N-[3,3-bis(4-fluorophenyl)propyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;4-(4-fluorophenoxy)-N-[(2S)-2-phenylpropyl]piperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-3-pyridin-3-ylpyrrolidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-3-pyrazin-2-ylpyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-(pyridin-2-ylmethyl)pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]pyrrolidine-1-carboxamide

C152H166ClF12N27O13 — CID 159079463

About N-[3,3-bis(4-fluorophenyl)propyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;4-(4-fluorophenoxy)-N-[(2S)-2-phenylpropyl]piperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-3-pyridin-3-ylpyrrolidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-3-pyrazin-2-ylpyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-(pyridin-2-ylmethyl)pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]pyrrolidine-1-carboxamide

N-[3,3-bis(4-fluorophenyl)propyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;4-(4-fluorophenoxy)-N-[(2S)-2-phenylpropyl]piperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-3-pyridin-3-ylpyrrolidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-3-pyrazin-2-ylpyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-(pyridin-2-ylmethyl)pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]pyrrolidine-1-carboxamide (PubChem CID 159079463) has the molecular formula C152H166ClF12N27O13 and a molecular weight of 2842.60 g/mol. Its IUPAC name is N-[3,3-bis(4-fluorophenyl)propyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;4-(4-fluorophenoxy)-N-[(2S)-2-phenylpropyl]piperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-3-pyridin-3-ylpyrrolidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-3-pyrazin-2-ylpyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-(pyridin-2-ylmethyl)pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]pyrrolidine-1-carboxamide.

Molecular Properties

• Compound Name: N-[3,3-bis(4-fluorophenyl)propyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;4-(4-fluorophenoxy)-N-[(2S)-2-phenylpropyl]piperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-3-pyridin-3-ylpyrrolidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-3-pyrazin-2-ylpyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-(pyridin-2-ylmethyl)pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]pyrrolidine-1-carboxamide
• PubChem CID: 159079463
• Molecular Formula: C152H166ClF12N27O13
• Molecular Weight: 2842.60 g/mol
• Exact Mass: 2840.27
• IUPAC Name: N-[3,3-bis(4-fluorophenyl)propyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;4-(4-fluorophenoxy)-N-[(2S)-2-phenylpropyl]piperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-3-pyridin-3-ylpyrrolidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-3-pyrazin-2-ylpyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-(pyridin-2-ylmethyl)pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]pyrrolidine-1-carboxamide
• SMILES: COc1ccc(CCNC(=O)N2CCC(c3cccnc3)C2)cc1.C[C@H](CNC(=O)N1CCC(Oc2ccc(F)cc2)CC1)c1ccccc1.C[C@H](CNC(=O)N1CCC(c2cnccn2)C1)c1ccccc1.O=C(NCCC(c1ccc(F)cc1)c1ccc(F)cc1)N1CCC(Oc2ccc(F)cc2)CC1.O=C(NCc1ccc(C(F)(F)F)nc1)N1CCC(c2cnccn2)C1.O=C(NCc1ccc(F)cc1Cl)N1CCC(Oc2ccc(F)cc2)CC1.O=C(NCc1cccc(OC(F)(F)F)c1)N1CCC(c2cnccn2)C1.O=C(NCc1ccccn1)N1CCC(c2cnccn2)C1
• InChI: InChI=1S/C27H27F3N2O2.C21H25FN2O2.C19H19ClF2N2O2.C19H23N3O2.C18H22N4O.C17H17F3N4O2.C16H16F3N5O.C15H17N5O/c28-21-5-1-19(2-6-21)26(20-3-7-22(29)8-4-20)13-16-31-27(33)32-17-14-25(15-18-32)34-24-11-9-23(30)10-12-24;1-16(17-5-3-2-4-6-17)15-23-21(25)24-13-11-20(12-14-24)26-19-9-7-18(22)8-10-19;20-18-11-15(22)2-1-13(18)12-23-19(25)24-9-7-17(8-10-24)26-16-5-3-14(21)4-6-16;1-24-18-6-4-15(5-7-18)8-11-21-19(23)22-12-9-17(14-22)16-3-2-10-20-13-16;1-14(15-5-3-2-4-6-15)11-21-18(23)22-10-7-16(13-22)17-12-19-8-9-20-17;18-17(19,20)26-14-3-1-2-12(8-14)9-23-16(25)24-7-4-13(11-24)15-10-21-5-6-22-15;17-16(18,19)14-2-1-11(7-22-14)8-23-15(25)24-6-3-12(10-24)13-9-20-4-5-21-13;21-15(19-9-13-3-1-2-5-17-13)20-8-4-12(11-20)14-10-16-6-7-18-14/h1-12,25-26H,13-18H2,(H,31,33);2-10,16,20H,11-15H2,1H3,(H,23,25);1-6,11,17H,7-10,12H2,(H,23,25);2-7,10,13,17H,8-9,11-12,14H2,1H3,(H,21,23);2-6,8-9,12,14,16H,7,10-11,13H2,1H3,(H,21,23);1-3,5-6,8,10,13H,4,7,9,11H2,(H,23,25);1-2,4-5,7,9,12H,3,6,8,10H2,(H,23,25);1-3,5-7,10,12H,4,8-9,11H2,(H,19,21)/t;16-;;;14-,16?;;;/m.1..1.../s1
• InChIKey: KARDJAHLGWLSTA-SPQJGTAJSA-N
• XLogP: 27.28
• TPSA: 446.66 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 24
• Rotatable Bonds: 35
• Heavy Atoms: 205
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2842.60
LogP ≤ 5	27.28
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	24

Frequently Asked Questions

What is the IUPAC name of N-[3,3-bis(4-fluorophenyl)propyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;4-(4-fluorophenoxy)-N-[(2S)-2-phenylpropyl]piperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-3-pyridin-3-ylpyrrolidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-3-pyrazin-2-ylpyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-(pyridin-2-ylmethyl)pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]pyrrolidine-1-carboxamide?

The IUPAC name of N-[3,3-bis(4-fluorophenyl)propyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;4-(4-fluorophenoxy)-N-[(2S)-2-phenylpropyl]piperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-3-pyridin-3-ylpyrrolidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-3-pyrazin-2-ylpyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-(pyridin-2-ylmethyl)pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]pyrrolidine-1-carboxamide (CID 159079463) is N-[3,3-bis(4-fluorophenyl)propyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;4-(4-fluorophenoxy)-N-[(2S)-2-phenylpropyl]piperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-3-pyridin-3-ylpyrrolidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-3-pyrazin-2-ylpyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-(pyridin-2-ylmethyl)pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]pyrrolidine-1-carboxamide.

What is the SMILES notation for N-[3,3-bis(4-fluorophenyl)propyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;4-(4-fluorophenoxy)-N-[(2S)-2-phenylpropyl]piperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-3-pyridin-3-ylpyrrolidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-3-pyrazin-2-ylpyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-(pyridin-2-ylmethyl)pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]pyrrolidine-1-carboxamide?

The canonical SMILES for N-[3,3-bis(4-fluorophenyl)propyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;4-(4-fluorophenoxy)-N-[(2S)-2-phenylpropyl]piperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-3-pyridin-3-ylpyrrolidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-3-pyrazin-2-ylpyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-(pyridin-2-ylmethyl)pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]pyrrolidine-1-carboxamide is COc1ccc(CCNC(=O)N2CCC(c3cccnc3)C2)cc1.C[C@H](CNC(=O)N1CCC(Oc2ccc(F)cc2)CC1)c1ccccc1.C[C@H](CNC(=O)N1CCC(c2cnccn2)C1)c1ccccc1.O=C(NCCC(c1ccc(F)cc1)c1ccc(F)cc1)N1CCC(Oc2ccc(F)cc2)CC1.O=C(NCc1ccc(C(F)(F)F)nc1)N1CCC(c2cnccn2)C1.O=C(NCc1ccc(F)cc1Cl)N1CCC(Oc2ccc(F)cc2)CC1.O=C(NCc1cccc(OC(F)(F)F)c1)N1CCC(c2cnccn2)C1.O=C(NCc1ccccn1)N1CCC(c2cnccn2)C1.

What is the InChIKey of N-[3,3-bis(4-fluorophenyl)propyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;4-(4-fluorophenoxy)-N-[(2S)-2-phenylpropyl]piperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-3-pyridin-3-ylpyrrolidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-3-pyrazin-2-ylpyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-(pyridin-2-ylmethyl)pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]pyrrolidine-1-carboxamide?

The InChIKey is KARDJAHLGWLSTA-SPQJGTAJSA-N. The full InChI is InChI=1S/C27H27F3N2O2.C21H25FN2O2.C19H19ClF2N2O2.C19H23N3O2.C18H22N4O.C17H17F3N4O2.C16H16F3N5O.C15H17N5O/c28-21-5-1-19(2-6-21)26(20-3-7-22(29)8-4-20)13-16-31-27(33)32-17-14-25(15-18-32)34-24-11-9-23(30)10-12-24;1-16(17-5-3-2-4-6-17)15-23-21(25)24-13-11-20(12-14-24)26-19-9-7-18(22)8-10-19;20-18-11-15(22)2-1-13(18)12-23-19(25)24-9-7-17(8-10-24)26-16-5-3-14(21)4-6-16;1-24-18-6-4-15(5-7-18)8-11-21-19(23)22-12-9-17(14-22)16-3-2-10-20-13-16;1-14(15-5-3-2-4-6-15)11-21-18(23)22-10-7-16(13-22)17-12-19-8-9-20-17;18-17(19,20)26-14-3-1-2-12(8-14)9-23-16(25)24-7-4-13(11-24)15-10-21-5-6-22-15;17-16(18,19)14-2-1-11(7-22-14)8-23-15(25)24-6-3-12(10-24)13-9-20-4-5-21-13;21-15(19-9-13-3-1-2-5-17-13)20-8-4-12(11-20)14-10-16-6-7-18-14/h1-12,25-26H,13-18H2,(H,31,33);2-10,16,20H,11-15H2,1H3,(H,23,25);1-6,11,17H,7-10,12H2,(H,23,25);2-7,10,13,17H,8-9,11-12,14H2,1H3,(H,21,23);2-6,8-9,12,14,16H,7,10-11,13H2,1H3,(H,21,23);1-3,5-6,8,10,13H,4,7,9,11H2,(H,23,25);1-2,4-5,7,9,12H,3,6,8,10H2,(H,23,25);1-3,5-7,10,12H,4,8-9,11H2,(H,19,21)/t;16-;;;14-,16?;;;/m.1..1.../s1.

What are the key properties of N-[3,3-bis(4-fluorophenyl)propyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;4-(4-fluorophenoxy)-N-[(2S)-2-phenylpropyl]piperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-3-pyridin-3-ylpyrrolidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-3-pyrazin-2-ylpyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-(pyridin-2-ylmethyl)pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]pyrrolidine-1-carboxamide?

N-[3,3-bis(4-fluorophenyl)propyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;4-(4-fluorophenoxy)-N-[(2S)-2-phenylpropyl]piperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-3-pyridin-3-ylpyrrolidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-3-pyrazin-2-ylpyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-(pyridin-2-ylmethyl)pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]pyrrolidine-1-carboxamide has a molecular weight of 2842.60 g/mol, XLogP of 27.28, 35 rotatable bonds, 8 hydrogen bond donors, and 24 hydrogen bond acceptors.

Where does this data come from?

All data for N-[3,3-bis(4-fluorophenyl)propyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;N-[(2-chloro-4-fluorophenyl)methyl]-4-(4-fluorophenoxy)piperidine-1-carboxamide;4-(4-fluorophenoxy)-N-[(2S)-2-phenylpropyl]piperidine-1-carboxamide;N-[2-(4-methoxyphenyl)ethyl]-3-pyridin-3-ylpyrrolidine-1-carboxamide;N-[(2S)-2-phenylpropyl]-3-pyrazin-2-ylpyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-(pyridin-2-ylmethyl)pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[3-(trifluoromethoxy)phenyl]methyl]pyrrolidine-1-carboxamide;3-pyrazin-2-yl-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]pyrrolidine-1-carboxamide is sourced from PubChem (CID 159079463), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).