)18-13(11)19-15/h10-13H,3-9H2,1-2H3,(H3,21,22,24,25);9-12H,3-8H2,1-2H3,(H3,20,21,23,24);1,7,9-10,13,24H,3,6,8H2,2,4H3,(H3,19,21,22,23);1,8-12H,2-6H3,(H,19,21,22);1,8-11,22H,6-7H2,2-4H3,(H,18,19,21);5-7,9-10,23H,4,8H2,1-3H3,(H3,18,20,21,22);5,7-10,23H,4,6H2,1-3H3,(H3,18,20,21,22);5-7,9-10,23H,4,8H2,1-3H3,(H3,18,20,21,22);6-8,10H,9H2,1-5H3,(H2,17,18,20);7-9,11H,3-6H2,1-2H3,(H2,17,18,20);5,7-9H,3-4,6H2,1-2H3,(H2,17,18,20);1,7-10H,2-5H3,(H,17,18,20);6-9H,4-5H2,1-3H3,(H3,17,18,20,21);7-9H,3-6H2,1-2H3,(H2,16,17,19);6-8H,2,5H2,1,3-4H3,(H,17,19)(H2,16,18,20);1,6-8H,2H2,3-4H3,(H2,16,17,19);5-7H,1H2,2-4H3,(H2,15,16,18);4-7H,15H2,1-3H3,(H,16,18,19)/t;;;;;10-;;;;;;;;;;;;/m.....0............/s1
InChIKeyJZPRQBJOGSNMEY-SGHTYZDJSA-N
XLogP55.17
TPSA1557.12 Ų
H-Bond Donors32
H-Bond Acceptors114
Rotatable Bonds97
Heavy Atoms410
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5006023.60
LogP ≤ 555.17
H-Bond Donors ≤ 532
H-Bond Acceptors ≤ 10114

Analyze 1-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;(2S)-2-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-1-ol;2-[[4-amino-5-[(2-chloro-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-2-yl]amino]butan-1-ol;1-[[2-amino-5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-methoxyethyl)pyrimidine-2,4-diamine;[5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]hydrazine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-piperidin-1-ylethyl)pyrimidine-2,4-diamine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-pyrrolidin-1-ylethyl)pyrimidine-2,4-diamine;5-[[5-(cyclopenten-1-yl)-2-methoxy-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(5-cyclopentyl-2-methoxy-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[[2-[(dimethylamino)methyl]-5-propan-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[[2-(ethylamino)-5-prop-1-en-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-N,2-dimethylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methyl-N-propan-2-ylpyrimidin-4-amine;2-[[5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]amino]ethanol;5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[(2-methoxy-5-morpholin-4-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;2-methyl-5-[(2-methylsulfanyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-amine with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Frequently Asked Questions

What is the IUPAC name of 1-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;(2S)-2-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-1-ol;2-[[4-amino-5-[(2-chloro-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-2-yl]amino]butan-1-ol;1-[[2-amino-5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-methoxyethyl)pyrimidine-2,4-diamine;[5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]hydrazine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-piperidin-1-ylethyl)pyrimidine-2,4-diamine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-pyrrolidin-1-ylethyl)pyrimidine-2,4-diamine;5-[[5-(cyclopenten-1-yl)-2-methoxy-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(5-cyclopentyl-2-methoxy-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[[2-[(dimethylamino)methyl]-5-propan-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[[2-(ethylamino)-5-prop-1-en-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-N,2-dimethylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methyl-N-propan-2-ylpyrimidin-4-amine;2-[[5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]amino]ethanol;5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[(2-methoxy-5-morpholin-4-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;2-methyl-5-[(2-methylsulfanyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-amine?
The IUPAC name of 1-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;(2S)-2-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-1-ol;2-[[4-amino-5-[(2-chloro-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-2-yl]amino]butan-1-ol;1-[[2-amino-5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-methoxyethyl)pyrimidine-2,4-diamine;[5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]hydrazine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-piperidin-1-ylethyl)pyrimidine-2,4-diamine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-pyrrolidin-1-ylethyl)pyrimidine-2,4-diamine;5-[[5-(cyclopenten-1-yl)-2-methoxy-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(5-cyclopentyl-2-methoxy-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[[2-[(dimethylamino)methyl]-5-propan-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[[2-(ethylamino)-5-prop-1-en-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-N,2-dimethylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methyl-N-propan-2-ylpyrimidin-4-amine;2-[[5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]amino]ethanol;5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[(2-methoxy-5-morpholin-4-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;2-methyl-5-[(2-methylsulfanyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-amine (CID 159070759) is 1-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;(2S)-2-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-1-ol;2-[[4-amino-5-[(2-chloro-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-2-yl]amino]butan-1-ol;1-[[2-amino-5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-methoxyethyl)pyrimidine-2,4-diamine;[5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]hydrazine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-piperidin-1-ylethyl)pyrimidine-2,4-diamine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-pyrrolidin-1-ylethyl)pyrimidine-2,4-diamine;5-[[5-(cyclopenten-1-yl)-2-methoxy-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(5-cyclopentyl-2-methoxy-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[[2-[(dimethylamino)methyl]-5-propan-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[[2-(ethylamino)-5-prop-1-en-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-N,2-dimethylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methyl-N-propan-2-ylpyrimidin-4-amine;2-[[5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]amino]ethanol;5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[(2-methoxy-5-morpholin-4-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;2-methyl-5-[(2-methylsulfanyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-amine.
What is the SMILES notation for 1-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;(2S)-2-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-1-ol;2-[[4-amino-5-[(2-chloro-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-2-yl]amino]butan-1-ol;1-[[2-amino-5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-methoxyethyl)pyrimidine-2,4-diamine;[5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]hydrazine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-piperidin-1-ylethyl)pyrimidine-2,4-diamine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-pyrrolidin-1-ylethyl)pyrimidine-2,4-diamine;5-[[5-(cyclopenten-1-yl)-2-methoxy-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(5-cyclopentyl-2-methoxy-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[[2-[(dimethylamino)methyl]-5-propan-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[[2-(ethylamino)-5-prop-1-en-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-N,2-dimethylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methyl-N-propan-2-ylpyrimidin-4-amine;2-[[5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]amino]ethanol;5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[(2-methoxy-5-morpholin-4-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;2-methyl-5-[(2-methylsulfanyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-amine?
The canonical SMILES for 1-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;(2S)-2-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-1-ol;2-[[4-amino-5-[(2-chloro-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-2-yl]amino]butan-1-ol;1-[[2-amino-5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-methoxyethyl)pyrimidine-2,4-diamine;[5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]hydrazine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-piperidin-1-ylethyl)pyrimidine-2,4-diamine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-pyrrolidin-1-ylethyl)pyrimidine-2,4-diamine;5-[[5-(cyclopenten-1-yl)-2-methoxy-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(5-cyclopentyl-2-methoxy-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[[2-[(dimethylamino)methyl]-5-propan-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[[2-(ethylamino)-5-prop-1-en-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-N,2-dimethylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methyl-N-propan-2-ylpyrimidin-4-amine;2-[[5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]amino]ethanol;5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[(2-methoxy-5-morpholin-4-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;2-methyl-5-[(2-methylsulfanyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-amine is C#Cc1cc(Oc2cnc(C)nc2N)c(C(=C)C)cn1.C#Cc1cc(Oc2cnc(C)nc2NC(C)C)c(C(C)C)cn1.C#Cc1cc(Oc2cnc(C)nc2NC)c(C(C)C)cn1.C#Cc1cc(Oc2cnc(C)nc2NCCO)c(C(C)C)cn1.C#Cc1cc(Oc2cnc(N)nc2NCC(O)CC)c(C(=C)C)cn1.C=C(C)c1cnc(NCC)cc1Oc1cnc(C)nc1N.C=C(C)c1cnc(SC)cc1Oc1cnc(C)nc1N.CC(C)c1cnc(Br)cc1Oc1cnc(N)nc1NCCN1CCCC1.CC(C)c1cnc(Br)cc1Oc1cnc(N)nc1NCCN1CCCCC1.CCC(CO)Nc1ncc(Oc2cc(Cl)ncc2C(C)C)c(N)n1.CCC(O)CNc1nc(N)ncc1Oc1cc(Br)ncc1C(C)C.CC[C@@H](CO)Nc1nc(N)ncc1Oc1cc(Br)ncc1C(C)C.COCCNc1nc(N)ncc1Oc1cc(Br)ncc1C(C)C.COc1cc(Oc2cnc(C)nc2N)c(C2=CCCC2)cn1.COc1cc(Oc2cnc(C)nc2N)c(C2CCCC2)cn1.COc1cc(Oc2cnc(C)nc2N)c(N2CCOCC2)cn1.Cc1ncc(Oc2cc(Br)ncc2C(C)C)c(NN)n1.Cc1ncc(Oc2cc(CN(C)C)ncc2C(C)C)c(N)n1.
What is the InChIKey of 1-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;(2S)-2-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-1-ol;2-[[4-amino-5-[(2-chloro-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-2-yl]amino]butan-1-ol;1-[[2-amino-5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-methoxyethyl)pyrimidine-2,4-diamine;[5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]hydrazine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-piperidin-1-ylethyl)pyrimidine-2,4-diamine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-pyrrolidin-1-ylethyl)pyrimidine-2,4-diamine;5-[[5-(cyclopenten-1-yl)-2-methoxy-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(5-cyclopentyl-2-methoxy-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[[2-[(dimethylamino)methyl]-5-propan-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[[2-(ethylamino)-5-prop-1-en-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-N,2-dimethylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methyl-N-propan-2-ylpyrimidin-4-amine;2-[[5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]amino]ethanol;5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[(2-methoxy-5-morpholin-4-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;2-methyl-5-[(2-methylsulfanyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-amine?
The InChIKey is JZPRQBJOGSNMEY-SGHTYZDJSA-N. The full InChI is InChI=1S/C19H27BrN6O.C18H25BrN6O.C18H21N5O2.C18H22N4O.C17H20N4O2.2C16H22BrN5O2.C16H22ClN5O2.C16H23N5O.C16H20N4O2.C16H18N4O2.C16H18N4O.C15H20BrN5O2.C15H19N5O3.C15H19N5O.C15H14N4O.C14H16N4OS.C13H16BrN5O/c1-13(2)14-11-23-17(20)10-15(14)27-16-12-24-19(21)25-18(16)22-6-9-26-7-4-3-5-8-26;1-12(2)13-10-22-16(19)9-14(13)26-15-11-23-18(20)24-17(15)21-5-8-25-6-3-4-7-25;1-5-12-7-15(14(9-20-12)11(3)4)25-16-10-22-18(19)23-17(16)21-8-13(24)6-2;1-7-14-8-16(15(9-20-14)11(2)3)23-17-10-19-13(6)22-18(17)21-12(4)5;1-5-13-8-15(14(9-20-13)11(2)3)23-16-10-19-12(4)21-17(16)18-6-7-22;1-4-10(8-23)21-15-13(7-20-16(18)22-15)24-12-5-14(17)19-6-11(12)9(2)3;1-4-10(23)6-20-15-13(8-21-16(18)22-15)24-12-5-14(17)19-7-11(12)9(2)3;1-4-10(8-23)21-16-20-7-13(15(18)22-16)24-12-5-14(17)19-6-11(12)9(2)3;1-10(2)13-7-19-12(9-21(4)5)6-14(13)22-15-8-18-11(3)20-16(15)17;2*1-10-18-9-14(16(17)20-10)22-13-7-15(21-2)19-8-12(13)11-5-3-4-6-11;1-6-12-7-14(13(8-19-12)10(2)3)21-15-9-18-11(4)20-16(15)17-5;1-9(2)10-7-19-13(16)6-11(10)23-12-8-20-15(17)21-14(12)18-4-5-22-3;1-10-17-9-13(15(16)19-10)23-12-7-14(21-2)18-8-11(12)20-3-5-22-6-4-20;1-5-17-14-6-12(11(7-19-14)9(2)3)21-13-8-18-10(4)20-15(13)16;1-5-11-6-13(12(7-18-11)9(2)3)20-14-8-17-10(4)19-15(14)16;1-8(2)10-6-17-13(20-4)5-11(10)19-12-7-16-9(3)18-14(12)15;1-7(2)9-5-17-12(14)4-10(9)20-11-6-16-8(3)18-13(11)19-15/h10-13H,3-9H2,1-2H3,(H3,21,22,24,25);9-12H,3-8H2,1-2H3,(H3,20,21,23,24);1,7,9-10,13,24H,3,6,8H2,2,4H3,(H3,19,21,22,23);1,8-12H,2-6H3,(H,19,21,22);1,8-11,22H,6-7H2,2-4H3,(H,18,19,21);5-7,9-10,23H,4,8H2,1-3H3,(H3,18,20,21,22);5,7-10,23H,4,6H2,1-3H3,(H3,18,20,21,22);5-7,9-10,23H,4,8H2,1-3H3,(H3,18,20,21,22);6-8,10H,9H2,1-5H3,(H2,17,18,20);7-9,11H,3-6H2,1-2H3,(H2,17,18,20);5,7-9H,3-4,6H2,1-2H3,(H2,17,18,20);1,7-10H,2-5H3,(H,17,18,20);6-9H,4-5H2,1-3H3,(H3,17,18,20,21);7-9H,3-6H2,1-2H3,(H2,16,17,19);6-8H,2,5H2,1,3-4H3,(H,17,19)(H2,16,18,20);1,6-8H,2H2,3-4H3,(H2,16,17,19);5-7H,1H2,2-4H3,(H2,15,16,18);4-7H,15H2,1-3H3,(H,16,18,19)/t;;;;;10-;;;;;;;;;;;;/m.....0............/s1.
What are the key properties of 1-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;(2S)-2-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-1-ol;2-[[4-amino-5-[(2-chloro-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-2-yl]amino]butan-1-ol;1-[[2-amino-5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-methoxyethyl)pyrimidine-2,4-diamine;[5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]hydrazine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-piperidin-1-ylethyl)pyrimidine-2,4-diamine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-pyrrolidin-1-ylethyl)pyrimidine-2,4-diamine;5-[[5-(cyclopenten-1-yl)-2-methoxy-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(5-cyclopentyl-2-methoxy-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[[2-[(dimethylamino)methyl]-5-propan-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[[2-(ethylamino)-5-prop-1-en-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-N,2-dimethylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methyl-N-propan-2-ylpyrimidin-4-amine;2-[[5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]amino]ethanol;5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[(2-methoxy-5-morpholin-4-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;2-methyl-5-[(2-methylsulfanyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-amine?
1-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;(2S)-2-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-1-ol;2-[[4-amino-5-[(2-chloro-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-2-yl]amino]butan-1-ol;1-[[2-amino-5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-methoxyethyl)pyrimidine-2,4-diamine;[5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]hydrazine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-piperidin-1-ylethyl)pyrimidine-2,4-diamine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-pyrrolidin-1-ylethyl)pyrimidine-2,4-diamine;5-[[5-(cyclopenten-1-yl)-2-methoxy-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(5-cyclopentyl-2-methoxy-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[[2-[(dimethylamino)methyl]-5-propan-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[[2-(ethylamino)-5-prop-1-en-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-N,2-dimethylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methyl-N-propan-2-ylpyrimidin-4-amine;2-[[5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]amino]ethanol;5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[(2-methoxy-5-morpholin-4-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;2-methyl-5-[(2-methylsulfanyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-amine has a molecular weight of 6023.60 g/mol, XLogP of 55.17, 97 rotatable bonds, 32 hydrogen bond donors, and 114 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;(2S)-2-[[2-amino-5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-1-ol;2-[[4-amino-5-[(2-chloro-5-propan-2-yl-4-pyridinyl)oxy]pyrimidin-2-yl]amino]butan-1-ol;1-[[2-amino-5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-yl]amino]butan-2-ol;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-methoxyethyl)pyrimidine-2,4-diamine;[5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]hydrazine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-piperidin-1-ylethyl)pyrimidine-2,4-diamine;5-[(2-bromo-5-propan-2-yl-4-pyridinyl)oxy]-4-N-(2-pyrrolidin-1-ylethyl)pyrimidine-2,4-diamine;5-[[5-(cyclopenten-1-yl)-2-methoxy-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(5-cyclopentyl-2-methoxy-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[[2-[(dimethylamino)methyl]-5-propan-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[[2-(ethylamino)-5-prop-1-en-2-yl-4-pyridinyl]oxy]-2-methylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-N,2-dimethylpyrimidin-4-amine;5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methyl-N-propan-2-ylpyrimidin-4-amine;2-[[5-[(2-ethynyl-5-propan-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-yl]amino]ethanol;5-[(2-ethynyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;5-[(2-methoxy-5-morpholin-4-yl-4-pyridinyl)oxy]-2-methylpyrimidin-4-amine;2-methyl-5-[(2-methylsulfanyl-5-prop-1-en-2-yl-4-pyridinyl)oxy]pyrimidin-4-amine is sourced from PubChem (CID 159070759), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).