6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluorobenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-2-amine

C91H66Cl3F19N24O2 — CID 159075905

IUPAC6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluorobenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-2-amine
SMILESCc1nn(C)c(Cl)c1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1.Cc1nn(C)c(Cl)c1-c1cncc(Nc2ccc(OC(F)(F)F)cc2)n1.Cc1nn(C)c(Cl)c1-c1cncc(Nc2ccc(OC(F)F)cc2)n1.Fc1ccc2nc(C(F)(F)F)c(-c3cccc(Nc4ccc(C(F)(F)F)cc4)n3)n2c1.N#Cc1cc(Nc2ccc(C(F)(F)F)cc2)nc(-n2c(C3CC3)nc3ccc(F)cc32)c1
InChIInChI=1S/C23H15F4N5.C20H11F7N4.C16H13ClF3N5O.C16H13ClF3N5.C16H14ClF2N5O/c24-16-5-8-18-19(11-16)32(22(30-18)14-1-2-14)21-10-13(12-28)9-20(31-21)29-17-6-3-15(4-7-17)23(25,26)27;21-12-6-9-16-30-18(20(25,26)27)17(31(16)10-12)14-2-1-3-15(29-14)28-13-7-4-11(5-8-13)19(22,23)24;1-9-14(15(17)25(2)24-9)12-7-21-8-13(23-12)22-10-3-5-11(6-4-10)26-16(18,19)20;1-9-14(15(17)25(2)24-9)12-7-21-8-13(23-12)22-11-5-3-10(4-6-11)16(18,19)20;1-9-14(15(17)24(2)23-9)12-7-20-8-13(22-12)21-10-3-5-11(6-4-10)25-16(18)19/h3-11,14H,1-2H2,(H,29,31);1-10H,(H,28,29);3-8H,1-2H3,(H,22,23);3-8H,1-2H3,(H,22,23);3-8,16H,1-2H3,(H,21,22)
InChIKeyKAGATNPGNYDEAT-UHFFFAOYSA-N
MW1995.02 g/mol
LogP25.65
Rot. Bonds19

About 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluorobenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-2-amine

6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluorobenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-2-amine (PubChem CID 159075905) has the molecular formula C91H66Cl3F19N24O2 and a molecular weight of 1995.02 g/mol. Its IUPAC name is 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluorobenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-2-amine.

Molecular Properties

Compound Name6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluorobenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-2-amine
PubChem CID159075905
Molecular FormulaC91H66Cl3F19N24O2
Molecular Weight1995.02 g/mol
Exact Mass1992.46
IUPAC Name6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluorobenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-2-amine
SMILESCc1nn(C)c(Cl)c1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1.Cc1nn(C)c(Cl)c1-c1cncc(Nc2ccc(OC(F)(F)F)cc2)n1.Cc1nn(C)c(Cl)c1-c1cncc(Nc2ccc(OC(F)F)cc2)n1.Fc1ccc2nc(C(F)(F)F)c(-c3cccc(Nc4ccc(C(F)(F)F)cc4)n3)n2c1.N#Cc1cc(Nc2ccc(C(F)(F)F)cc2)nc(-n2c(C3CC3)nc3ccc(F)cc32)c1
InChIInChI=1S/C23H15F4N5.C20H11F7N4.C16H13ClF3N5O.C16H13ClF3N5.C16H14ClF2N5O/c24-16-5-8-18-19(11-16)32(22(30-18)14-1-2-14)21-10-13(12-28)9-20(31-21)29-17-6-3-15(4-7-17)23(25,26)27;21-12-6-9-16-30-18(20(25,26)27)17(31(16)10-12)14-2-1-3-15(29-14)28-13-7-4-11(5-8-13)19(22,23)24;1-9-14(15(17)25(2)24-9)12-7-21-8-13(23-12)22-10-3-5-11(6-4-10)26-16(18,19)20;1-9-14(15(17)25(2)24-9)12-7-21-8-13(23-12)22-11-5-3-10(4-6-11)16(18,19)20;1-9-14(15(17)24(2)23-9)12-7-20-8-13(22-12)21-10-3-5-11(6-4-10)25-16(18)19/h3-11,14H,1-2H2,(H,29,31);1-10H,(H,28,29);3-8H,1-2H3,(H,22,23);3-8H,1-2H3,(H,22,23);3-8,16H,1-2H3,(H,21,22)
InChIKeyKAGATNPGNYDEAT-UHFFFAOYSA-N
XLogP25.65
TPSA294.10 Ų
H-Bond Donors5
H-Bond Acceptors26
Rotatable Bonds19
Heavy Atoms139
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001995.02
LogP ≤ 525.65
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1026

Analyze 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluorobenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-2-amine with MolForge

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Frequently Asked Questions

What is the IUPAC name of 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluorobenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-2-amine?
The IUPAC name of 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluorobenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-2-amine (CID 159075905) is 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluorobenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-2-amine.
What is the SMILES notation for 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluorobenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-2-amine?
The canonical SMILES for 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluorobenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-2-amine is Cc1nn(C)c(Cl)c1-c1cncc(Nc2ccc(C(F)(F)F)cc2)n1.Cc1nn(C)c(Cl)c1-c1cncc(Nc2ccc(OC(F)(F)F)cc2)n1.Cc1nn(C)c(Cl)c1-c1cncc(Nc2ccc(OC(F)F)cc2)n1.Fc1ccc2nc(C(F)(F)F)c(-c3cccc(Nc4ccc(C(F)(F)F)cc4)n3)n2c1.N#Cc1cc(Nc2ccc(C(F)(F)F)cc2)nc(-n2c(C3CC3)nc3ccc(F)cc32)c1.
What is the InChIKey of 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluorobenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-2-amine?
The InChIKey is KAGATNPGNYDEAT-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H15F4N5.C20H11F7N4.C16H13ClF3N5O.C16H13ClF3N5.C16H14ClF2N5O/c24-16-5-8-18-19(11-16)32(22(30-18)14-1-2-14)21-10-13(12-28)9-20(31-21)29-17-6-3-15(4-7-17)23(25,26)27;21-12-6-9-16-30-18(20(25,26)27)17(31(16)10-12)14-2-1-3-15(29-14)28-13-7-4-11(5-8-13)19(22,23)24;1-9-14(15(17)25(2)24-9)12-7-21-8-13(23-12)22-10-3-5-11(6-4-10)26-16(18,19)20;1-9-14(15(17)25(2)24-9)12-7-21-8-13(23-12)22-11-5-3-10(4-6-11)16(18,19)20;1-9-14(15(17)24(2)23-9)12-7-20-8-13(22-12)21-10-3-5-11(6-4-10)25-16(18)19/h3-11,14H,1-2H2,(H,29,31);1-10H,(H,28,29);3-8H,1-2H3,(H,22,23);3-8H,1-2H3,(H,22,23);3-8,16H,1-2H3,(H,21,22).
What are the key properties of 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluorobenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-2-amine?
6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluorobenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-2-amine has a molecular weight of 1995.02 g/mol, XLogP of 25.65, 19 rotatable bonds, 5 hydrogen bond donors, and 26 hydrogen bond acceptors.
Where does this data come from?
All data for 6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(difluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazin-2-amine;6-(5-chloro-1,3-dimethylpyrazol-4-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;2-(2-cyclopropyl-6-fluorobenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-[6-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyridin-2-amine is sourced from PubChem (CID 159075905), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).