N-[5-(cyclopropylsulfamoyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-5-(6-methyl-2-pyridinyl)-2,3-dihydro-1H-indene-2-carboxamide;5-[6-(dimethylamino)-2-pyridinyl]-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;5-(3-fluoro-2-pyridinyl)-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;bis(N-methyl-5-(6-methyl-2-pyridinyl)-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide)

C108H114FN21O15S10 — CID 159072208

IUPACN-[5-(cyclopropylsulfamoyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-5-(6-methyl-2-pyridinyl)-2,3-dihydro-1H-indene-2-carboxamide;5-[6-(dimethylamino)-2-pyridinyl]-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;5-(3-fluoro-2-pyridinyl)-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;bis(N-methyl-5-(6-methyl-2-pyridinyl)-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide)
SMILESCc1cccc(-c2ccc3c(c2)CC(C(=O)N(C)c2nc(C)c(S(=O)(=O)NC4CC4)s2)C3)n1.Cc1cccc(-c2ccc3c(c2)CC(C(=O)N(C)c2nc(C)c(S(N)(=O)=O)s2)C3)n1.Cc1cccc(-c2ccc3c(c2)CC(C(=O)N(C)c2nc(C)c(S(N)(=O)=O)s2)C3)n1.Cc1nc(N(C)C(=O)C2Cc3ccc(-c4cccc(N(C)C)n4)cc3C2)sc1S(N)(=O)=O.Cc1nc(N(C)C(=O)C2Cc3ccc(-c4ncccc4F)cc3C2)sc1S(N)(=O)=O
InChIInChI=1S/C24H26N4O3S2.C22H25N5O3S2.2C21H22N4O3S2.C20H19FN4O3S2/c1-14-5-4-6-21(25-14)17-8-7-16-11-19(13-18(16)12-17)22(29)28(3)24-26-15(2)23(32-24)33(30,31)27-20-9-10-20;1-13-21(32(23,29)30)31-22(24-13)27(4)20(28)17-10-14-8-9-15(11-16(14)12-17)18-6-5-7-19(25-18)26(2)3;2*1-12-5-4-6-18(23-12)15-8-7-14-9-17(11-16(14)10-15)19(26)25(3)21-24-13(2)20(29-21)30(22,27)28;1-11-19(30(22,27)28)29-20(24-11)25(2)18(26)15-8-12-5-6-13(9-14(12)10-15)17-16(21)4-3-7-23-17/h4-8,12,19-20,27H,9-11,13H2,1-3H3;5-9,11,17H,10,12H2,1-4H3,(H2,23,29,30);2*4-8,10,17H,9,11H2,1-3H3,(H2,22,27,28);3-7,9,15H,8,10H2,1-2H3,(H2,22,27,28)
InChIKeyJZULDSBIWLRFKS-UHFFFAOYSA-N
MW2285.90 g/mol
LogP14.62
Rot. Bonds23

About N-[5-(cyclopropylsulfamoyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-5-(6-methyl-2-pyridinyl)-2,3-dihydro-1H-indene-2-carboxamide;5-[6-(dimethylamino)-2-pyridinyl]-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;5-(3-fluoro-2-pyridinyl)-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;bis(N-methyl-5-(6-methyl-2-pyridinyl)-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide)

N-[5-(cyclopropylsulfamoyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-5-(6-methyl-2-pyridinyl)-2,3-dihydro-1H-indene-2-carboxamide;5-[6-(dimethylamino)-2-pyridinyl]-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;5-(3-fluoro-2-pyridinyl)-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;bis(N-methyl-5-(6-methyl-2-pyridinyl)-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide) (PubChem CID 159072208) has the molecular formula C108H114FN21O15S10 and a molecular weight of 2285.90 g/mol. Its IUPAC name is N-[5-(cyclopropylsulfamoyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-5-(6-methyl-2-pyridinyl)-2,3-dihydro-1H-indene-2-carboxamide;5-[6-(dimethylamino)-2-pyridinyl]-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;5-(3-fluoro-2-pyridinyl)-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;bis(N-methyl-5-(6-methyl-2-pyridinyl)-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide).

Molecular Properties

Compound NameN-[5-(cyclopropylsulfamoyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-5-(6-methyl-2-pyridinyl)-2,3-dihydro-1H-indene-2-carboxamide;5-[6-(dimethylamino)-2-pyridinyl]-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;5-(3-fluoro-2-pyridinyl)-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;bis(N-methyl-5-(6-methyl-2-pyridinyl)-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide)
PubChem CID159072208
Molecular FormulaC108H114FN21O15S10
Molecular Weight2285.90 g/mol
Exact Mass2283.60
IUPAC NameN-[5-(cyclopropylsulfamoyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-5-(6-methyl-2-pyridinyl)-2,3-dihydro-1H-indene-2-carboxamide;5-[6-(dimethylamino)-2-pyridinyl]-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;5-(3-fluoro-2-pyridinyl)-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;bis(N-methyl-5-(6-methyl-2-pyridinyl)-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide)
SMILESCc1cccc(-c2ccc3c(c2)CC(C(=O)N(C)c2nc(C)c(S(=O)(=O)NC4CC4)s2)C3)n1.Cc1cccc(-c2ccc3c(c2)CC(C(=O)N(C)c2nc(C)c(S(N)(=O)=O)s2)C3)n1.Cc1cccc(-c2ccc3c(c2)CC(C(=O)N(C)c2nc(C)c(S(N)(=O)=O)s2)C3)n1.Cc1nc(N(C)C(=O)C2Cc3ccc(-c4cccc(N(C)C)n4)cc3C2)sc1S(N)(=O)=O.Cc1nc(N(C)C(=O)C2Cc3ccc(-c4ncccc4F)cc3C2)sc1S(N)(=O)=O
InChIInChI=1S/C24H26N4O3S2.C22H25N5O3S2.2C21H22N4O3S2.C20H19FN4O3S2/c1-14-5-4-6-21(25-14)17-8-7-16-11-19(13-18(16)12-17)22(29)28(3)24-26-15(2)23(32-24)33(30,31)27-20-9-10-20;1-13-21(32(23,29)30)31-22(24-13)27(4)20(28)17-10-14-8-9-15(11-16(14)12-17)18-6-5-7-19(25-18)26(2)3;2*1-12-5-4-6-18(23-12)15-8-7-14-9-17(11-16(14)10-15)19(26)25(3)21-24-13(2)20(29-21)30(22,27)28;1-11-19(30(22,27)28)29-20(24-11)25(2)18(26)15-8-12-5-6-13(9-14(12)10-15)17-16(21)4-3-7-23-17/h4-8,12,19-20,27H,9-11,13H2,1-3H3;5-9,11,17H,10,12H2,1-4H3,(H2,23,29,30);2*4-8,10,17H,9,11H2,1-3H3,(H2,22,27,28);3-7,9,15H,8,10H2,1-2H3,(H2,22,27,28)
InChIKeyJZULDSBIWLRFKS-UHFFFAOYSA-N
XLogP14.62
TPSA520.50 Ų
H-Bond Donors5
H-Bond Acceptors31
Rotatable Bonds23
Heavy Atoms155
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002285.90
LogP ≤ 514.62
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1031

Analyze N-[5-(cyclopropylsulfamoyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-5-(6-methyl-2-pyridinyl)-2,3-dihydro-1H-indene-2-carboxamide;5-[6-(dimethylamino)-2-pyridinyl]-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;5-(3-fluoro-2-pyridinyl)-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;bis(N-methyl-5-(6-methyl-2-pyridinyl)-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide) with MolForge

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Frequently Asked Questions

What is the IUPAC name of N-[5-(cyclopropylsulfamoyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-5-(6-methyl-2-pyridinyl)-2,3-dihydro-1H-indene-2-carboxamide;5-[6-(dimethylamino)-2-pyridinyl]-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;5-(3-fluoro-2-pyridinyl)-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;bis(N-methyl-5-(6-methyl-2-pyridinyl)-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide)?
The IUPAC name of N-[5-(cyclopropylsulfamoyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-5-(6-methyl-2-pyridinyl)-2,3-dihydro-1H-indene-2-carboxamide;5-[6-(dimethylamino)-2-pyridinyl]-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;5-(3-fluoro-2-pyridinyl)-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;bis(N-methyl-5-(6-methyl-2-pyridinyl)-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide) (CID 159072208) is N-[5-(cyclopropylsulfamoyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-5-(6-methyl-2-pyridinyl)-2,3-dihydro-1H-indene-2-carboxamide;5-[6-(dimethylamino)-2-pyridinyl]-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;5-(3-fluoro-2-pyridinyl)-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;bis(N-methyl-5-(6-methyl-2-pyridinyl)-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide).
What is the SMILES notation for N-[5-(cyclopropylsulfamoyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-5-(6-methyl-2-pyridinyl)-2,3-dihydro-1H-indene-2-carboxamide;5-[6-(dimethylamino)-2-pyridinyl]-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;5-(3-fluoro-2-pyridinyl)-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;bis(N-methyl-5-(6-methyl-2-pyridinyl)-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide)?
The canonical SMILES for N-[5-(cyclopropylsulfamoyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-5-(6-methyl-2-pyridinyl)-2,3-dihydro-1H-indene-2-carboxamide;5-[6-(dimethylamino)-2-pyridinyl]-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;5-(3-fluoro-2-pyridinyl)-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;bis(N-methyl-5-(6-methyl-2-pyridinyl)-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide) is Cc1cccc(-c2ccc3c(c2)CC(C(=O)N(C)c2nc(C)c(S(=O)(=O)NC4CC4)s2)C3)n1.Cc1cccc(-c2ccc3c(c2)CC(C(=O)N(C)c2nc(C)c(S(N)(=O)=O)s2)C3)n1.Cc1cccc(-c2ccc3c(c2)CC(C(=O)N(C)c2nc(C)c(S(N)(=O)=O)s2)C3)n1.Cc1nc(N(C)C(=O)C2Cc3ccc(-c4cccc(N(C)C)n4)cc3C2)sc1S(N)(=O)=O.Cc1nc(N(C)C(=O)C2Cc3ccc(-c4ncccc4F)cc3C2)sc1S(N)(=O)=O.
What is the InChIKey of N-[5-(cyclopropylsulfamoyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-5-(6-methyl-2-pyridinyl)-2,3-dihydro-1H-indene-2-carboxamide;5-[6-(dimethylamino)-2-pyridinyl]-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;5-(3-fluoro-2-pyridinyl)-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;bis(N-methyl-5-(6-methyl-2-pyridinyl)-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide)?
The InChIKey is JZULDSBIWLRFKS-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H26N4O3S2.C22H25N5O3S2.2C21H22N4O3S2.C20H19FN4O3S2/c1-14-5-4-6-21(25-14)17-8-7-16-11-19(13-18(16)12-17)22(29)28(3)24-26-15(2)23(32-24)33(30,31)27-20-9-10-20;1-13-21(32(23,29)30)31-22(24-13)27(4)20(28)17-10-14-8-9-15(11-16(14)12-17)18-6-5-7-19(25-18)26(2)3;2*1-12-5-4-6-18(23-12)15-8-7-14-9-17(11-16(14)10-15)19(26)25(3)21-24-13(2)20(29-21)30(22,27)28;1-11-19(30(22,27)28)29-20(24-11)25(2)18(26)15-8-12-5-6-13(9-14(12)10-15)17-16(21)4-3-7-23-17/h4-8,12,19-20,27H,9-11,13H2,1-3H3;5-9,11,17H,10,12H2,1-4H3,(H2,23,29,30);2*4-8,10,17H,9,11H2,1-3H3,(H2,22,27,28);3-7,9,15H,8,10H2,1-2H3,(H2,22,27,28).
What are the key properties of N-[5-(cyclopropylsulfamoyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-5-(6-methyl-2-pyridinyl)-2,3-dihydro-1H-indene-2-carboxamide;5-[6-(dimethylamino)-2-pyridinyl]-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;5-(3-fluoro-2-pyridinyl)-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;bis(N-methyl-5-(6-methyl-2-pyridinyl)-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide)?
N-[5-(cyclopropylsulfamoyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-5-(6-methyl-2-pyridinyl)-2,3-dihydro-1H-indene-2-carboxamide;5-[6-(dimethylamino)-2-pyridinyl]-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;5-(3-fluoro-2-pyridinyl)-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;bis(N-methyl-5-(6-methyl-2-pyridinyl)-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide) has a molecular weight of 2285.90 g/mol, XLogP of 14.62, 23 rotatable bonds, 5 hydrogen bond donors, and 31 hydrogen bond acceptors.
Where does this data come from?
All data for N-[5-(cyclopropylsulfamoyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-5-(6-methyl-2-pyridinyl)-2,3-dihydro-1H-indene-2-carboxamide;5-[6-(dimethylamino)-2-pyridinyl]-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;5-(3-fluoro-2-pyridinyl)-N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide;bis(N-methyl-5-(6-methyl-2-pyridinyl)-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2,3-dihydro-1H-indene-2-carboxamide) is sourced from PubChem (CID 159072208), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).